CENTRAL NERVOUS SYSTEM ABNORMALITIES Sample Clauses

CENTRAL NERVOUS SYSTEM ABNORMALITIES. Seizures have been reported in 15-25% of KS patients (▇▇▇▇▇ et al. 2003, ▇▇▇▇▇▇ et al. 2003, ▇▇▇▇▇▇▇ et al. 2004, ▇▇▇ et al. 2007) often due to structural brain anomalies. Central nervous system abnormalities described include ▇▇▇▇▇▇ ▇▇▇▇▇▇ I malformation, syringohydromyelia, cerebellar vermis cleft (▇▇▇▇▇-▇▇▇▇▇▇ variant), absence of corpus callosum and cortical atrophy (▇▇▇ et al. 1997, ▇▇▇-▇▇▇▇▇ and ▇▇▇▇▇ 2005, ▇▇▇▇ et al. 2006), hydrocephalus with ventricular enlargement (▇▇▇▇▇▇ et al. 1990), hydrocephalus caused by aqua ductal stenosis (Kasuya et al. 1998), cortical and central hypoplasia, atrophy of the hippocampus and periventricular changes (▇▇▇▇▇▇▇ et al. 2004), periventricular nodular heterotopia (▇▇▇▇▇ et al. 2002), polymicrogyria (▇▇ ▇▇▇▇▇▇▇ et al. 1999, ▇▇▇▇▇▇ et al. 2003), subarachnoid cysts (▇▇▇ et al. 1997), and microcephaly (▇▇ et al. 2011). Neonatal hypotonia and isolated cranial nerve palsies have been also described (▇▇▇▇▇▇▇▇▇ and ▇▇▇▇▇▇▇ 2003).