Common use of AGREEMENT AND MODIFICATION Clause in Contracts

AGREEMENT AND MODIFICATION. Order of Precedence Should there be any inconsistency between the Protocol and the terms of this Agreement, or any other document incorporated herein, the terms of the Protocol shall prevail to the extent of any inconsistency except insofar as the inconsistency relates to Clauses 5, 6, 7, 8, 10, 11 and 16 of this Agreement, whereby the terms of this Agreement shall prevail. Any change in the terms of this Agreement shall be valid only if the change is made in writing, agreed and signed by the Parties. Any amendment to the Protocol (‘Protocol Amendment’) shall be managed by means of the change control procedure set out in this Clause. For the purposes of this Agreement, a ‘change request’ is a request to change the obligations of the Parties arising from a Protocol Amendment. Where the Sponsor or CRO originates a change request, the Participating Organisation shall provide the Sponsor or CRO, within fourteen (14) days of receiving the change request, details of the impact that the proposed Protocol Amendment will have upon the costs of carrying out the Non-Interventional Study and the other terms of this Agreement. A change request shall become a ‘change order’ when the requirements of the change control procedure have been satisfied and any necessary change to this Agreement is signed by the authorised representatives of all Parties. An amended financial appendix shall be signed and appended to this Agreement according to Clause 12.2 above. This Agreement contains the entire understanding between the Parties and supersedes all other agreements (other than the agreement contracting the CRO to work on behalf of the Sponsor with regards to this Non-Interventional Study), negotiations, representations and undertakings, whether written or oral, of prior date between the Parties relating to the Non-Interventional Study that is the subject of this Agreement.

AGREEMENT AND MODIFICATION. Order of Precedence Should there be any inconsistency between the Protocol and the terms of this Agreement, or any other document incorporated herein, the terms of the Protocol shall prevail to the extent of any inconsistency except insofar as the inconsistency relates to Clauses 5, 6, 7, 8, 10, 11 and 16 of this Agreement, whereby the terms of this Agreement shall prevail. Any change in the terms of this Agreement shall be valid only if the change variation is made in writing, agreed and signed by the Parties. Any amendment to the Protocol (‘“Protocol Amendment’”) shall be managed by means of the change control procedure set out in this Clause. For the purposes of this Agreement, a ‘change request’ “Change Request” is a request to change the obligations of the Parties arising from a Protocol Amendment. Where the Sponsor or CRO originates a change requestChange Request, the Participating Organisation shall provide the Sponsor or CRO, within fourteen (14) days of receiving the change requestChange Request, details of the impact that the proposed Protocol Amendment will have upon the costs of carrying out the Non-Interventional Study and the other terms of this Agreement. A change request Change Request shall become a ‘change order’ “Change Order” when the requirements of the change control procedure have been satisfied and any necessary change to this Agreement is signed by the authorised representatives of all Parties. An amended financial appendix shall be signed and appended to this Agreement according to Clause 12.2 above. This Agreement contains the entire understanding between the Parties and supersedes all other agreements (other than the agreement contracting the CRO to work on behalf of the Sponsor with regards to this Non-Interventional Study), negotiations, representations and undertakings, whether written or oral, of prior date between the Parties relating to the Non-Interventional Study that is the subject of this Agreement.

AGREEMENT AND MODIFICATION. Order of Precedence Should there be any inconsistency between the Protocol and the terms of this Agreement, Agreement or any other document incorporated herein, the terms of the Protocol shall prevail to the extent of any inconsistency except insofar as the inconsistency relates to Clauses 5, 6, 7, 8, 10, 11 and 16 of this Agreement, whereby the terms of this Agreement shall prevail. Any change in the terms of this Agreement shall be valid only if the change is made in writing, agreed and signed by the Parties. Any amendment to the Protocol (‘Protocol Amendment’) shall be managed by means of the change control procedure set out in this Clause. For the purposes of this Agreement, a ‘change request’ is a request to change the obligations of the Parties arising from a Protocol Amendment. Where the Sponsor or CRO originates a change request, the Participating Organisation shall provide the Sponsor or CROSponsor, within fourteen (14) days of receiving the change request, details of the impact that the proposed Protocol Amendment will have upon the costs of carrying out the Non-Interventional Study and the other terms of this Agreement. A change request shall become a ‘change order’ when the requirements of the change control procedure have been satisfied and any necessary change to this Agreement is signed by the authorised representatives of all the Parties. An amended financial appendix shall be signed and appended to this Agreement according to Clause 12.2 above. This Agreement contains the entire understanding between the Parties and supersedes all other agreements (other than the agreement contracting the CRO to work on behalf of the Sponsor with regards to this Non-Interventional Study)agreements, negotiations, representations and undertakings, whether written or oral, of prior date between the Parties relating to the Non-Interventional Study that is the subject of this Agreement.

AGREEMENT AND MODIFICATION. Order of Precedence Should there be any inconsistency between the Protocol and the terms of this Agreement, or any other document incorporated herein, the terms of the Protocol shall prevail to the extent of any inconsistency except insofar as the inconsistency relates to Clauses 5, 6, 7, 8, 10, 11 and 16 of this Agreement, whereby the terms of this Agreement shall prevail. Any change in the terms of this Agreement shall be valid only if the change is made in writing, agreed and signed by the Parties. Any amendment to the Protocol (‘“Protocol Amendment’”) shall be managed by means of the change control procedure set out in this Clause. For the purposes of this Agreement, a ‘“change request’ ” is a request to change the obligations of the Parties arising from a Protocol Amendment. Where the Sponsor or CRO originates a change request, the Participating Organisation shall provide the Sponsor or CRO, within fourteen (14) days of receiving the change request, details of the impact that the proposed Protocol Amendment will have upon the costs of carrying out the Non-Interventional Study Clinical Trial and the other terms of this Agreement. A change request shall become a ‘“change order’ ” when the requirements of the change control procedure have been satisfied and any necessary change to this Agreement is signed by the authorised representatives of all Parties. An amended financial appendix shall be signed and appended to this Agreement according to Clause 12.2 above. This Agreement contains the entire understanding between the Parties and supersedes all other agreements (other than the agreement contracting the CRO to work on behalf of the Sponsor with regards to this Non-Interventional StudyClinical Trial), negotiations, representations and undertakings, whether written or oral, of prior date between the Parties relating to the Non-Interventional Study Clinical Trial that is the subject of this Agreement.