Topslam: Topographical Simultaneous Localization and Mapping Sample Clauses

Topslam: Topographical Simultaneous Localization and Mapping. ‌ In this section, we present a new way of extracting pseudo ordering information for high dimensional datasets. This method is part of the contribution for this thesis and is in pre-print Zwiessele and Xxxxxxxx [100]. It has been submitted to the BMC Bioinformatics journal for publication. Extracting pseudo time ordering is a way of ordering samples of a high dimen- sional experiment by supplying pseudo time stamps to each sample according to their intrinsic ordering. In single cell gene experiments, we usually have a rough es- timate of time for each extracted cell, as we can keep track of the days at which the cells where fixed (stopped from their respective differentiation or development). Each cell, however, might have their own intrinsic time at which it divides or de- velops, and thus the rough estimates of extraction time might be misleading. Addi- tionally, in many downstream analyses, such as Gaussian processes, it is preferable to have a more high resolution of time. This lead to the methodology of extracting pseudo time ordering for single cell experiments. Note, that pseudo time ordering can be applied to any high dimensional extraction of information of samples.