1 EXHIBIT 10.12 PARTICIPATION AGREEMENT Dated as of October 2, 1998Participation Agreement • March 31st, 1999 • Applied Analytical Industries Inc • Services-medical laboratories • North Carolina
Contract Type FiledMarch 31st, 1999 Company Industry Jurisdiction
WITNESSETH: -----------Employment Agreement • August 14th, 2003 • Aaipharma Inc • Services-testing laboratories • North Carolina
Contract Type FiledAugust 14th, 2003 Company Industry Jurisdiction
EXHIBIT 10.22 SUBSCRIPTION AGREEMENT THIS SUBSCRIPTION AGREEMENT (this "Agreement") is dated as of October 19, 2001, and is by and between AESGEN, INC., a Delaware corporation ("Aesgen" or the "Company"), aaiPHARMA INCORPORATED, a Delaware corporation...Subscription Agreement • March 11th, 2002 • Aaipharma Inc • Services-testing laboratories • Delaware
Contract Type FiledMarch 11th, 2002 Company Industry Jurisdiction
COMMON STOCKUnderwriting Agreement • November 14th, 1996 • Applied Analytical Industries Inc • Services-medical laboratories • New York
Contract Type FiledNovember 14th, 1996 Company Industry Jurisdiction
Exhibit 2.3 ASSET PURCHASE AGREEMENT by and between NOVARTIS PHARMACEUTICALS CORPORATION, NOVARTIS CORPORATION,Asset Purchase Agreement • January 24th, 2002 • Aaipharma Inc • Services-testing laboratories • New York
Contract Type FiledJanuary 24th, 2002 Company Industry Jurisdiction
AMENDMENT NO. 1 TO ASSET PURCHASE AGREEMENTAsset Purchase Agreement • May 7th, 2004 • Aaipharma Inc • Services-testing laboratories • New York
Contract Type FiledMay 7th, 2004 Company Industry Jurisdiction
RECITALSService Agreement • June 15th, 2004 • Aaipharma Inc • Services-testing laboratories • Georgia
Contract Type FiledJune 15th, 2004 Company Industry Jurisdiction
FIRST AMENDMENT TO CREDIT AGREEMENTCredit Agreement • December 15th, 2003 • Aaipharma Inc • Services-testing laboratories • New York
Contract Type FiledDecember 15th, 2003 Company Industry Jurisdiction
SECURITY AGREEMENT SECURITY AGREEMENT, dated April 23, 2004, made by each of the Grantors referred to below, in favor of Silver Point Finance, LLC, a Delaware limited liability company, in its capacity as collateral agent for the Agents and the...Security Agreement • April 27th, 2004 • Aaipharma Inc • Services-testing laboratories • New York
Contract Type FiledApril 27th, 2004 Company Industry Jurisdiction
PART II AMENDMENTS TO EXISTING LOAN AGREEMENTLoan Agreement • March 11th, 2002 • Aaipharma Inc • Services-testing laboratories
Contract Type FiledMarch 11th, 2002 Company Industry
amongAsset Purchase Agreement • May 7th, 2004 • Aaipharma Inc • Services-testing laboratories • New York
Contract Type FiledMay 7th, 2004 Company Industry Jurisdiction
AAIPHARMA INC.Aaipharma Inc • April 5th, 2002 • Services-testing laboratories • New York
Company FiledApril 5th, 2002 Industry Jurisdiction
RECITALSPledge Agreement • November 15th, 1999 • Applied Analytical Industries Inc • Services-medical laboratories • North Carolina
Contract Type FiledNovember 15th, 1999 Company Industry Jurisdiction
PART II AMENDMENTS TO EXISTING LOAN AGREEMENTLoan Agreement • March 11th, 2002 • Aaipharma Inc • Services-testing laboratories
Contract Type FiledMarch 11th, 2002 Company Industry
EXHIBIT 10.1 [Certain information has been omitted from this document pursuant to a request for confidential treatment submitted to the Securities and Exchange Commission and the omitted information has been separately submitted to the Securities and...Supply Agreement • November 14th, 2003 • Aaipharma Inc • Services-testing laboratories • Delaware
Contract Type FiledNovember 14th, 2003 Company Industry Jurisdiction
FIRST AMENDMENT TO SECURITY AGREEMENTSecurity Agreement • December 15th, 2003 • Aaipharma Inc • Services-testing laboratories • New York
Contract Type FiledDecember 15th, 2003 Company Industry Jurisdiction
ANNEX 1.3 OF THE OPTION AGREEMENT PURCHASE AND ASSIGNMENT AGREEMENTApplied Analytical Industries Inc • January 15th, 1997 • Services-medical laboratories
Company FiledJanuary 15th, 1997 Industry
EXECUTION COPY PLEDGE AND SECURITY AGREEMENT PLEDGE AND SECURITY AGREEMENT, dated as of April 23, 2004, made by aaiPharma Inc., a Delaware corporation (the "Parent"), and each of the other Persons listed on the signature pages hereof or that become a...Pledge and Security Agreement • April 27th, 2004 • Aaipharma Inc • Services-testing laboratories • New York
Contract Type FiledApril 27th, 2004 Company Industry Jurisdiction
BY AND AMONGRegistration Rights Agreement • April 5th, 2002 • Aaipharma Inc • Services-testing laboratories • New York
Contract Type FiledApril 5th, 2002 Company Industry Jurisdiction
EXHIBIT 10.15 SECOND AMENDED AND RESTATED LOAN AGREEMENT Dated as of August 17, 2001Loan Agreement • November 13th, 2001 • Aaipharma Inc • Services-testing laboratories • New York
Contract Type FiledNovember 13th, 2001 Company Industry Jurisdiction
EXECUTION COPY AGREEMENT AND PLAN OF MERGER dated as of August 5, 2003Agreement and Plan of Merger • August 5th, 2003 • Aaipharma Inc • Services-testing laboratories • Delaware
Contract Type FiledAugust 5th, 2003 Company Industry Jurisdiction
EXECUTION COPY FIRST SUPPLEMENTAL INDENTURE FIRST SUPPLEMENTAL INDENTURE (this "Supplemental Indenture"), dated as of April 20, 2004, among aaiPharma Inc., a Delaware corporation (the "Company"), the Guarantor parties hereto and Wachovia Bank,...First Supplemental Indenture • April 27th, 2004 • Aaipharma Inc • Services-testing laboratories • New York
Contract Type FiledApril 27th, 2004 Company Industry Jurisdiction
Exhibit 10.1 FOURTH AMENDMENT TO FINANCING AGREEMENT FOURTH AMENDMENT, dated as of October 22, 2004 (this "Amendment"), to the Financing Agreement, dated as of April 23, 2004 (as amended, restated or otherwise modified from time to time, the...Financing Agreement • October 22nd, 2004 • Aaipharma Inc • Services-testing laboratories • New York
Contract Type FiledOctober 22nd, 2004 Company Industry Jurisdiction
RECITALS:Security Agreement • November 15th, 1999 • Applied Analytical Industries Inc • Services-medical laboratories • North Carolina
Contract Type FiledNovember 15th, 1999 Company Industry Jurisdiction
EXHIBIT 10.10 FIRST AMENDMENT TO LOAN AGREEMENT THIS FIRST AMENDMENT TO LOAN AGREEMENT, dated as of February 13, 1998 (the "First Amendment") is by and between APPLIED ANALYTICAL INDUSTRIES, INC., a corporation organized and existing under the laws of...Loan Agreement • May 15th, 1998 • Applied Analytical Industries Inc • Services-medical laboratories • North Carolina
Contract Type FiledMay 15th, 1998 Company Industry Jurisdiction
EXECUTION COPY AGREEMENT AND PLAN OF MERGER dated as of August 5, 2003Agreement and Plan of Merger • August 6th, 2003 • Aaipharma Inc • Services-testing laboratories • Delaware
Contract Type FiledAugust 6th, 2003 Company Industry Jurisdiction
WITNESSETHAaipharma Inc • March 11th, 2002 • Services-testing laboratories • North Carolina
Company FiledMarch 11th, 2002 Industry Jurisdiction
BETWEENOption Agreement • January 15th, 1997 • Applied Analytical Industries Inc • Services-medical laboratories
Contract Type FiledJanuary 15th, 1997 Company Industry
EXECUTION COPY SECURITY AGREEMENT SECURITY AGREEMENT, dated as of April 23, 2004, made by aaiPharma Inc., a Delaware corporation (the "Parent"), and each of the other Persons listed on the signature pages hereof or that become a party hereto pursuant...Security Agreement • April 27th, 2004 • Aaipharma Inc • Services-testing laboratories • New York
Contract Type FiledApril 27th, 2004 Company Industry Jurisdiction
BETWEENAsset Purchase Agreement • May 12th, 2005 • Aaipharma Inc • Services-testing laboratories • New York
Contract Type FiledMay 12th, 2005 Company Industry Jurisdiction
RECITALSManufacturing Agreement • April 12th, 2002 • Aaipharma Inc • Services-testing laboratories • New York
Contract Type FiledApril 12th, 2002 Company Industry Jurisdiction
ARTICLE II VOTING AGREEMENT AND IRREVOCABLE PROXYStockholder Voting Agreement • August 5th, 2003 • Aaipharma Inc • Services-testing laboratories • Delaware
Contract Type FiledAugust 5th, 2003 Company Industry Jurisdiction
RECITALSAsset Purchase Agreement • June 15th, 2004 • Aaipharma Inc • Services-testing laboratories • Georgia
Contract Type FiledJune 15th, 2004 Company Industry Jurisdiction
BACKGROUND:Manufacturing and Supply Agreement • June 15th, 2004 • Aaipharma Inc • Services-testing laboratories • Virginia
Contract Type FiledJune 15th, 2004 Company Industry Jurisdiction
RECITALSTransfer and Assumption Agreement • June 14th, 2002 • Aaipharma Inc • Services-testing laboratories • New York
Contract Type FiledJune 14th, 2002 Company Industry Jurisdiction