CBBCT for Breast Imaging System Sample Clauses

CBBCT for Breast Imaging System. The CBBCT system employs a horizontally oriented gantry beneath a subject support table, which incorporates an x-ray tube with a 0.3 mm focal spot at one end and a high-resolution, 40 x 30 cm real- time flat panel detector (FPD) at the opposite end. The extensive detector dynamic range (>16 bit) along with the 3D imaging technique provides up to 30x greater contrast resolution than standard imaging. The system is designed and built in compliance with the national and international safety standards for medical equipment. For a CBBCT scan, the subject lies prone on the support table. The breast of interest is placed through the opening in the table and the breast is positioned in the imaging field. The table sits above a motorized scanning arm carrying an x-ray source and image detector that allows a 360° rotational x- ray sequence in ~10 seconds. To acquire the 10 second, full-volume scan of the breast, the CBBCT gantry rotates 360o around the subject’s breast, acquiring 300 pulsed projection images at ~8 ms each. Acquired image data is sent to a computer to perform 3D reconstruction. Specialized 3D visualization software constructs a three-dimensional model of the breast from the images taken during the rotational x-ray sequence. Once the data is reconstructed, it provides the radiologist with (0.27 mm)3 (standard resolution) cross-sectional slice data displayed in any plane as well as a 3D rendering. The data set can be reconstructed to (0.155 mm)3 with a sharp ramp filter for high resolution volume of interest (especially for calcifications) without having to re-scan the subject. Our previous studies to-date has illustrated the capacity of the non-contrast CBBCT to image the breast without structure overlap and with superior contrast resolution as compared with standard breast imaging. The study results illustrate that the CBBCT system is able to image the entire breast from axillary region to chest wall with clinically acceptable image quality and radiation dose comparable to conventional mammography. Cancers are better visualized as well as defined. In general, it is observed, that cancerous tissues absorb more x-rays than normal tissues, as determined by a higher Hounsfield unit, (CT number or x-ray attenuation coefficient), but the CT number of some benign entities can match that of cancer.
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