Common use of Development and Regulatory Milestones Clause in Contracts

Development and Regulatory Milestones. Licensee shall notify Sanofi of achievement of the development and regulatory milestone events described in the tables below (each a “Development and Regulatory Milestone Event”) within [***]calendar days of achievement thereof with respect to each Licensed Product. On a Licensed Product-by-Licensed Product basis, Licensee shall pay Sanofi the following non-refundable, non-creditable development and regulatory milestone payments described in the tables below for the applicable Licensed Product to achieve the corresponding Development and Regulatory Milestone Event (each a “Development and Regulatory Milestone Payment”) within [***] calendar days after receipt of an invoice therefor from Sanofi, which invoice Sanofi shall provide to Licensee following Sanofi’s receipt of notice from Licensee of the achievement of the applicable Development and Regulatory Milestone Event. Each Development and Regulatory Milestone Payment shall be payable only once for each Licensed Product that achieves such corresponding Development and Regulatory Milestone Event. Development and Regulatory Milestone Event Development and Regulatory Milestone Payment (USD) 1st Indication 2nd Indication

Development and Regulatory Milestones. Licensee shall notify Sanofi of achievement of the development and regulatory milestone events described in the tables below (each a “Development and Regulatory Milestone EventEvents”) within [***]calendar days ] of achievement thereof with respect to each Licensed Productthereof. On a Licensed Product-by-Licensed Product basis, Licensee shall pay Sanofi the following non-refundable, non-creditable development and regulatory milestone payments described in the tables below for the applicable Licensed Product to achieve the corresponding Development and Regulatory Milestone Event Events (each a “Development and Regulatory Milestone PaymentPayments”) within [***] calendar days after receipt of an invoice therefor from Sanofi, which invoice Sanofi shall provide to Licensee following Sanofi’s receipt of notice from Licensee of the achievement of the applicable Development and Regulatory Milestone Event. In the event that Development and Regulatory Milestone Event 2, 3 or 4 below is achieved before Development and Regulatory Milestone Event 1, then then the Development and Regulatory Milestone Payment for 1 shall become due and payable upon the achievement of Development and Regulatory Milestone Event 2, 3 or 4, as the case may be. Each Development and Regulatory Milestone Payment shall be payable only once for each regardless of the number of Licensed Product Products that achieves achieve such corresponding Development and Regulatory Milestone Event. : Development and Regulatory Milestone Event Events Development and Regulatory Milestone Payment (USD) 1st Indication 2nd IndicationPayments 1 [***] [***] 2 [***] [***] 3 [***] [***] 4 [***] [***]

Development and Regulatory Milestones. Licensee shall notify Sanofi of achievement of the development and regulatory milestone events described in the tables below (each a “Development and Regulatory corresponding Milestone Event”) Event within [***]] calendar days of achievement thereof with respect to each Licensed Productthereof. On a Licensed Product-by-Licensed Product basis, Licensee shall pay Sanofi the following non-refundable, non-non- creditable development and regulatory milestone payments described in the tables below for the applicable Licensed Product to achieve the corresponding Development and Regulatory Milestone Event (each a “Development and Regulatory Milestone Payment”) within [***] calendar days after receipt of an invoice therefor from Sanofi, which invoice Sanofi shall will provide to Licensee following Sanofi’s receipt of notice from Licensee of the achievement of the applicable corresponding Milestone Event from Licensee. Milestone Event Milestone Payment 1 [***] [ ***] 2 [***] [ ***] 3 [***] [ ***] 4 [***] [ ***] 5 [***] [ ***] 6 [***] [ ***] 7 [***] [ ***] 8 [***] [ ***] Each of the Development and Regulatory regulatory Milestone EventPayments listed in the table above will be payable by Licensee to Sanofi only once. Each Except with respect to any Sublicense Revenue or Transfer Revenue payments (which may exceed the amounts in the table above), the total Development and regulatory Milestones Payments payable by Licensee to Sanofi hereunder shall be [***]. If Licensee receives a milestone payment from any sublicensee under a Sublicense Agreement for achievement of any milestone event listed above, then [***]. In the event that Development and regulatory Milestone Event 2, 3, 4,or 5 above is achieved before Development and regulatory Milestone Event 1, then the Development and Regulatory Milestone Payment for 1 shall be become due and payable only once for each Licensed Product that achieves such corresponding Development and Regulatory Milestone Event. upon the achievement of Development and Regulatory Milestone Event Development and Regulatory Milestone Payment (USD) 1st Indication 2nd Indication2, 3, 4 or 5, as the case may be.

Development and Regulatory Milestones. Licensee shall notify Sanofi of achievement of the development and regulatory milestone events described in the tables below (each a “Development and Regulatory Milestone EventEvents”) within [***]calendar days ] of achievement thereof with respect to each Licensed Productthereof. On a Licensed Product-by-Licensed Product basis, Licensee shall pay Sanofi the following non-refundable, non-creditable development and regulatory milestone payments described in the tables below for the applicable Licensed Product to achieve the corresponding Development and Regulatory Milestone Event Events (each a “Development and Regulatory Milestone PaymentPayments”) within [***] calendar days after receipt of an invoice therefor from Sanofi, which invoice Sanofi shall provide to Licensee following Sanofi’s receipt of notice from Licensee of the achievement of the applicable Development and Regulatory Milestone Event. In the event that Development and Regulatory Milestone Event 2, 3 or 4 below is achieved before Development and Regulatory Milestone Event 1, then then the Development and Regulatory Milestone Payment for 1 shall become due and payable upon the achievement of Development and Regulatory Milestone Event 2, 3 or 4, as the case may be. Each Development and Regulatory Milestone Payment shall be payable only once for each regardless of the number of Licensed Product Products that achieves achieve such corresponding Development and Regulatory Milestone Event. : Development and Regulatory Milestone Event Events Development and Regulatory Milestone Payment (USD) 1st Indication 2nd IndicationPayments 1 [***] [***] 2 [***] [***] 3 [***] [***] 4 [***] [***] 5 [***] [***] 6 [***] [***]