NOTES TO EDITORS. About Ardelyx Ardelyx targets specific gut transporters and receptors with drugs that address important medical issues in cardiovascular disease, diabetes and chronic kidney disease. With its approach, Ardelyx has developed drug candidates that exhibit restricted absorption across the gastrointestinal (GI) epithelia, thereby acting locally and specifically in the GI tract while avoiding systemic exposure and the potential for related systemic side effects. Until today, relatively few examples of non-systemic drugs have been developed and most of those are based on polymeric binders; Ardelyx is pioneering novel non-systemic drugs based on small molecules which may require lower doses and exhibit improved drug properties. The Company’s lead product, RDX5791, a minimally-absorbed, orally administered NHE3 sodium transport inhibitor, is being developed both for constipation-predominant irritable bowel syndrome (IBS-C) and for prevention of sodium overload in patients with kidney and heart disease. Additionally, Ardelyx has other products in early development for type 2 diabetes and renal disease. To date, Ardelyx has raised $56.0 million in venture and angel funding since it was founded in 2007. Ardelyx is located in Fremont, California. For more information, visit Ardelyx’s website at xxx.xxxxxxx.xxx. About AstraZeneca AstraZeneca is a global, innovation-driven biopharmaceutical business with a primary focus on the discovery, development and commercialisation of prescription medicines for gastrointestinal, cardiovascular, neuroscience, respiratory and inflammation, oncology and infectious disease. AstraZeneca operates in over 100 countries and its innovative medicines are used by millions of patients worldwide. For more information please visit: xxx.xxxxxxxxxxx.xxx ASTRAZENECA CONTACTS Media Enquiries UK Xxxx Xxxxx-Xxxxx +00 00 0000 0000 Xxxxx Xxxxxxxxx +00 00 0000 0000 Media Enquiries Sweden Xxx-Xxxxx Mikiver +00 0 000 000 00 Investor Enquiries Xxxxx Xxxx-Xxxxxx +00 00 0000 0000 mob: +00 0000 000000 Xxxx Hård +00 00 0000 0000 mob: +00 0000 000000 Xxxxxxx Xxxxxxxxxx +00 00 0000 0000 mob: +00 0000 000000 Xx Xxxxx +0 000 000 0000 mob: +0 000 000 0000 ARDELYX CONTACTS Investor Enquiries
NOTES TO EDITORS. Exchange rates of GBP 1 = THB 39.0592, which is the closing exchange rate as of 30 June 2019, have been used throughout this document. About Eastspring Investments Eastspring Investments is a leading Asia-based asset manager that manages over USD 216 billion (as at 30 June 2019) of assets on behalf of institutional and retail clients. Operating in Asia since 1994, Eastspring Investments is the Asian asset management business of Prudential plc, an international financial services group, and has one of the widest footprints across the region*. We provide investment solutions across a broad range of asset classes including equities, fixed income, multi asset solutions and alternatives and are committed to delivering high quality investment outcomes for our clients over the long term. Eastspring Investments is a signatory to the United Nations-supported Principles for Responsible Investment (PRI), a voluntary program which encourages best practice in environmental, social and corporate governance issues. For more information on Eastspring Investments, please visit: xxx.xxxxxxxxxx.xxx *Eastspring Investments (excluding JV companies) companies are ultimately wholly-owned / indirect subsidiaries / associate of Prudential plc of the United Kingdom. Eastspring Investments companies (including JV's) and Prudential plc are not affiliated in any manner with Prudential Financial, Inc., a company whose principal place of business is in the United States of America. About Prudential plc Prudential plc and its affiliated companies constitute one of the world’s leading financial services groups, serving 26 million customers and it has £717 billion of assets under management (as at 30 June 2019). Prudential plc is incorporated in England and Wales and is listed on the stock exchanges in London, Hong Kong, Singapore and New York. Prudential plc is not affiliated in any manner with Prudential Financial, Inc., a company whose principal place of business is in the United States of America. Footnotes 1 Eastspring will acquire GSB’s entire 25.0% stake in TFUND and a 25.1% stake from TBANK. 2 Based on GBP 1 = THB 39.0592 which is the closing exchange rate as at 30 June 2019. 3 Mutual funds under management as at 31 August 2019. 4 Mutual fund market shares; Mutual fund assets under management as at 31 August 2019.
NOTES TO EDITORS. 1. The Firm was first authorised as an investment business firm under the Investment Intermediaries Act, 1995. That authorisation was transposed to an authorisation under the MiFID Regulations on the coming into effect of those regulations on 1 November 2007.
NOTES TO EDITORS. A list of the CFs can be found here and a list of the PCFs can be found here. • Pursuant to section 21 of the 2010 Act a regulated financial service provider shall not permit a person to perform a controlled function unless: a) the regulated financial service provider is satisfied on reasonable grounds that the person complies with the Standards, and; b) the person has agreed to abide by the Standards. • The 2010 Act is available here. The Standards are available to download here. Guidance to the Standards is available to download here. • The Central Bank conducted an on-site inspection at Merrion’s premises in February 2016 utilising its ‘authorised officer’ powers pursuant to Chapter 3 of the Central Bank (Supervision and Enforcement) Act 2013, which is available to download here. • The fine reflects the application of the maximum percentage settlement discount of 30%, as per the Early Discount Scheme set out in the Central Bank’s ‘Outline of the Administrative Sanctions Procedure’ linked here.
NOTES TO EDITORS. Xxxxxxxxx Estates Founded in 1979, Xxxxxxxxx Estates is a multinational firm selling, acquiring, investing and letting exclusive residential and commercial property in prime central London on behalf of private individuals, landlords, investors, family trusts, developers and corporations, with overseas offices in the affluent destinations of Cannes, Mykonos and Xxxxxxxx. Privately owned, the firm has two partners, Xxxx Xxxxxxx and Xxxxxxxx Xxxxx, who are fully hands on and have led the company for more than 30 years, providing continuity, expertise and enthusiasm which has made Xxxxxxxxx Estates the property firm of choice for the rich and super- rich. It is a testament to the skills of the business that Xxxxxxxxx Estates has become a market leader in terms of both the number of instructions and deals conducted in excess of £10 million, with the agency awarded by Estates Gazette and Property Week the position of number one firm in the UK for generating the highest income from successful deals per fee earner. Delivered in a highly professional, personal and discrete manner, the Xxxxxxxxx Estates provides clients with a comprehensive range of services: • Sales • Acquisitions • Lettings • New development • Investment properties • Commercial property division For further information please visit xxx.xxxxxxxxx.xx.uk Xxxxxxxxx Estates 00 Xxxxxx Xxxxxx, Xxxxxxx, Xxxxxx. W1J 7TF T: +00 (0) 00 0000 0000 F: +00 (0) 00 0000 0000 E: xxxxx@xxxxxxxxx.xx.xx
NOTES TO EDITORS. 1. The Corporate Governance Requirements for Insurance Undertakings, 2015 applies to insurance undertakings (of which the Firm is one) with effect from 1 January 2016. A link to the Requirements for Insurance Undertakings is here. A statement in relation to the 2015 Requirements is here.
NOTES TO EDITORS. The Central Bank released a public statement in respect of the referral of this matter to Inquiry on 10 February 2016.
NOTES TO EDITORS. (1) The findings of the Central Bank of Ireland’s themed inspection of licensed moneylenders is available on the Central Bank’s website.
NOTES TO EDITORS. If anyone has any immediate concerns or worries about the operation of the Tax Treaty, they should send their queries to a new email address being set up by the Government so that we can address those concerns as part of the FAQs we will issue to tax and legal professionals. The email address is xxxxxxxxx.xxxxxxx@xxxxxxxxx.xxx.xx. A seminar will also be held for tax and legal professionals to enable the Tax Office and the Financial Secretary to address the financial services industry on the terms of the Tax Treaty.
NOTES TO EDITORS. WWF: With its network of National organizations, Programme and Associate offices in more than 50 countries on five continents, WWF is the world's largest and most experienced independent conservation organization. It has 700 projects employing over 3,000 people in almost 100 countries. . Conservation Partner: Aside from Lafarge, two other companies, Canon-Europe and Ogilvy & Xxxxxx are "Founding Members" of WWF's "Conservation Partners" programme, which was launched in 1998.
