Common use of Xxxxx Xxxx Clause in Contracts

Xxxxx Xxxx. Xxxxxx Xanarek -------------------------------------- Txx: 000-000-0006 Print Name: Sven H. Borho Fax: 000-000-0044 Print Titlx: Xxxxxxx; XrbiMed Advisors LLC Subscriptiox Xxxxxx: $001,962 ------------------- Shares Purchased: 35,400 ----------------------- SECURITY DELIVERY INSTRUCTIONS (IF DIFFERENT THAN NOTICE ADDRESS) [PURCHASER SIGNATURE PAGES TO SECURITIES PURCHASE AGREEMENT] KNIGHTSBRIDGE INTEGRATED HOLDINGS IV POST VENTURE, LP ---------------------------------------------------- Address for Notice: Print Entity Name ------------------ OrbiMed Advisors LLC 767 Third Avenue 00xx Xxxxx Xxx Xxxx, XX 00000

Xxxxx Xxxx. Xxxxxx Xanarek Kanarek -------------------------------------- TxxXxx: 000-000-0006 6406 Print Name: Sven H. Borho FaxFxx: 000-000-0044 6444 Print TitlxTixxx: Xxxxxxx; XrbiMed OrbiMed Advisors LLC Subscriptiox Xxxxxx: $001,962 068,041 ------------------- Shares Purchased: 35,400 19,700 ----------------------- SECURITY DELIVERY INSTRUCTIONS (IF DIFFERENT THAN NOTICE ADDRESS) [PURCHASER SIGNATURE PAGES TO SECURITIES PURCHASE AGREEMENT] KNIGHTSBRIDGE INTEGRATED HOLDINGS IV POST VENTUREHOLDINGS, V, LP ---------------------------------------------------- ----------------------------------------- Address for Notice: Print Entity Name ------------------ OrbiMed Advisors LLC 767 Third Avenue 00xx Xxxxx Xxx Xxxx, XX 00000

Xxxxx Xxxx. Xxxxxx Xanarek Kanarek -------------------------------------- TxxXxx: 000-000-0006 6406 Print Name: Sven H. Borho FaxFxx: 000-000-0044 6444 Print TitlxTixxx: Xxxxxxx; XrbiMed OrbiMed Advisors LLC Subscriptiox Xxxxxx: $001,962 023,710.69 ------------------- Shares Purchased: 35,400 49,673 ----------------------- SECURITY DELIVERY INSTRUCTIONS (IF DIFFERENT THAN NOTICE ADDRESS) [PURCHASER SIGNATURE PAGES TO SECURITIES PURCHASE AGREEMENT] KNIGHTSBRIDGE INTEGRATED HOLDINGS POST VENTURE IV POST VENTURE, LP ---------------------------------------------------- L.P. --------------------------------------- Address for Notice: Print Entity Name ------------------ OrbiMed Advisors LLC 767 Third Avenue 00xx Xxxxx Xxx Xxxx, XX 00000

Xxxxx Xxxx. Xxxxxx Xanarek Kanarek -------------------------------------- TxxXxx: 000-000-0006 6406 Print Name: Sven H. Borho FaxFxx: 000-000-0044 6444 Print TitlxTixxx: Xxxxxxx; XrbiMed OrbiMed Advisors LLC Subscriptiox Xxxxxx: $001,962 019,477 ------------------- Shares Purchased: 35,400 60,900 ----------------------- SECURITY DELIVERY INSTRUCTIONS (IF DIFFERENT THAN NOTICE ADDRESS) [PURCHASER SIGNATURE PAGES TO SECURITIES PURCHASE AGREEMENT] KNIGHTSBRIDGE INTEGRATED HOLDINGS IV POST VENTURE, VENTURE CAPITAL III LP ---------------------------------------------------- --------------------------------------- Address for Notice: Print Entity Name ------------------ OrbiMed Advisors LLC 767 Third Avenue 00xx Xxxxx Avenue, 30th Floor Xxx Xxxx, XX 00000

Xxxxx Xxxx. Xxxxxx Xanarek Xxxarek -------------------------------------- TxxTel: 000-000-0006 0000 Print Name: Sven H. Borho Fax: 000-000-0044 0000 Print TitlxTitle: Xxxxxxx; XrbiMed XxxiMed Advisors LLC Subscriptiox Xxxxxx: $001,962 00,472 ------------------- Shares Purchased: 35,400 2,400 ----------------------- SECURITY DELIVERY INSTRUCTIONS (IF DIFFERENT THAN NOTICE ADDRESS) [PURCHASER SIGNATURE PAGES TO SECURITIES PURCHASE AGREEMENT] KNIGHTSBRIDGE INTEGRATED HOLDINGS VENTURE CAPITAL IV POST VENTURE, LP ---------------------------------------------------- L.P. --------------------------------------- Address for Notice: Print Entity Name ------------------ OrbiMed Advisors LLC 767 Third Avenue 00xx Xxxxx Avenue, 30th Floor Xxx Xxxx, XX 00000

Xxxxx Xxxx. Xxxxxx Xanarek Kanarek -------------------------------------- TxxXxx: 000-000-0006 6406 Print Name: Sven H. Borho FaxFxx: 000-000-0044 6444 Print TitlxTixxx: Xxxxxxx; XrbiMed OrbiMed Advisors LLC Subscriptiox Xxxxxx: $001,962 007,080 ------------------- Shares Purchased: 35,400 36,000 ----------------------- SECURITY DELIVERY INSTRUCTIONS (IF DIFFERENT THAN NOTICE ADDRESS) [PURCHASER SIGNATURE PAGES TO SECURITIES PURCHASE AGREEMENT] KNIGHTSBRIDGE INTEGRATED HOLDINGS IV POST VENTURENETHERLANDS II, LP ---------------------------------------------------- L.P. ----------------------------------- Address for Notice: Print Entity Name ------------------ OrbiMed Advisors LLC 767 Third Avenue 00xx Xxxxx Xxx Xxxx, XX 00000

Xxxxx Xxxx. Xxxxxx Xanarek Xxxarek -------------------------------------- TxxTel: 000-000-0006 0000 Print Name: Sven H. Borho Fax: 000-000-0044 0000 Print TitlxTitle: Xxxxxxx; XrbiMed XxxiMed Advisors LLC Subscriptiox Xxxxxx: $001,962 07,768 ------------------- Shares Purchased: 35,400 5,600 ----------------------- SECURITY DELIVERY INSTRUCTIONS (IF DIFFERENT THAN NOTICE ADDRESS) [PURCHASER SIGNATURE PAGES TO SECURITIES PURCHASE AGREEMENT] KNIGHTSBRIDGE INTEGRATED HOLDINGS IV POST VENTURE, NETHERLAND I LP ---------------------------------------------------- ----------------------------- Address for Notice: Print Entity Name ------------------ OrbiMed Advisors LLC 767 Third Avenue 00xx Xxxxx Avenue, 30th Floor Xxx Xxxx, XX 00000

Xxxxx Xxxx. Xxxxxx Xanarek Xxxarek -------------------------------------- TxxTel: 000-000-0006 0000 Print Name: Sven H. Borho Fax: 000-000-0044 0000 Print TitlxTitle: Xxxxxxx; XrbiMed XxxiMed Advisors LLC Subscriptiox Xxxxxx: $001,962 021,581 ------------------- Shares Purchased: 35,400 37,700 ----------------------- SECURITY DELIVERY INSTRUCTIONS (IF DIFFERENT THAN NOTICE ADDRESS) [PURCHASER SIGNATURE PAGES TO SECURITIES PURCHASE AGREEMENT] KNIGHTSBRIDGE INTEGRATED HOLDINGS IV POST VENTURE, NETHERLANDS III - LP ---------------------------------------------------- ------------------------------------------- Address for Notice: Print Entity Name ------------------ OrbiMed Advisors LLC 767 Third Avenue 00xx Xxxxx Avenue, 30th Floor Xxx Xxxx, XX 00000

Xxxxx Xxxx. Xxxxxx Xanarek Xxxarek -------------------------------------- TxxTel: 000-000-0006 0000 Print Name: Sven H. Borho Fax: 000-000-0044 0000 Print TitlxTitle: Xxxxxxx; XrbiMed XxxiMed Advisors LLC Subscriptiox Xxxxxx: $001,962 07,768 ------------------- Shares Purchased: 35,400 5,600 ----------------------- SECURITY DELIVERY INSTRUCTIONS (IF DIFFERENT THAN NOTICE ADDRESS) [PURCHASER SIGNATURE PAGES TO SECURITIES PURCHASE AGREEMENT] KNIGHTSBRIDGE INTEGRATED HOLDINGS IV POST VENTURE, LP ---------------------------------------------------- II LIMITED ------------------------------------------- Address for Notice: Print Entity Name ------------------ OrbiMed Advisors LLC 767 Third Avenue 00xx Xxxxx Avenue, 30th Floor Xxx Xxxx, XX 00000