Radiometal binding Sample Clauses
Radiometal binding. 4.1. Tg2576 (n=3) and non-Tg (n=3) mice will be injected i.v. with 64Cu. The animals will be sacrificed at 5 min and the organs will be dissected, weighted and each organ counted. Blood and urine samples will be also collected. The percentage of radioactivity in each organ (%lD/g) will be calculate
4.2. Tg2576 (n=3) and non-Tg (n=3) mice will be injected i.v. with 64Cu-PBT1. The animals will be sacrificed at 5 min and the organs will be dissected, weighted and each organ counted. Blood and urine samples will be also collected. The percentage of radioactivity in each organ (%ID/g) will be calculated.
4.3. Comparison of results Prom. Radiometal binding with and without chelator transporter.
