Zalicus Inc. Sample Contracts

September 15, 2004
Combinatorx, Inc • December 10th, 2004 • Delaware
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RECITALS
Registration Rights Agreement • December 10th, 2004 • Combinatorx, Inc • Massachusetts
Exhibit 10.6 THIS WARRANT AND THE SHARES ISSUABLE HEREUNDER HAVE NOT BEEN REGISTERED UNDER THE SECURITIES ACT OF 1933, AS AMENDED, AND MAY NOT BE SOLD, PLEDGED OR OTHERWISE TRANSFERRED WITHOUT AN EFFECTIVE REGISTRATION THEREOF UNDER SUCH ACT OR...
Combinatorx, Inc • December 10th, 2004 • California

THIS WARRANT AND THE SHARES ISSUABLE HEREUNDER HAVE NOT BEEN REGISTERED UNDER THE SECURITIES ACT OF 1933, AS AMENDED, AND MAY NOT BE SOLD, PLEDGED OR OTHERWISE TRANSFERRED WITHOUT AN EFFECTIVE REGISTRATION THEREOF UNDER SUCH ACT OR PURSUANT TO RULE 144 OR AN OPINION OF COUNSEL REASONABLY SATISFACTORY TO THE CORPORATION AND ITS COUNSEL THAT SUCH REGISTRATION IS NOT REQUIRED.

RECITALS
Combinatorx, Inc • March 20th, 2006 • Pharmaceutical preparations
COMMON STOCK
Combinatorx, Inc • February 14th, 2005 • Pharmaceutical preparations • New York
9,600,000 Shares EPIRUS BIOPHARMACEUTICALS, INC. Common Stock, Par Value $0.001 Per Share UNDERWRITING AGREEMENT
Underwriting Agreement • January 30th, 2015 • EPIRUS Biopharmaceuticals, Inc. • Pharmaceutical preparations • New York
Exhibit 10.5 THIS WARRANT AND THE SHARES ISSUABLE HEREUNDER HAVE NOT BEEN REGISTERED UNDER THE SECURITIES ACT OF 1933, AS AMENDED, AND MAY NOT BE SOLD, PLEDGED OR OTHERWISE TRANSFERRED WITHOUT AN EFFECTIVE REGISTRATION THEREOF UNDER SUCH ACT OR...
Combinatorx, Inc • December 10th, 2004 • California

THIS WARRANT CERTIFIES THAT, for good and valuable consideration, the receipt of which is hereby acknowledged, COMERICA BANK - CALIFORNIA or its assignee ("Holder") is entitled to purchase the number of fully paid and nonassessable shares of the class of securities (the "Shares") of the corporation (the "Company") at the initial exercise price per Share (the "Warrant Price") all as set forth above and as adjusted pursuant to Article 2 of this warrant, subject to the provisions and upon the terms and conditions set forth in this warrant. ARTICLE 1. EXERCISE. 1.1 METHOD OF EXERCISE. Holder may exercise this warrant by delivering this warrant and a duly executed Notice of Exercise in substantially the form attached as Appendix 1 to the principal office of the Company. Unless Holder is exercising the conversion right set forth in Section 1.2, Holder shall also deliver to the Company a check for the aggregate Warrant Price for the Shares being purchased. 1.2 CONVERSION RIGHT. In lieu of exe

EXHIBIT 1
Research Agreement • March 20th, 2006 • Combinatorx, Inc • Pharmaceutical preparations
COMMON STOCK
Combinatorx, Inc • November 4th, 2005 • Pharmaceutical preparations • New York
RECITALS
License Agreement • August 19th, 2005 • Combinatorx, Inc • Pharmaceutical preparations • New York
AGREEMENT:
Registration Rights Agreement • August 19th, 2005 • Combinatorx, Inc • Pharmaceutical preparations • New York
5,600,000 Shares COMBINATORX, INCORPORATED Common Stock PLACEMENT AGENT AGREEMENT
Placement Agent Agreement • October 11th, 2007 • Combinatorx, Inc • Pharmaceutical preparations • New York
EPIRUS BIOPHARMACEUTICALS, INC.
Stock Option Agreement • May 8th, 2014 • Zalicus Inc. • Pharmaceutical preparations • Delaware

Unless otherwise defined herein, the terms defined in the 2011 Equity Incentive Plan (the “Plan”) shall have the same defined meanings in this Stock Option Agreement (the “Option Agreement”).

BETWEEN
Research and License Agreement • March 20th, 2006 • Combinatorx, Inc • Pharmaceutical preparations • New York
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Contract
Warrant Agreement • October 3rd, 2014 • EPIRUS Biopharmaceuticals, Inc. • Pharmaceutical preparations • California

THIS WARRANT AND THE SHARES ISSUABLE UPON EXERCISE HEREOF HAVE NOT BEEN REGISTERED UNDER THE SECURITIES ACT OF 1933, AS AMENDED (THE “ACT”), OR ANY STATE SECURITIES LAWS, AND MAY NOT BE SOLD, OFFERED FOR SALE, PLEDGED, OR HYPOTHECATED IN THE ABSENCE OF AN EFFECTIVE REGISTRATION STATEMENT RELATED THERETO OR, SUBJECT TO SECTION 11 HEREOF, AN OPINION OF COUNSEL (WHICH MAY BE COMPANY COUNSEL) REASONABLY SATISFACTORY TO THE COMPANY THAT SUCH REGISTRATION IS NOT REQUIRED UNDER THE ACT, OR ANY APPLICABLE STATE SECURITIES LAWS.

SUBCONTRACT AGREEMENT
Subcontract Agreement • August 19th, 2005 • Combinatorx, Inc • Pharmaceutical preparations

AN SAIC-MANAGED PROGRAM TO SUPPORT THE NINDS, NATIONAL INSTITUTES OF HEALTH (NIH), DEPARTMENT OF HEALTH AND HUMAN SERVICES (HHS)

AGREEMENT OF SUBLEASE
Agreement • December 10th, 2004 • Combinatorx, Inc • Massachusetts
Exhibit 10.38 SUBSCRIPTION AND SHAREHOLDERS AGREEMENT
Subscription and Shareholders Agreement • August 19th, 2005 • Combinatorx, Inc • Pharmaceutical preparations
RECITALS
Founder's Agreement • December 10th, 2004 • Combinatorx, Inc • Massachusetts
(DATE)
Combinatorx, Inc • December 10th, 2004

NEITHER THIS PROMISSORY NOTE NOR THE MASTER SECURITY AGREEMENT TO WHICH THIS NOTE IS TIED HAVE BEEN REGISTERED UNDER THE SECURITIES ACT OF 1933, AS AMENDED. NO SALE OR DISPOSITION MAY BE EFFECTED EXCEPT IN COMPLIANCE WITH RULE 144 UNDER SAID ACT OR WITHOUT AN EFFECTIVE REGISTRATION STATEMENT RELATED THERETO OR AN OPINION OF COUNSEL FOR THE HOLDER, SATISFACTORY TO THE COMPANY, THAT SUCH REGISTRATION IS NOT REQUIRED UNDER THE ACT OR RECEIPT OF A NO-ACTION LETTER FROM THE SECURITIES AND EXCHANGE COMMISSION

INDEMNIFICATION AGREEMENT
Indemnification Agreement • September 16th, 2009 • Combinatorx, Inc • Pharmaceutical preparations • Delaware

This Agreement, made and entered into this day of , 2009 (“Agreement”), by and between CombinatoRx, Incorporated, a Delaware corporation (the “Company”), and (“Indemnitee”):

VOTING AGREEMENT
Voting Agreement • April 16th, 2014 • Zalicus Inc. • Pharmaceutical preparations • Delaware

THIS VOTING AGREEMENT (“Agreement”), dated as of April 15, 2014, is made by and among Zalicus Inc., a Delaware corporation (“Phoenix”), Epirus Biopharmaceuticals, Inc., a Delaware corporation (the “Company”), and the undersigned holder (“Stockholder”) of shares of capital stock (the “Shares”) of the Company.

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