Common use of 3Notices Clause in Contracts

3Notices. Any notices or other communications required or permitted to be given hereunder shall be in writing and shall be deemed to be given (a) when delivered if personally delivered to the party for whom it is intended, (b) when delivered, if sent by electronic mail during normal business hours of the recipient, and if not sent during normal business hours, then on the recipient’s next Business Day, provided no rejection or undeliverable notice is received, (c) three (3) days after having been sent by certified or registered mail, return-receipt requested and postage prepaid, or (d) one (1) Business Day after deposit with a nationally recognized overnight courier, freight prepaid, specifying next business day delivery, with written verification of receipt: (a) If to Parent, addressed as follows: GlycoMimetics, Inc. ▇▇▇▇ ▇▇▇▇▇▇▇ ▇▇▇▇▇▇ ▇▇▇▇▇ ▇▇▇▇▇▇▇▇▇, ▇▇▇▇▇▇▇▇ ▇▇▇▇▇ Attention: ▇▇▇▇▇▇▇▇▇ ▇▇▇▇▇▇▇-▇▇▇▇ Email: ▇▇▇▇▇▇▇▇-▇▇▇▇@▇▇▇▇▇▇▇▇▇▇▇▇▇.▇▇▇ ​ with a copy to (which shall not constitute notice), prior to the Closing: ▇▇▇▇▇▇ ▇▇▇▇▇▇, LLP ▇▇▇▇ ▇▇▇▇▇▇ ▇▇▇▇ ▇▇▇▇▇, ▇▇▇▇▇ ▇▇▇ ▇▇▇▇▇▇▇▇▇, ▇▇ ▇▇▇▇▇ Attention: ▇▇▇▇▇ ▇▇▇▇▇ Email: ▇▇▇▇▇▇@▇▇▇▇▇▇.▇▇▇ with a copy to (which shall not constitute notice), following the Closing: ▇▇▇▇▇▇, ▇▇▇▇ & ▇▇▇▇▇▇▇▇ LLP One Embarcadero Center, ▇▇▇▇▇ ▇▇▇▇ ▇▇▇ ▇▇▇▇▇▇▇▇▇, ▇▇ ▇▇▇▇▇ Attention: ▇▇▇▇ ▇▇▇▇, ▇▇▇▇▇▇▇ ▇▇▇▇▇, ▇▇▇▇▇ ▇▇▇▇▇▇▇ Email: ▇▇▇▇▇@▇▇▇▇▇▇▇▇▇▇.▇▇▇, ▇▇▇▇▇▇@▇▇▇▇▇▇▇▇▇▇.▇▇▇, ▇▇▇▇▇▇▇▇@▇▇▇▇▇▇▇▇▇▇.▇▇▇ (b) If to the Company, addressed as follows: Crescent Biopharma, Inc. ▇▇▇ ▇▇▇▇▇▇▇▇ ▇▇▇▇▇▇, ▇▇▇▇▇▇▇▇ ▇▇, ▇▇▇▇▇ ▇▇▇ ▇▇▇▇▇▇▇, ▇▇▇▇▇▇▇▇▇▇▇▇▇ ▇▇▇▇▇ ​ ​ 4898-3031-6054v.5 Attention: General Counsel Email: ▇▇▇▇▇▇▇.▇▇▇▇▇▇▇@▇▇▇▇▇▇▇▇▇▇▇▇▇▇▇▇▇.▇▇▇ with a copy to (which shall not constitute notice): ▇▇▇▇▇▇, ▇▇▇▇ & ▇▇▇▇▇▇▇▇ LLP One Embarcadero Center, ▇▇▇▇▇ ▇▇▇▇ ▇▇▇ ▇▇▇▇▇▇▇▇▇, ▇▇ ▇▇▇▇▇ Attention: ▇▇▇▇ ▇▇▇▇, ▇▇▇▇▇▇▇ ▇▇▇▇▇, ▇▇▇▇▇ ▇▇▇▇▇▇▇ Email: ▇▇▇▇▇@▇▇▇▇▇▇▇▇▇▇.▇▇▇, ▇▇▇▇▇▇@▇▇▇▇▇▇▇▇▇▇.▇▇▇, ▇▇▇▇▇▇▇▇@▇▇▇▇▇▇▇▇▇▇.▇▇▇ (c) If to any Investor, at its address set forth on Exhibit A or to such e-mail address or address as subsequently modified by written notice given in accordance with this Section ‎8.3. Any Person may change the address to which notices and communications to it are to be addressed by notification as provided for herein.

3Notices. Any notices or All notices, consents, waivers and other communications required or permitted to be given hereunder shall be in writing and shall be deemed to be given effective (a) upon receipt when delivered if personally delivered sent through the mails, registered or certified mail, return receipt requested, postage prepaid, with such receipt to be effective the party for whom it is intendeddate of delivery indicated on the return receipt, (b) upon receipt when delivered, if sent by electronic mail during normal business hours of the recipient, an overnight courier (costs prepaid and if not sent during normal business hours, then on the recipient’s next Business Day, provided no rejection or undeliverable notice is receivedreceipt requested), (c) three (3) days after having been on the date personally delivered to an authorized officer of the party to which sent by certified or registered mail, return-receipt requested and postage prepaid, or (d) one (1) Business Day after deposit on the date transmitted by electronic transmission with a nationally recognized overnight courierconfirmation of receipt, freight prepaid, specifying next business day deliveryin all cases, with written verification of receipt: (a) If a copy emailed to Parentthe recipient at the applicable address, addressed to the recipient as follows: GlycoMimeticsif to the Company, to: Marinus Pharmaceuticals, Inc. ▇▇▇▇ ▇▇▇▇▇▇▇ ▇▇▇▇▇▇ ▇▇5 Radnor Corporate Center ▇▇▇ ▇▇▇▇▇▇▇▇▇, ▇▇▇▇▇▇▇▇ ▇▇▇▇▇ Attention: ▇▇▇▇▇▇▇▇▇ ▇▇▇▇▇▇▇-▇▇▇▇ Email: ▇▇▇▇▇▇▇▇-▇▇▇▇@▇▇▇▇▇▇▇▇▇▇▇▇▇.▇▇▇ ​ with a copy to (which shall not constitute notice), prior to the Closing: ▇▇▇▇▇▇ ▇▇▇▇▇▇, LLP ▇▇▇▇ ▇▇▇▇▇▇ ▇▇▇▇ ▇▇▇▇▇, ▇▇▇▇▇ ▇▇▇ ▇▇▇▇▇▇▇▇▇, ▇▇ ▇▇▇▇▇ Attention: ▇▇▇▇▇ ▇▇▇▇▇ EmailChief Financial Officer E-mail: ▇▇▇▇▇▇@▇▇▇▇▇▇.▇▇▇ with a copy to (which shall not constitute notice), following the Closing: ▇▇▇▇▇▇, ▇▇▇▇ & ▇▇▇▇▇▇▇▇ LLP One Embarcadero Center, ▇▇▇▇▇ ▇▇▇▇ ▇▇▇ ▇▇▇▇▇▇▇▇▇, ▇▇ ▇▇▇▇▇ Attention: ▇▇▇▇ ▇▇▇▇, ▇▇▇▇▇▇▇ ▇▇▇▇▇, ▇▇▇▇▇ ▇▇▇▇▇▇▇ Email: ▇▇▇▇▇@▇▇▇▇▇▇▇▇▇▇.▇▇▇, ▇▇▇▇▇▇@▇▇▇▇▇▇▇▇▇▇.▇▇▇, ▇▇▇▇▇▇▇▇@▇▇▇▇▇▇▇▇▇▇.▇▇▇ (b) If to the Company, addressed as follows: Crescent Biopharma, Inc. ▇▇▇ ▇▇▇▇▇▇▇▇ ▇▇▇▇▇▇, ▇▇▇▇▇▇▇▇ ▇▇, ▇▇▇▇▇ ▇▇▇ ▇▇▇▇▇▇▇, ▇▇▇▇▇▇▇▇▇▇▇▇▇ ▇▇▇▇▇ ​ ​ 4898-3031-6054v.5 Attention: General Counsel Email: ▇▇▇▇▇▇▇.▇▇▇▇▇▇▇@▇▇▇▇▇▇▇▇▇▇▇▇▇▇▇▇▇.▇▇▇ with a copy to (which shall not constitute notice): Marinus Pharmaceuticals, Inc. 5 Radnor Corporate Center ▇▇▇ ▇▇▇▇▇▇▇▇▇▇ ▇▇▇▇, ▇▇▇▇ & ▇▇▇▇▇▇▇▇ LLP One Embarcadero Center, ▇▇▇▇▇ ▇▇▇▇ ▇▇▇ ▇▇▇▇▇▇▇▇▇, ▇▇ ▇▇▇▇▇ Attention: ▇▇▇▇ ▇▇▇▇, ▇▇▇▇▇▇▇ ▇▇▇▇▇, ▇▇▇▇▇ ▇▇▇▇▇▇▇ EmailGeneral Counsel E-mail: ▇▇▇▇▇@▇▇▇▇▇▇▇▇▇▇.▇▇▇, ▇▇▇▇▇▇@▇▇▇▇▇▇▇▇▇▇.▇▇▇, ▇▇▇▇▇▇▇▇@▇▇▇▇▇▇▇▇▇▇▇▇▇.▇▇▇ (c) If ▇ if to any the Investor, at its address set forth on Exhibit A or to such eto: c/o Sagard ▇▇▇ ▇▇▇ ▇▇▇▇▇▇, ▇▇▇▇▇ ▇▇▇▇ ▇▇▇▇▇▇▇, ▇▇ ▇▇▇ ▇▇▇ ▇▇▇▇▇▇ Attention: General Counsel E-mail address or address as subsequently modified mail: ▇▇▇▇▇▇▇▇▇@▇▇▇▇▇▇▇▇▇▇▇▇▇▇.▇▇▇ with a copy (which shall not constitute notice) to: ▇▇▇▇▇, ▇▇▇▇▇, ▇▇▇▇, ▇▇▇▇▇▇, ▇▇▇▇▇▇▇ and ▇▇▇▇▇, P.C. ▇▇▇ ▇▇▇▇▇ ▇▇▇▇▇▇ ▇▇▇ ▇▇▇▇, ▇▇▇ ▇▇▇▇ ▇▇▇▇▇ Attention: ▇▇▇▇▇▇▇ ▇▇▇▇▇▇▇, Esq. Email: ▇▇▇▇▇▇▇▇@▇▇▇▇▇.▇▇▇ Each Party hereto may, by written notice given in accordance with this Section ‎8.3. Any Person may change herewith to the other Party hereto, designate any further or different address to which notices subsequent notices, consents, waivers and other communications to it are to shall be addressed by notification as provided for herein.sent. ​

3Notices. Any notices notice, request, instruction or other communications required document or permitted other communication to be given hereunder by a party hereto shall be in writing and shall be deemed to be have been given (ai) when delivered received if personally delivered to the party for whom it is intendedgiven in person or by courier or a courier service (providing proof of delivery), (bii) when delivered, on the date of transmission if sent by electronic mail during normal business hours of the recipientconfirmed facsimile, and if not sent during normal business hours, then (iii) on the recipient’s next Business Day, provided no rejection or undeliverable notice is received, (c) three (3) days after having been Day if sent by an overnight delivery service (providing proof of delivery), or (iv) five (5) Business Days after being deposited in the U.S. mail, certified or registered mail, return-receipt requested and postage prepaid; provided that with respect to notices delivered to the Stockholders’ Representative, or (d) one (1) Business Day after deposit with a nationally recognized overnight courier, freight prepaid, specifying next business day delivery, with written verification of receiptsuch notices must be delivered solely via confirmed facsimile: (a) If to Parentthe Company, addressed as follows: GlycoMimeticsOn-X Life Technologies Holdings, Inc. ▇▇▇▇ ▇▇▇▇▇▇▇ ▇▇▇▇▇▇ ▇▇▇▇▇ ▇▇▇▇▇▇▇▇▇, ▇▇▇▇▇▇▇▇ ▇▇▇▇▇ Attention: ▇▇▇▇▇▇▇▇▇ ▇▇▇▇▇▇▇-▇▇▇▇ Email: ▇▇▇▇▇▇▇▇-▇▇▇▇@▇▇▇▇▇▇▇▇▇▇▇▇▇.▇▇▇ ​ with a copy to (which shall not constitute notice), prior to the Closing: ▇▇▇▇▇▇ ▇▇▇▇▇▇, LLP ▇▇▇▇ ▇▇▇▇▇▇ ▇▇▇▇ ▇▇▇▇▇, ▇▇▇▇▇ ▇▇▇ ▇▇▇▇▇▇▇▇▇B Austin, ▇▇ ▇▇▇▇▇ Texas 78752 Attention: ▇▇▇▇▇ ▇▇▇▇▇ Email▇, President and Chief Executive Officer Facsimile No.: (▇▇▇) ▇▇▇@-▇▇▇▇▇▇.▇▇▇ with a copy to copies (which shall not constitute notice), following the Closing) to: ▇▇▇▇▇▇, ▇▇▇▇ & ▇▇▇▇▇▇▇▇ LLP One Embarcadero Center, ▇▇▇▇▇ ▇▇▇▇ ▇▇▇ ▇▇▇▇▇▇▇▇▇, ▇▇ ▇▇▇▇▇ Attention: ▇▇▇▇ ▇▇▇▇, ▇▇▇▇▇▇▇ ▇▇▇▇▇, ▇▇▇▇▇ ▇▇▇▇▇▇▇ Email: ▇▇▇▇▇@▇▇▇▇▇▇▇▇▇▇.▇▇▇, ▇▇▇▇▇▇@▇▇▇▇▇▇▇▇▇▇.▇▇▇, ▇▇▇▇▇▇▇▇@▇▇▇▇▇▇▇▇▇▇.▇▇▇ (b) If to the Company, addressed as follows: Crescent Biopharma, Inc. LLP ▇▇▇ ▇▇▇▇▇▇▇▇ ▇▇▇▇▇▇, ▇▇▇▇▇▇▇▇ ▇▇, ▇▇▇▇▇ ▇▇▇ ▇▇▇▇▇▇▇, ▇▇▇▇▇▇▇▇▇▇▇▇▇ ▇▇▇▇▇ ​ ​ 4898-3031-6054v.5 Attention: General Counsel Email: ▇▇▇▇▇▇▇.▇▇▇▇▇▇▇@▇▇▇▇▇▇▇▇▇▇▇▇▇▇▇▇▇.▇▇▇ with a copy to (which shall not constitute notice): ▇▇▇▇▇▇, ▇▇▇▇ & ▇▇▇▇▇▇▇▇ LLP One Embarcadero Center, ▇▇▇▇▇ ▇▇▇▇ ▇▇▇ ▇▇▇▇▇▇▇▇▇, ▇▇ ▇▇▇▇▇ Attention: ▇▇▇▇ ▇▇▇▇, ▇▇▇▇▇▇▇ ▇▇▇▇▇, ▇▇▇▇▇ ▇▇▇▇▇ Attention: J. ▇▇▇▇▇▇▇ Email▇▇▇▇▇, Esq. Facsimile No.: (512) 320‑9292 (b) If to the Stockholders’ Representative, addressed as follows: Fortis Advisors LLC Notice Department Facsimile No.: (▇▇▇) ▇▇▇-▇▇▇▇ with copies (which shall not constitute notice) to: ▇▇▇▇▇@▇▇ ▇▇▇▇▇ LLP ▇▇▇ ▇▇▇▇▇▇▇▇ ▇▇▇.▇▇▇, ▇▇▇▇▇▇@▇ ▇▇▇▇ ▇▇▇▇▇▇▇.▇▇▇, ▇▇▇▇▇ ▇▇▇▇@▇ Attention: J. ▇▇▇▇▇▇▇ ▇▇▇▇▇ Facsimile No.: (512) 320‑9292 (c) If to Parent or Merger Sub, or after the Closing, the Surviving Company, addressed as follows: CryoLife, Inc. ▇▇▇▇ ▇▇▇▇▇▇▇ ▇▇▇▇., NW Kennesaw, GA 30144 Attention:▇▇▇▇ ▇. ▇▇▇▇▇▇▇▇ Facsimile No.: (▇▇▇.) ▇▇▇ -▇▇▇▇ with a copy (cwhich shall not constitute notice) If to any Investorto: ▇▇▇▇▇▇ ▇▇▇▇▇▇▇ ▇▇▇▇▇▇▇▇ & ▇▇▇▇▇▇, at its address set forth on Exhibit A Professional Corporation 900 South Capital of Texas Highway Las Cimas IV, Fifth Floor Austin, Texas 78746 Attention: ▇▇▇▇ ▇. ▇▇▇▇▇▇ Facsimile No.: (▇▇▇) ▇▇▇-▇▇▇▇ or to such e-mail address other individual or address as subsequently modified a party hereto may designate for itself by written notice given in accordance with this Section ‎8.3. Any Person may change the address to which notices and communications to it are to be addressed by notification as provided for hereinherein provided.

3Notices. Any All notices or and other communications required or permitted to be given hereunder or made pursuant to this Agreement shall be in writing signed by the sender and shall be deemed to be duly given (a) when delivered on the date delivered, if personally delivered to the party for whom it is intendeddelivered, (b) when delivered, if on the Business Day after being sent by electronic Federal Express or another recognized overnight mail during normal business hours service which utilizes a written form of the recipient, and if not sent during normal business hours, then on the recipient’s receipt for next day or next Business Day, provided no rejection or undeliverable notice is receivedDay delivery, (c) three (3) days Business Days after having been sent mailing, if mailed by U.S. postage-prepaid certified or registered mail, return-return receipt requested and postage prepaidrequested, in each case addressed to the applicable party at the address set forth below or (d) one (1) upon transmission if sent via e-mail, with an additional copy being sent promptly by Federal Express or another recognized overnight mail service which utilizes a written form of receipt for next day or next Business Day after deposit with delivery; provided that a nationally recognized overnight courier, freight prepaid, specifying next business day delivery, with written verification party may change its address for receiving notice by the proper giving of receipt: (a) notice hereunder: If to ParentSeller, addressed as followsto: GlycoMimeticsInsys Therapeutics, Inc. ▇▇▇ ▇. ▇▇▇▇▇▇ ▇▇▇▇ ▇▇▇▇▇▇▇▇, AZ 85224 Attention: General Counsel with a copy (which shall not constitute notice) to: Weil, Gotshal & ▇▇▇▇▇▇ LLP ▇▇▇ ▇▇▇▇▇ ▇▇▇▇▇▇ ▇▇▇▇▇ ▇▇▇▇▇▇▇▇▇, ▇▇▇▇▇▇▇▇ ▇▇▇▇▇ Attention: ▇▇▇▇▇▇▇▇▇ ▇. ▇▇▇▇▇ ▇▇▇▇▇ ▇▇▇▇▇▇-▇▇▇▇ Email: ▇▇▇▇▇▇▇▇-▇▇▇▇@▇▇▇▇▇▇▇▇▇▇▇▇▇.▇▇▇ ​ with a copy to (which shall not constitute notice), prior to the Closing: ▇▇▇▇▇▇ ▇▇▇▇▇▇, LLP ▇▇▇▇ ▇▇▇▇▇▇ ▇▇▇▇ ▇▇▇▇▇, ▇▇▇▇▇ ▇▇▇ ▇▇▇▇▇▇▇▇▇, ▇▇ ▇▇▇▇▇ Attention: ▇▇▇▇▇ ▇▇▇▇▇ Email: ▇▇▇▇▇▇@▇▇▇▇▇▇.▇▇▇ with a copy to (which shall not constitute notice), following the Closing: ▇▇▇▇▇▇, ▇▇▇▇ & ▇▇▇▇▇▇▇▇ LLP One Embarcadero Center, ▇▇▇▇▇ ▇▇▇▇ ▇▇▇ ▇▇▇▇▇▇▇▇▇, ▇▇ ▇▇▇▇▇ Attention: ▇▇▇▇ ▇▇▇▇, ▇▇▇▇▇▇▇ ▇▇▇▇▇, ▇▇▇▇▇ ▇▇▇▇▇▇▇ Email: ▇▇▇▇▇@▇▇▇▇▇▇▇▇▇▇.▇▇▇, ▇▇▇▇▇▇@▇▇▇▇▇▇▇▇▇▇.▇▇▇, ▇▇▇▇▇▇▇▇@▇▇▇▇▇▇▇▇▇▇.▇▇▇ (b) If ▇ if to the CompanyBuyer, addressed as followsto: Crescent BiopharmaChilion Group Holdings US, Inc. ▇▇▇ ▇▇▇▇▇▇▇▇ ▇▇▇▇▇▇, ▇▇▇▇▇▇▇▇ ▇▇, ▇▇ ▇▇▇▇▇▇ ▇▇▇ ▇▇▇▇▇▇▇, ▇▇▇▇▇▇▇, ▇▇▇ ▇▇▇▇, ▇▇▇▇▇▇ Attention: ▇▇▇▇▇▇▇ ▇▇▇▇▇ ​ ​ 4898-3031-6054v.5 Attention: General Counsel Email: ▇▇▇▇▇▇▇.▇▇▇▇▇▇▇@▇▇▇▇▇▇▇▇▇▇▇▇▇▇▇▇▇.▇▇▇ with a copy to (which shall not constitute notice): ) to: ▇▇▇▇▇▇, ▇▇▇▇ & ▇▇▇▇▇▇▇▇▇ LLP One Embarcadero Center, ▇▇▇▇ ▇. ▇▇▇▇▇ ▇▇., ▇▇▇▇▇ ▇▇▇ ▇▇▇▇▇▇, ▇▇▇, ▇▇ ▇▇▇▇▇ Attention: ▇▇▇▇ ▇▇▇▇, ▇▇▇▇▇▇▇ ▇▇▇▇▇, ▇▇▇▇▇ ▇▇▇▇▇▇▇ Email: ▇▇▇▇▇@▇▇▇▇▇▇▇▇▇▇.▇▇▇, ▇▇▇▇▇▇@▇▇▇▇▇▇▇▇▇▇.▇▇▇, ▇▇▇▇▇▇▇▇@▇▇▇▇▇▇▇▇▇▇.▇▇▇ (c) If to any Investor, at its address set forth on Exhibit A or to such e-mail address or address as subsequently modified by written notice given in accordance with this Section ‎8.3. Any Person may change the address to which notices and communications to it are to be addressed by notification as provided for herein.

3Notices. Any notices or All notices, requests, consents, claims, waivers and other communications required or permitted to be given hereunder shall be in writing and shall be deemed to be given have been given: (ai) when delivered if personally delivered to the party for whom it is intendedby hand (with written confirmation of receipt), (bii) when delivered, received by the addressee if sent by electronic a nationally recognized overnight courier (receipt requested), (iii) on the date sent by facsimile or e-mail of a PDF document (with confirmation of transmission) if sent during normal business hours of the recipient, and on the next Business Day if not sent during after normal business hours, then on hours of the recipient’s next Business Day, provided no rejection or undeliverable notice is received(iv) when received by the addressee if mailed, (c) three (3) days after having been sent by certified or registered mail, return-return receipt requested and requested, postage prepaid, . Such communications must be sent to the respective parties at the following addresses (or (d) one (1) Business Day after deposit at such other address for a party as shall be specified in a notice given in accordance with a nationally recognized overnight courier, freight prepaid, specifying next business day delivery, with written verification of receipt: (a) this Section 9.3): If to Parent, addressed as followsSellers: GlycoMimetics, Midway Gold US Inc. 8▇▇▇ ▇▇▇▇▇ ▇▇▇▇▇▇ ▇▇▇▇▇▇▇ ▇▇▇▇▇▇ ▇▇▇▇▇ ▇▇▇▇▇▇▇▇▇, ▇▇▇▇▇▇▇▇ ▇, ▇▇▇▇▇ Attention▇.▇.▇. Attn: ▇▇▇▇▇J▇▇▇▇ ▇▇▇▇▇▇▇-▇▇▇▇ , General Counsel Email: ▇▇▇▇▇▇▇▇-▇▇▇▇@▇▇▇▇▇▇▇▇▇▇▇▇▇.▇▇▇ ​ with a copy to (which shall not constitute notice), prior to the Closing: ▇▇▇▇▇▇ ▇▇▇▇▇▇, LLP ▇▇▇▇ ▇▇▇▇▇▇ ▇▇▇▇ ▇▇▇▇▇, ▇▇▇▇▇ ▇▇▇ ▇▇▇▇▇▇▇▇▇, ▇▇ ▇▇▇▇▇ Attention: ▇▇▇▇▇ ▇▇▇▇▇ Email: ▇▇▇▇▇▇@▇▇▇▇▇▇.▇▇▇ with a copy to (which shall not constitute notice), following the Closing: ▇▇▇▇▇▇, ▇▇▇▇ & ▇▇▇▇▇▇▇▇ LLP One Embarcadero Center, ▇▇▇▇▇ ▇▇▇▇ ▇▇▇ ▇▇▇▇▇▇▇▇▇, ▇▇ ▇▇▇▇▇ Attention: ▇▇▇▇ ▇▇▇▇, ▇▇▇▇▇▇▇ ▇▇▇▇▇, ▇▇▇▇▇ ▇▇▇▇▇▇▇ Email: ▇▇▇▇▇@▇▇▇▇▇▇▇▇▇▇.▇▇▇, ▇▇▇▇▇▇@▇▇▇▇▇▇▇▇▇▇.▇▇▇, j▇▇▇▇▇▇▇▇@▇▇▇▇▇▇▇▇▇▇.▇▇▇ Fax: (▇ ▇▇) ▇▇▇-▇▇▇▇ with a copy to: Squire P▇▇▇▇▇ B▇▇▇▇ (bUS) LLP 2▇▇ ▇. ▇▇▇▇▇▇ ▇▇▇▇▇▇ ▇▇▇▇▇ ▇▇▇▇ ▇▇▇▇▇▇▇▇▇▇, ▇▇ ▇▇▇▇▇ ▇.▇.▇. Attention: S▇▇▇▇▇▇ ▇. ▇▇▇▇▇▇ Email: s▇▇▇▇▇▇.▇▇▇▇▇▇@▇▇▇▇▇▇▇▇.▇▇▇ Fax: 5▇▇-▇▇▇-▇▇▇▇ If to the CompanyBuyer: Solidus Resources, addressed as follows: Crescent Biopharma, Inc. ▇LLC c/o Elko Mining Group LLC 9▇▇ ▇▇▇▇▇▇▇▇ ▇▇▇▇▇▇, ▇▇▇▇▇▇ ▇▇▇ ▇▇▇▇, ▇▇▇▇▇▇ ▇▇▇▇▇ U.S.A. Attn: J▇▇▇ ▇▇▇▇▇▇▇, ▇▇▇▇▇▇▇▇▇▇▇▇▇ ▇▇▇▇▇ ​ ​ 4898-3031-6054v.5 Attention: General Counsel President Email: ▇▇▇▇j▇▇▇.▇▇▇▇▇▇▇@▇▇▇▇▇▇▇▇▇▇▇▇▇▇▇.▇▇.▇ Fax: 7▇▇-▇▇▇-▇▇▇▇ with a copy to (which shall not constitute notice): ▇▇▇▇▇▇to: Waterton Precious Metals Fund II Cayman, ▇▇▇▇ & ▇▇▇▇▇▇▇▇ LLP One Embarcadero CenterLP c/o Waterton Global Resource Management, ▇▇▇▇▇ ▇▇Inc. Commerce Court West 1▇▇ ▇▇▇ ▇▇▇▇▇▇▇▇▇, ▇▇ ▇▇▇▇▇ Attention: ▇▇▇▇ ▇▇▇▇, ▇▇▇▇▇▇▇ ▇▇▇▇▇, ▇▇▇▇▇ ▇▇▇▇ ▇▇▇▇▇▇▇, ▇▇▇▇▇▇▇, ▇▇▇▇▇▇ ▇▇▇ ▇▇▇ Attention: K▇▇▇▇ ▇▇▇▇, General Counsel Email: ▇k▇▇▇▇@▇▇▇▇▇▇▇▇▇▇▇▇▇▇.▇▇▇ Fax: 4▇▇-▇▇▇-▇▇▇▇ with a copy to: Sidley Austin LLP O▇▇ ▇▇▇▇▇ ▇▇▇▇▇▇▇▇ ▇▇▇▇▇▇▇, ▇▇▇▇▇▇@▇▇ ▇▇▇▇▇ ▇▇▇ Attention: J▇▇▇▇▇▇ ▇▇▇▇▇▇▇▇▇▇.▇▇▇, ▇▇ Email: j▇▇▇▇▇▇▇@▇▇▇▇▇▇.▇▇▇ Fax: 3▇▇-▇▇▇-▇▇▇▇.▇▇▇ (c) If to any Investor, at its address set forth on Exhibit A or to such e-mail address or address as subsequently modified by written notice given in accordance with this Section ‎8.3. Any Person may change the address to which notices and communications to it are to be addressed by notification as provided for herein.

3Notices. Any notices or All notices, consents, waivers and other communications required or permitted to be given hereunder shall be in writing and shall be deemed to be have been duly given (a) when delivered if personally delivered to the party for whom it is intended(i) in person, (bii) when deliveredby facsimile or other electronic means (including email), with affirmative confirmation of receipt, (iii) one Business Day after being sent, if sent by electronic mail during normal business hours of the recipientreputable, and if not sent during normal business hours, then on the recipient’s next Business Day, provided no rejection nationally recognized overnight courier service or undeliverable notice is received, (civ) three (3) days Business Days after having been being mailed, if sent by registered or certified or registered mail, returnpre-paid and return receipt requested and postage prepaidrequested, in each case to the applicable Party at the following addresses (or (d) one (1) Business Day after deposit with at such other address for a nationally recognized overnight courier, freight prepaid, specifying next business day delivery, with written verification of receipt: (a) Party as shall be specified by like notice): If to Parentthe Purchaser or Merger Sub at or prior to the Closing, addressed as followsto: GlycoMimetics, Coeptis Therapeutics Holdings Inc. ▇▇▇▇ ▇▇▇▇▇▇▇ ▇▇▇▇▇▇ ▇▇▇▇▇ ▇▇▇▇▇▇▇▇▇, ▇▇▇▇▇▇▇▇ ▇▇▇▇▇ Attention: ▇▇▇▇▇▇▇▇▇ ▇▇▇▇▇▇▇-▇▇▇▇ Email: ▇▇▇▇▇▇▇▇-▇▇▇▇@▇▇▇▇▇▇▇▇▇▇▇▇▇.▇▇▇ ​ with a copy to (which shall not constitute notice), prior to the Closing: ▇▇▇▇▇▇ ▇▇▇▇▇▇, LLP ▇▇▇▇ ▇▇▇▇▇▇ ▇▇▇▇ ▇▇▇▇▇, ▇▇▇▇▇ ▇▇▇ ▇▇▇▇▇▇▇▇▇, ▇▇ ▇▇▇▇▇ AttentionAttn: ▇▇▇▇▇ ▇▇▇▇▇ Email: ▇▇▇▇▇▇@▇▇▇▇▇▇.▇▇▇ with a copy to (which shall not constitute notice), following the Closing: ▇▇▇▇▇▇, ▇▇▇▇ & ▇▇▇▇▇▇▇▇ LLP One Embarcadero Center, ▇▇▇▇▇ ▇▇▇▇ ▇▇▇ ▇▇▇▇▇▇▇▇▇, ▇▇ ▇▇▇▇▇ AttentionCEO Telephone No.: ▇▇▇▇ -▇▇▇▇, ▇▇▇▇▇▇▇ ▇▇▇▇▇, ▇▇▇▇▇ ▇▇▇-▇▇▇▇ Email: ▇▇▇▇▇@▇▇▇▇▇▇▇▇▇▇.▇▇▇, ▇▇▇▇▇▇@▇▇▇▇▇▇▇▇▇▇.▇▇▇, ▇▇▇▇▇▇▇▇@▇▇▇▇▇▇▇▇▇▇.▇▇▇ with a copy (which will not constitute notice) to: ▇ (b) If to the Company, addressed as follows: Crescent Biopharma, Inc. ▇▇▇▇▇▇ ▇▇▇▇▇▇ & ▇▇▇▇ PLLC ▇▇▇ ▇▇▇▇ ▇▇▇▇▇▇, ▇▇▇▇▇▇▇▇ ▇▇, ▇▇▇▇▇ ▇▇▇ ▇▇▇▇, ▇▇▇ ▇▇▇, ▇ ▇▇▇▇▇ Attn: ▇▇▇▇▇ ▇. ▇▇▇▇▇▇▇▇, Esq. Facsimile No.: (▇▇▇) ▇▇▇-▇▇▇▇ Telephone No.: (▇▇▇) ▇▇▇-▇▇▇▇ Email: ▇▇▇@▇▇▇-▇▇▇.▇▇▇ If to the Company or the Surviving Corporation, to: Z Squared Inc. ▇▇▇ ▇▇ ▇▇▇▇▇ ▇▇▇▇▇ ​ ​ 4898-3031-6054v.5 Attention: General Counsel Email: ▇▇▇▇▇▇▇.▇▇▇▇▇▇▇@▇▇▇▇▇▇▇▇▇▇▇▇▇▇▇▇▇.▇▇▇ with a copy to (which shall not constitute notice): ▇▇▇▇▇▇, ▇▇▇▇ & ▇▇▇▇▇▇▇▇ LLP One Embarcadero Center, ▇▇▇▇▇ ▇▇▇▇ ▇▇▇ ▇▇▇▇▇▇▇▇▇, ▇▇ ▇▇▇▇▇ AttentionAttn: ▇▇▇▇ ▇▇▇▇, ▇▇▇▇▇▇▇ ▇▇▇▇▇, ▇ Telephone No.: (▇▇▇▇▇ ) ▇▇▇-▇▇▇▇ Email: ▇▇▇▇▇@▇▇▇▇▇.▇▇▇ with a copy (which will not constitute notice) to: ▇▇▇▇▇ ▇▇▇▇▇.▇▇▇▇ ▇▇▇ ▇▇▇▇ ▇▇▇▇▇▇, ▇▇▇▇▇ ▇▇@▇▇ ▇▇▇▇▇▇▇, ▇▇▇.▇▇ ▇▇▇, ▇▇ Attn: ▇▇▇▇ ▇▇▇▇▇ ▇▇. (“JR”) Telephone No.: (▇▇▇) ▇▇▇-▇▇▇▇ Email: ▇▇▇▇▇▇▇@▇▇▇▇▇▇▇▇▇▇.▇▇▇ (c) If to any Investor, at its address set forth on Exhibit A or to such e-mail address or address as subsequently modified by written notice given in accordance with this Section ‎8.3. Any Person may change the address to which notices and communications to it are to be addressed by notification as provided for herein.

3Notices. Any notices All notices, demands, requests, consents, approvals, or other communications (collectively, “Notices” ) required or permitted to be given hereunder or which are given with respect to this Agreement shall be in writing and shall be personally served, delivered by reputable air courier service with charges prepaid, or transmitted by hand delivery, telegram, telex, or facsimile, addressed as set forth below, or to such other address as such party shall have specified most recently by written notice. Notice shall be deemed to be given (a) when delivered on the date of service or transmission if personally delivered to the party for whom it served or transmitted by telegram, telex, or facsimile; provided, that if such service or transmission is intended, (b) when delivered, if sent by electronic mail during normal not on a business hours of the recipient, and if not sent during day or is after normal business hours, then such notice shall be deemed given on the recipient’s next Business Day, business day. Notice otherwise sent as provided no rejection or undeliverable notice is received, (c) three (3) days after having been sent by certified or registered mail, return-receipt requested and postage prepaid, or (d) one (1) Business Day after deposit with a nationally recognized overnight courier, freight prepaid, specifying herein shall be deemed given on the next business day following timely delivery of such notice to a reputable air courier service with an order for next-day delivery, with written verification of receipt: (a) If to Parent, addressed as follows. ​ To the Company before the Closing: GlycoMimetics, Inc. ​ DiamondHead Holdings Corp. ▇▇▇ ▇▇▇▇ ▇▇▇., ▇▇▇ Floor New York, New York 10177 Attention: ▇▇▇▇▇ ▇. ▇▇▇▇▇▇▇▇ ▇▇▇▇▇ ▇▇▇▇▇▇▇▇▇, ▇▇▇▇▇▇▇▇ ▇▇▇▇▇ Attention: ▇▇▇▇▇▇▇▇▇ ▇▇▇▇▇▇▇-▇▇▇▇ Email: ▇▇▇▇▇▇▇▇-▇▇▇▇@▇▇▇▇▇▇▇▇▇▇▇▇▇.▇▇▇ ​ with a copy to (which shall not constitute notice), prior to the Closing: ▇▇▇▇▇▇ ▇▇▇▇▇▇, LLP ▇▇▇▇ ▇▇▇▇▇▇ ▇▇▇▇ ▇▇▇▇▇, ▇▇▇▇▇ ▇▇▇ ▇▇▇▇▇▇▇▇▇, ▇▇ ▇▇▇▇▇ Attention: ▇▇▇▇▇ ▇▇▇▇▇ Email: ▇▇▇▇▇▇@▇▇▇▇▇▇.▇▇▇ with a copy to (which shall not constitute notice), following the Closing: ▇▇▇▇▇▇, ▇▇▇▇ & ▇▇▇▇▇▇▇▇ LLP One Embarcadero Center, ▇▇▇▇▇ ▇▇▇▇ ▇▇▇ ▇▇▇▇▇▇▇▇▇, ▇▇ ▇▇▇▇▇ Attention: ▇▇▇▇ ▇▇▇▇, ▇▇▇▇▇▇▇ ▇▇▇▇▇, ▇▇▇▇▇ ▇▇▇▇▇▇▇ Email: ▇▇▇▇▇@▇▇▇▇▇▇▇▇▇▇.▇▇▇, ▇▇▇▇▇▇@▇▇▇▇▇▇▇▇▇▇.▇▇▇, ▇▇▇▇▇▇▇▇@▇▇▇▇▇▇▇▇▇▇.▇▇▇ (b) If to the Company, addressed as follows: Crescent Biopharma, Inc. ▇▇▇ ▇▇▇▇▇▇▇▇ ▇▇▇▇▇▇, ▇▇▇▇▇▇▇▇ ▇▇, ▇▇▇▇▇ ▇▇▇ ▇▇▇▇▇▇▇, ▇▇▇▇▇▇▇▇▇▇▇▇▇ ▇▇▇▇▇ ​ ​ 4898-3031-6054v.5 Attention: General Counsel Email: ▇▇▇▇▇▇▇.▇▇▇▇▇▇▇@▇▇▇▇▇▇▇▇▇▇▇▇▇▇▇▇▇.▇▇▇ with a copy to (which shall not constitute notice): ▇▇▇▇▇▇, ▇▇▇▇ & ▇▇▇▇▇▇▇▇ LLP One Embarcadero Center, ▇▇▇▇▇ ▇▇▇▇ ▇▇▇ ▇▇▇▇▇▇▇▇▇, ▇▇ ▇▇▇▇▇ Attention: ▇▇▇▇ ▇▇▇▇, ▇▇▇▇▇▇▇ ▇▇▇▇▇, ▇▇▇▇▇ ▇▇▇▇▇▇▇ Email: ▇▇▇▇▇@▇▇▇▇▇▇▇▇▇▇.▇▇▇, ; ▇▇▇▇▇▇▇@▇▇▇▇▇▇▇▇▇▇▇▇▇▇▇▇▇▇▇.▇▇▇ ​ ​ with a copy to: ​ ▇▇▇▇▇▇▇▇ & ▇▇▇▇▇▇▇▇ LLP ▇▇▇ ▇▇▇▇▇ ▇▇▇▇▇▇ New York, New York 10004 Attention: ▇▇▇▇▇▇ ▇▇▇▇▇▇ ▇▇▇▇▇ ▇▇▇▇▇ E-mail: ▇▇▇▇▇▇▇@▇▇▇▇▇▇▇▇.▇▇▇ ▇▇▇▇▇▇@▇▇▇▇▇▇▇▇.▇▇▇ ​ To the Company after the Closing: ​ Great Southern Homes, Inc. ▇▇▇ ▇▇▇▇▇ ▇▇▇▇▇ ▇▇▇▇▇ Irmo, South Carolina 29063 Attention: ▇▇▇ ▇’▇▇▇▇▇, Chief Administrative Officer ▇▇▇▇▇ ▇▇▇▇▇▇, Executive Vice President and General Counsel Email: ▇▇▇▇▇▇▇▇▇@▇▇▇▇▇▇▇▇▇▇▇▇▇▇▇▇▇▇.▇▇▇ ▇▇▇▇▇▇▇▇▇▇▇@▇▇▇▇▇▇▇▇▇▇▇▇▇▇▇▇▇▇.▇▇▇ ​ with a copy to: ​ ▇▇▇▇▇▇ ▇▇▇▇▇▇▇ ▇▇▇▇▇ & ▇▇▇▇▇▇▇▇▇▇▇ LLP ▇▇▇ ▇▇▇▇▇▇▇▇▇▇▇▇ ▇▇▇▇▇▇, ▇▇, ▇▇▇▇▇ ▇▇▇ Washington, D.C., 20001 Attention: ▇▇▇▇▇▇ ▇. ▇▇▇▇▇▇ ▇▇▇▇ ▇▇▇▇▇▇ ▇▇▇▇▇▇▇▇ Email: ▇▇▇▇.▇▇▇ (c) If ▇▇▇@▇▇▇▇▇▇▇▇▇▇▇▇▇.▇▇▇ ▇▇▇▇.▇▇▇▇▇▇▇▇▇▇▇▇▇▇@▇▇▇▇▇▇▇▇▇▇▇▇▇.▇▇▇ ​ To a Holder, to any Investor, at its the address set forth below such ▇▇▇▇▇▇’s name on Exhibit A or to such e-mail address or address as subsequently modified by written notice given in accordance with this Section ‎8.3hereto. Any Person may change the address to which notices and communications to it are to be addressed by notification as provided for herein.​