Lead Compound definition

Lead Compound means any compound of lead other than galena which, when treated in the manner described below, yields to an aqueous solution of hydrochloric acid a quantity soluble lead compound exceeding, when calculated as lead monoxide, five percent of the dry weight of the portion taken analysis.

Lead Compound means any compound of lead other than galena which, when treated in the manner described below, yields to an aqueous solution of hydrochloric acid, a quantity of soluble lead compound exceeding, when calculated as lead monoxide, five per cent of the “dry weight” of the portion taken for analysis. In the case of paints and similar products and other mixtures containing oil or fat the “dry weight” means the dry weight of the material remaining after the substance has been thoroughly mixed and treated with suitable solvents to remove oil, fats, varnish or other media.

Lead Compound means that Product Candidate which is in the most advanced stage of development. VX-680 shall be the Lead Compound on the Effective Date. If there is at any time no Product Candidate in development, then the Lead Compound shall mean the next Product Candidate selected for development.

Examples of Lead Compound in a sentence

• Under no circumstances shall either Party conduct studies of any Collaboration Lead Compound in the Field except as permitted by the RMC.

• The RMC will be responsible for coordinating all aspects of all activities undertaken to identify and develop a Lead Compound that are necessary or desirable to determine whether such Lead Compound may be suitable for designation as a Collaboration Lead Compound pursuant to Section 3(b)(i).

• In addition, the RMC will be responsible for coordinating all aspects of all activities (including, but not limited to: [ * ] that will be undertaken with respect to a Collaboration Lead Compound that are necessary or desirable to enable the filing of an IND on Products based upon or incorporating such Collaboration Lead Compound, including the preparation and filing of an IND (collectively, "Pre-Clinical Development").

• The Parties, under the direction of the RMC shall conduct Pre-Clinical Development with respect to any designated Collaboration Lead Compound.

• If the RMC determines that such Lead Compound does not meet the Pre-Clinical Development Criteria, then within [ * ] of such determination each Party shall provide to the RMC a written notice as to whether it elects to designate such Lead Compound as a Collaboration Lead Compound and participate in and commit resources to conduct Pre-Clinical Development of such Collaboration Lead Compound notwithstanding that such Lead Compound does not meet the Pre-Clinical Development Criteria.

More Definitions of Lead Compound

Lead Compound means a Library Compound which meets the specific physical, chemical and/or catalytic properties established either in the Research Plan or by the Research Committee for identifying a Lead Compound. The procedure for identifying a Lead Compound is set forth on Exhibit B hereto. It is understood and agreed that any Library Compound that is transferred from Symyx to TDCC and subsequently commercialized by or under authority of TDCC or its Affiliates shall be deemed a Lead Compound.

Lead Compound means any compound of lead other than galena which, when treated in the manner described below, yields to an aqueous solution of hydrochloric acid, a quantity of soluble lead compound exceeding, when calculated as lead monoxide, five per cent of the dry weight of the portion taken for analysis. The method of treatment shall be as follows:

Lead Compound means any Programme Compound which satisfies the criteria set out in Milestone 1 in Schedule 3 for use in the Field;

Lead Compound will have the meaning assigned in Section 3.2.

Lead Compound means any Hit or Schering Compound with respect to which the Parties agree to initiate a program of medicinal chemistry to identify a Development Candidate based upon the structure of such Hit or Schering Compound.

Lead Compound means an active compound identified by Rigel in the course of Compound Screening on the basis of a Novel Validated Target pursuant to Section 5.6.

Lead Compound means an organic compound identified in screening assays and in vivo studies that shows sufficient activity to be a standard of comparison in medicinal chemistry research programs intended to identify additional compounds having superior potency, selectivity, in vivo activity, or other superior drug-like qualities.