Choice of erosive agent Sample Clauses

Choice of erosive agent. The choice of erosive agent varies according to the aim of the study. For modelling erosion from extrinsic sources of acid, the options are either a commercially available product, such as carbonated soft drinks and fruit juices, or a laboratory made acid solution, most commonly citric or phosphoric acids (Eisenburger et al., 2001a) although malic, lactic, tartaric, oxalic and acetic acids have also been used (Xxxxxx et al., 2005). Previous authors have also modelled erosion with wine (Xxxxxxxxxxxxx et al., 2009) and other alcoholic beverages (Lissera et al., 1998), acidic medicines, lozenges (Lussi et al., 1997) and snack foods (Xxxxx et al., 1997). The advantages of a commercially available product are that there is a degree of verisimilitude to the clinical situation, however due to variations in geographical and market availability of products this introduces the possibility that repeating a previously published experiment may be complicated by a manufacturer changing the formulation of a product or even due to simple variations in batches of a product. Laboratory made acid solutions are easily reproducible, inexpensive and can be precisely formulated to produce repeatable results. For studies modelling erosion due to intrinsic sources of acid, a solution of HCL is most commonly used (Holme et al., 2005) however gastric juice has also been used (Xxxxxxxx and Coward, 2001).