27,000,000 Shares OPKO HEALTH, INC. Common Stock ($0.01 par value per Share) UNDERWRITING AGREEMENTUnderwriting Agreement • March 10th, 2011 • Opko Health, Inc. • Surgical & medical instruments & apparatus • New York
Introductory. OPKO Health, Inc., a Delaware corporation (the “Company”), proposes to issue and sell to the several underwriters named in Schedule A (the “Underwriters”) an aggregate of 27,000,000 shares of its common stock, par value $0.01 per share (the “Shares”). The 27,000,000 Shares to be sold by the Company are collectively called the “Firm Shares.” The Firm Shares include 5,333,000 shares of common stock, par value $0.01 per share, of the Company (the “Other Firm Shares”) to be purchased by the persons or entities previously agreed upon between the Company and the Underwriters. In addition, the Company has granted to the Underwriters an option to purchase up to an additional 4,050,000 Shares. The additional 4,050,000 Shares to be sold by the Company pursuant to such option are collectively called the “Optional Shares.” The Firm Shares and, if and to the extent such option is exercised, the Optional Shares are collectively called the “Offered Shares.” Jefferies & Company, Inc. (“J
