0001193125-16-712376 Sample Contracts

AMENDMENT NO. 1 TO AT-THE-MARKET ISSUANCE SALES AGREEMENT
At-the-Market Issuance Sales Agreement • September 16th, 2016 • Medicinova Inc • Pharmaceutical preparations • New York

MediciNova, Inc. (the “Company”), and MLV & Co. LLC (“MLV”) , are parties to that certain At-the-Market Issuance Sales Agreement dated May 22, 2015 (the “Original Agreement”). All capitalized terms not defined herein shall have the meanings ascribed to them in the Original Agreement. The parties, together with FBR Capital Markets & Co. (“FBR” and together with MLV, the “Agent”), intending to be legally bound, hereby amend the Original Agreement as follows (to be effective as set forth in paragraph 6 below):

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