AGREEMENT AND PLAN OF MERGERMerger Agreement • April 30th, 2001 • Vertex Pharmaceuticals Inc / Ma • Pharmaceutical preparations • Delaware
INDENTURE BETWEENIndenture • May 15th, 2000 • Vertex Pharmaceuticals Inc / Ma • Pharmaceutical preparations • New York
EXHIBIT 10.14Lease • March 26th, 2001 • Vertex Pharmaceuticals Inc / Ma • Pharmaceutical preparations
Exhibit 99.5 QUORUM SCIENCES, INC. NONQUALIFIED STOCK OPTION AGREEMENT THIS AGREEMENT dated as of September 1, 1999 (the "Date of Grant") by and between QUORUM SCIENCES, INC., a Delaware corporation, 129-8 West Patrick Street, Frederick, Maryland...Nonqualified Stock Option Agreement • July 23rd, 2001 • Vertex Pharmaceuticals Inc / Ma • Pharmaceutical preparations • Delaware
EXHIBIT 10.29 EMPLOYMENT AGREEMENT AGREEMENT, made and entered into as of the 26th day of October, 2001 by and between Vertex Pharmaceuticals Incorporated, a Massachusetts corporation (together with its successors and assigns, the "Company"), and Ian...Employment Agreement • April 1st, 2002 • Vertex Pharmaceuticals Inc / Ma • Pharmaceutical preparations • Massachusetts
EXHIBIT 1 NOTICE OF EXERCISEStock Option Agreement • July 23rd, 2001 • Vertex Pharmaceuticals Inc / Ma • Pharmaceutical preparations
April 29, 2001Stockholder Agreement • April 30th, 2001 • Vertex Pharmaceuticals Inc / Ma • Pharmaceutical preparations
Exhibit 4.4 SECOND AMENDMENT TO RIGHTS AGREEMENT ------------------------------------ SECOND AMENDMENT TO RIGHTS AGREEMENT (the "Second Amendment") dated as of June 30, 2001, to the Rights Agreement (the "Rights Agreement") dated as of July 1, 1991,...Rights Agreement • August 14th, 2001 • Vertex Pharmaceuticals Inc / Ma • Pharmaceutical preparations • Massachusetts
CREDIT AGREEMENT Dated as of October 13, 2016 amongCredit Agreement • February 23rd, 2017 • Vertex Pharmaceuticals Inc / Ma • Pharmaceutical preparations • New York
This CREDIT AGREEMENT is entered into as of October 13, 2016, among VERTEX PHARMACEUTICALS INCORPORATED, a Massachusetts corporation (the “Borrower”), the Subsidiaries of the Borrower as are or may from time to time become parties to this Agreement as Subsidiary Guarantors (defined herein), the Lenders (defined herein), and BANK OF AMERICA, N.A., as Administrative Agent, Swingline Lender and an L/C Issuer.
SECOND AMENDMENT TO LEASE This SECOND AMENDMENT TO LEASE is made by and between David E. Clem and David M. Roby, Trustees of Fort Washington Realty Trust under Declaration of Trust dated June 19, 1995 and recorded with the Middlesex County (South...Lease • March 26th, 1998 • Vertex Pharmaceuticals Inc / Ma • Pharmaceutical preparations
EXHIBIT 4.1 INDENTURE BETWEENIndenture • November 13th, 2000 • Vertex Pharmaceuticals Inc / Ma • Pharmaceutical preparations • New York
Exhibit 10.32 Form of Change of Control AgreementChange of Control Agreement • March 31st, 2003 • Vertex Pharmaceuticals Inc / Ma • Pharmaceutical preparations • Massachusetts
Exhibit 10.27 EMPLOYMENT AGREEMENT This Employment Agreement (herein referred to as "AGREEMENT") is made and entered into as of this 29th day of April 2001, by and among Aurora Biosciences Corporation (the "COMPANY"), and Harry Stylli ("EXECUTIVE")....Employment Agreement • May 23rd, 2001 • Vertex Pharmaceuticals Inc / Ma • Pharmaceutical preparations • California
EXHIBIT 10.28Credit Agreement • March 3rd, 2000 • Vertex Pharmaceuticals Inc / Ma • Pharmaceutical preparations • Massachusetts
EXHIBIT 2.2 ASSET PURCHASE AGREEMENTAsset Purchase Agreement • March 31st, 2003 • Vertex Pharmaceuticals Inc / Ma • Pharmaceutical preparations • California
EXHIBIT 10.16Lease • March 26th, 2001 • Vertex Pharmaceuticals Inc / Ma • Pharmaceutical preparations • Massachusetts
EXHIBIT 10.2Lease Agreement • November 15th, 1999 • Vertex Pharmaceuticals Inc / Ma • Pharmaceutical preparations
Exhibit 10.9Employment Agreement • March 26th, 2001 • Vertex Pharmaceuticals Inc / Ma • Pharmaceutical preparations • England and Wales
UNDERWRITING AGREEMENT ----------------------Underwriting Agreement • February 25th, 1997 • Vertex Pharmaceuticals Inc / Ma • Pharmaceutical preparations • New York
1 EXHIBIT 4.3 FORM OFRights Agreement • February 25th, 1997 • Vertex Pharmaceuticals Inc / Ma • Pharmaceutical preparations • Massachusetts
VERTEX PHARMACEUTICALS INCORPORATED INDENTURE DEBT SECURITIESIndenture • May 3rd, 2016 • Vertex Pharmaceuticals Inc / Ma • Pharmaceutical preparations • New York
INDENTURE dated as of , 20 , among VERTEX PHARMACEUTICALS INCORPORATED, a Massachusetts corporation (the “Company”), and , as trustee (the “Trustee”).
Exhibit 10.1 Vertex Pharmaceuticals Incorporated has omitted from this Exhibit 10.1 portions of the Agreement for which the Company has requested confidential treatment from the Securities and Exchange Commission. The portions of this Exhibit for...Research Agreement • November 13th, 1998 • Vertex Pharmaceuticals Inc / Ma • Pharmaceutical preparations • Massachusetts
Exhibit 10.26 AURORA BIOSCIENCES CORPORATION 11010 Torreyana Road San Diego, California 92121 Stuart J.M. Collinson, Ph.D. 4810 Tarantella Lane San Diego, CA 92130 Re: Employment Terms Dear Stuart: This letter ("Agreement") sets forth the agreement...Employment Agreement • May 23rd, 2001 • Vertex Pharmaceuticals Inc / Ma • Pharmaceutical preparations • California
EXHIBIT 10.1Research and Development Agreement • November 12th, 1997 • Vertex Pharmaceuticals Inc / Ma • Pharmaceutical preparations • Massachusetts
EXHIBIT 4.2 RESALE REGISTRATRION RIGHTS AGREEMENT amongResale Registration Rights Agreement • November 13th, 2000 • Vertex Pharmaceuticals Inc / Ma • Pharmaceutical preparations • New York
INDENTURE BETWEEN VERTEX PHARMACEUTICALS INCORPORATED, AS ISSUER AND U.S. BANK NATIONAL ASSOCIATION, AS TRUSTEE 4.75% CONVERTIBLE SENIOR SUBORDINATED NOTES DUE 2013 DATED AS OF FEBRUARY 19, 2008Indenture • February 25th, 2008 • Vertex Pharmaceuticals Inc / Ma • Pharmaceutical preparations • New York
INDENTURE, dated as of February 19, 2008, between VERTEX PHARMACEUTICALS INCORPORATED, a corporation duly organized and existing under the laws of the Commonwealth of Massachusetts, having its principal office at 130 Waverly Street, Cambridge, Massachusetts 02139 (the “Company”), and U.S. BANK NATIONAL ASSOCIATION, as trustee (the “Trustee”), having its principal corporate trust office at One Federal Street, Boston, Massachusetts 02110.
VERTEX PHARMACEUTICALS INCORPORATED (a Massachusetts corporation) 9,100,000 Shares of Common Stock PURCHASE AGREEMENTPurchase Agreement • September 15th, 2006 • Vertex Pharmaceuticals Inc / Ma • Pharmaceutical preparations • New York
INDENTURE BETWEEN VERTEX PHARMACEUTICALS INCORPORATED, AS ISSUER AND US BANK NATIONAL ASSOCIATION, AS TRUSTEE 5¾% CONVERTIBLE SENIOR SUBORDINATED NOTES DUE 2011 DATED AS OF SEPTEMBER 17, 2004Indenture • September 17th, 2004 • Vertex Pharmaceuticals Inc / Ma • Pharmaceutical preparations • New York
INDENTURE, dated as of September 17, 2004, between VERTEX PHARMACEUTICALS INCORPORATED, a corporation duly organized and existing under the laws of the Commonwealth of Massachusetts, having its principal office at 130 Waverly Street, Cambridge, Massachusetts 02139 (the “Company”), and US BANK NATIONAL ASSOCIATION, as trustee (the “Trustee”), having its principal corporate trust office at One Federal Street, Boston, Massachusetts 02110.
CREDIT AGREEMENT Dated as of January 7, 2011 among VERTEX PHARMACEUTICALS INCORPORATED, as the Borrower, BANK OF AMERICA, N.A., as Administrative Agent, and The Other Lenders Party HeretoCredit Agreement • May 6th, 2011 • Vertex Pharmaceuticals Inc / Ma • Pharmaceutical preparations • Massachusetts
This CREDIT AGREEMENT (“Agreement”) is entered into as of January 7, 2011, among VERTEX PHARMACEUTICALS INCORPORATED, a Massachusetts corporation (the “Borrower”), each lender from time to time party hereto (collectively, the “Lenders” and individually, a “Lender”), and BANK OF AMERICA, N.A., as Administrative Agent.
EMPLOYMENT AGREEMENTEmployment Agreement • May 1st, 2019 • Vertex Pharmaceuticals Inc / Ma • Pharmaceutical preparations • Massachusetts
This Employment Agreement (this “Agreement”) is made and entered into as of this 28th day of March, 2019, by and between Vertex Pharmaceuticals Incorporated, a Massachusetts corporation (together with its successors and assigns, the “Company”), and Charles F. Wagner, Jr. (the “Executive”).
Dated 10 June 2009 Lease between MEPC Milton Park No. 1 Limited and MEPC Milton Park No. 2 Limited and Vertex Pharmaceuticals (Europe) Limited and Vertex Pharmaceuticals Incorporated relating to Building 86 and 87 Milton ParkLease • August 10th, 2009 • Vertex Pharmaceuticals Inc / Ma • Pharmaceutical preparations • England
LR3. Parties to this lease : Landlord MEPC MILTON PARK NO. 1 LIMITED (Company number 5491670) and MEPC MILTON PARK NO. 2 LIMITED (Company number 5491806), on behalf of MEPC Milton Park Limited Partnership, both of whose registered offices are at 4th Floor Lloyds Chambers 1 Portsoken Street London E1 8LW Tenant VERTEX PHARMACEUTICALS (EUROPE) LIMITED (Company number 2907620) whose registered office is at 88 Milton Park Abingdon Oxfordshire OX14 4RY Other parties VERTEX PHARMACEUTICALS INCORPORATED (A company registered in Massachusetts) of 130 Waverly Street Cambridge Massachusetts MA02139-4242 whose address for service is care of Vertex Pharmaceuticals (Europe) Limited 88 Milton Park Abingdon Oxfordshire OX14 4RY - Guarantor)
EXHIBIT 10.1 VERTEX PHARMACEUTICALS INCORPORATED HAS OMITTED FROM THIS EXHIBIT 10.1 PORTIONS OF THE AGREEMENT FOR WHICH THE COMPANY HAS REQUESTED CONFIDENTIAL TREATMENT FROM THE SECURITIES AND EXCHANGE COMMISSION. THE PORTIONS OF THIS EXHIBIT FOR...License, Development and Commercialization Agreement • November 15th, 1999 • Vertex Pharmaceuticals Inc / Ma • Pharmaceutical preparations • Delaware
EMPLOYMENT AGREEMENTEmployment Agreement • May 12th, 2008 • Vertex Pharmaceuticals Inc / Ma • Pharmaceutical preparations • Massachusetts
AGREEMENT, made and entered into as of February 11, 2008 by and between Vertex Pharmaceuticals Incorporated, a Massachusetts corporation (together with its successors and assigns, the "Company"), and John Alam (the "Executive").
May 18, 2012Change of Control Agreement • February 13th, 2020 • Vertex Pharmaceuticals Inc / Ma • Pharmaceutical preparations • Massachusetts
VERTEX PHARMACEUTICALS INCORPORATED AMENDED AND RESTATED 2006 STOCK AND OPTION PLAN Form of Restricted Stock Unit AwardRestricted Stock Unit Award Agreement • February 13th, 2015 • Vertex Pharmaceuticals Inc / Ma • Pharmaceutical preparations
This Agreement sets forth the terms and conditions of a Restricted Stock Unit Award granted pursuant to the provisions of the Amended and Restated 2006 Stock and Option Plan (as it may be amended or restated, the “Plan”) of Vertex Pharmaceuticals Incorporated (the “Company”) to the Participant whose name appears below, of a contingent entitlement of the Participant to receive the number of Shares of Common Stock of the Company set forth below, pursuant to the provisions of the Plan and on the following express terms and conditions. Capitalized terms not otherwise defined herein shall have the same meanings as set forth in the Plan, and any Restricted Stock Units evidenced hereby are granted subject to the terms of the Plan.
