Common use of FIRST AMENDMENT TO LOAN AND SECURITY AGREEMENT Clause in Contracts

FIRST AMENDMENT TO LOAN AND SECURITY AGREEMENT. This First Amendment to Loan and Security Agreement (the “Amendment”) is made and entered into as of July 13, 2016 by and between PACIFIC WESTERN BANK, a California state chartered bank (“Bank”), and RUBIUS THERAPEUTICS, INC. (“Borrower”).

FIRST AMENDMENT TO LOAN AND SECURITY AGREEMENT. This First Amendment to Loan and Security Agreement (the this “Amendment”) is made and entered into as of July 13March 12, 2016 2021, by and between PACIFIC WESTERN BANK, a California state chartered bank (“Bank”), and RUBIUS THERAPEUTICSXILIO DEVELOPMENT, INC. and XILIO CONCERTO LLC (individually and collectively referred to as “Borrower”).

FIRST AMENDMENT TO LOAN AND SECURITY AGREEMENT. This First Amendment to Loan and Security Agreement (the this “Amendment”) is made and entered into as of July 13August 1, 2016 2019, by and between PACIFIC WESTERN BANK, a California state chartered bank (“Bank”), and RUBIUS THERAPEUTICSAXXXXX PHARMACEUTICALS, INC. (“Borrower”).