AGREEMENT

Exhibit 99.1

AGREEMENT

Pursuant to Rule 13d-1(k)(l) promulgated pursuant to the Securities Exchange Act of 1934, as amended, the undersigned agree that the attached Schedule 13G is being filed on behalf of each of the undersigned.

February 13, 2006	SKYLINE VENTURE PARTNERS II, L.P.
	BY:	SKYLINE VENTURE MANAGEMENT II, LLC
	ITS:	GENERAL PARTNER
	By:	/s/ Xxxx X. Xxxxxx
		Xxxx X. Xxxxxx
		Managing Director
February 13, 2006	SKYLINE VENTURE PARTNERS QUALIFIED
	PURCHASER FUND II, L.P.
	BY:	SKYLINE VENTURE MANAGEMENT II, LLC
	ITS:	GENERAL PARTNER
	By:	/s/ Xxxx X. Xxxxxx
		Xxxx X. Xxxxxx
		Managing Director
February 13, 2006	SKYLINE VENTURE MANAGEMENT II, LLC
	By:	/s/ Xxxx X. Xxxxxx
		Xxxx X. Xxxxxx
		Managing Member
February 13, 2006	SKYLINE EXPANSION FUND, L.P.
	BY:	SKYLINE EXPANSION FUND
		MANAGEMENT, LLC
	ITS:	GENERAL PARTNER
		BY:	SKYLINE VENTURE
			MANAGEMENT III, LLC
		ITS:	MANAGING MEMBER
		By:	/s/ Xxxx X. Xxxxxx
			Xxxx X. Xxxxxx
			Managing Director
February 13, 2006	SKYLINE EXPANSION FUND MANAGEMENT, LLC
	BY:	SKYLINE VENTURE MANAGEMENT III, LLC
	ITS:	MANAGING MEMBER
		By:	/s/ Xxxx X. Xxxxxx
			Xxxx X. Xxxxxx
			Managing Director
February 13, 2006	SKYLINE VENTURE MANAGEMENT III, LLC
	By:	/s/ Xxxx X. Xxxxxx
		Xxxx X. Xxxxxx
		Managing Member
February 13, 2006	By:	/s/ Xxxx X. Xxxxxx
		Xxxx X. Xxxxxx
February 13, 2006	By:	/s/ Xxxxxxxx Xxxxxx
		Xxxxxxxx Xxxxxx