MINRAD INC.

MINRAD INC.

                                                                                            November 14, 2005

Xx. Xxxx XxXxxxxxx
c/o Minrad Inc.
000 Xxxx Xxxxxx
Xxxxxxx, Xxx Xxxx 00000

Dear Xxxx:

                Reference is made to the Employment Agreement between you and Minrad, dated on or about March 29, 2004 (the "Employment Agreement").

                This letter will confirm our mutual agreement to extend the term of the Employment Agreement until December 31, 2006. If this is correct, please so confirm in the space provided below.

                                                                                      Very truly yours,
                                                                                      MINRAD INC.

                                                                                      By:  /s/ Xxxxxxx X. Xxxxx, Xx.                       
                                                                                             Xxxxxxx X. Xxxxx, Xx., Chairman

AGREED TO AND CONFIRMED

/s/ Xxxx XxXxxxxxx                                   
                Xxxx XxXxxxxxx