AMENDMENT dated 30 April 2007 of the SERVICES AND MATERIALS AGREEMENT dated 20 April 2007 By and between SCOTTISH BIOMEDICAL LIMITED T/A “SCOTTISH BIOMEDICAL” and OMEROS CORPORATION

Exhibit 10.35

AMENDMENT dated 30 April 2007

of the

SERVICES AND MATERIALS AGREEMENT dated 20 April 2007

By and between

SCOTTISH BIOMEDICAL LIMITED T/A “SCOTTISH BIOMEDICAL”

and OMEROS CORPORATION

     This is an amendment (this “Amendment”) effective 30 April 2007, between Scottish Biomedical Limited T/A “Scottish Biomedical” (“Scottish Biomedical”) and Omeros Corporation (“Omeros”) of the Services and Materials Agreement dated 20 April 2007 (“the Agreement”) related to Omeros’ PDE10 program.

     The Agreement is hereby amended to replace original Appendix 1 (pages 20-22 of the Agreement) with the corrected Appendix 1 attached hereto (amended pages 20-22).

     All other terms of the Agreement remain unchanged and in force. This Amendment is accepted and acknowledged by each party, as of the effective date set forth herein above, through the signature of its authorized representatives below:

SCOTTISH BIOMEDICAL LIMITED						OMEROS CORPORATION
By:		/s/ Xxxx Xxxxx				By:		/s/ Xxxxxxx X. Xxxxxxxxx
Name:		Xxxx Xxxxx				Name:		Xxxxxxx X. Xxxxxxxxx, M.D.
Title:		Finance Director				Title:		Chairman & CEO

† DESIGNATES PORTIONS OF THIS DOCUMENT THAT HAVE BEEN OMITTED PURSUANT TO A REQUEST FOR CONFIDENTIAL TREATMENT FILED SEPARATELY WITH THE COMMISSION

Amended 20

Appendix 1

Proposed alterations to current catechols.

     [†]

† DESIGNATES PORTIONS OF THIS DOCUMENT THAT HAVE BEEN OMITTED PURSUANT TO A REQUEST FOR CONFIDENTIAL TREATMENT FILED SEPARATELY WITH THE COMMISSION

Amended 21