Common use of Submitting Investigator Clause in Contracts

Submitting Investigator. An investigator who submitted a genomic dataset to an NIH designated data repository (e.g., dbGaP). Study specific DUC addendum phs000360 : eMERGE-I Genome Wide Association Studies of Network Phenotypes Public Posting of Genomic Summary Results - Allowed. NIH Data Access Committee (DAC) : National Human Genome Research Institute Important Contacts : xxxxxxxx@xxxx.xxx.xxx; XXX@xxxx.xxx.xxx In the event of a data management incident, within 24 hours, please contact emails above. Acknowledgement Statement : Sample statements for the acknowledgment of the eMERGE GWAS dataset(s) can be found at the following link: eMERGE dbGaP Acknowledgment Statements (xxxx://xxx.xxxx.xxx.xxx.xxx/projects/gap/cgi-bin/GetPdf.cgi?document_name=eMERGE_Acknowledgement.pdf). Please include all Acknowledgment Statements relevant to the dataset(s) used in your analysis. Name : Health/Medical/Biomedical Consent Group # : 1 Abbreviation : HMB Use of this data is limited to health/medical/biomedical purposes, does not include the study of population origins or ancestry. Data Use Limitation : These data will be used only for health related research, including research to improve methods for health related research. Name : Disease-Specific (Dementia) Consent Group # : 2 Abbreviation : DS-DEM Use of the data must be related to Dementia. Use of the data must be related to health research on dementia or other adult conditions related to the aging process. This includes research to improve methods for conducting research that could be applied to dementia or Data Use Limitation : other adult conditions related to the aging process. For example, studies of conditions like cataract, diabetes, and psoriasis might be appropriate, while conditions like attention deficit hyperactivity disorder (ADHD) and neuroblastoma might not be appropriate. Studies of conditions that are common in both children and the elderly, such as schizophrenia or depression, would not be appropriate if they focused on children or young adults. Studies focused primarily on pediatric populations are not permitted. Name : Health/Medical/Biomedical - Genetic Studies Only-No Insurance Companies Consent Group # : 3 Abbreviation : HM-B-GSO-NIC Data Use Limitation : Use of this data is limited to health/medical/biomedical purposes, does not include the study of population origins or ancestry. Use of the data is limited to genetic studies only. No permitted use: Insurance Companies Name : Health/Medical/Biomedical (GSO) Consent Group # : 4 Abbreviation : HMB-GSO Use of this data is limited to health/medical/biomedical purposes, does not include the study of population origins or ancestry. Data Use Limitation : Use of the data is limited to genetic studies only.

Submitting Investigator. An investigator who submitted a genomic dataset to an NIH designated data repository (e.g., dbGaP). Study specific DUC addendum phs000360 phs000234 : eMERGE-I Genome Wide Association Studies of Network Phenotypes Group Health/UW Aging and Dementia eMERGE Study Public Posting of Genomic Summary Results - Allowed. NIH Data Access Committee (DAC) : National Human Genome Research Institute Important Contacts : xxxxxxxx@xxxx.xxx.xxx; XXX@xxxx.xxx.xxx In the event of a data management incident, within 24 hours, please contact emails above. IC Specific Access Term : none Acknowledgement Statement : Sample statements for the acknowledgment of the eMERGE GWAS dataset(s) can be found at the following link: eMERGE dbGaP Acknowledgment Statements (xxxx://xxx.xxxx.xxx.xxx.xxx/projects/gap/cgi-bin/GetPdf.cgi?document_name=eMERGE_Acknowledgement.pdf). Please include all Acknowledgment Statements relevant to the dataset(s) used in your analysis. Name : Health/Medical/Biomedical Health Research - Marshfield Clinic Consent Group # : 1 Abbreviation : HMB HR_MC Data Use of this data is limited Limitation : May be used for genetic studies to health/medical/biomedical purposeslearn about, does not include the study of population origins prevent, or ancestrytreat health problems. No Permitted Use: Insurance companies Name : Health Research - Vanderbilt U Consent Group # : 2 Abbreviation : HR_VU Data Use Limitation : May be used for genetic studies to learn about, prevent, or treat health problems. Name : Health Research - Group Health Seattle Consent Group # : 3 Abbreviation : HR_GHS research. Data Use Limitation : These data will be used only for health related research, including research to improve methods for health related research. Name : Disease-Specific (Dementia) Dementia or Aging - Group Health Seattle Consent Group # : 2 4 Abbreviation : DS-DEM Use of the data must be related to Dementia. Use of the data must be related AGING_GHS Limited to health research on dementia or other adult conditions related to the aging process. This includes research to improve methods for conducting research that could be applied to dementia or Data Use Limitation : other adult conditions related to the aging process. For example, studies of conditions like cataract, diabetes, and psoriasis might be Data Use Limitation : appropriate, while conditions like attention deficit hyperactivity disorder (ADHD) and neuroblastoma might not be appropriate. Studies of conditions that are common in both children and the elderly, such as schizophrenia or depression, would not be appropriate if they focused on children or young adults. Studies focused primarily on pediatric populations are not permitted. Name : Health/Medical/Biomedical Health Research - Genetic Studies Only-No Insurance Companies Mayo Clinic Consent Group # : 3 5 Abbreviation : HM-B-GSO-NIC HR_MYO Mayo Clinic Data Use Limitation : Use of this data is limited to health/medical/biomedical purposes, does not include the study of population origins or ancestry. Use of the data is limited to may only be used for genetic studies only. No permitted use: Insurance Companies Name : Health/Medical/Biomedical (GSO) Consent Group # : 4 Abbreviation : HMB-GSO Use of this data is limited to health/medical/biomedical purposeslearn about, does not include the study of population origins prevent, or ancestry. Data Use Limitation : Use of the data is limited to genetic studies onlytreat health problems.

Submitting Investigator. An investigator who submitted a genomic dataset to an NIH designated data repository (e.g., dbGaP). Study specific DUC addendum phs000360 Extracorporeal Life Support Survival in a Pediatric Hematopoietic Cellular phs001336 : eMERGETransplant Recipient with Presumed Graft Versus Host Disease-I Genome Wide Association Studies of Network Phenotypes Related Fulminant Myocarditis Public Posting of Genomic Summary Results - Allowed. NIH Data Access Committee (DAC) : National Human Genome Research Institute NICHD-DAC Important Contacts : xxxxxxxx@xxxx.xxx.xxxXX-XXX@xxxx.xxx.xxx; XXX@xxxx.xxx.xxx In the event of a data management incident, within 24 hours, please contact emails above. Before data dissemination, all requestors must provide a local Institutional Review Board (IRB) letter from their respective institutions approving conduct of the proposed research project and to ensure that anonymity and other provisions are adequately guaranteed. The IRB letter must explicitly reference use of the "Extracorporeal Life Support Survival in a Pediatric Hematopoietic Cellular Transplant Recipient with Presumed Graft Versus Host Disease-Related Fulminant Myocarditis" dataset. The requestor of this dataset must also provide a letter of collaboration with Xx. Xxxxxx. Use of these data are limited to health/medical/biomedical purposes. Consequently, studies on population origins or ancestry are not allowed. IC Specific Access Term : Requestor agrees to make results of studies using the data available to the larger scientific community, either through publication or oral presentations. Use of the data includes methods development research (e.g., development of software or algorithms) as it applies to genetic studies. This dataset is limited to genetic studies only. Use of these data to conduct non-genetic research is prohibited. The annual progress report should cite work done that relates specifically to the “Extracorporeal Life Support Survival in a Pediatric Hematopoietic Cellular Transplant Recipient with Presumed Graft Versus Host Disease-Related Fulminant Myocarditis" dataset and not just a generic report for a series of datasets that may also have been requested at the same time. The dataset used for the analyses described in this manuscript were obtained from the database of Genotype and Phenotype (dbGaP) found at xxxx://xxx.xxxx.xxx.xxx.xxx/gap [Accession Number phsxxxxxx]. Samples and associated data for this study ["Extracorporeal Life Support Survival in a Pediatric Hematopoietic Cellular Acknowledgement Statement : Sample statements for Transplant Recipient with Presumed Graft Versus Host Disease-Related Fulminant Myocarditis”] were provided by Xxxxxxx Xxxxxx, M.D., whose project was supported by grants from the acknowledgment Xxxxxx Xxxxxxx Xxxxxxx National Institute of Child Health and Human Development [K12 HD000850], the eMERGE GWAS dataset(s) can be found at the following link: eMERGE dbGaP Acknowledgment Statements (xxxx://xxx.xxxx.xxx.xxx.xxx/projects/gap/cgi-bin/GetPdf.cgi?document_name=eMERGE_Acknowledgement.pdf). Please include all Acknowledgment Statements relevant to the dataset(s) used in your analysisPediatric Blood and Marrow Transplant Foundation, and a National Marrow Donor Program Xxx Xxxxxxxx Xxxxxxxxx Xxxxx. Name : Health/Medical/Biomedical Consent Group # : 1 Abbreviation : HMB Use of this data is limited to health/medical/biomedical purposes(IRB, does not include the study of population origins or ancestry. Data Use Limitation : These data will be used only for health related researchPUB, including research to improve methods for health related research. Name : Disease-Specific (DementiaCOL, MDS, GSO) Consent Group # : 2 Abbreviation : DSHMB-DEM Use of the data must be related to Dementia. Use of the data must be related to health research on dementia or other adult conditions related to the aging process. This includes research to improve methods for conducting research that could be applied to dementia or Data Use Limitation : other adult conditions related to the aging process. For example, studies of conditions like cataract, diabetes, and psoriasis might be appropriate, while conditions like attention deficit hyperactivity disorder (ADHD) and neuroblastoma might not be appropriate. Studies of conditions that are common in both children and the elderly, such as schizophrenia or depression, would not be appropriate if they focused on children or young adults. Studies focused primarily on pediatric populations are not permitted. Name : Health/Medical/Biomedical - Genetic Studies OnlyIRB-No Insurance Companies Consent Group # : 3 Abbreviation : HMPUB-BCOL-GSO-NIC Data Use Limitation : Use of this data is limited to health/medical/biomedical purposes, does not include the study of population origins or ancestry. Use of the data is limited to genetic studies only. No permitted use: Insurance Companies Name : Health/Medical/Biomedical (GSO) Consent Group # : 4 Abbreviation : HMBMDS-GSO Use of this data is limited to health/medical/biomedical purposes, does not include the study of population origins or ancestry. Requestor must provide documentation of local IRB approval. Data Use Limitation : Use Requestor agrees to make results of studies using the data is limited available to genetic studies onlythe larger scientific community. Requestor must provide a letter of collaboration with the primary study investigator(s).

Submitting Investigator. An investigator who submitted a genomic dataset to an NIH designated data repository (e.g., dbGaP). Study specific DUC addendum phs000360 phs000297 : eMERGE-I Genome Wide Association Studies of Network Phenotypes eMERGE Resistant Hypertension Public Posting of Genomic Summary Results - Allowed. NIH Data Access Committee (DAC) : National Human Genome Research Institute Important Contacts : xxxxxxxx@xxxx.xxx.xxx; XXX@xxxx.xxx.xxx In the event of a data management incident, within 24 hours, please contact emails above. Acknowledgement Statement : Sample statements for the acknowledgment of the eMERGE GWAS dataset(s) can be found at the following link: eMERGE dbGaP Acknowledgment Statements (xxxx://xxx.xxxx.xxx.xxx.xxx/projects/gap/cgi-bin/GetPdf.cgi?document_name=eMERGE_Acknowledgement.pdf). Please include all Acknowledgment Statements relevant to the dataset(s) used in your analysis. Name : Health/Medical/Biomedical Health Research - Group Health Seattle Consent Group # : 1 Abbreviation : HMB Use of this data is limited to health/medical/biomedical purposes, does not include the study of population origins or ancestryHR_GHS research. Data Use Limitation : These data will be used only for health related research, including research to improve methods for health related research. Name : Disease-Specific (Dementia) Dementia or Aging - Group Health Seattle Consent Group # : 2 Abbreviation : DS-DEM Use of the data must be related to Dementia. Use of the data must be related AGING_GHS Limited to health research on dementia or other adult conditions related to the aging process. This includes research to improve methods for conducting research that could be applied to dementia or Data Use Limitation : other adult conditions related to the aging process. For example, studies of conditions like cataract, diabetes, and psoriasis might be Data Use Limitation : appropriate, while conditions like attention deficit hyperactivity disorder (ADHD) and neuroblastoma might not be appropriate. Studies of conditions that are common in both children and the elderly, such as schizophrenia or depression, would not be appropriate if they focused on children or young adults. Studies focused primarily on pediatric populations are not permitted. Name : Health/Medical/Biomedical Health Research - Genetic Studies Only-No Insurance Companies Marshfield Clinic Consent Group # : 3 Abbreviation : HM-B-GSO-NIC HR_MC Data Use Limitation : Use of this data is limited to health/medical/biomedical purposes, does not include the study of population origins or ancestry. Use of the data is limited to May be used for genetic studies onlyto learn about, prevent, or treat health problems. No permitted usePermitted Use: Insurance Companies companies Name : Health/Medical/Biomedical (GSO) Health Research - Vanderbilt U Consent Group # : 4 Abbreviation : HMB-GSO HR_VU Data Use of this data is limited Limitation : May be used for genetic studies to health/medical/biomedical purposeslearn about, does not include the study of population origins prevent, or ancestrytreat health problems. Name : Health Research - Mayo Clinic Consent Group # : 5 Abbreviation : HR_MYO Mayo Clinic Data may only be used for genetic studies to learn about, prevent, or treat health problems. Data Use Limitation : Investigators must state in the Data Use of Request their intention to publish or otherwise broadly share any findings from his or her study with the data is limited to scientific community. Name : Health Research - Northwestern U Consent Group # : 6 Abbreviation : HR_NWU May be used for genetic studies only.to learn about, prevent, or treat health problems Data Use Limitation :