ContractAgreement Number Incmn/108/8/Pi/33/18 • July 4th, 2022
FIRST AMENDING AGREEMENT (“AMENDING AGREEMENT”) TO AGREEMENT NUMBER INCMN/108/8/PI/33/18 DATED 18 JUNE 2018, ENTERED INTO BY THE FIRST PARTY INSTITUTO NACIONAL DE CIENCIAS MÉDICAS Y NUTRICIÓN SALVADOR ZUBIRÁN, HEREINAFTER REFERRED TO AS “THE INSTITUTE”, HERE REPRESENTED BY ITS MANAGING DIRECTOR, DR. DAVID KERSHENOBICH STALNIKOWITZ, FOR THE SECOND PARTY, REATA PHARMACEUTICALS, INC. HEREINAFTER REFERRED TO AS “THE SPONSOR”, HERE REPRESENTED BY DR. JOSÉ LUIS VIRAMONTES MADRID IN THEIR CAPACITY AS “THE CRO”, AND WITH THE INTERVENTION OF A THIRD PARTY, REPRESENTED BY DR. TATIANA SOFÍA RODRIGUEZ, IN HER CAPACITY AS PROJECT COORDINATOR AND PRINCIPAL INVESTIGATOR, HEREINAFTER “THE INVESTIGATOR”, WHEN THEY ARE JOINTLY NAMED, WILL BE REFERRED TO AS “THE PARTIES”, IN ACCORDANCE WITH THE FOLLOWING BACKGROUND, DEFINITIONS AND CLAUSES: PRIMER CONVENIO MODIFICATORIO (“CONVENIO MODIFICATORIO”) AL CONVENIO DE CONCERTACIÓN NÚMERO INCMN/108/8/PI/33/18 DE FECHA 18 DE JUNIO DE 2018, QUE CELEBRAN POR UNA PA
