Common use of Defined Terms Section Clause in Contracts

Defined Terms Section. Alliance Manager 3.1 Auditor 10.4(c) Bankruptcy Event 13.5 Bankrupt Party 15.13 Claims 11.1 Clinical Supply Agreement 7.1 Commercialization Plan 6.2(a) Commercial Supply Agreement 7.2(a) Competing Program 15.5(b) Confidentiality Agreement 1.20 DMF 5.1(b) Effective Date Preamble Enforcing Party 9.4(c) Executive Officer 14.1 First Supplemental Development Plan 4.2 GAAP 1.1 Global Development Plan 4.3(d) Global Strategy 4.3(d) Global Territory Expansion Opportunity 6.6 GQP Agreement 5.1(b) ICC 14.2 Indemnified Party 11.3 Indemnifying Party 11.3 Infringement 9.4(a) Infringement Action 9.5 Initial Development Plan 4.2 Initial Purchase Price Payment 8.5(a)(i) JGAAP 1.1 Joint Inventions 9.1(c)(iii) Joint Steering Committee 3.2(a) Kaken Preamble Kaken Housemarks 9.6(b) Kaken Indemnitees 11.1 Kaken Inventions 9.1(c)(ii) Kaken Product Mark 9.6(a) Kaken Sublicense Agreement 2.1(c) Lilly 1.86 Losses 11.1 Defined Terms Section Major Spruce Partner 2.2 Manufacturing Technology Transfer Agreement 7.2(b) NDA 1.56 Non-Bankrupt Party 15.13 Party Preamble Payment 8.9(b) Pharmacovigilance Agreement 5.8 Product Materials 4.6 Reconciliation Amount 8.5(a)(i) Remedial Action 5.9 Right of Reference 5.5 ROFN 6.6 ROFN Exercise Period 6.6 ROFN Exercise Notice 6.6 ROFN Negotiation Period 6.6 ROFN Offer Notice 6.6 Royalty Term 8.4(b) SEC 12.3(c) Spruce Preamble Spruce Indemnitees 11.2 Spruce Inventions 9.1(c)(i) Spruce Partner 2.2 Step-In Rights 9.2(e) Tax Changing Decision 8.9(b) Tax Documents 8.1 Term 13.1 Territory Development Plan 4.2 Territory Expansion Opportunity 6.6 Transfer Price 8.4(a)(i) Working Group 3.5

Defined Terms Section. Alliance Manager 3.1 Auditor 10.4(cExchange Fund 2.2(a) Bankruptcy Event 13.5 Bankrupt Excluded Party 15.13 Claims 11.1 Clinical Supply Agreement 7.1 Commercialization Plan 6.2(a8.13 Excluded Party Termination Fee End Date 8.13 Excluded Shares 2.1(a) Commercial Supply Agreement 7.2(aFCPA 8.13 Financing 4.5(a) Competing Program 15.5(bFinancing Commitments 4.5(a) Confidentiality Agreement 1.20 DMF Financing Sources 8.13 Foreign Subsidiaries 5.1(b) Effective Date Preamble Enforcing Party 9.4(cGAAP 8.13 Governmental Antitrust Entity 8.13 Governmental Entity 8.13 Government Official 8.13 Guarantee 4.7 Guarantor(s) Executive Officer 14.1 First Supplemental Development Plan 4.2 GAAP 1.1 Global Development Plan 4.3(d4.7 Hazardous Substance 8.13 HSR Act 8.13 Indebtedness 8.13 Indemnified Parties 5.11(a) Global Strategy 4.3(d) Global Territory Expansion Opportunity 6.6 GQP Agreement 5.1(b) ICC 14.2 Indemnified Party 11.3 Indemnifying Party 11.3 Infringement 9.4(a) Infringement Action 9.5 Initial Development Plan 4.2 Initial Purchase Price Payment 8.5(a)(i) JGAAP 1.1 Joint Inventions 9.1(c)(iii) Joint Steering Committee Rollover Stockholder Recitals Intellectual Property 8.13 Intercompany Indebtedness 8.13 Intervening Event 8.13 IRS 8.13 IT Systems 8.13 Knowledge 8.13 Law or Laws 8.13 Lien 3.2(a) Kaken Preamble Kaken Housemarks 9.6(b) Kaken Indemnitees 11.1 Kaken Inventions 9.1(c)(ii) Kaken Product Mark 9.6(a) Kaken Sublicense Agreement 2.1(c) Lilly 1.86 Losses 11.1 Malware 8.13 Marketing Period 8.13 Material Company Intellectual Property 8.13 Annex-3 Defined Terms Section Major Spruce Partner 2.2 Manufacturing Technology Transfer Material Real Property Lease(s) 3.17(b) Merger Recitals Merger Sub Preamble Merger Transactions Recitals No-Shop Period Start Date 5.2(a) NYSE 8.13 OFAC 3.9(d) Order 3.7(b) Owned Intellectual Property 8.13 Owned Real Property 3.17(a) Parent Preamble Parent Benefit Plans 5.9(b) Parent Disclosure Letter Article IV Parent Required Governmental Approvals 4.3(a) Parent Termination Fee 8.13 Paying Agent 2.2(a) Per Share Merger Consideration 2.1(a) Permit 3.9(a) Permitted Encumbrances 8.13 Person 8.13 Proxy Statement 3.4(a) Record Holder of Shares 2.2(b) Redacted Fee Letter 4.5(a) Release 8.13 Relevant Person 3.9(c) Representatives 5.2(a) Required Financial Information 5.15(c)(v) Rollover Agreement 7.2(bRecitals Rollover Shares Recitals Rollover Stockholders Recitals RSU 2.3(c) NDA 1.56 NonAnnex-4 Defined Terms Section Xxxxxxxx-Bankrupt Party 15.13 Party Preamble Payment 8.9(bXxxxx Act 8.13 SEC 8.13 Securities Act 8.13 Share or Shares 2.1(a) Pharmacovigilance Agreement 5.8 Product Materials 4.6 Reconciliation Amount 8.5(a)(iSoftware 8.13 Solvent 8.13 Special Committee Recitals Stock Appreciation Right 2.3(b) Remedial Action 5.9 Right Stockholders’ Meeting 5.4 Stock Plans 3.2(a) Stock Option 2.3(a) Subsidiary 8.13 Superior Proposal 8.13 Surviving Corporation 1.2 Takeover Statute 3.10 Tax or Taxes 8.13 Tax Return 8.13 Termination Date 7.2(a) Termination Fee 8.13 Trademarks 8.13 Trade Secrets 8.13 Transaction Litigation 5.17 Transactions Recitals UK Bribery Act 8.13 WARN 3.13 Annex-5 EXHIBIT A CERTIFICATE OF INCORPORATION OF XXXXXX INTERNATIONAL, INC. THE UNDERSIGNED, being a natural person for the purpose of Reference 5.5 ROFN 6.6 ROFN Exercise Period 6.6 ROFN Exercise Notice 6.6 ROFN Negotiation Period 6.6 ROFN Offer Notice 6.6 Royalty Term 8.4(b) SEC 12.3(c) Spruce Preamble Spruce Indemnitees 11.2 Spruce Inventions 9.1(c)(i) Spruce Partner 2.2 Step-In Rights 9.2(e) Tax Changing Decision 8.9(b) Tax Documents 8.1 Term 13.1 Territory Development Plan 4.2 Territory Expansion Opportunity 6.6 Transfer Price 8.4(a)(i) Working Group 3.5organizing a corporation under the Delaware General Corporation Law (the “DGCL”), hereby certifies that: FIRST: The name of the corporation is Xxxxxx International, Inc. (the “Corporation”).

Defined Terms Section. Alliance Manager 3.1 Auditor 10.4(c) Bankruptcy Event 13.5 Bankrupt Party 15.13 Claims 11.1 Clinical Supply Agreement 7.1 Commercialization Plan 6.2(a) Commercial Supply Agreement 7.2(a) Competing Program 15.5(bCertificate Section 2.5.2 CGCL Recitals Closing Section 1.2 Closing Date Section 1.2 Code Recitals Combination Cash Election Section 2.2.1 Combination Stock Election Section 2.2.1 Community Reinvestment Act Section 3.7(c) Confidentiality Agreement 1.20 DMF 5.1(bSection 6.2 Control Transaction Section 11.2 CVBF Preamble CVBF Affiliated Shareholders Recitals CVBF Articles Section 4.2 CVBF Balance Sheet Section 4.9(c) CVBF Bank Recitals CVBF Benefit Plan Section 7.4(a) CVBF Board Section 4.5(a) CVBF Board Approval Section 4.5(b) CVBF Board Recommendation Section 5.3(b) CVBF Bylaws Section 4.2 CVBF Common Stock Certificates Section 2.4(a) CVBF Confidential Disclosure Schedule Article IV Preamble CVBF Fairness Opinion Section 4.26 CVBF Material Contract Section 4.15 CVBF Options Section 7.1(b) CVBF Permits Section 4.8(a) CVBF Property Section 4.20 CVBF SEC Filings Section 4.9(a) CVBF Shares Section 2.1(a) CVBF Termination Fee Section 11.2(c) Effective Time Section 1.2 Election Section 2.2.1 Election Deadline Section 2.2.2 Election Form Section 2.2.1 Election Form Record Date Section 2.2.1 Exchange Agent Section 2.4(a) Exchange Fund Section 2.5.1 FCBS Preamble Enforcing Party 9.4(cFCBS Affiliated Shareholders Recitals FCBS Affiliates Section 6.6 FCBS Articles Section 3.2 FCBS Balance Sheet Section 3.8(c) Executive Officer 14.1 First Supplemental Development Plan 4.2 GAAP 1.1 Global Development Plan 4.3(dFCBS Bank Recitals FCBS Board Approval Section 3.5(b) Global Strategy 4.3(dFCBS Board Recommendation Section 5.3(b) Global Territory Expansion Opportunity 6.6 GQP Agreement 5.1(bFCBS Bylaws Section 3.2 FCBS Confidential Disclosure Schedule Article III Preamble FCBS Employees Section 7.4(a) ICC 14.2 FCBS Fairness Opinion Section 3.26 - 58 - DEFINED TERMS SECTION FCBS Financial Advisor Section 3.26 FCBS Filings List Section 3.8(a) FCBS Filings Section 3.8(a) FCBS Material Contract Section 3.14 FCBS Option Shares Section 3.3(a) FCBS Options Section 2.5 FCBS Permits Section 3.7 FCBS Property Section 3.20 FCBS Shareholders’ Meeting Section 5.2 FCBS Stock Certificates Section 2.4(b) FCBS Termination Fee Section 11.2(b) Governing Law Section 12.13 Hearing Section 5.2(a) Hearing Notice Section 5.2(a) Holding Company Merger Recitals Indemnified Party 11.3 Liabilities Section 7.5(a) Indemnified Persons Section 7.5(a) Indemnifying Party 11.3 Infringement 9.4(aSection 7.5(a) Infringement Action 9.5 Initial Development Liens Section 3.4 Mailing Date Section 2.2.1 Multiemployer Plan 4.2 Initial Purchase Price Section 3.11(b) Option Payment 8.5(a)(iSection 2.6 Option Payments Section 2.6 Permit Application Section 5.2(a) JGAAP 1.1 Joint Inventions 9.1(c)(iiiProhibited Transaction Section 3.11(b) Joint Steering Committee 3.2(aRegistration Statement on Form S-4 Section 5.2(b) Kaken Preamble Kaken Housemarks 9.6(bRegulatory Authority Section 3.8(d) Kaken Indemnitees Representatives Section 6.2 Stock Election Section 2.2.1 Stock Proration Factor Section 2.2.3(a)(iii) Surviving Bank Section 1.6 Surviving Corporation Section 1.6 Terminating Party Section 11.2(e) Termination Date Section 11.1 Kaken Inventions 9.1(c)(ii) Kaken Product Mark 9.6(a) Kaken Sublicense Agreement 2.1(c) Lilly 1.86 Losses 11.1 Defined Terms Undesignated Shares Section Major Spruce Partner 2.2 Manufacturing Technology Transfer Agreement 7.2(b) NDA 1.56 Non-Bankrupt Party 15.13 Party Preamble Payment 8.9(b) Pharmacovigilance Agreement 5.8 Product Materials 4.6 Reconciliation Amount 8.5(a)(i) Remedial Action 5.9 Right of Reference 5.5 ROFN 6.6 ROFN Exercise Period 6.6 ROFN Exercise Notice 6.6 ROFN Negotiation Period 6.6 ROFN Offer Notice 6.6 Royalty Term 8.4(b) SEC 12.3(c) Spruce Preamble Spruce Indemnitees 11.2 Spruce Inventions 9.1(c)(i) Spruce Partner 2.2 Step-In Rights 9.2(e) Tax Changing Decision 8.9(b) Tax Documents 8.1 Term 13.1 Territory Development Plan 4.2 Territory Expansion Opportunity 6.6 Transfer Price 8.4(a)(i) Working Group 3.52.2.1

Defined Terms Section. Alliance Manager 3.1 Auditor 10.4(cCompany SEC Filings Section 3.8(a) Bankruptcy Event 13.5 Bankrupt Party 15.13 Claims 11.1 Clinical Supply Agreement 7.1 Commercialization Plan 6.2(a) Commercial Supply Agreement 7.2(a) Competing Program 15.5(bCompany Shareholders’ Meeting Section 5.2 Company Termination Fee Section 11.2(b) Confidentiality Agreement 1.20 DMF 5.1(bSection 6.2 Control Transaction Section 11.2 Effective Time Section 1.2 Exchange Agent Section 2.4(a) Effective Date Preamble Enforcing Party 9.4(cGoverning Law Section 12.13 Holding Company Merger Recitals Indemnified Liabilities Section 7.5(a) Executive Officer 14.1 First Supplemental Development Plan 4.2 GAAP 1.1 Global Development Plan 4.3(dIndemnified Persons Section 7.5(a) Global Strategy 4.3(d) Global Territory Expansion Opportunity 6.6 GQP Agreement 5.1(b) ICC 14.2 Indemnified Party 11.3 Indemnifying Party 11.3 Infringement 9.4(aSection 7.5(a) Infringement Action 9.5 Initial Development Liens Section 3.4 Multiemployer Plan Section 3.11(b) Parent Preamble Parent Affiliated Shareholders Recitals Parent Articles Section 4.2 Initial Purchase Price Payment 8.5(a)(iParent Balance Sheet Section 4.9(c) JGAAP 1.1 Joint Inventions 9.1(c)(iiiParent Bank Recitals Parent Benefit Plan Section 7.4(a) Joint Steering Committee 3.2(aParent Board Section 4.5(a) Kaken Parent Board Approval Section 4.5(b) Parent Board Recommendation Section 5.3(b) Parent Bylaws Section 4.2 Parent Confidential Disclosure Schedule Article IV Preamble Kaken Housemarks 9.6(bParent Fairness Opinion Section 4.26 Parent Material Contract Section 4.15 Parent Options Section 7.1(b) Kaken Indemnitees Parent Permits Section 4.8(a) Parent SEC Filings Section 4.9(a) Parent Shareholders’ Meeting Section 5.2 Parent Shares Section 2.1(a) Parent Stock Certificates Section 2.4(a) Prohibited Transaction Section 3.11(b) Representatives Section 6.2 Surviving Bank Section 1.6 Surviving Corporation Section 1.6 Termination Date Section 11.1 Kaken Inventions 9.1(c)(ii) Kaken Product Mark 9.6(a) Kaken Sublicense Agreement 2.1(c) Lilly 1.86 Losses 11.1 Defined Terms Terminating Party Section Major Spruce Partner 2.2 Manufacturing Technology Transfer Agreement 7.2(b) NDA 1.56 Non-Bankrupt Party 15.13 Party Preamble Payment 8.9(b) Pharmacovigilance Agreement 5.8 Product Materials 4.6 Reconciliation Amount 8.5(a)(i) Remedial Action 5.9 Right of Reference 5.5 ROFN 6.6 ROFN Exercise Period 6.6 ROFN Exercise Notice 6.6 ROFN Negotiation Period 6.6 ROFN Offer Notice 6.6 Royalty Term 8.4(b) SEC 12.3(c) Spruce Preamble Spruce Indemnitees 11.2 Spruce Inventions 9.1(c)(i) Spruce Partner 2.2 Step-In Rights 9.2(e) Tax Changing Decision 8.9(b) Tax Documents 8.1 Term 13.1 Territory Development Plan 4.2 Territory Expansion Opportunity 6.6 Transfer Price 8.4(a)(i) Working Group 3.511.2(e)

Defined Terms Section. Alliance Manager 3.1 Auditor 10.4(cAcceptable Confidentiality Agreement Section 4.4(b) Adverse Recommendation Change Section 4.4(d) Agreement Recitals Assumption Documents Section 4.13(a) Assumption Expenses Section 4.13(b) Bankruptcy Event 13.5 Bankrupt Party 15.13 Claims 11.1 Clinical Supply Agreement 7.1 Commercialization Plan 6.2(aand Equity Exception Section 2.2(h) Commercial Supply Agreement 7.2(aBCBCA Recitals CanCo SPV Recitals Capital Expenditure Budget Section 2.14(d) Competing Program 15.5(bCapital Expenditures Section 2.14(d) Chosen Court Section 7.4(b) Confidentiality Agreement 1.20 DMF 5.1(bSection 4.2(b) Continuing REIT Employee Section 4.8(a) D&O Insurance Section 4.7(b) Development Expenditures Section 2.14(d) Development Expenditure Budget Section 2.14(d) Development Projects Section 2.14(d) Exchange Act Section 2.2(c) Existing Indebtedness Section 2.17(a)(vii) Existing Lenders Section 4.13(a) Existing Loan Documents Section 2.17(a)(v) Expense Amount Section 6.3(d) Financing Section 4.14(a) Ground Leased Real Property Section 2.14(b) Ground Leases Section 2.14(b) Guarantor Recitals Guaranty Recitals Indemnified Party Section 4.7(a) Indemnifying Party Section 4.7(a) Interim Period Section 4.1 JV Entity Section 2.1(d) Maximum Amount Section 4.7(b) Notice of Change of Recommendation Section 4.4(e) Operating Budget Section 2.14(d) Operating Expenses Section 2.14(d) Outside Date Section 6.1(b)(ii) Original Effective Date Preamble Enforcing Section 1.7(c) Owned Real Property Section 2.14(a) Participation Agreements Section 2.14(f) Participation Interest Section 2.14(f) Participation Party 9.4(cSection 2.14(f) Executive Officer 14.1 First Supplemental Development Permit Section 2.9(a) Permitted Distribution Section 4.10 Purchaser Recitals Purchaser Plan 4.2 GAAP 1.1 Global Development Plan 4.3(dSection 4.8(a) Global Strategy 4.3(dPurchaser Termination Fee Section 6.3(c) Global Territory Expansion Opportunity 6.6 GQP Agreement 5.1(bREIT Recitals REIT Board Section 2.2(h) ICC 14.2 Indemnified REIT Board Recommendation Section 1.4(c) REIT Disclosure Letter Article II REIT Employee Benefit Plans Section 2.11(a) REIT Intellectual Property Section 2.16(a) REIT Leased Real Property Section 2.14(c) REIT Leases Section 2.14(c) REIT Material Contract Section 2.17(a) REIT Opinion Section 5.2(c) REIT Permit Section 2.9(a) REIT Space Leases Section 2.14(e) REIT Termination Fee Section 6.3 Relevant Taxation Year Section 6.4(a) Rent Rolls Section 2.14(e) Restructuring Transactions Section 4.11(a) Section 6.3 Amount Section 6.4(a) Third Party 11.3 Indemnifying Party 11.3 Infringement 9.4(aSection 2.14(h) Infringement Action 9.5 Initial Development Plan 4.2 Initial Purchase Price Payment 8.5(a)(iTransaction Litigation Section 4.3(b) JGAAP 1.1 Joint Inventions 9.1(c)(iiiTransfer Notice Rights Section 4.15 WARN Section 2.12(d) Joint Steering Committee 3.2(a) Kaken Preamble Kaken Housemarks 9.6(b) Kaken Indemnitees 11.1 Kaken Inventions 9.1(c)(ii) Kaken Product Mark 9.6(a) Kaken Sublicense Agreement 2.1(c) Lilly 1.86 Losses 11.1 Defined Terms Section Major Spruce Partner 2.2 Manufacturing Technology Transfer Agreement 7.2(b) NDA 1.56 Non-Bankrupt Party 15.13 Party Preamble Payment 8.9(b) Pharmacovigilance Agreement 5.8 Product Materials 4.6 Reconciliation Amount 8.5(a)(i) Remedial Action 5.9 Right of Reference 5.5 ROFN 6.6 ROFN Exercise Period 6.6 ROFN Exercise Notice 6.6 ROFN Negotiation Period 6.6 ROFN Offer Notice 6.6 Royalty Term 8.4(b) SEC 12.3(c) Spruce Preamble Spruce Indemnitees 11.2 Spruce Inventions 9.1(c)(i) Spruce Partner 2.2 Step-In Rights 9.2(e) Tax Changing Decision 8.9(b) Tax Documents 8.1 Term 13.1 Territory Development Plan 4.2 Territory Expansion Opportunity 6.6 Transfer Price 8.4(a)(i) Working Group 3.5addition to the other terms defined throughout this Agreement, which are listed above, the following terms shall have the following meanings when used in this Agreement: