Common use of Counterparts; Further Instruments Clause in Contracts

Counterparts; Further Instruments. This Agreement may be executed in two or more counterparts, each of which shall be deemed an original, but all of which together shall constitute one and the same instrument. The parties hereto agree to execute such further instruments and to take such further action as may be reasonably necessary to carry out the purposes and intent of this Agreement. [Signatures of the Corporation and the Participant follow on Schedule A/Grant Notice.] TARGACEPT, INC. 2006 STOCK INCENTIVE PLAN Nonqualified Stock Option Agreement (Nonemployee Directors)

Counterparts; Further Instruments. This Agreement may be executed in two or more counterparts, each of which shall be deemed an original, but all of which together shall constitute one and the same instrument. The parties hereto agree to execute such further instruments and to take such further action as may be reasonably necessary to carry out the purposes and intent of this Agreement. [Signatures of the Corporation and the Participant follow on Schedule A/Grant Notice.] TARGACEPTSPINEMEDICA CORP. 2005 EMPLOYEE, INC. 2006 DIRECTOR AND CONSULTANT STOCK INCENTIVE PLAN Nonqualified Incentive Stock Option Agreement (Nonemployee DirectorsEmployees)

Counterparts; Further Instruments. This Agreement may be executed in two or more counterparts, each of which shall be deemed an original, but all of which together shall constitute one and the same instrument. The parties hereto agree to execute such further instruments and to take such further action as may be reasonably necessary to carry out the purposes and intent of this Agreement. [Signatures of the Corporation and the Participant follow on Schedule A/Grant Notice.] TARGACEPT, INC. 2006 2005 STOCK INCENTIVE PLAN Nonqualified Stock Option Agreement (Nonemployee Directors)

Counterparts; Further Instruments. This Agreement may be executed in two or more counterparts, each of which shall be deemed an original, but all of which together shall constitute one and the same instrument. The parties hereto agree to execute such further instruments and to take such further action as may be reasonably necessary to carry out the purposes and intent of this Agreement. [Signatures of the Corporation and the Participant follow on Schedule A/Grant Notice.] TARGACEPTXXXXXXX & XXXXXXX, INCLTD. 2006 1997 OMNIBUS STOCK INCENTIVE PLAN Independent Contractor Nonqualified Stock Option Agreement (Nonemployee Directors)Agreement

Counterparts; Further Instruments. This Agreement may be executed in two or more counterparts, each of which shall be deemed an original, but all of which together shall constitute one and the same instrument. The parties hereto agree to execute such further instruments and to take such further action as may be reasonably necessary to carry out the purposes and intent of this Agreement. [Signatures of the Corporation and the Participant follow on Schedule A/Grant Notice.] TARGACEPT, INCSPINEMEDICA CORP. 2006 2007 STOCK INCENTIVE PLAN Nonqualified Stock Option Agreement (Nonemployee DirectorsNon-employee Directors and Independent Contractors)

Counterparts; Further Instruments. This Agreement may be executed in two or more counterparts, each of which shall be deemed an original, original but all of which together shall constitute one and the same instrument. The parties hereto agree to execute such further instruments and to take such further action as may be reasonably necessary to carry out the purposes and intent of this Agreement. [Signatures of the Corporation and the Participant follow on Schedule A/Grant Notice.] TARGACEPTMIMEDX, INC. 2006 STOCK INCENTIVE PLAN Nonqualified Stock Option Agreement (Nonemployee Directors)Non-employee Directors and Independent Contractors) Schedule A/Grant Notice

Counterparts; Further Instruments. This Agreement may be executed in two or more counterparts, each of which shall be deemed an original, but all of which together shall constitute one and the same instrument. The parties hereto agree to execute such further instruments and to take such further action as may be reasonably necessary to carry out the purposes and intent of this Agreement. [Signatures of the Corporation and the Participant follow on Schedule A/Grant Notice.] TARGACEPT, INC. 2006 STOCK INCENTIVE PLAN Nonqualified Stock Option Agreement (Nonemployee DirectorsEmployees)

Counterparts; Further Instruments. This Agreement may be executed in two or more counterparts, each of which shall be deemed an original, but all of which together shall constitute one and the same instrument. The parties hereto agree to execute such further instruments and to take such further action as may be reasonably necessary to carry out the purposes and intent of this Agreement. [Signatures of the Corporation and the Participant follow on Schedule A/Grant Notice.] TARGACEPTSPINEMEDICA CORP. 2005 EMPLOYEE, INC. 2006 DIRECTOR AND CONSULTANT STOCK INCENTIVE PLAN Nonqualified Stock Option Agreement (Nonemployee DirectorsNon-employee Directors and Independent Contractors)

Counterparts; Further Instruments. This Agreement may be executed in two or more counterparts, each of which shall be deemed an original, but all of which together shall constitute one and the same instrument. The parties hereto agree to execute such further instruments and to take such further action as may be reasonably necessary to carry out the purposes and intent of this Agreement. [Signatures of the Corporation and the Participant follow on Schedule A/Grant Notice.] TARGACEPTGEOVAX LABS, INC. 2006 2016 STOCK INCENTIVE PLAN Nonqualified Stock Option Agreement (Nonemployee DirectorsDirectors and Independent Contractors)

Counterparts; Further Instruments. This Agreement may be executed in two or more counterparts, each of which shall be deemed an original, but all of which together shall constitute one and the same instrument. The parties hereto agree to execute such further instruments and to take such further action as may be reasonably necessary to carry out the purposes and intent of this Agreement. [Signatures of the Corporation and the Participant follow on Schedule A/Grant Notice.] TARGACEPTXXXXXXX & XXXXXXX, INCLTD. 2006 1997 OMNIBUS STOCK INCENTIVE PLAN Director Nonqualified Stock Option Agreement (Nonemployee Directors)Agreement

Counterparts; Further Instruments. This Agreement may be executed in two or more counterparts, each of which shall be deemed an original, but all of which together shall constitute one and the same instrument. The parties hereto agree to execute such further instruments and to take such further action as may be reasonably necessary to carry out the purposes and intent of this Agreement. [Signatures of the Corporation and the Participant follow on Schedule A/Grant Notice.] TARGACEPT, INCSPINEMEDICA CORP. 2006 2007 STOCK INCENTIVE PLAN Nonqualified Incentive Stock Option Agreement (Nonemployee DirectorsEmployees)

Counterparts; Further Instruments. This Agreement may be executed in two or more counterparts, each of which shall be deemed an original, but all of which together shall constitute one and the same instrument. The parties hereto agree to execute such further instruments and to take such further action as may be reasonably necessary to carry out the purposes and intent of this Agreement. [Signatures of the Corporation and the Participant follow on Schedule A/Grant Notice.] TARGACEPTMIMEDX, INC. 2006 STOCK INCENTIVE PLAN Nonqualified Incentive Stock Option Agreement (Nonemployee DirectorsEmployees)

Counterparts; Further Instruments. This Agreement may be executed in two or more counterparts, each of which shall be deemed an original, but all of which together shall constitute one and the same instrument. The parties hereto agree to execute such further instruments and to take such further action as may be reasonably necessary to carry out the purposes and intent of this Agreement. [Signatures of the Corporation and the Participant follow on Schedule A/Grant Notice.] TARGACEPT, INC. 2006 2005 STOCK INCENTIVE PLAN Nonqualified Stock Option Agreement (Nonemployee DirectorsEmployees)

Counterparts; Further Instruments. This Agreement may be executed in two or more counterparts, each of which shall be deemed an original, but all of which together shall constitute one and the same instrument. The parties hereto agree to execute such further instruments and to take such further action as may be reasonably necessary to carry out the purposes and intent of this Agreement. [Signatures of the Corporation and the Participant follow on Schedule A/Grant Notice.] TARGACEPT, INC. 2006 2005 STOCK INCENTIVE PLAN Nonqualified Incentive Stock Option Agreement (Nonemployee DirectorsEmployees)

Counterparts; Further Instruments. This Agreement may be executed in two or more counterparts, each of which shall be deemed an original, but all of which together shall constitute one and the same instrument. The parties hereto agree to execute such further instruments and to take such further action as may be reasonably necessary to carry out the purposes and intent of this Agreement. [Signatures of the Corporation and the Participant follow on Schedule A/Grant Notice.] TARGACEPT, INC. 2006 STOCK INCENTIVE PLAN Nonqualified Incentive Stock Option Agreement (Nonemployee DirectorsEmployees)