CENTRAL NERVOUS SYSTEM ABNORMALITIES Sample Clauses

CENTRAL NERVOUS SYSTEM ABNORMALITIES. Seizures have been reported in 15-25% of KS patients (Xxxxx et al. 2003, Xxxxxx et al. 2003, Xxxxxxx et al. 2004, Xxx et al. 2007) often due to structural brain anomalies. Central nervous system abnormalities described include Xxxxxx Xxxxxx I malformation, syringohydromyelia, cerebellar vermis cleft (Xxxxx-Xxxxxx variant), absence of corpus callosum and cortical atrophy (Xxx et al. 1997, Xxx-Xxxxx and Xxxxx 2005, Xxxx et al. 2006), hydrocephalus with ventricular enlargement (Xxxxxx et al. 1990), hydrocephalus caused by aqua ductal stenosis (Kasuya et al. 1998), cortical and central hypoplasia, atrophy of the hippocampus and periventricular changes (Xxxxxxx et al. 2004), periventricular nodular heterotopia (Xxxxx et al. 2002), polymicrogyria (Xx Xxxxxxx et al. 1999, Xxxxxx et al. 2003), subarachnoid cysts (Xxx et al. 1997), and microcephaly (Xx et al. 2011). Neonatal hypotonia and isolated cranial nerve palsies have been also described (Xxxxxxxxx and Xxxxxxx 2003).
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