Common use of Pricing Information Provided Orally by Underwriters Clause in Contracts

Pricing Information Provided Orally by Underwriters. Public offering price: $2.25 per share Number of Shares: 26,666,667 Option Shares: 2,666,666

Pricing Information Provided Orally by Underwriters. Public The public offering price: price per Share is $2.25 per share Number 18.00. The number of Shares: 26,666,667 Underwritten Shares is 8,500,000. The number of Option Shares: 2,666,666Shares is 1,275,000. Annex B Written Testing-the-Waters Communications None. Annex C Form of Opinion of Counsel for the Company

Pricing Information Provided Orally by Underwriters. Public offering priceprice per Share: $2.25 per share [ ● ] Number of Underwritten Shares: 26,666,667 11,000,000 Number of Option Shares: 2,666,6661,650,000 Annex A Annex B Forms of Opinion of Counsel for the Company and the Selling Stockholders Exhibit A

Pricing Information Provided Orally by Underwriters. Public The public offering price: price per Share is $2.25 per share Number 153.00. The number of Shares: 26,666,667 Underwritten Shares is 8,496,733. The number of Option Shares: 2,666,666Shares is 1,274,509. Exhibit A

Pricing Information Provided Orally by Underwriters. Public offering priceOffering Price per Share: $2.25 per share 6.85 Number of Underwritten Shares: 26,666,667 12,408,760 Number of Option Shares: 2,666,6661,861,314 Annex B Written Testing-the-Waters Communications None. ANNEX C Scholar Rock Holding Corporation Pricing Term Sheet None. Execution Annex D FORM OF LOCK-UP AGREEMENT , 2023

Pricing Information Provided Orally by Underwriters. Public The number of Underwritten Shares is 13,500,000. The number of Option Shares is 2,025,000. The public offering price: $2.25 price per share Number of Shares: 26,666,667 Option Shares: 2,666,666for the Shares is $16.25.