CASI Pharmaceuticals, Inc (DE) Sample Contracts

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AGREEMENT
Agreement • March 31st, 1999 • Entremed Inc • Services-medical laboratories • Delaware
1 EXHIBIT 10.25
License Agreement • April 10th, 1997 • Entremed Inc • Services-medical laboratories • Massachusetts
1,450,000 Shares ENTREMED, INC. Common Stock UNDERWRITING AGREEMENT
Entremed Inc • February 27th, 2001 • Biological products, (no disgnostic substances) • New York
CASI Pharmaceuticals, Inc. 15,853,658 Shares of Common Stock (par value $0.01 per share) Underwriting Agreement
Underwriting Agreement • March 26th, 2021 • CASI Pharmaceuticals, Inc. • Biological products, (no disgnostic substances) • New York

CASI Pharmaceuticals, Inc., a Delaware corporation (the “Company”), proposes to issue and sell to the several underwriters named in Schedule A (the “Underwriters”) an aggregate of up to 18,231,706 shares of its common stock, par value $0.01 per share (the “Shares”). The 15,853,658 Shares to be sold by the Company are called the “Firm Shares.” In addition, the Company has granted to the Underwriters an option to purchase up to an additional 2,378,048 Shares, which are collectively called the “Option Shares.” The Firm Shares and, if and to the extent such option is exercised, the Option Shares, are collectively called the “Offered Shares.” Oppenheimer & Co. Inc. (“OpCo”) has agreed to act as representative of the several Underwriters (in such capacity, the “Representative”) in connection with the offering and sale of the Offered Shares. To the extent there are no additional underwriters listed on Schedule A, the term “Representative” as used herein shall mean OpCo, as Underwriter, and th

EXECUTION VERSION PURCHASE AGREEMENT
Purchase Agreement • August 14th, 2001 • Entremed Inc • Biological products, (no disgnostic substances) • New York
WITNESSETH
License Agreement • April 10th, 1997 • Entremed Inc • Services-medical laboratories • Massachusetts
ENTREMED, INC. SERIES 2 STOCK PURCHASE WARRANT
Entremed Inc • August 10th, 1999 • Services-medical laboratories • New York
RESEARCH AGREEMENT
Research Agreement • March 30th, 2000 • Entremed Inc • Services-medical laboratories • Massachusetts
OPEN MARKET SALE AGREEMENTSM
Open Market Sale • July 19th, 2019 • CASI Pharmaceuticals, Inc. • Biological products, (no disgnostic substances) • New York

CASI Pharmaceuticals, Inc., a Delaware corporation (the “Company”), proposes, subject to the terms and conditions stated herein, to issue and sell from time to time through Jefferies LLC, as sales agent and/or principal (the “Agent”), shares of the Company’s common stock, par value $.01 per share (the “Common Shares”), on the terms set forth in this agreement (this “Agreement”).

FORM OF SECURITIES PURCHASE AGREEMENT
Form of Securities Purchase Agreement • October 19th, 2017 • CASI Pharmaceuticals, Inc. • Biological products, (no disgnostic substances) • New York

This Securities Purchase Agreement (this “Agreement”) is dated as of October 13, 2017, between CASI Pharmaceuticals, Inc., a Delaware corporation (the “Company”), and each purchaser identified on the signature pages hereto (each, including its successors and assigns, a “Purchaser” and collectively the “Purchasers”).

BACKGROUND
Transition Agreement • April 25th, 2003 • Entremed Inc • Biological products, (no disgnostic substances) • Maryland
20,000,000 Shares CASI Pharmaceuticals, Inc. Common Stock UNDERWRITING AGREEMENT
Underwriting Agreement • July 24th, 2020 • CASI Pharmaceuticals, Inc. • Biological products, (no disgnostic substances) • New York

CASI Pharmaceuticals, Inc., a Delaware corporation (the “Company”), proposes, subject to the terms and conditions contained herein, to sell to you and the other underwriters named on Schedule I to this Agreement (the “Underwriters”), for whom you are acting as Representative (the “Representative”), an aggregate of 20,000,000 shares (the “Firm Shares”) of the Company’s common stock, $0.01 par value per share (the “Common Stock”). The respective amounts of the Firm Shares to be purchased by each of the several Underwriters are set forth opposite their names on Schedule I hereto. In addition, the Company proposes to grant to the Underwriters an option to purchase up to an additional 3,000,000 shares (the “Company Option Shares”) of Common Stock from the Company for the purpose of covering over-allotments in connection with the sale of the Firm Shares. The Firm Shares and the Company Option Shares are collectively called the “Shares.”

FORM OF COMMON STOCK PURCHASE WARRANT entremed, inc.
Entremed Inc • March 6th, 2013 • Biological products, (no disgnostic substances)

THIS COMMON STOCK PURCHASE WARRANT (the “Warrant”) certifies that, for value received, _____________ (the “Holder”) is entitled, upon the terms and subject to the limitations on exercise and the conditions hereinafter set forth, at any time on or after September ___, 2013 (the “Initial Exercise Date”) and on or prior to the close of business on the third anniversary of the Initial Exercise Date (the “Termination Date”) but not thereafter, to subscribe for and purchase from EntreMed, Inc., a Delaware corporation (the “Company”), up to _____ shares (subject to adjustments as provided below) (the “Warrant Shares”) of Common Stock.

CASI PHARMACEUTICALS, inc. cOMMON STOCK SALES AGREEMENT
Sales Agreement • October 29th, 2021 • CASI Pharmaceuticals, Inc. • Biological products, (no disgnostic substances) • New York
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STRICTLY CONFIDENTIAL CASI Pharmaceuticals, Inc.
Letter Agreement • October 19th, 2017 • CASI Pharmaceuticals, Inc. • Biological products, (no disgnostic substances) • New York
STANDBY EQUITY DISTRIBUTION AGREEMENT
Equity Distribution Agreement • June 28th, 2011 • Entremed Inc • Biological products, (no disgnostic substances) • New York

THIS AGREEMENT dated as of June 28, 2011 (this “Agreement”) between YA GLOBAL MASTER SPV LTD., a Cayman Islands exempt limited partnership (the “Investor”), and ENTREMED, INC. a corporation organized and existing under the laws of the State of Delaware (the “Company”).

WHARTON CAPITAL MARKETS LLC
Entremed Inc • April 16th, 2010 • Biological products, (no disgnostic substances) • New York
INVESTMENT AGREEMENT
Investment Agreement • September 19th, 2014 • CASI Pharmaceuticals, Inc. • Biological products, (no disgnostic substances) • Delaware

This INVESTMENT AGREEMENT (this “Investment Agreement”) is made as of September 17, 2014 by and between CASI Pharmaceuticals, Inc., a Delaware corporation (the “Company”), and Spectrum Pharmaceuticals, Inc., a Delaware corporation (the “Investor”).

employment agreement
Employment Agreement • October 24th, 2018 • CASI Pharmaceuticals, Inc. • Biological products, (no disgnostic substances) • Maryland

This EMPLOYMENT AGREEMENT (“Agreement”) is made effective as of September 28, 2018, by and between CASI PHARMACEUTICALS, INC., a Delaware corporation having its principal office at 9620 Medical Center Drive, Suite 300, Rockville, MD 20850 (the “Company”) and GEORGE CHI (the “Executive”).

EMPLOYMENT AGREEMENT
Employment Agreement • March 13th, 2009 • Entremed Inc • Biological products, (no disgnostic substances) • Maryland

This EMPLOYMENT AGREEMENT (“Agreement”), effective as of January 1, 2009, is by and between EntreMed, Inc., a Delaware corporation having its principal office at 9640 Medical Center Drive, Rockville, MD 20850 (the “Company”) and Mark R. Bray (the “Executive”).

EMPLOYMENT AGREEMENT
Employment Agreement • June 6th, 2006 • Entremed Inc • Biological products, (no disgnostic substances) • Maryland

This EMPLOYMENT AGREEMENT (“Agreement”) is made effective as of the date of signature by and between ENTREMED, INC., a Delaware corporation having its principal office at 9640 Medical Center Drive, Rockville, MD 20850 (the “Company”) and Cynthia Wong (the “Executive”).

10,727,500 Shares ENTREMED, INC. Common Stock PLACEMENT AGENCY AGREEMENT
Placement Agency Agreement • December 13th, 2006 • Entremed Inc • Biological products, (no disgnostic substances) • New York

EntreMed, Inc., a Delaware corporation (the “Company”), proposes, subject to the terms and conditions stated herein, to issue and sell up to an aggregate of 10,727,500 shares (the “Shares”) of the Company’s common stock, $0.01 par value per share (the “Common Stock”) to certain investors (each an “Investor” and, collectively, the “Investors”). The Company desires to engage ThinkEquity Partners LLC (“ThinkEquity”) as lead placement agent, and Rodman & Renshaw, LLC (“Rodman” and together with ThinkEquity, the “Placement Agents”) as co-placement agent, as set forth herein in connection with such issuance and sale. ThinkEquity is acting as representative of the Placement Agents (the “Representative”). The Shares are more fully described in the Registration Statement (as hereinafter defined).

SECURITIES PURCHASE AGREEMENT
Securities Purchase Agreement • March 23rd, 2018 • CASI Pharmaceuticals, Inc. • Biological products, (no disgnostic substances) • New York

This Securities Purchase Agreement (this “Agreement”) is dated as of _______, 2018, between CASI Pharmaceuticals, Inc., a Delaware corporation (the “Company”), and each purchaser identified on the signature pages hereto (each, including its successors and assigns, a “Purchaser” and collectively the “Purchasers”).

SECURITIES PURCHASE AGREEMENT
Securities Purchase Agreement • November 13th, 2015 • CASI Pharmaceuticals, Inc. • Biological products, (no disgnostic substances) • New York

This Securities Purchase Agreement (this “Agreement”) is made as of September 20, 2015, between CASI Pharmaceuticals, Inc., a Delaware corporation (the “Company”), [________________], a company formed under the laws of [_________] (“[______]”) and any Person that delivers any portion of the Subscription Amount pursuant to Section 2.02(b) of this Agreement (such Persons, together with [______], jointly and severally, and including their successors and assigns, the “Purchaser”).

Contract
Exclusive Distribution Agreement • April 26th, 2023 • CASI Pharmaceuticals, Inc (DE) • Biological products, (no disgnostic substances)

Certain confidential information contained in this document, marked by brackets and *** asterisk, has been omitted pursuant to Item 601(b)(10)(iv) of Regulation S-K, because it (i) is not material and (ii) would be competitively harmful if publicly disclosed.

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