Common use of Xxxxxxxx Xxxxxx Clause in Contracts

Xxxxxxxx Xxxxxx. Xxxxxxxx@xxx.xxx Xxx Xxxxxx Xxxxxx.Xxxxxx@xxx.xxx Xxx X. Hershey Xxx.Xxxxxxx@xxx.xxx Date: Subject: [●], 20[●] Equity Distribution Agreement – Placement Notice Gentlemen: Pursuant to the terms and subject to the conditions contained in the Equity Distribution Agreement between Catalyst Biosciences, Inc. (the “Company”), and Xxxxx Xxxxxxx & Co. (“Agent”) dated October 15, 2021 (the “Agreement”), the Company hereby requests that Agent sell up to [ ] shares of the Company’s common stock, par value $0.001 per share, at a minimum market price of $[ ] per share. Sales should begin on the date of this Placement Notice and shall continue until [ ] /[all shares are sold]. SCHEDULE 2 NOTICE PARTIES Catalyst Biosciences, Inc. Nassim Usman xxxxxx@xxxxxx.xxx Xxxxxx Xxxxxx xxxxxxx@xxxxxx.xxx Xxxxx Xxxxxxx & Co. Xxxx X. Riley Xxxx.Xxxxx@xxx.xxx Xxxxxxx X. Bassett Xxxxxxx.Xxxxxxx@xxx.xxx Connor X. Xxxxxxxx Xxxxxx.Xxxxxxxx@xxx.xxx Xxx Xxxxxx Xxxxxx.Xxxxxx@xxx.xxx Xxx X. Hershey Xxx.Xxxxxxx@xxx.xxx SCHEDULE 3 FORM OF REPRESENTATION CERTIFICATE PURSUANT TO SECTION 3(q) OF THE AGREEMENT [Date] Xxxxx Xxxxxxx & Co. 000 Xxxxxxxx Xxxx Xxxxxxxxxxx, XX 00000 Sir: The undersigned, the duly qualified and elected [●], of Catalyst Biosciences, Inc., a Delaware corporation (the “Company”), does hereby certify in such capacity and on behalf of the Company, pursuant to Section 3(q) of the Equity Distribution Agreement, dated October 15, 2021 (the “Equity Distribution Agreement”), between the Company and Xxxxx Xxxxxxx & Co., that to the best of the knowledge of the undersigned:

Xxxxxxxx Xxxxxx. Xxxxxxxx@xxx.xxx X.Xxxxxxxx@xxx.xxx Xxx Xxxxxx Xxxxxx.Xxxxxx@xxx.xxx Xxxxxx.X.Xxxxxx@xxx.xxx Xxx X. Hershey Xxx.Xxxxxxx@xxx.xxx Xxx.X.Xxxxxxx@xxx.xxx Date: Subject: [●], 20[●] Subject: Equity Distribution Agreement – Placement Notice Gentlemen: Pursuant to the terms and subject to the conditions contained in the Equity Distribution Agreement between Catalyst BiosciencesXBiotech Inc., Inc. a company incorporated under the laws of the Province of British Columbia (the “Company”), and Xxxxx Xxxxxxx & Co. (“Agent”) dated October 15April 30, 2021 2019 (the “Agreement”), the Company hereby requests that Agent sell up to [ [●] shares of the Company’s common stock, no par value $0.001 per share, at a minimum market price of $[ [●] per share. Sales should begin on the date of this Placement Notice and shall continue until [ ] /[all [[●], 20[●]/[all shares are sold]]. Schedule 1 SCHEDULE 2 NOTICE PARTIES Catalyst BiosciencesXBiotech Inc. Xxxx Xxxxxx, Inc. Nassim Usman xxxxxx@xxxxxx.xxx Chief Executive Officer xxxxxxx@xxxxxxxx.xxx Xxxxxx Xxxxxx xxxxxxx@xxxxxx.xxx Xxx, Vice President, Finance and Human Resources, and Secretary xxxx@xxxxxxxx.xxx Xxxxx Xxxxxxx & Co. Xxxx X. Riley Xxxx.Xxxxx@xxx.xxx Xxxxxxx X. Bassett Xxxxxxx.Xxxxxxx@xxx.xxx Xxxx.X.Xxxxx@xxx.xxx Connor X. Xxxxxxxx Xxxxxx.Xxxxxxxx@xxx.xxx Xxxxxx.X.Xxxxxxxx@xxx.xxx Xxx Xxxxxx Xxxxxx.Xxxxxx@xxx.xxx Xxxxxx.X.Xxxxxx@xxx.xxx Xxx X. Hershey Xxx.Xxxxxxx@xxx.xxx Xxx.X.Xxxxxxx@xxx.xxx SCHEDULE 3 FORM OF REPRESENTATION CERTIFICATE PURSUANT TO SECTION 3(q) OF THE AGREEMENT [Date●], 20[●] Xxxxx Xxxxxxx XXXXX XXXXXXX & Co. CO. U.S. Bancorp Center 000 Xxxxxxxx Xxxx Xxxxxxxxxxx, XX Xxxxxxxxx 00000 SirLadies and Gentlemen: The undersigned, the duly qualified and elected [●], of Catalyst Biosciences, XBiotech Inc., a Delaware corporation company incorporated under the laws of the Province of British Columbia (the “Company”), does hereby certify in such capacity and on behalf of the Company, pursuant to Section 3(q) of the Equity Distribution Agreement, dated October 15April 30, 2021 2019 (the “Equity Distribution Agreement”), between the Company and Xxxxx Xxxxxxx & Co., that to the best of the knowledge of the undersigned:

Xxxxxxxx Xxxxxx. Xxxxxxxx@xxx.xxx X.Xxxxxxxx@xxx.xxx Xxx Xxxxxx Xxxxxx.Xxxxxx@xxx.xxx Xxxxxx.X.Xxxxxx@xxx.xxx Xxx X. Hershey Xxx.Xxxxxxx@xxx.xxx Xxx.X.Xxxxxxx@xxx.xxx Date: Subject: [●•], 20[●20[•] Equity Distribution Agreement – Placement Notice Gentlemen: Pursuant to the terms and subject to the conditions contained in the Equity Distribution Agreement between Catalyst BiosciencesU.S. Well Services, Inc. (the ( “Company”), and Xxxxx Xxxxxxx & Co. (( “Agent”) dated October 15April 26, 2021 2022 (the “Agreement”), the Company hereby requests that Agent sell up to [ [•] shares of the Company’s Class A common stock, par value $0.001 0.0001 per share, at a minimum market price of $[ [•] per share. Sales should begin on the date of this Placement Notice and shall continue until [ [•] /[all shares are sold]. SCHEDULE 2 NOTICE PARTIES Catalyst BiosciencesU.S. Well Services, Inc. Nassim Usman xxxxxx@xxxxxx.xxx Xxxx X’Xxxxx xxxxxxx@xxxxxxxxxxxxxx.xxx Xxxxxx Xxxxxx xxxxxxx@xxxxxx.xxx Xxxxxxx xxxxxxxx@xxxxxxxxxxxxxx.xxx Xxxx Xxxxxxxx xxxxxxxxx@xxxxxxxxxxxxxx.xxx Xxxxx Xxxxxxx & Co. Xxxx X. Riley Xxxx.Xxxxx@xxx.xxx Xxxxxxx X. Bassett Xxxxxxx.Xxxxxxx@xxx.xxx Xxxx.X.Xxxxx@xxx.xxx Connor X. Xxxxxxxx Xxxxxx.Xxxxxxxx@xxx.xxx Xxxxxx.X.Xxxxxxxx@xxx.xxx Xxx Xxxxxx Xxxxxx.Xxxxxx@xxx.xxx Xxxxxx.X.Xxxxxx@xxx.xxx Xxx X. Hershey Xxx.Xxxxxxx@xxx.xxx Xxx.X.Xxxxxxx@xxx.xxx Xxx Xxxxx Xxx.Xxxxx@xxxxxxxxxx.xxx Xxxxxxx Xxxxxxx Xxxxxxx.Xxxxxxx@xxx.xxx Schedule 2 SCHEDULE 3 FORM OF REPRESENTATION CERTIFICATE PURSUANT TO SECTION 3(q4(h) OF THE AGREEMENT [Date] Xxxxx Xxxxxxx & Co. 000 Xxxxxxxx Xxxx Xxxxxxxxxxx, XX 00000 SirSir or Madam: The undersigned, the duly qualified and elected [●], Chief Executive Officer and the duly qualified and elected Chief Financial Officer of Catalyst BiosciencesU.S. Well Services, Inc., a Delaware corporation (the “Company”), does do hereby certify in such capacity and on behalf of the Company, and not in any individual capacity, pursuant to Section 3(q) of the Equity Distribution Agreement, dated October 15April 26, 2021 2022 (the “Equity Distribution Agreement”), between the Company and Xxxxx Xxxxxxx & Co., that to the best of the knowledge of the undersigned:

Xxxxxxxx Xxxxxx. Xxxxxxxx@xxx.xxx Xxx Xxxxxx Xxxxxx.Xxxxxx@xxx.xxx XxxxxxXxxxxx.Xxxxxx@xxx.xxx Xxx X. Hershey Xxx.Xxxxxxx@xxx.xxx XxxxxxxXxx.Xxxxxxx@xxx.xxx Date: Subject: [●], 20[●] Subject: Equity Distribution Agreement – Placement Notice Gentlemen: Pursuant to the terms and subject to the conditions contained in the Equity Distribution Agreement between Catalyst Biosciences, POINT Biopharma Global Inc. (the ( “Company”), and Xxxxx Xxxxxxx & Co. (( “Agent”) dated October 15July 1, 2021 2022 (the “Agreement”), the Company hereby requests that Agent sell up to [ [●] shares of the Company’s common stock, par value $0.001 0.0001 per share, at a minimum market price of $[ [●] per share. Sales should begin on the date of this Placement Notice and shall continue until [ ] [●]/[all shares are sold]. SCHEDULE 2 NOTICE PARTIES Catalyst Biosciences, POINT Biopharma Global Inc. Nassim Usman xxxxxx@xxxxxx.xxx Xxxx Xxxxxx xxxxxxx@xxxxxxxxxxxxxx.xxx Xxx XxXxxx xxxxxxx@xxxxxxxxxxxxxx.xxx Xxxxx Xxxxxx xxxxxxx@xxxxxx.xxx xxxxxxx@xxxxxxxxxxxxxx.xxx Xxxxx Xxxxxxx & Co. Xxxx X. Riley Xxxx.Xxxxx@xxx.xxx Xxxxxxx X. Bassett Xxxxxxx.Xxxxxxx@xxx.xxx Connor X. Xxxxxxxx Xxxxxx.Xxxxxxxx@xxx.xxx Xxx Xxxxxx Xxxxxx.Xxxxxx@xxx.xxx Xxx X. Hershey Xxx.Xxxxxxx@xxx.xxx SCHEDULE 3 FORM OF REPRESENTATION CERTIFICATE PURSUANT TO SECTION 3(q) OF THE AGREEMENT [Date] Xxxxx Xxxxxxx & Co. 000 Xxxxxxxx Xxxx Xxxxxxxxxxx, XX 00000 Sir: The undersigned, the duly qualified and elected [●•], of Catalyst Biosciences, POINT Biopharma Global Inc., a Delaware corporation (the “Company”), does hereby certify in such capacity and on behalf of the Company, pursuant to Section 3(q) of the Equity Distribution Agreement, dated October 15July 1, 2021 2022 (the “Equity Distribution Agreement”), between the Company and Xxxxx Xxxxxxx & Co., that to the best of the knowledge of the undersigned:

Xxxxxxxx Xxxxxx. Xxxxxxxx@xxx.xxx Xxx Xxxxxx Xxxxxx.Xxxxxx@xxx.xxx Xxx X. Hershey Xxxxxxx Xxx.Xxxxxxx@xxx.xxx Xxxx Xxxxx Xxxx.Xxxxx@xxx.xxx Xxxxxx Xxxxxx Xxxxxx.Xxxxxx@xxx.xxx Date: Subject: [●], 20[●] Equity Distribution Agreement – Placement Notice Gentlemen: Pursuant to the terms and subject to the conditions contained in the Equity Distribution Agreement by and between Catalyst BiosciencesTELA Bio, Inc. (the “Company”), ) and Xxxxx Xxxxxxx & Co. (“Agent”) ), dated October 15November 13, 2021 2023 (the “Agreement”), the Company hereby requests that Agent sell up to [ [●] shares of the Company’s common stock, par value $0.001 per share, at a minimum market price of $[ [●] per share. Sales should begin on the date of this Placement Notice and shall continue until [ [●] /[all shares are sold]. SCHEDULE 2 NOTICE PARTIES Catalyst BiosciencesTELA Bio, Inc. Nassim Usman xxxxxx@xxxxxx.xxx Xxxxxx Xxxxxx xxxxxxx@xxxxxx.xxx Xxxxxxx xxxxxxxx@xxxxxxx.xxx Xxxxxxx Xxxx xxxxx@xxxxxxx.xxx Xxxxx Xxxxxxx xxxxxxxx@xxxxxxx.xxx Xxxxx Xxxxxxx & Co. Xxxx X. Riley Xxxxx Xxxx.Xxxxx@xxx.xxx Xxxxxxx X. Bassett Xxxxxxx.Xxxxxxx@xxx.xxx Connor Xxxxxx X. Xxxxxxxx Xxxxxx.Xxxxxxxx@xxx.xxx Xxx Xxxxxx Xxxxxx.Xxxxxx@xxx.xxx Xxx X. Hershey Xxxxxxx Xxx.Xxxxxxx@xxx.xxx Xxxx Xxxxx Xxxx.Xxxxx@xxx.xxx Xxxxxx Xxxxxx Xxxxxx.Xxxxxx@xxx.xxx SCHEDULE 3 FORM OF REPRESENTATION CERTIFICATE PURSUANT TO SECTION 3(q) OF THE AGREEMENT [Date●] Xxxxx Xxxxxxx & Co. 000 Xxxxxxxx Xxxx Xxxxxxxxxxx800 Nicollet Mall Minneapolis, XX 00000 MN 55402 Sir/Madam: The undersigned, the duly qualified and elected [●], Chief Operating Officer and Chief Financial Officer of Catalyst BiosciencesTELA Bio, Inc., a Delaware corporation (the “Company”), does hereby certify in such capacity and on behalf of the Company, pursuant to Section 3(q) of the Equity Distribution Agreement, dated October 15November 13, 2021 2023 (the “Equity Distribution Agreement”), between the Company and Xxxxx Xxxxxxx & Co., that to the best of the knowledge of the undersigned:

Xxxxxxxx Xxxxxx. Xxxxxxxx@xxx.xxx Xxx Xxxxxx Xxxxxx.Xxxxxx@xxx.xxx Xxx X. Hershey Xxx.Xxxxxxx@xxx.xxx Date: Subject: [●], 20[●] Equity Distribution Agreement – Placement Notice Gentlemen: Pursuant to the terms and subject to the conditions contained in the Equity Distribution Agreement between Catalyst Biosciences, Miromatrix Medical Inc. (the ( “Company”), and Xxxxx Xxxxxxx & Co. (( “Agent”) dated October 15July, 2021 1, 2022 (the “Agreement”), the Company hereby requests that Agent sell up to [ [●] shares of the Company’s common stock, par value $0.001 0.00001 per share, at a minimum market price of $[ [●] per share. Sales should begin on the date of this Placement Notice and shall continue until [ [●] /[all shares are sold]. SCHEDULE 2 NOTICE PARTIES Catalyst BiosciencesMiromatrix Medical Inc. Xxxx Xxxx, Inc. Nassim Usman xxxxxx@xxxxxx.xxx Xxxxxx Xxxxxx xxxxxxx@xxxxxx.xxx CEO xxxxx@xxxxxxxxxx.xxx Xxx Xxxxxxx, CFO xxxxxxxx@xxxxxxxxxx.xxx Xxxxx Xxxxxxx & Co. Xxxx X. Riley Xxxx.Xxxxx@xxx.xxx Xxxxxxx X. Bassett Xxxxxxx.Xxxxxxx@xxx.xxx Connor X. Xxxxxxxx Xxxxxx.Xxxxxxxx@xxx.xxx Xxx Xxxxxx Xxxxxx.Xxxxxx@xxx.xxx Xxx X. Hershey Xxx.Xxxxxxx@xxx.xxx SCHEDULE 3 FORM OF REPRESENTATION CERTIFICATE PURSUANT TO SECTION 3(q3(Q) OF THE AGREEMENT [Date] Xxxxx Xxxxxxx & Co. 000 Xxxxxxxx Xxxx Xxxxxxxxxxx, XX 00000 Sir: The undersigned, the duly qualified and elected [●]Chief Executive Officer and Chief Financial Officer, of Catalyst Biosciences, Miromatrix Medical Inc., a Delaware corporation (the “Company”), does hereby certify in such capacity and on behalf of the Company, pursuant to Section 3(q) of the Equity Distribution Agreement, dated October 15July 1, 2021 2022 (the “Equity Distribution Agreement”), between the Company and Xxxxx Xxxxxxx & Co., that to the best of the knowledge of the undersigned:

Xxxxxxxx Xxxxxx. Xxxxxxxx@xxx.xxx Xxx Xxxxxx Xxxxxx.Xxxxxx@xxx.xxx Xxx X. Hershey Xxx.Xxxxxxx@xxx.xxx Xxxxxxx Xxx. Xxxxxxx@xxx.xxx Xxxxxxx Xxxxxxx Xxxxxxx.Xxxxxxx@xxx.xxx Date: Subject: [●], 20[●] Subject: Equity Distribution Agreement – Placement Notice Gentlemen: Pursuant to the terms and subject to the conditions contained in the Equity Distribution Agreement between Catalyst BiosciencesVIVUS, Inc. (the “Company”), ) and Xxxxx Xxxxxxx & Co. (“Agent”) dated October 15March 6, 2021 2020 (the “Agreement”), the Company hereby requests that Agent sell up to [ [¨] shares of the Company’s common stock, par value $0.001 per share, at a minimum market price of $[ [¨] per share. Sales should begin on [the date of this Placement Notice Notice]/[¨] and shall continue until [ [¨] /[all / [all such shares are sold]sold].1 1 Additional parameters may be included in accordance with Section 2(a)(i) of the Agreement. SCHEDULE 2 NOTICE PARTIES Catalyst BiosciencesVIVUS, Inc. Nassim Usman xxxxxx@xxxxxx.xxx Xxxx Xxxx Xxxx X. Oki Xxxx X. Xxxxxx Xxxxxx xxxxxxx@xxxxxx.xxx Xxxxx Xxxxxxx & Co. Xxxx X. Riley Xxxx.Xxxxx@xxx.xxx Xxxxxxx X. Bassett Xxxxxxx.Xxxxxxx@xxx.xxx Connor X. Xxxxxxxx Xxxxxx.Xxxxxxxx@xxx.xxx Xxx Xxxxxx Xxxxxx.Xxxxxx@xxx.xxx Xxx X. Hershey Xxx.Xxxxxxx@xxx.xxx Xxxxxxx Xxxxxxx Xxxxxxx.Xxxxxxx@xxx.xxx SCHEDULE 3 FORM OF REPRESENTATION CERTIFICATE PURSUANT TO SECTION 3(q) OF THE AGREEMENT [Date] Xxxxx Xxxxxxx & Co. 000 800 Xxxxxxxx Xxxx Xxxxxxxxxxx, XX 00000 Sir: The Each of the undersigned, the duly qualified and elected [●], •] or [•] of Catalyst BiosciencesVIVUS, Inc., a Delaware corporation (the “Company”), as applicable, does hereby certify certify, solely in such capacity and on behalf of the Company, and not in any individual capacity, pursuant to Section 3(q) of the Equity Distribution Agreement, dated October 15March 6, 2021 2020 (the “Equity Distribution Agreement”), between the Company and Xxxxx Xxxxxxx & Co., that to the best of the knowledge of the undersigned:

Xxxxxxxx Xxxxxx. Xxxxxxxx@xxx.xxx X.Xxxxxxxx@xxx.xxx Xxx Xxxxxx Xxxxxx.Xxxxxx@xxx.xxx Xxxxxx.X.Xxxxxx@xxx.xxx Xxx X. Hershey Xxx.Xxxxxxx@xxx.xxx Xxx.X.Xxxxxxx@xxx.xxx Date: Subject: [●], 20[●Date] Equity Distribution Agreement – Placement Notice Gentlemen: Pursuant to the terms and subject to the conditions contained in the Equity Distribution Agreement between Catalyst BiosciencesArvinas, Inc. (the “Company”), ) and Xxxxx Xxxxxxx & Co. (“Agent”) dated October 151, 2021 2019 (the “Agreement”), the Company hereby requests that Agent sell up to [ [●] shares of the Company’s common stock, par value $0.001 per share, at a minimum market price of $[ [●] per share. Sales should may begin on the date of this Placement Notice and shall continue until [ [●] /[all shares are sold]sold].1 1 Additional limitations or parameters to be specified in any individual Placement Notice as applicable. SCHEDULE 2 NOTICE PARTIES Catalyst BiosciencesArvinas, Inc. Nassim Usman xxxxxx@xxxxxx.xxx Xxxxxx Xxxxxx xxxxxxx@xxxxxx.xxx Xxxx X. Houston Xxxx.Xxxxxxx@xxxxxxx.xxx Xxxx Xxxxxxx Xxxx.Xxxxxxx@xxxxxxx.xxx Xxxxx Xxxxxxx & Co. Xxxx X. Riley Xxxx.Xxxxx@xxx.xxx Xxxxxxx X. Bassett Xxxxxxx.Xxxxxxx@xxx.xxx Xxxx.X.Xxxxx@xxx.xxx Connor X. Xxxxxxxx Xxxxxx.Xxxxxxxx@xxx.xxx Xxxxxx.X.Xxxxxxxx@xxx.xxx Xxx Xxxxxx Xxxxxx.Xxxxxx@xxx.xxx Xxxxxx.X.Xxxxxx@xxx.xxx Xxx X. Hershey Xxx.Xxxxxxx@xxx.xxx Xxx.X.Xxxxxxx@xxx.xxx SCHEDULE 3 FORM OF REPRESENTATION CERTIFICATE PURSUANT TO SECTION 3(q) OF THE AGREEMENT [Date] Xxxxx Xxxxxxx & Co. 000 Xxxxxxxx Xxxx Xxxxxxxxxxx, XX 00000 Sir: The undersigned, the duly qualified and elected [●], ] of Catalyst BiosciencesArvinas, Inc., a Delaware corporation (the “Company”), does hereby certify certify, solely in such capacity and on behalf of the CompanyCompany and not in his individual capacity, pursuant to Section 3(q) of the Equity Distribution Agreement, dated October 151, 2021 2019 (the “Equity Distribution Agreement”), between the Company and Xxxxx Xxxxxxx & Co., that to the best of the knowledge of the undersigned:

Xxxxxxxx Xxxxxx. Xxxxxxxx@xxx.xxx Xxx Xxxxxx Xxxxxx.Xxxxxx@xxx.xxx Xxx X. Hershey Xxx.Xxxxxxx@xxx.xxx Date: Subject: [●•], 20[●20[•] Equity Distribution Agreement – Placement Notice Gentlemen: Pursuant to the terms and subject to the conditions contained in the Equity Distribution Agreement between Catalyst BiosciencesInhibikase Therapeutics, Inc. (the ( “Company”), and Xxxxx Xxxxxxx & Co. (( “Agent”) dated October 15May 16, 2021 2022 (the “Agreement”), the Company hereby requests that Agent sell up to [ ] shares of the Company’s common stock, par value $0.001 per share, at a minimum market price of $[ ] per share. Sales should begin on the date of this Placement Notice and shall continue until [ ] /[all shares are sold]. SCHEDULE 2 NOTICE PARTIES Catalyst BiosciencesInhibikase Therapeutics, Inc. Nassim Usman xxxxxx@xxxxxx.xxx Xxxxxx X. Xxxxxx, Ph.D. Xxxxxx xxxxxxx@xxxxxx.xxx X. Xxxxxxxxxx Xxxxx Xxxxxxx & Co. Xxxx X. Riley Xxxx.Xxxxx@xxx.xxx Xxxxxxx X. Bassett Xxxxxxx.Xxxxxxx@xxx.xxx Connor X. Xxxxxxxx Xxxxxx.Xxxxxxxx@xxx.xxx Xxx Xxxxxx Xxxxxx.Xxxxxx@xxx.xxx Xxx X. Hershey Xxx.Xxxxxxx@xxx.xxx SCHEDULE 3 FORM OF REPRESENTATION CERTIFICATE PURSUANT TO SECTION 3(q) OF THE AGREEMENT [Date] Xxxxx Xxxxxxx & Co. 000 Xxxxxxxx Xxxx Xxxxxxxxxxx, XX 00000 Sir: The undersigned, the duly qualified and elected [●[ ], of Catalyst BiosciencesInhibikase Therapeutics, Inc., a Delaware corporation (the “Company”), does hereby certify in such capacity and on behalf of the Company, pursuant to Section 3(q) of the Equity Distribution Agreement, dated October 15May 16, 2021 2022 (the “Equity Distribution Agreement”), between the Company and Xxxxx Xxxxxxx & Co., that to the best of the knowledge of the undersigned:

Xxxxxxxx Xxxxxx. Xxxxxxxx@xxx.xxx X.Xxxxxxxx@xxx.xxx Xxx Xxxxxx Xxxxxx.Xxxxxx@xxx.xxx XxxxxxXxxxxx.X.Xxxxxx@xxx.xxx Xxx X. Hershey Xxx.Xxxxxxx@xxx.xxx XxxxxxxXxx.X.Xxxxxxx@xxx.xxx Date: Subject: [●], 20[●] Equity Distribution Agreement – Placement Notice Gentlemen: Pursuant to the terms and subject to the conditions contained in the Equity Distribution Agreement between Catalyst Evofem Biosciences, Inc. (the ( “Company”), and Xxxxx Xxxxxxx & Co. (( “Agent”) dated October 15November 18, 2021 2019 (the “Agreement”), the Company hereby requests that Agent sell up to [ [•] shares of the Company’s common stock, par value $0.001 0.0001 per share, at a minimum market price of $[ [•] per share. Sales should begin on the date of this Placement Notice and shall continue until [ [•] /[all shares are sold]. SCHEDULE 2 NOTICE PARTIES Catalyst Evofem Biosciences, Inc. Nassim Usman xxxxxx@xxxxxx.xxx Xxxxxxx Xxxxxxxxx, Chief Executive Officer Xxxxxx Xxxxxx xxxxxxx@xxxxxx.xxx X. File, Chief Financial Officer Xxxxxxxxx X. Xxxxxxxxxxx, General Counsel Xxxxx Xxxxxxx & Co. Xxxx X. Riley Xxxx.Xxxxx@xxx.xxx Xxxxxxx X. Bassett Xxxxxxx.Xxxxxxx@xxx.xxx Xxxx.X.Xxxxx@xxx.xxx Connor X. Xxxxxxxx Xxxxxx.Xxxxxxxx@xxx.xxx Xxxxxx.X.Xxxxxxxx@xxx.xxx Xxx Xxxxxx Xxxxxx.Xxxxxx@xxx.xxx Xxxxxx.X.Xxxxxx@xxx.xxx Xxx X. Hershey Xxx.Xxxxxxx@xxx.xxx Xxx.X.Xxxxxxx@xxx.xxx SCHEDULE 3 FORM OF REPRESENTATION CERTIFICATE PURSUANT TO SECTION 3(q3(Q) OF THE AGREEMENT [Date] Xxxxx Xxxxxxx & Co. 000 Xxxxxxxx Xxxx Xxxxxxxxxxx, XX 00000 Sir: The undersigned, the duly qualified and elected [●•], of Catalyst Evofem Biosciences, Inc., a Delaware corporation (the “Company”), does hereby certify in such capacity and on behalf of the Company, pursuant to Section 3(q) of the Equity Distribution Agreement, dated October 15November 18, 2021 2019 (the “Equity Distribution Agreement”), between the Company and Xxxxx Xxxxxxx & Co., that to the best of the knowledge of the undersigned:

Xxxxxxxx Xxxxxx. Xxxxxxxx@xxx.xxx X.Xxxxxxxx@xxx.xxx Xxx Xxxxxx Xxxxxx.Xxxxxx@xxx.xxx Xxxxxx.X.Xxxxxx@xxx.xxx Xxx X. Hershey Xxx.Xxxxxxx@xxx.xxx Xxx.X.Xxxxxxx@xxx.xxx Date: Subject: [●•], 20[●20[•] Equity Distribution Agreement – Placement Notice Gentlemen: Pursuant to the terms and subject to the conditions contained in the Equity Distribution Agreement between Catalyst BiosciencesFulcrum Therapeutics, Inc. (the “Company”), and Xxxxx Xxxxxxx & Co. (“Agent”) dated October 15May 9, 2021 2022 (the “Agreement”), the Company hereby requests that Agent sell up to [ [•] shares of the Company’s common stock, par value $0.001 per share, at a minimum market price of $[ [•] per share. Sales should begin on the date of this Placement Notice and shall continue until [ ] /[all [•]/[all shares are sold]. SCHEDULE 2 NOTICE PARTIES Catalyst BiosciencesFulcrum Therapeutics, Inc. Nassim Usman xxxxxx@xxxxxx.xxx Bryan Stuart xxxxx@xxxxxxxxx.xxx Xxxxxx Xxxxxxxx xxxxxxxxx@xxxxxxxxx.xxx Xxxxxx xxxxxxx@xxxxxx.xxx Xxxxxxx xxxxxxxx@xxxxxxxxx.xxx Xxxx Xxxxxxxxxx xxxxxxxxxxx@xxxxxxxxx.xxx Xxxxx Xxxxxxx & Co. Xxxxxxx Xxxxxxx Xxxxxxx.Xxxxxxx@xxx.xxx Xxxx X. Riley Xxxxx Xxxx.Xxxxx@xxx.xxx Xxxxxxx X. Bassett Xxxxxxx.Xxxxxxx@xxx.xxx Connor X. Xxxxxx Xxxxxxxx Xxxxxx.Xxxxxxxx@xxx.xxx Xxx Xxxxxx Xxxxxx.Xxxxxx@xxx.xxx Xxx X. Hershey Xxxxxxx Xxx.Xxxxxxx@xxx.xxx SCHEDULE 3 FORM OF REPRESENTATION CERTIFICATE PURSUANT TO SECTION 3(q3(Q) OF THE AGREEMENT [Date] Xxxxx Xxxxxxx & Co. 000 Xxxxxxxx Xxxx Xxxxxxxxxxx, XX 00000 Sir: The undersigned, the duly qualified and elected [●•], of Catalyst BiosciencesFulcrum Therapeutics, Inc., a Delaware corporation (the “Company”), does hereby certify solely in such capacity and on behalf of the CompanyCompany and not in his individual capacity, pursuant to Section 3(q) of the Equity Distribution Agreement, dated October 15May 9, 2021 2022 (the “Equity Distribution Agreement”), between the Company and Xxxxx Xxxxxxx & Co., that to the best of the knowledge of the undersigned:

Xxxxxxxx Xxxxxx. Xxxxxxxx@xxx.xxx Xxx Xxxxxx Xxxxxx.Xxxxxx@xxx.xxx Xxx X. Hershey Xxx.Xxxxxxx@xxx.xxx Date: Subject: [●], 20[●] Equity Distribution Agreement – Placement Notice Gentlemen: Pursuant to the terms and subject to the conditions contained in the Equity Distribution Agreement between Catalyst Biosciences, IMV Inc. (the ( “Company”), and Xxxxx Xxxxxxx & Co. (( “Agent”) dated October 15August 4, 2021 2022 (the “Agreement”), the Company hereby requests that Agent sell up to [ [●] shares of the Company’s common stockCommon Shares, no par value $0.001 per share, at a minimum market price of U.S. $[ [●] per share. Sales should begin on the date of this Placement Notice and shall continue until [ [●] /[all shares are sold]. SCHEDULE 2 NOTICE PARTIES Catalyst Biosciences, IMV Inc. Nassim Usman xxxxxx@xxxxxx.xxx Xxxxxxxx Xxxxxxx 000 Xxxxxx Xxxxxx xxxxxxx@xxxxxx.xxx Avenue, Suite 19 Dartmouth, Nova Scotia, Canada B3B 2C4 Telephone: +0 (000) 000-0000 Facsimile: +0 (000) 000-0000 Xxxxx Xxxxxxx & Co. Xxxx X. Riley Xxxx.Xxxxx@xxx.xxx Xxxxxxx X. Bassett Xxxxxxx.Xxxxxxx@xxx.xxx Connor X. Xxxxxxxx Xxxxxx.Xxxxxxxx@xxx.xxx Xxx Xxxxxx Xxxxxx.Xxxxxx@xxx.xxx Xxx X. Hershey Xxx.Xxxxxxx@xxx.xxx SCHEDULE 3 FORM OF REPRESENTATION CERTIFICATE PURSUANT TO SECTION 3(q4(o) OF THE AGREEMENT [Date] Xxxxx Xxxxxxx & Co. 000 Xxxxxxxx Xxxx Xxxxxxxxxxx, XX 00000 Sir: The undersigned, the duly qualified and elected [●[ • ], of Catalyst Biosciences, Inc., IMV Inc. a Delaware Canadian corporation (the “Company”), does hereby certify in such capacity and on behalf of the Company, pursuant to Section 3(q4(o) of the Equity Distribution Agreement, dated October 15August 4, 2021 2022 (the “Equity Distribution Agreement”), between the Company and Xxxxx Xxxxxxx & Co., that to the best of the knowledge of the undersigned:

Xxxxxxxx Xxxxxx. Xxxxxxxx@xxx.xxx Xxx Xxxxxx Xxxxxx.Xxxxxx@xxx.xxx Xxx X.Xxxxxxxx@xxx.xxx​Xxx XxxxxxXxxxxx.X.Xxxxxx@xxx.xxx​Xxx X. Hershey Xxx.Xxxxxxx@xxx.xxx DateXxxxxxxXxx.X.Xxxxxxx@xxx.xxx​Xxxxxxx Rice & Company L.L.C ​Attention: Subject​Xxxxxxx Xxxxxxxxxxxx@xxxx.xxx ​Xxxxxx Xxxxxxxxxxxxxxxx@xxxx.xxx ​Xxxxxx XxxxxxxXxxxxxx@xxxx.xxx ​ Date:​Subject: [●[ ⚫ ], 20[●] [ ⚫ ]​Amended and Restated Equity Distribution Agreement – Placement Notice Gentlemen: ​ Pursuant to the terms and subject to the conditions contained in the Amended and Restated Equity Distribution Agreement between Catalyst Biosciencesamong Independence Contract Drilling, Inc. (the “Company”), and Xxxxx Xxxxxxx ​ ​ ​ & Co. and Xxxxxxx Xxxx & Company L.L.C. (“AgentAgents”) dated October 15August 19, 2021 2021, (the “Agreement”), the Company hereby requests that Agent Agents sell up to [ ⚫ ] shares of the Company’s common stock, par value $0.001 0.01 per share, at a minimum market price of $[ ⚫ ] per share. Sales should begin on the date of this Placement Notice and shall continue until [ ⚫ ] /[all shares are sold]. ​ ​ ​ ​ ​ ​ SCHEDULE 2 ​ NOTICE PARTIES Catalyst Biosciences​ ​ ​ Independence Contract Drilling, Inc. Nassim Usman xxxxxx@xxxxxx.xxx ​ Xxxxxxx Xxxxxxxx xxxxxxxxx@xxxxxxxxxx.xxx ​ Xxxxxx Xxxxxx xxxxxxx@xxxxxx.xxx xxxxxxx@xxxxxxxxxx.xxx ​ Xxxxxxxxx Xxxxxxx xxxxxxxx@xxxxxxxxxx.xxx ​ ​ ​ Xxxxx Xxxxxxx & Co. ​ Xxxx X. Riley Xxxx.Xxxxx@xxx.xxx Xxxxxxx X. Bassett Xxxxxxx.Xxxxxxx@xxx.xxx Connor X. Xxxxxxxx Xxxxxx.Xxxxxxxx@xxx.xxx Xxx Xxxxxx Xxxxxx.Xxxxxx@xxx.xxx Xxx X. Hershey Xxx.Xxxxxxx@xxx.xxx SCHEDULE 3 FORM OF REPRESENTATION CERTIFICATE PURSUANT TO SECTION 3(q) OF THE AGREEMENT [Date] Xxxxx Xxxxxxx & Co. 000 Xxxxxxxx Xxxx Xxxxxxxxxxx, XX 00000 Sir: The undersigned, the duly qualified and elected [●], of Catalyst Biosciences, Inc., a Delaware corporation (the “Company”), does hereby certify in such capacity and on behalf of the Company, pursuant to Section 3(q) of the Equity Distribution Agreement, dated October 15, 2021 (the “Equity Distribution Agreement”), between the Company and Xxxxx Xxxxxxx & Co., that to the best of the knowledge of the undersigned:Xxxx.X.Xxxxx@xxx.xxx ​

Xxxxxxxx Xxxxxx. Xxxxxxxx@xxx.xxx Xxx Xxxxxx Xxxxxx.Xxxxxx@xxx.xxx Xxx X. Hershey Xxx.Xxxxxxx@xxx.xxx JonesTrading Institutional Services LLC Xxx Xxxxx xxxx@xxxxxxxxxxxx.xxx Xxxxx Xxxxxx xxxxxxx@xxxxxxxxxxxx.xxx Xxxx X’Xxxxxxxx xxxxx@xxxxxxxxxxxx.xxx Xxxx Xxxxxx xxxxx@xxxxxxxxxxxx.xxx Xxxx Xxxxxxx xxxxxxxx@xxxxxxxxxxxx.xxx Burke Cook xxxxx@xxxxxxxxxxxx.xxx With a copy to XXXX@Xxxxxxxxxxxx.xxx Date: Subject: [●], 20[●] Equity Distribution Agreement – Placement Notice Gentlemen: Pursuant to the terms and subject to the conditions contained in the Equity Distribution Agreement between Catalyst Biosciencesamong Day One Biopharmaceuticals, Inc. (the ( “Company”), and Xxxxx Xxxxxxx & Co. (“AgentPiper”) and JonesTrading Institutional Services LLC (“JonesTrading”), dated October 15June 1, 2021 2022 (the “Agreement”), the Company hereby requests that Agent sell [Piper/JonesTrading] sells up to [ [●] shares of the Company’s common stock, par value $0.001 0.0001 per share, at a minimum market price of $[ [●] per share. Sales should begin on the date of this Placement Notice and shall continue until [ [●] /[all shares are sold]. SCHEDULE 2 NOTICE PARTIES Catalyst BiosciencesDay One Biopharmaceuticals, Inc. Nassim Usman xxxxxx@xxxxxx.xxx Xxxxxx Xxxxxx xxxxxxx@xxxxxx.xxx xxxxxx.xxxxxx@xxxxxxxxx.xxx Xxxxxxx Xxxx II xxxxxxx.xxxx@xxxxxxxxx.xxx Xxxxx Xxxxxxx & Co. Xxxx X. Riley Xxxx.Xxxxx@xxx.xxx Xxxxxxx X. Bassett Xxxxxxx.Xxxxxxx@xxx.xxx Connor X. Xxxxxxxx Xxxxxx.Xxxxxxxx@xxx.xxx Xxx Xxxxxx Xxxxxx.Xxxxxx@xxx.xxx Xxx X. Hershey Xxx.Xxxxxxx@xxx.xxx JonesTrading Institutional Services LLC Xxx Xxxxx xxxx@xxxxxxxxxxxx.xxx Xxxxx Xxxxxx xxxxxxx@xxxxxxxxxxxx.xxx Xxxx X’Xxxxxxxx xxxxx@xxxxxxxxxxxx.xxx Xxxx Xxxxxx xxxxx@xxxxxxxxxxxx.xxx Xxxx Xxxxxxx xxxxxxxx@xxxxxxxxxxxx.xxx Burke Cook xxxxx@xxxxxxxxxxxx.xxx With a copy to XXXX@Xxxxxxxxxxxx.xxx SCHEDULE 3 FORM OF REPRESENTATION CERTIFICATE PURSUANT TO SECTION 3(q) OF THE AGREEMENT [Date] Xxxxx Xxxxxxx & Co. 000 Xxxxxxxx Xxxx Xxxxxxxxxxx, XX 00000 SirJonesTrading Institutional Services LLC 000 Xxxx 00xx Xxxxxx, 00xx Xxxxx Xxx Xxxx, XX 00000 Sirs and Madams: The undersigned, the duly qualified and elected [●], of Catalyst BiosciencesDay One Biopharmaceuticals, Inc., a Delaware corporation (the “Company”), does hereby certify in such capacity and on behalf of the Company, pursuant to Section 3(q) of the Equity Distribution Agreement, dated October 15June 1, 2021 2022 (the “Equity Distribution Agreement”), between among the Company and Company, Xxxxx Xxxxxxx & Co.Co. and JonesTrading Institutional Services LLC, that to the best of the knowledge of the undersigned:

Xxxxxxxx Xxxxxx. Xxxxxxxx@xxx.xxx Xxx Xxxxxx Xxxxxx.Xxxxxx@xxx.xxx Xxx X. Hershey Xxx.Xxxxxxx@xxx.xxx Date: Subject: [●], 20[●] Subject: Equity Distribution Agreement – Placement Notice Gentlemen: Pursuant to the terms and subject to the conditions contained in the Equity Distribution Agreement between Catalyst BiosciencesKLX Energy Services Holdings, Inc. (the ( “Company”), ) and Xxxxx Xxxxxxx & Co. (( “Agent”) dated October 15June 14, 2021 (the “Agreement”), the Company hereby requests that the Agent sell up to [ [●] shares of the Company’s common stock, par value $0.001 0.01 per share, at a minimum market price of $[ [●] per share. Sales should begin on the date of this Placement Notice and shall continue until [ [●] /[all shares are sold]. SCHEDULE 2 NOTICE PARTIES Catalyst BiosciencesKLX Energy Services Holdings, Inc. Nassim Usman xxxxxx@xxxxxx.xxx Xxxxxxxxxxx Xxxxx xxxxxx@xxxxxxxxx.xxx Xxxxxx Xxxxxx xxxxxxx@xxxxxx.xxx xxxxxxx@xxxxxxxxx.xxx Xxx Xxxxxxxxxxxx xxxx@xxxxxxxxx.xxx Xxxxx Xxxxxxx & Co. Xxxx X. Riley Xxxx.Xxxxx@xxx.xxx Xxxxxxx X. Bassett Xxxxxxx.Xxxxxxx@xxx.xxx Connor X. Xxxxxxxx Xxxxxx.Xxxxxxxx@xxx.xxx Xxx Xxxxxx Xxxxxx.Xxxxxx@xxx.xxx Xxx X. Hershey Xxx.Xxxxxxx@xxx.xxx SCHEDULE 3 FORM OF REPRESENTATION CERTIFICATE PURSUANT TO SECTION 3(q) OF THE AGREEMENT [Date●], 20[●] Xxxxx Xxxxxxx & Co. 000 Xxxxxxxx Xxxx Xxxxxxxxxxx, XX 00000 SirSir or Madam: The undersigned, the duly qualified and elected [●], of Catalyst BiosciencesKLX Energy Services Holdings, Inc., a Delaware corporation (the “Company”), does hereby certify in such capacity and on behalf of the Company, pursuant to Section 3(q) of the Equity Distribution Agreement, dated October 15June 14, 2021 (the “Equity Distribution Agreement”), between the Company and Xxxxx Xxxxxxx & Co., that he or she has carefully examined the Registration Statement, the Prospectus, and any Permitted Free Writing Prospectus, and any amendments thereof or supplements thereto (including any documents filed under the Exchange Act and deemed to be incorporated by reference into the base prospectus, the Prospectus and any Permitted Free Writing Prospectus), and to the best of the knowledge of the undersigned:

Xxxxxxxx Xxxxxx. Xxxxxxxx@xxx.xxx X.Xxxxxxxx@xxx.xxx Xxx Xxxxxx Xxxxxx.Xxxxxx@xxx.xxx Xxxxxx.X.Xxxxxx@xxx.xxx Xxx X. Hershey Xxx.Xxxxxxx@xxx.xxx Xxx.X.Xxxxxxx@xxx.xxx Date: Subject: [●•], 20[●20[•] Equity Distribution Agreement – Placement Notice Gentlemen: Pursuant to the terms and subject to the conditions contained in the Equity Distribution Agreement Agreement, dated June 11, 2018 (the “Agreement”), between Catalyst BiosciencesAlpine Immune Sciences, Inc. (the “Company”), ) and Xxxxx Xxxxxxx & Co. (the “Agent”) dated October 15, 2021 (the “Agreement”), the Company hereby requests that Agent sell up to [ [•] shares of the Company’s common stock, par value $0.001 per share, at a minimum market price of $[ [•] per share. Sales should begin on the date of this Placement Notice and shall continue until [ [•] /[all such shares are sold]. SCHEDULE 2 NOTICE PARTIES Catalyst BiosciencesAlpine Immune Sciences, Inc. Nassim Usman xxxxxx@xxxxxx.xxx Xxxxxxxx Gold xxxxx@xxxxxxxxx.xxx Xxxx Xxxxxx Xxxxxx xxxxxxx@xxxxxx.xxx xxxx.xxxxxx@XxxxxxXxxxxxXxxxxxxx.xxx Xxxxxxx Xxxxxxxxx xxxxxxx.xxxxxxxxx@xxxxxxxxxxxxxxxxxxxx.xxx Xxxxx Xxxxxxx & Co. Xxxx X. Riley Xxxx.Xxxxx@xxx.xxx Xxxxxxx X. Bassett Xxxxxxx.Xxxxxxx@xxx.xxx Xxxx.X.Xxxxx@xxx.xxx Connor X. Xxxxxxxx Xxxxxx.Xxxxxxxx@xxx.xxx Xxxxxx.X.Xxxxxxxx@xxx.xxx Xxx Xxxxxx Xxxxxx.Xxxxxx@xxx.xxx Xxxxxx.X.Xxxxxx@xxx.xxx Xxx X. Hershey Xxx.Xxxxxxx@xxx.xxx Xxx.X.Xxxxxxx@xxx.xxx SCHEDULE 3 FORM OF REPRESENTATION CERTIFICATE PURSUANT TO SECTION 3(q5(H) OF THE EQUITY DISTRIBUTION AGREEMENT [Date] Xxxxx Xxxxxxx & Co. 000 Xxxxxxxx Xxxx Xxxxxxxxxxx, XX 00000 Sir: The undersigned, the duly qualified and elected [●•], of Catalyst BiosciencesAlpine Immune Sciences, Inc., a Delaware corporation (the “Company”), does hereby certify in such capacity and on behalf of the Company, pursuant to Section 3(q5(h) of the Equity Distribution Agreement, dated October 15June 11, 2021 2018 (the “Equity Distribution Agreement”), between the Company and Xxxxx Xxxxxxx & Co., that to the best of the knowledge of the undersigned:

Xxxxxxxx Xxxxxx. Xxxxxxxx@xxx.xxx X.Xxxxxxxx@xxx.xxx Xxx Xxxxxx Xxxxxx.Xxxxxx@xxx.xxx Xxxxxx.X.Xxxxxx@xxx.xxx Xxx X. Hershey Xxx.Xxxxxxx@xxx.xxx Xxx.X.Xxxxxxx@xxx.xxx Date: Subject: [●•], 20[●20[•] Equity Distribution Agreement – Placement Notice Gentlemen: Pursuant to the terms and subject to the conditions contained in the Equity Distribution Agreement between Catalyst BiosciencesAravive, Inc. (the ( “Company”), and Xxxxx Xxxxxxx & Co. (( “Agent”) dated October 15March 26, 2021 2019 (the “Agreement”), the Company hereby requests that Agent sell up to [ [•] shares of the Company’s common stock, par value $0.001 0.0001 per share, at a minimum market price of $[ [•] per share. Sales should begin on the date of this Placement Notice and shall continue until [ ] /[all [•]/[all shares are sold]. SCHEDULE 2 NOTICE PARTIES Catalyst BiosciencesAravive, Inc. Nassim Usman xxxxxx@xxxxxx.xxx Xxxxxx Xxxxxx xxxxxxx@xxxxxx.xxx Xxx Xxxxxxx, Chief Executive Officer xxxxxxxx@xxxxxxx.xxx Xxxxx Xxxx, Chief Financial Officer xxxxx@xxxxxxx.xxx Xxxxx Xxxx, Vice President/Finance and Principal Accounting Officer xxxxx@xxxxxxx.xxx Xxxxx Xxxxxxx & Co. Xxxx X. Riley Xxxx.Xxxxx@xxx.xxx Xxxxxxx X. Bassett Xxxxxxx.Xxxxxxx@xxx.xxx Xxxx.X.Xxxxx@xxx.xxx Connor X. Xxxxxxxx Xxxxxx.Xxxxxxxx@xxx.xxx Xxxxxx.X.Xxxxxxxx@xxx.xxx Xxx Xxxxxx Xxxxxx.Xxxxxx@xxx.xxx Xxxxxx.X.Xxxxxx@xxx.xxx Xxx X. Hershey Xxx.Xxxxxxx@xxx.xxx Xxx.X.Xxxxxxx@xxx.xxx SCHEDULE 3 FORM OF REPRESENTATION CERTIFICATE PURSUANT TO SECTION 3(q3(Q) OF THE AGREEMENT [Date•], 20[•] Xxxxx Xxxxxxx & Co. 000 Xxxxxxxx Xxxx Xxxxxxxxxxx, XX 00000 Sir: The undersigned, the duly qualified and elected [●•], of Catalyst BiosciencesAravive, Inc., a Delaware corporation (the “Company”), does hereby certify in such capacity and on behalf of the Company, pursuant to Section 3(q) of the Equity Distribution Agreement, dated October 15March 26, 2021 2019 (the “Equity Distribution Agreement”), between the Company and Xxxxx Xxxxxxx & Co., that to the best of the knowledge of the undersigned:

Xxxxxxxx Xxxxxx. Xxxxxxxx@xxx.xxx Xxx Xxxxxx Xxxxxx.Xxxxxx@xxx.xxx Xxx X. Hershey Xxx.Xxxxxxx@xxx.xxx Date: Subject: [●], 20[●] Equity Distribution Agreement – Placement Notice Gentlemen: Pursuant to the terms and subject to the conditions contained in the Equity Distribution Agreement between Catalyst Biosciences, IMV Inc. (the ( “Company”), and Xxxxx Xxxxxxx & Co. (( “Agent”) dated October 15June 30, 2021 2020 (the “Agreement”), the Company hereby requests that Agent sell up to [ [●] shares of the Company’s common stockCommon Shares, no par value $0.001 per share, at a minimum market price of U.S. $[ [●] per share. Sales should begin on the date of this Placement Notice and shall continue until [ [●] /[all shares are sold]. SCHEDULE 2 NOTICE PARTIES Catalyst Biosciences, IMV Inc. Nassim Usman xxxxxx@xxxxxx.xxx Xxxxxx Xxxxx 000 Xxxxxx Xxxxxx xxxxxxx@xxxxxx.xxx Avenue, Suite 19 Dartmouth, Nova Scotia, Canada B3B 2C4 Telephone: +0 (000) 000-0000 Facsimile: +0 (000) 000-0000 Xxxxx Xxxxxxx & Co. Xxxx X. Riley Xxxx.Xxxxx@xxx.xxx Xxxxxxx X. Bassett Xxxxxxx.Xxxxxxx@xxx.xxx Connor X. Xxxxxxxx Xxxxxx.Xxxxxxxx@xxx.xxx Xxx Xxxxxx Xxxxxx.Xxxxxx@xxx.xxx Xxx X. Hershey Xxx.Xxxxxxx@xxx.xxx SCHEDULE 3 FORM OF REPRESENTATION CERTIFICATE PURSUANT TO SECTION 3(q4(o) OF THE AGREEMENT [Date] Xxxxx Xxxxxxx & Co. 000 Xxxxxxxx Xxxx Xxxxxxxxxxx, XX 00000 Sir: The undersigned, the duly qualified and elected [●•], of Catalyst Biosciences, Inc., IMV Inc. a Delaware Canadian corporation (the “Company”), does hereby certify in such capacity and on behalf of the Company, pursuant to Section 3(q4(o) of the Equity Distribution Agreement, dated October 15June 30, 2021 2020 (the “Equity Distribution Agreement”), between the Company and Xxxxx Xxxxxxx & Co., that to the best of the knowledge of the undersigned:

Xxxxxxxx Xxxxxx. Xxxxxxxx@xxx.xxx Xxx Xxxxxx Xxxxxx.Xxxxxx@xxx.xxx Xxx X. Hershey Xxx.Xxxxxxx@xxx.xxx Date: [•], 20[•] Subject: [●], 20[●] Equity Distribution Agreement – Placement Notice Gentlemen: Pursuant to the terms and subject to the conditions contained in the Equity Distribution Agreement between Catalyst BiosciencesCodexis, Inc. (the ( “Company”), and Xxxxx Xxxxxxx & Co. (( “Agent”) dated October 15May 7, 2021 (the “Agreement”), the Company hereby requests that Agent sell up to [ [•] shares of the Company’s common stock, par value $0.001 0.0001 per share, at a minimum market price of $[ [•] per share. Sales should begin on the date of this Placement Notice and shall continue until [ [•] /[all / [all shares are sold]. SCHEDULE 2 NOTICE PARTIES Catalyst BiosciencesCodexis, Inc. Nassim Usman xxxxxx@xxxxxx.xxx Xxxx Xxxxxx xxxx.xxxxxx@xxxxxxx.xxx Xxxx Xxxxxx xxxxxxx@xxxxxx.xxx xxxx.xxxxxx@xxxxxxx.xxx Xxxxxx XxxXxxxxx Xxxxxx.xxxxxxxxx@xxxxxxx.xxx Xxxxxxx Sabalot Xxxxxxx.xxxxxxx@xxxxxxx.xxx Xxxxxxxx Xxxxxx xxxxxxxx.xxxxxx@xxxxxxx.xxx Xxxxx Xxxxxxx & Co. Xxxx X. Riley Xxxx.Xxxxx@xxx.xxx Xxxxxxx X. Bassett Xxxxxxx.Xxxxxxx@xxx.xxx Connor X. Xxxxxxxx Xxxxxx.Xxxxxxxx@xxx.xxx Xxx Xxxxxx Xxxxxx.Xxxxxx@xxx.xxx Xxx X. Hershey Xxx.Xxxxxxx@xxx.xxx SCHEDULE 3 FORM OF REPRESENTATION CERTIFICATE PURSUANT TO SECTION 3(q) OF THE AGREEMENT [Date] Xxxxx Xxxxxxx & Co. 000 Xxxxxxxx Xxxx Xxxxxxxxxxx, XX 00000 Sir: The undersigned, the duly qualified and elected [●], Chief Executive Officer and Chief Financial Officer of Catalyst BiosciencesCodexis, Inc., a Delaware corporation (the “Company”), does do hereby certify in such capacity and on behalf of the Company, pursuant to Section 3(q) of the Equity Distribution Agreement, dated October 15May 7, 2021 (the “Equity Distribution Agreement”), between the Company and Xxxxx Xxxxxxx & Co., that to the best of the knowledge of the undersigned:

Xxxxxxxx Xxxxxx. Xxxxxxxx@xxx.xxx Xxx Xxxxxx Xxxxxx.Xxxxxx@xxx.xxx Xxx X. Hershey Xxx.Xxxxxxx@xxx.xxx Date: [•], 20[•] Subject: [●], 20[●] Equity Distribution Agreement – Placement Notice Gentlemen: Pursuant to the terms and subject to the conditions contained in the Equity Distribution Agreement between Catalyst Cytek Biosciences, Inc. (the “Company”), and Xxxxx Xxxxxxx & Co. (“Agent”) dated October 15August 26, 2021 2022 (the “Agreement”), the Company hereby requests that Agent sell up to [ [•] shares of the Company’s common stock, par value $0.001 per share, at a minimum market price of $[ [•] per share. Sales should begin on the date of this Placement Notice and shall continue until [ [•] /[all shares are sold]. SCHEDULE 2 NOTICE PARTIES Catalyst Cytek Biosciences, Inc. Nassim Usman xxxxxx@xxxxxx.xxx Xxxxxx Xxxxx xxxxxx@xxxxxxxx.xxx Xxxxxx xxxxxxx@xxxxxx.xxx Xxxxxxxxx xxxxxxxxxx@xxxxxxxx.xxx Xxxxxxx Xxxxxxx xxxxxxxx@xxxxxxxx.xxx Xxxxx Xxxxxxx & Co. Xxxx X. Riley Xxxx.Xxxxx@xxx.xxx Xxxxxxx X. Bassett Xxxxxxx.Xxxxxxx@xxx.xxx Connor Xxxxxx X. Xxxxxxxx Xxxxxx.Xxxxxxxx@xxx.xxx Xxx Xxxxxx Xxxxxx.Xxxxxx@xxx.xxx Xxx X. Hershey Xxx.Xxxxxxx@xxx.xxx SCHEDULE 3 FORM OF REPRESENTATION CERTIFICATE PURSUANT TO SECTION [3(q) )] OF THE AGREEMENT [Date] Xxxxx Xxxxxxx & Co. 000 Xxxxxxxx Xxxx Xxxxxxxxxxx, XX 00000 Sir: The undersigned, the duly qualified and elected [●], Chief Executive Officer or Chief Financial Officer of Catalyst Cytek Biosciences, Inc., a Delaware corporation (the “Company”), does hereby certify in such capacity and on behalf of the Company, pursuant to Section 3(q) of the Equity Distribution Agreement, dated October 15August 26, 2021 2022 (the “Equity Distribution Agreement”), between the Company and Xxxxx Xxxxxxx & Co., that to the best of the knowledge of the undersigned:

Xxxxxxxx Xxxxxx. Xxxxxxxx@xxx.xxx X.Xxxxxxxx@xxx.xxx Xxx Xxxxxx Xxxxxx.Xxxxxx@xxx.xxx Xxxxxx.X.Xxxxxx@xxx.xxx Xxx X. Hershey Xxx.Xxxxxxx@xxx.xxx Xxx.X.Xxxxxxx@xxx.xxx Date: Subject: [●•], 20[●20[•] Aptevo Therapeutics Inc. – Equity Distribution Agreement – Placement Notice Ladies and Gentlemen: Pursuant to the terms and subject to the conditions contained in the Equity Distribution Agreement Agreement, dated November 9, 2017 (the “Agreement”), between Catalyst Biosciences, Aptevo Therapeutics Inc. (the “Company”), ) and Xxxxx Xxxxxxx & Co. (the “Agent”) dated October 15, 2021 (the “Agreement”), the Company hereby requests that the Agent sell up to [ [•] shares of the Company’s common stock, par value $0.001 per share, at a minimum market price of $[ [•] per share. Sales should begin on the date of this Placement Notice and shall continue until [ ] /[all [•]/[all such shares are sold]. Schedule 1 US-DOCS\95271282.8 SCHEDULE 2 NOTICE PARTIES Catalyst Biosciences, Aptevo Therapeutics Inc. Nassim Usman xxxxxx@xxxxxx.xxx Xxxxxx Xxxxxx xxxxxxx@xxxxxx.xxx Xxxxx xxxxxx@xxxx.xxx Jeff Lamothe xxxxxxx@xxxx.xxx Xxxxxxx Xxxxxxxx xxxxxxxxx@xxxx.xxx Xxxxx Xxxxxxx & Co. Xxxx X. Riley Xxxx.Xxxxx@xxx.xxx Xxxxxxx X. Bassett Xxxxxxx.Xxxxxxx@xxx.xxx Xxxx.X.Xxxxx@xxx.xxx Connor X. Xxxxxxxx Xxxxxx.Xxxxxxxx@xxx.xxx Xxxxxx.X.Xxxxxxxx@xxx.xxx Xxx Xxxxxx Xxxxxx.Xxxxxx@xxx.xxx Xxxxxx.X.Xxxxxx@xxx.xxx Xxx X. Hershey Xxx.Xxxxxxx@xxx.xxx Xxx.X.Xxxxxxx@xxx.xxx Schedule 2 US-DOCS\95271282.8 SCHEDULE 3 FORM OF REPRESENTATION CERTIFICATE PURSUANT TO SECTION 3(q3(Q) OF THE AGREEMENT [Date] Xxxxx Xxxxxxx & Co. 000 Xxxxxxxx Xxxx Xxxxxxxxxxx, XX 00000 SirLadies and Gentlemen: The undersigned, the duly qualified and elected [●•], of Catalyst Biosciences, Aptevo Therapeutics Inc., a Delaware corporation (the “Company”), does hereby certify in such capacity and on behalf of the Company, pursuant to Section 3(q) of the Equity Distribution Agreement, dated October 15November [•], 2021 2017 (the “Equity Distribution Agreement”), between the Company and Xxxxx Xxxxxxx & Co., that to the best of the knowledge of the undersigned:

Xxxxxxxx Xxxxxx. Xxxxxxxx@xxx.xxx X.Xxxxxxxx@xxx.xxx Xxx Xxxxxx Xxxxxx.Xxxxxx@xxx.xxx Xxxxxx.X.Xxxxxx@xxx.xxx Xxx X. Hershey Xxx.Xxxxxxx@xxx.xxx Xxx.X.Xxxxxxx@xxx.xxx Date: Subject: [●], 20[●] Subject: Equity Distribution Agreement – Placement Notice Gentlemen: Pursuant to the terms and subject to the conditions contained in the Equity Distribution Agreement between Catalyst BiosciencesAquestive Therapeutics, Inc. (the ( “Company”), and Xxxxx Xxxxxxx & Co. (“Agent”) dated October 15September 11, 2021 2019 (the “Agreement”), the Company hereby requests that Agent sell up to [ [●] shares of the Company’s common stock, par value $0.001 per share, at a minimum market price of $[ [●] per share. Sales should begin on the date of this Placement Notice and shall continue until [ [●] /[all shares are sold]. SCHEDULE 2 NOTICE PARTIES Catalyst BiosciencesAquestive Therapeutics, Inc. Nassim Usman xxxxxx@xxxxxx.xxx Xxxxx X. Xxxxxxx xxxxxxxx@xxxxxxxxx.xxx Xxxx X. Xxxxxxx xxxxxxxx@xxxxxxxxx.xxx Xxxxxx Xxxxxx xxxxxxx@xxxxxx.xxx XXxxxxx@xxxxxxxxx.xxx Xxxxx Xxxxxxx & Co. Xxxx X. Riley Xxxx.Xxxxx@xxx.xxx Xxxxxxx X. Bassett Xxxxxxx.Xxxxxxx@xxx.xxx Xxxx.X.Xxxxx@xxx.xxx Connor X. Xxxxxxxx Xxxxxx.Xxxxxxxx@xxx.xxx Xxxxxx.X.Xxxxxxxx@xxx.xxx Xxx Xxxxxx Xxxxxx.Xxxxxx@xxx.xxx Xxxxxx.X.Xxxxxx@xxx.xxx Xxx X. Hershey Xxx.Xxxxxxx@xxx.xxx Xxx.X.Xxxxxxx@xxx.xxx SCHEDULE 3 FORM OF REPRESENTATION CERTIFICATE PURSUANT TO SECTION 3(q3(Q) OF THE AGREEMENT [Date] Xxxxx Xxxxxxx & Co. 000 Xxxxxxxx Xxxx Xxxxxxxxxxx, XX 00000 Sir: The undersigned, the duly qualified and elected [●], of Catalyst BiosciencesAquestive Therapeutics, Inc., a Delaware corporation (the “Company”), does hereby certify certify, solely in such capacity and on behalf of the CompanyCompany and not in his individual capacity, pursuant to Section 3(q) of the Equity Distribution Agreement, dated October 15September 11, 2021 2019 (the “Equity Distribution Agreement”), between the Company and Xxxxx Xxxxxxx & Co., that to the best of the knowledge of the undersigned:

Xxxxxxxx Xxxxxx. Xxxxxxxx@xxx.xxx X.Xxxxxxxx@xxx.xxx Xxx Xxxxxx Xxxxxx.Xxxxxx@xxx.xxx Xxxxxx.X.Xxxxxx@xxx.xxx Xxx X. Hershey Xxx.Xxxxxxx@xxx.xxx Xxx.X.Xxxxxxx@xxx.xxx Date: Subject: [●•], 20[●20[•] Equity Distribution Agreement – Placement Notice Gentlemen: Pursuant to the terms and subject to the conditions contained in the Equity Distribution Agreement between Catalyst BiosciencesChemoCentryx, Inc. (the ( “Company”), and Xxxxx Xxxxxxx & Co. (( “Agent”) dated October 15December 4, 2021 2018 (the “Agreement”), the Company hereby requests that Agent sell up to [ [•] shares of the Company’s common stock, par value $0.001 per share, at a minimum market price of $[ [•] per share. Sales should begin on the date of this Placement Notice and shall continue until [ [•] /[all shares are sold]. SCHEDULE 2 NOTICE PARTIES Catalyst BiosciencesChemoCentryx, Inc. Nassim Usman xxxxxx@xxxxxx.xxx Xxxxxx X. Xxxxxx, Ph.D. XXxxxxx@xxxxxxxxxxxx.xxx Xxxxx X. Xxxxxx xxxxxxx@xxxxxx.xxx XXxxxxx@xxxxxxxxxxxx.xxx Xxxxx Xxxxxxx & Co. Xxxx X. Riley Xxxx.Xxxxx@xxx.xxx Xxxxxxx X. Bassett Xxxxxxx.Xxxxxxx@xxx.xxx Xxxx.X.Xxxxx@xxx.xxx Connor X. Xxxxxxxx Xxxxxx.Xxxxxxxx@xxx.xxx Xxxxxx.X.Xxxxxxxx@xxx.xxx Xxx Xxxxxx Xxxxxx.Xxxxxx@xxx.xxx Xxxxxx.X.Xxxxxx@xxx.xxx Xxx X. Hershey Xxx.Xxxxxxx@xxx.xxx Xxx.X.Xxxxxxx@xxx.xxx SCHEDULE 3 FORM OF REPRESENTATION CERTIFICATE PURSUANT TO SECTION 3(q3(Q) OF THE AGREEMENT [Date•], 20[•] Xxxxx Xxxxxxx & Co. 000 Xxxxxxxx Xxxx Xxxxxxxxxxx, XX 00000 Sir: The undersigned, the duly qualified and elected [●•], of Catalyst BiosciencesChemoCentryx, Inc., a Delaware corporation (the “Company”), does hereby certify in such capacity and on behalf of the Company, pursuant to Section 3(q) of the Equity Distribution Agreement, dated October 15December 4, 2021 2018 (the “Equity Distribution Agreement”), between the Company and Xxxxx Xxxxxxx & Co., that to the best of the knowledge of the undersigned:

Xxxxxxxx Xxxxxx. Xxxxxxxx@xxx.xxx X.Xxxxxxxx@xxx.xxx Xxx Xxxxxx Xxxxxx.Xxxxxx@xxx.xxx Xxxxxx.X.Xxxxxx@xxx.xxx Xxx X. Hershey Xxx.Xxxxxxx@xxx.xxx Xxx.X.Xxxxxxx@xxx.xxx Date: Subject: [●[ ● ], 20[●[ ● ] Equity Distribution Agreement – Placement Notice Gentlemen: Pursuant to the terms and subject to the conditions contained in the Equity Distribution Agreement between Catalyst BiosciencesEndologix, Inc. (the “Company”), and Xxxxx Xxxxxxx & Co. (“Agent”) dated October 15August 13, 2021 2019 (the “Agreement”), the Company hereby requests that Agent sell up to [ ● ] shares of the Company’s common stock, par value $0.001 per share, at a minimum market price of $[ ● ] per share. Sales should begin on the date of this Placement Notice and shall continue until [ ● ] /[all shares are sold]. SCHEDULE 2 NOTICE PARTIES Catalyst BiosciencesEndologix, Inc. Nassim Usman xxxxxx@xxxxxx.xxx Xxxx Xxxxxxxxxx, Chief Executive Officer xxxxxxxxxxx@xxxxxxxxx.xxx Xxxxxx Xxxxxxx, Chief Financial Officer xxxxxxxx@xxxxxxxxx.xxx Xxxxxx xxxxxxx@xxxxxx.xxx Xxxxxx, General Counsel xxxxxxx@xxxxxxxxx.xxx Xxxxx Xxxxxxx & Co. Xxxx X. Riley Xxxx.Xxxxx@xxx.xxx Xxxxxxx X. Bassett Xxxxxxx.Xxxxxxx@xxx.xxx Xxxx.X.Xxxxx@xxx.xxx Connor X. Xxxxxxxx Xxxxxx.Xxxxxxxx@xxx.xxx Xxxxxx.X.Xxxxxxxx@xxx.xxx Xxx Xxxxxx Xxxxxx.Xxxxxx@xxx.xxx Xxxxxx.X.Xxxxxx@xxx.xxx Xxx X. Hershey Xxx.Xxxxxxx@xxx.xxx Xxx.X.Xxxxxxx@xxx.xxx SCHEDULE 3 FORM OF REPRESENTATION CERTIFICATE PURSUANT TO SECTION 3(q) OF THE AGREEMENT [Date[ ● ], 20[ ● ] Xxxxx Xxxxxxx & Co. 000 Xxxxxxxx Xxxx Xxxxxxxxxxx, XX 00000 Sir: The undersigned, the duly qualified and elected [●[ ● ], of Catalyst BiosciencesEndologix, Inc., a Delaware corporation (the “Company”), does hereby certify in such capacity and on behalf of the Company, pursuant to Section 3(q) of the Equity Distribution Agreement, dated October 15August 13, 2021 2019 (the “Equity Distribution Agreement”), between the Company and Xxxxx Xxxxxxx & Co., that to the best of the knowledge of the undersigned:

Xxxxxxxx Xxxxxx. Xxxxxxxx@xxx.xxx Xxx Xxxxxx Xxxxxx.Xxxxxx@xxx.xxx Xxx X. Hershey Xxx.Xxxxxxx@xxx.xxx Date: Subject: [●], 20[●] Equity Distribution Agreement – Placement Notice Gentlemen: Pursuant to the terms and subject to the conditions contained in the Equity Distribution Agreement between Catalyst Biosciences, IMV Inc. (the “Company”), and Xxxxx Xxxxxxx & Co. (“Agent”) dated October 15March [●], 2021 2020 (the “Agreement”), the Company hereby requests that Agent sell up to [ [●] shares of the Company’s common stockCommon Shares, no par value $0.001 per share, at a minimum market price of U.S. $[ [●] per share. Sales should begin on the date of this Placement Notice and shall continue until [ [●] /[all shares are sold]. SCHEDULE 2 NOTICE PARTIES Catalyst Biosciences, IMV Inc. Nassim Usman xxxxxx@xxxxxx.xxx Xxxxxx Xxxxx 000 Xxxxxx Xxxxxx xxxxxxx@xxxxxx.xxx Avenue, Suite 19 Dartmouth, Nova Scotia, Canada B3B 2C4 Telephone: +0 (000) 000-0000 Facsimile: +0 (000) 000-0000 Xxxxx Xxxxxxx & Co. Xxxx X. Riley Xxxx.Xxxxx@xxx.xxx Xxxxxxx X. Bassett Xxxxxxx.Xxxxxxx@xxx.xxx Connor X. Xxxxxxxx Xxxxxx.Xxxxxxxx@xxx.xxx Xxx Xxxxxx Xxxxxx.Xxxxxx@xxx.xxx Xxx X. Hershey Xxx.Xxxxxxx@xxx.xxx SCHEDULE 3 FORM OF REPRESENTATION CERTIFICATE PURSUANT TO SECTION 3(q4(o) OF THE AGREEMENT [Date] Xxxxx Xxxxxxx & Co. 000 Xxxxxxxx Xxxx Xxxxxxxxxxx, XX 00000 Sir: The undersigned, the duly qualified and elected [●•], of Catalyst Biosciences, Inc., IMV Inc. a Delaware Canadian corporation (the “Company”), does hereby certify in such capacity and on behalf of the Company, pursuant to Section 3(q4(o) of the Equity Distribution Agreement, dated October 15March 18, 2021 2020 (the “Equity Distribution Agreement”), between the Company and Xxxxx Xxxxxxx & Co., that to the best of the knowledge of the undersigned: