Exhibit 10.23
PATENT PURCHASE AGREEMENT
THIS PATENT PURCHASE AGREEMENT is made and entered into on this the 4th day
of November, 2005, by and among BioMimetic Therapeutics, Inc. ("BMTI" or
"Buyer") and Institute of Molecular Biology, Inc. ("IMB" or "Seller").
RECITALS
Seller desires to sell to Buyer, and Buyer desires to purchase from Seller
all right, title and interests in and to certain Patent Rights (as defined
below), in exchange for certain consideration as set forth herein, and upon the
other terms and conditions set forth in this Agreement.
NOW, THEREFORE, in consideration of the mutual agreements and covenants
contained herein, the parties hereto agree as follows:
1. PURCHASE AND SALE OF ASSETS.
1.1. ASSETS SOLD. Subject to and in accordance with the terms and
conditions hereof, Buyer hereby purchases from Seller, and Seller will sell,
assign, transfer and convey to Buyer all of its right, title and interest in and
to the following (collectively the "Assets"): all patents and patent
applications (including all continuations, divisionals, continuations-in-part,
reissues and the rights to apply for patents anywhere in the world and any
rights to xxx for past infringements thereof) described on Schedule 1.1 attached
hereto (collectively, the "Patent Rights").
1.2. LIABILITIES RETAINED BY SELLER. Buyer shall not assume, or in any way
be liable or responsible for, any liabilities, obligations or indebtedness of
Seller, whether due or to become due, absolute or contingent, known or unknown
(the "Retained Obligations") other than the obligations of Seller to Xxxxxxxx &
Worcester LLP, Seller's special counsel in an amount not to exceed ** and
obligations, if any, arising after Closing under any contracts related to the
Patent Rights that are specifically assumed by Buyer in writing at the Closing.
2. PURCHASE PRICE.
2.1. PAYMENT OF PURCHASE PRICE. The consideration to be paid by Buyer to
Seller, in consideration of the sale and transfer of the Assets, shall be **.
3. DELIVERIES.
3.1. DELIVERIES OF SELLER. Seller is hereby delivering to Buyer duly
executed assignments of all patents and patent applications contained in the
Patent Rights, in the form of Exhibit 3.1.
** REPRESENTS MATERIAL WHICH HAS BEEN REDACTED AND SEPARATELY FILED WITH THE
SECURITIES AND EXCHANGE COMMISSION PURSUANT TO A REQUEST FOR CONFIDENTIAL
TREATMENT PURSUANT TO RULE 406 UNDER THE SECURITIES ACT OF 1933, AS
AMENDED.
4. REPRESENTATIONS AND WARRANTIES OF SELLER.
Seller hereby represents and warrants to Buyer as follows:
4.1. CORPORATE ORGANIZATION. Seller is a corporation duly organized,
validly existing and in good standing under the laws of the State of Delaware
and has full corporate power and authority to carry on the business of Seller as
it is now being conducted. Attached as Exhibit 4.1 is a certificate of good
standing from the State of Delaware.
4.2. AUTHORIZATION. Seller has full corporate power and authority to enter
into this Agreement and to carry out the transactions contemplated hereby. The
Board of Directors and stockholders of Seller have taken all action required by
law to be taken to authorize the execution and delivery by Seller of this
Agreement, and no other corporate proceedings on the part of Seller are required
to authorize such execution and delivery of this Agreement and the consummation
of the transactions contemplated hereby. Attached as Exhibit 4.2 are copies of
the stockholder and board of directors minutes authorizing the sale to Buyer.
This Agreement has been duly executed and delivered by Seller and is a valid and
binding obligation of Seller enforceable in accordance with its terms.
4.3. NO VIOLATION. Neither the execution and delivery of this Agreement nor
the consummation of the transactions contemplated hereby will violate any
provision of the Certificate of Incorporation or Bylaws of Seller or violate, or
be in conflict with, or constitute a default (or an event which, with notice or
lapse of time or both, would constitute a default) under any debt or obligation
of Seller or violate any statute or law or any judgment, decree, order,
regulation or rule of any court or governmental authority.
4.4. TITLE TO ASSETS; ENCUMBRANCES. Seller has good, valid and marketable
title to the Assets, free and clear of all material liens, claims, charges,
security interests or other encumbrances of any nature, other than liens for
taxes not yet due and payable. Seller has not granted any license or other right
in or to the Patent Rights. There are no contracts or agreements of any nature
related to or affecting the Patent Rights.
4.5. LITIGATION. There is no action, suit, inquiry, proceeding or
investigation by or before any court or governmental or other regulatory or
administrative agency known to Seller which questions or challenges the validity
of this Agreement or any action taken or to be taken by Seller pursuant to this
Agreement or which questions or challenges the validity of any of the Patent
Rights; nor to Seller's knowledge is there any valid basis therefore.
4.6. CONSENTS. No consent of any person is necessary to the consummation of
the transactions contemplated hereby.
4.7. GOOD TITLE CONVEYED. Seller has or will at the Closing have the power
and the right to sell, assign, transfer and deliver to Buyer, and upon
consummation of the transactions contemplated by this Agreement, Buyer will
acquire good, valid and marketable title to the Assets, free and clear of all
mortgages, pledges, liens, security interests or other such encumbrances,
interests or charges of any kind.
2
4.8. NO BUYER WAIVER. The representations and warranties of Seller shall
not be deemed waived or otherwise affected by any investigation by Buyer.
5. FURTHER ASSURANCES.
5.1. FURTHER ASSURANCES. Upon the request of either Buyer or Seller, the
other party will execute and deliver to the requesting party, or such party's
nominee, all such instruments and documents of further assurance or otherwise,
and will do any and all such acts and things as may reasonably be required to
carry out the obligations of such party hereunder, to vest in Buyer good and
marketable title to the Assets to be transferred hereunder and to more
effectively consummate the transactions contemplated hereby. Seller will
cooperate with Buyer from time-to-time at Buyer's request and expense and
provide all information in its possession in order to enable Buyer to enforce
the Patent Rights and to defend any claims challenging or involving the Patent
Rights.
6. MISCELLANEOUS.
6.1. NOTICES. All notices, approvals or other communications provided for
herein to be sent or given to Buyer shall be deemed validly and properly given
or made if in writing and delivered by hand or by certified or registered mail,
return receipt requested, addressed to:
If to Buyer:
BioMimetic Therapeutics, Inc.
000-X Xxxxxx Xxxx Xxxx
Xxxxxxxx, XX 00000
ATTN: General Counsel
with a copy to:
Xxxx Xxxxxxxxx
Xxxxxxx Xxxxxx Xxxx Xxxxxxx & Manner, P.C.
000 Xxxxxxxxx Xxxxxx, #0000
Xxxxxxxxx, XX 00000-0000
if to Seller:
Institute of Molecular Biology, Inc.
X.X. Xxx 0000
Xxxxxxxxxx, XX 00000
Attn: Xxxx Xxxxxx
with a copy to:
Xxxxxxxx & Worcester LLP
Xxx Xxxx Xxxxxx Xxxxxx
Xxxxxx, XX 00000
Attn: Xxxxxxxxx X. Xxxxxxxxxx, Xx., Esq.
3
Either of the parties hereto may give notice to the other at any time by the
methods specified above of a change in the address at which, or the persons to
whom, notices addressed to it are to be delivered in the future, and such notice
shall be deemed to amend this Section until superseded by a later notice of the
same type. Any notice given by mail as aforesaid shall be conclusively deemed to
have been received by a party hereto and be effective on the second business day
after the day on which mailed to the address set forth above.
6.2. HEADINGS. The headings of the Sections and Articles of this Agreement
are inserted for convenience only and shall not constitute a part hereof or
affect in any way the meaning or interpretation of this Agreement.
6.3. ASSIGNMENT. This Agreement shall be binding upon and shall inure to
the benefit of the parties hereto and their respective successors and assigns,
provided, however, that none of such parties shall assign this Agreement or its
rights hereunder without the written consent of the other.
6.4. COUNTERPARTS. This Agreement may be executed in two or more
counterparts, each of which shall be deemed an original, but all of which
together shall constitute one and the same instrument.
6.5. GOVERNING LAW. This Agreement shall be governed by and construed in
accordance with the laws of the State of Delaware.
6.6. AMENDMENT AND MODIFICATION. Any amendment, modification or supplement
to this Agreement shall be in writing signed by the party or parties to be
charged.
6.7. ENTIRE AGREEMENT. This Agreement, the Exhibits hereto and the other
documents delivered pursuant hereto constitute the entire agreement of the
parties in respect of the subject matter hereof and supersede all prior
agreements, communications, representations or warranties, whether oral or
written, among the parties in respect to such subject matter.
4
IN WITNESS WHEREOF, the parties hereto have caused this Agreement to be
duly executed as of the day and year first written above.
BIOMIMETIC THERAPEUTICS, INC.
By: /s/ Xxxxxx Xxxxx
---------------------------------
Title: President
INSTITUTE FOR MOLECULAR BIOLOGY, INC.
By: /s/ Xxxx X. Xxxxxx
---------------------------------
Title: President
5
Exhibit A
C & E REF. NO. COUNTRY TYPE STATUS APPLICATION NO. FILED PATENT NO. ISSUED PATENT EXP. DATE
-------------- ------------- ---- --------- --------------- ------------ ---------- ----------- ----------------
WOUND HEALING AND BONE REGENERATION
02854-007AT 1 Austria EPC Granted 87907900.2 13-Nov-1987 0289584 05-May-1993 13-Nov-07
02854-007AU1 Australia PCT Granted 83289/87 13-Nov-1987 600069 02-Aug-1990 00-Xxx-00
00000-000XX0 Xxxxxxx EPC Granted 87907900.2 13-Nov-1987 0289584 05-May-1993 13-Nov-03
02854-007CA1 Canada PCT Granted 551,909 16-Nov-1987 1,322,714 05-Oct-1993 5-Jan-10
00000-000XX0 Xxxxxxxxxxx EPC Granted 87907900.2 13-Nov-1987 0289584 05-May-1993 00-Xxx-00
00000-000XX0 Xxxxx PCT Granted 87101250.2 14-Nov-1987 87101250.2 30-Oct-1994 00-Xxx-00
00000-000XX0 Xxxxxxx EPC Granted 87907900.2 13-Nov-1987 0289584 05-May-1993 00-Xxx-00
00000-000XX0 Xxxxxxx PCT Allowed 3932/88 13-Nov-1987
02854-007EP1 Europe PCT Granted 87907900.2 13-Nov-1987 0289584 05-May-1993 00-Xxx-00
00000-000XX0 Xxxxxx EPC Granted 87907900.2 13-Nov-1987 0289584 05-May-1993 00-Xxx-00
00000-000XX0 Xxxxxx EPC Granted 89906917.3 22-May-1989 0419534 03-Aug-1994 00-Xxx-00
00000-000XX0 Xxxxx Xxxxxxx EPC Granted 87907900.2 13-Nov-1987 0289584 05-May-1993 00-Xxx-00
00000-000XX0 Xxxxxxx PCT Granted 3075/87 13-Nov-1987 60517 20-Jul-1994 13-Nov-03
00000-000XX0 Xxxxx EPC Granted 87907900.2 13-Nov-1987 0289584 05-May-1993 00-Xxx-00
00000-000XX0 Xxxxx PCT Granted 500179/87 13-Nov-1987 1868245 26-Aug-1994 00-Xxx-00
00000-000XX0 Xxxxx PCT Granted 88-700829 13-Nov-1987 106280 17-Oct-1996 1-May-11
00000-000XX0 Xxxxxxxxxx EPC Granted 87907900.2 13-Nov-1987 0289584 05-May-1993 00-Xxx-00
00000-000XX0 Xxxxxxxxxxx EPC Granted 87907900.2 13-Nov-1987 0289584 05-May-1993 00-Xxx-00
00000-000XX0 Xxx Xxxxxxx PCT Granted 222551 16-Nov-1987 222551 00-Xxx-00
00000-000XX0 Xxxxxx EPC Granted 87907900.2 13-Nov-1987 0289584 05-May-1993 00-Xxx-00
00000-000XX0 Xxxxxx PCT Granted 76107672 15-Dec-1987 NI-51493 30-Jan-1992 00-Xxx-00
00000-000XX0 Xxxxx Xxxxxx PCT Granted 87/8566 16-Nov-1987 87/8566 26-Jul-1989 16-Nov-07
WOUND HEALING
02854-010AT1 Austria EPC Granted 89901681.0 20-Dec-1988 0394349 27-Oct-1993 20-Dec-08
02854-010AU1 Australia PCT Granted 37472/89 20-Dec-1988 613776 03-Dec-1991 00-Xxx-00
00000-000XX0 Xxxxxxx XXX Granted 89901681.0 20-Dec-1988 0394349 27-Oct-1993 20-Dec-08
02854-010CA1 Canada PCT Granted 586,562 21-Dec-1988 1,322,164 14-Sep-1993 17-Sep-10
00000-000XX0 Xxxxxxxxxxx EPC Granted 89901681.0 20-Dec-1988 0394349 27-Oct-1993 20-Dec-08
00000-000XX0 Xxxxx PCT Granted 88109273.8 21-Dec-1988 88109273.8 19-Jul-1994 00-Xxx-00
00000-000XX0 Xxxxxxx XXX Granted 89901681.0 20-Dec-1988 P3885300.0 27-Oct-1993 20-Dec-08
00000-000XX0 Xxxxxxx PCT Allowed 4122/89 20-Dec-1988
02854-010EP1 Europe PCT Granted 89901681.0 20-Dec-1988 0394349 27-Oct-1993 20-Dec-08
00000-000XX0 Xxxxxx EPC Granted 89901681.0 20-Dec-1988 0394349 27-Oct-1993 20-Dec-08
02854-010GB1 Great Britain EPC Granted 89901681.0 20-Dec-1988 0394349 27-Oct-1993 20-Dec-08
02854-010IE1 Ireland PCT Granted 3833/88 21-Dec-1988 61283 14-Oct-1994 20-Dec-08
00000-000XX0 Xxxxx EPC Granted 89901681.0 20-Dec-1988 0394349 27-Oct-1993 20-Dec-08
00000-000XX0 Xxxxx PCT Granted 501944/89 20-Dec-1988 1923551 25-Apr-1995 00-Xxx-00
00000-000XX0 Xxxxxxxxxx XXX Granted 89901681.0 20-Dec-1988 0394349 27-Oct-1993 20-Dec-08
02854-010MX1 Mexico PCT Granted 14307 22-Dec-1988 164966 09-Oct-1992 20-Dec-08
00000-000XX0 Xxxxxxxxxxx EPC Granted 89901681.0 20-Dec-1988 0394349 27-Oct-1993 20-Dec-08
02854-010NZ1 Xxx Xxxxxxx XXX Xxxxxxx 000000 21-Dec-1988 227429 14-May-1991 21-Dec-04
00000-000XX0 Xxxxxx EPC Granted 89901681.0 20-Dec-1988 0394349 27-Oct-1993 20-Dec-08
02854-010TW1 Taiwan PCT Granted 78100693 01-Feb-1989 NI-51930 20-Feb-1992 00-Xxx-00
00000-000XX0 Xxxxx Xxxxxx PCT Granted 88/9594 22-Dec-1988 88/9594 27-Sep-1989 22-Dec-08
WOUND HEALING
02854-011AT1 Austria EPC Granted 89906917.3 22-May-1989 0419534 03-Aug-1994 22-May-09
02854-011AT2 Austria EPC Granted 91910904.1 30-May-1991 0531425 14-Aug-2002 30-May-11
00000-000XX0 Xxxxxxx EPC Granted 89906917.3 22-May-1989 0419534 03-Aug-1994 22-May-09
00000-000XX0 Xxxxxxx EPC Granted 91910904.1 30-May-1991 0531425 14-Aug-2002 30-May-11
02854-011CA2 Canada PCT Granted 2,082,420 30-May-1991 2082420 20-Jul-2004 30-May-11
00000-000XX0 Xxxxxxxxxxx EPC Granted 89906917.3 22-May-1989 0419534 03-Aug-1994 22-May-09
00000-000XX0 Xxxxxxxxxxx EPC Granted 91910904.1 30-May-1991 531425 14-Aug-2002 30-May-11
00000-000XX0 Xxxxxxx EPC Granted 89906917.3 22-May-1989 P68917300.8 03-Aug-1994 22-May-09
00000-000XX0 Xxxxxxx EPC Granted 69133087.5 30-May-1991 0531425 14-Aug-2002 30-May-11
00000-000XX0 Xxxxxxx EPC Granted 91910904.1 30-May-1991 0531425 14-Aug-2002 30-May-11
02854-011EP1 Europe PCT Granted 89906917.3 22-May-1989 0419534 03-Aug-1994 22-May-09
02854-011EP2 Europe PCT Granted 91910904.1 30-May-1991 0531425 14-Aug-2002 30-May-11
00000-000XX0 Xxxxx EPC Granted 0531425 30-May-1991 0531425 14-Aug-2002 30-May-11
00000-000XX0 Xxxxxx EPC Granted 0419534 22-May-1989 0419534 03-Aug-1994 22-May-09
00000-000XX0 Xxxxxx EPC Granted 0531425 30-May-1991 0531425 14-Aug-2002 30-May-11
02854-011GB1 Great Britain EPC Granted 89906917.3 22-May-1989 0419534 03-Aug-1994 22-May-09
02854-011GB2 Great Britain EPC Granted 0531425 30-May-1991 0531425 14-Aug-2002 30-May-11
00000-000XX0 Xxxxxx EPC Granted 91910904.1 30-May-1991 0531425 14-Aug-2002 30-May-11
00000-000XX0 Xxxxx EPC Granted 89906917.3 22-May-1989 0419534 03-Aug-1994 22-May-09
00000-000XX0 Xxxxx EPC Granted 0531425 30-May-1991 0531425 14-Aug-2002 30-May-11
00000-000XX0 Xxxxx PCT Granted 506485/89 22-May-1989 1924479 25-Apr-1995 22-May-09
00000-000XX0 Xxxxx PCT Granted 3-510861 30-May-1991 3,377,524 06-Dec-2002 30-May-11
02854-011LI2 Liechtenstein EPC Granted 91910904.1 30-May-1991 531425 14-Aug-2002 30-May-11
00000-000XX0 Xxxxxxxxxx EPC Granted 89906917.3 22-May-1989 0419534 03-Aug-1994 22-May-09
00000-000XX0 Xxxxxxxxxx EPC Granted 91910904.1 30-May-1991 0531425 14-Aug-2002 30-May-11
00000-000XX0 Xxxxxxxxxxx EPC Granted 89906917.3 22-May-1989 0419534 03-Aug-1994 22-May-09
00000-000XX0 Xxxxxxxxxxx EPC Granted 91910904.1 30-May-1991 0531425 14-Aug-2002 30-May-11
00000-000XX0 Xxxxxx EPC Granted 89906917.3 22-May-1989 0419534 03-Aug-1994 22-May-09
00000-000XX0 Xxxxxx EPC Granted 91910904.1 30-May-1991 0531425 14-Aug-2002 30-May-11
WOUND HEALING
02854-012AT1 Austria EPC Granted 89910545.6 10-Aug-1989 0382841 26-Jan-1994 9-Aug-09
00000-000XX0 Xxxxxxx EPC Granted 89910545.6 10-Aug-1989 0382841 26-Jan-1994 9-Aug-09
02854-012CA1 Canada PCT Granted 607,968 10-Aug-1989 1336816 29-Aug-1995 29-Aug-12
00000-000XX0 Xxxxxxxxxxx EPC Granted 89910545.6 10-Aug-1989 0382841 26-Jan-1994 9-Aug-09
02854-012DE1 Denmark EPC Granted 89910545.6 10-Aug-1989 P68912758 26-Jan-1994 9-Aug-09
00000-000XX0 Xxxxxxx EPC Granted 89910545.6 10-Aug-1989 0382841 26-Jan-1994 9-Aug-09
02854-012EP1 Europe PCT Granted 89910545.6 10-Aug-1989 0382841 26-Jan-1994 9-Aug-09
00000-000XX0 Xxxxxx EPC Granted 89910545.6 10-Aug-1989 382841 26-Jan-1994 9-Aug-09
02854-012GB1 Great Britain EPC Granted 89910545.6 10-Aug-1989 0382841 26-Jan-1994 9-Aug-09
00000-000XX0 Xxxxx EPC Granted 89910545.6 10-Aug-1989 0382841 26-Jan-1994 9-Aug-09
00000-000XX0 Xxxxx PCT Granted 509811/89 10-Aug-1989 1975393 27-Sep-1995 10-Aug-09
00000-000XX0 Xxxxxxxxxx EPC Granted 89910545.6 10-Aug-1989 0382841 26-Jan-1994 9-Aug-09
00000-000XX0 Xxxxxxxxxxx EPC Granted 89910545.6 10-Aug-1989 0382841 26-Jan-1994 9-Aug-09
00000-000XX0 Xxxxxx EPC Granted 89910545.6 10-Aug-1989 0382841 26-Jan-1994 9-Aug-09
WOUND HEALING USING PDGF AND IGF-II
02854-014AT1 Austria EPC Granted 90907577.2 10-Apr-1990 0479799 06-Aug-1997 10-Apr-10
00000-000XX0 Xxxxxxx EPC Granted 90907577.2 10-Apr-1990 0479799 06-Aug-1997 10-Apr-10
02854-014CA1 Canada PCT Granted 2,060,208 10-Apr-1990 2,060,208 20-Feb-2001 10-Apr-10
00000-000XX0 Xxxxxxxxxxx EPC Granted 90907577.2 10-Apr-1990 0479799 06-Aug-1997 10-Apr-10
00000-000XX0 Xxxxxxx EPC Granted 90907577.2 10-Apr-1990 0479799 06-Aug-1997 00-Xxx-00
00000-000XX0 Xxxxxxx XXX Granted 90907577.2 10-Apr-1990 0479799 06-Aug-1997 10-Apr-10
02854-014EP1 Europe PCT Granted 90907577.2 10-Apr-1990 0479799 06-Aug-1997 10-Apr-10
00000-000XX0 Xxxxx EPC Granted 90907577.2 10-Apr-1990 0479799 06-Aug-1997 10-Apr-10
00000-000XX0 Xxxxxx EPC Granted 90907577.2 10-Apr-1990 0479799 06-Aug-1997 10-Apr-10
02854-014GB1 Great Britain EPC Granted 90907577.2 10-Apr-1990 0479799 06-Aug-1997 10-Apr-10
00000-000XX0 Xxxxx EPC Granted 90907577.2 10-Apr-1990 0479799 06-Aug-1997 00-Xxx-00
00000-000XX0 Xxxxx PCT Granted 507475/90 10-Apr-1990 2030420 19-Mar-1996 00-Xxx-00
00000-000XX0 Xxxxxxxxxx XXX Granted 90907577.2 10-Apr-1990 0479799 06-Aug-1997 10-Apr-10
00000-000XX0 Xxxxxxxxxxx EPC Granted 90907577.2 10-Apr-1990 0479799 06-Aug-1997 10-Apr-10
00000-000XX0 Xxxxxx EPC Granted 90907577.2 10-Apr-1990 0479799 06-Aug-1997 10-Apr-10
WOUND HEALING
02854-016CA1 Canada PCT Pending 2,040,410 07-Sep-1990
00000-000XX0 Xxxxx PCT Granted 2-512565 07-Sep-1990 1969836 18-Sep-1995 7-Sep-10
BONE REGENERATION
02854-026CA1 Canada PCT Abandoned 2,123,803 24-Nov-1992
00000-000XX0 Xxxxx PCT Abandoned Hei-05-510253 26-May-1994
02854-026EP1 Europe PCT Abandoned 93900683.9 24-Nov-1992
MEDICAMENT FOR PROMOTING GROWTH OF MAMMALIAN NERVE - IMB ONLY
02854-027AU1 Australia PCT Granted 30668/92 04-Nov-1992 673659 12-Mar-1997 4-Nov-12
02854-027CA1 Canada PCT Granted 2,123,685 04-Nov-1992 2,123,685 07-Oct-2003 0-Xxx-00
00000-000XX0 Xxxxxxxxxxx PCT Granted 2309/93-2 04-Nov-1992 684573 31-Oct-1994 0-Xxx-00
00000-000XX0 Xxxxx PCT Pending 5-510115 04-Nov-1992
PYRIDINOLINE CROSSLINKS AS MARKERS OF PERIODONTAL AND PERI-IMPLANT DISEASE ACTIVITY
02854-034AT1 Austria EPC Granted 95909234.7 13-Jan-1995 E220458 10-Jul-2002 13-Jan-15
00000-000XX0 Xxxxxxx EPC Granted 95909234.7 13-Jan-1995 0745221 10-Jul-2002 13-Jan-15
02854-034CA1 Canada PCT Pending 2,183,452 13-Jan-1995
00000-000XX0 Xxxxxxxxxxx EPC Granted 95909234.7 13-Jan-1995 0745221 10-Jul-2002 13-Jan-15
00000-000XX0 Xxxxxxx EPC Granted 95909234.7 13-Jan-1995 69527350.7 10-Jul-2002 13-Jan-15
00000-000XX0 Xxxxxxx PCT Granted 95909234.7 13-Jan-1995 0745221 07-Oct-2002 13-Jan-15
02854-034EP1 Europe PCT Granted 95909234.7 13-Jan-1995 0745221 10-Jul-2002 13-Jan-15
00000-000XX0 Xxxxx EPC Granted 95909234.7 13-Jan-1995 ES2179867T3 10-Jul-2002 13-Jan-15
00000-000XX0 Xxxxxx EPC Granted 95909234.7 13-Jan-1995 0745221 10-Jul-2002 13-Jan-15
02854-034GB1 Great Britain EPC Granted 95909234.7 13-Jan-1995 0745221 10-Jul-2002 13-Jan-15
00000-000XX0 Xxxxxx EPC Granted 95909234.7 13-Jan-1995 0745221 10-Jul-2002 13-Jan-15
02854-034IE1 Ireland PCT Granted 95909234.7 13-Jan-1995 0745221 13-Jan-15
00000-000XX0 Xxxxx EPC Granted 95909234.7 13-Jan-1995 0745221 10-Jul-2002 13-Jan-15
00000-000XX0 Xxxxx PCT Granted 7-521795 13-Jan-1995 3,521,913 20-Feb-2004 00-Xxx-00
00000-000XX0 X. Xxxxx PCT Granted 96-0594 16-Aug-1996 31,331 22-Jan-1998 13-Jan-15
00000-000XX0 Xxxxxxxxxxx EPC Granted 95909234.7 13-Jan-1995 0745221 10-Jul-2002 13-Jan-15
00000-000XX0 Xxxxxxxx EPC Granted 95909234.7 13-Jan-1995 0745221 10-Jul-2002 13-Jan-15
00000-000XX0 Xxxxxx EPC Granted 95909234.7 13-Jan-1995 0745221 10-Jul-2002 13-Jan-15
00000-000XX0 Xxxxx PCT Abandoned 95192443.5 13-Jan-1995
02854-034KR1 S. Korea PCT Abandoned 1996-704491 16-Aug-1996
PATENT EXP.
C & E REF. NO. STATUS TITLE APPLICATION NO. FILED PATENT NO. ISSUED DATE
-------------- ------ -------------------------- --------------- ----------- ---------- ----------- -----------
02854-009001 Issued WOUND HEALING AND BONE 07/120,943 16-Nov-1987 4,861,757 29-Aug-1989 29-Aug-2006
REGENERATION USING PDGF
AND IGF-1
02854-010001 Issued WOUND HEALING 07/136,399 22-Dec-1987 4,874,746 17-Oct-1989 17-Oct-2006
COMPOSITION OF TGF-ALPHA
AND PDGF
02854-011001 Issued WOUND HEALING USING IGF-I 07/196,975 20-May-1988 4,983,581 8-Jan-1991 8-Jan-2008
AND TGF'b'
02854-011003 Issued WOUND HEALING USING IGF-II 07/857,713 25-Mar-1992 5,256,644 26-Oct-1993 8-Jan-2008
AND TGF
02854-012001 Issued PROCESS OF WOUND HEALING 07/231,145 10-Aug-1988 5,034,375 23-Jul-1991 23-Jul-2008
USING PDGF AND EGF
02854-014001 Issued WOUND HEALING USING PDGF 07/272,090 16-Nov-1988 5,019,559 28-May-1991 28-May-2008
AND IGF-II
02854-015002 Issued METHOD OF PERIDONTAL 07/582,332 13-Sep-1990 5,124,316 23-Jun-1992 23-Jul-2009
REGENERATION
02854-016001 Issued WOUND HEALING COMPOSITION 07/403,969 7-Sep-1989 5,035,887 30-Jul-1991 30-Jul-2008
OF IL-1 AND PDGF OR IGF-1
02854-027001 Issued NERVE REGENERATION 08/198,542 18-Feb-1994 6,506,727 14-Jan-2003 14-Jan-2020
02854-033001 Issued DEVICE TO PROMOTE DRUG- 08/187,210 26-Jan-1994 5,656,605 12-Aug-1997 12-Aug-2014
INDUCED NERVE
REGENERATION
02854-034001 Issued PYRIDINOLINE CROSSLINKS 08/197,131 16-Feb-1994 5,516,699 14-May-1996 14-May-2013
AS MARKERS OF PERIODONTAL
AND PERI-IMPLANT DISEASE
ACTIVITY
ASSIGNMENT
For valuable consideration, we,
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State (and Country if
Full Name of Assignor City not USA)
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Institute of Molecular Delaware P.O. Box 4278
Biology, Inc. Xxxxxxxxxx, XX 00000
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hereby assign to
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Full Name of Assignee State of Incorporation Business Address
--------------------------------------------------------------------------------
BioMimetic Therapeutics, Inc. Delaware 000 Xxxxxx Xxxx Xxxx
Xxxxxxxx, XX 00000
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and to its successors and assigns (collectively hereinafter called "the
Assignee"), the entire right, title, and interest throughout the world in the
inventions and improvements which are the subject of one or more of the patents
and applications listed on Schedule A, which is attached hereto.
This assignment includes the patents and applications listed in the attached
Schedule A, any and all United States and foreign patents, utility models, and
design registrations granted for any of said inventions or improvements, and the
right to claim priority based on the filing date of any of the patents and
applications listed in the attached Schedule A under the International
Convention for the Protection of Industrial Property, the Patent Cooperation
Treaty, the European Patent Convention, and all other treaties of like purposes;
and we authorize the Assignee to apply in all countries in our names or in its
own name for patents, utility models, design registrations, and like rights of
exclusion, and for inventors' certificates for said inventions and improvements;
and we agree for ourselves and our respective heirs, legal representatives and
assigns, without further compensation, to perform such lawful acts and to sign
such further applications, assignments, Preliminary Statements, and other lawful
documents as the Assignee may reasonably request to effectuate fully this
assignment.
IN WITNESS WHEREOF, I hereto set my hand and seal at Shrewsbury Massachusetts,
this 4th day of November, 2005.
/s/ Xxxx X. Xxxxxx L.S.
------------------------------------
Xxxx X. Xxxxxx
Institute of Molecular Biology, Inc.
STATE OF MASSACHUSETTS:
:ss.
COUNTY OF WORCESTER:
Before me this 4th day of November, 2005, before me, the undersigned notary
public, personally appeared Xxxx X. Xxxxxx, proved to me through satisfactory
evidence of identification, which consisted of Massachusetts Driver's License,
to be the person whose name is subscribed to the foregoing Assignment, and
acknowledged that he executed the same as his free act and deed for the purposes
therein contained.
/s/ Xxxxxxxx XxxXxxxx
------------------------------
Notary Public
My Commission Expires: 020708
[Notary Seal]
SCHEDULE A
(PAGE 1 OF 5)
C & E REF. NO. STATUS TITLE APPLICATION NO. FILED PATENT NO. ISSUED
-------------- --------- -------------------------- --------------- ----------- ----------- -----------
WOUND HEALING AND BONE
02854-007001 Abandoned REGENERATION 06/930,762 14-Nov-1986
WOUND HEALING AND BONE
REGENERATION USING PDGF
02854-009001 Issued AND IGF-1 07/120,943 16-Nov-1987 4,861,757 29-Aug-1989
WOUND HEALING
COMPOSITION OF TGF-ALPHA
02854-010001 Issued AND PDGF 07/136,399 22-Dec-1987 4,874,746 17-Oct-1989
WOUND HEALING USING IGF-I
02854-011001 Issued AND TGF'b' 07/196,975 20-May-1988 4,983,581 8-Jan-1991
WOUND HEALING USING IGF-I
02854-011002 Abandoned AND TGF'b' 07/530,649 30-May-1990
WOUND HEALING USING IGF-II
02854-011003 Issued AND TGF 07/857,713 25-Mar-1992 5,256,644 26-Oct-1993
PROCESS OF WOUND HEALING
02854-012001 Issued USING PDGF AND EGF 07/231,145 10-Aug-1988 5,034,375 23-Jul-1991
02854-013003 Abandoned WOUND HEALING 07/449,303 5-Dec-1989
02854-013004 Abandoned WOUND HEALING 07/639,060,303 9-Jan-1991
WOUND HEALING USING PDGF
02854-014001 Issued AND IGF-II 07/272,090 16-Nov-1988 5,019,559 28-May-1991
02854-015001 Abandoned WOUND HEALING 07/299,763 23-Jan-1989
METHOD OF PERIDONTAL
02854-015002 Issued REGENERATION 07/582,332 13-Sep-1990 5,124,316 23-Jun-1992
WOUND HEALING
COMPOSITION OF IL-1 AND
02854-016001 Issued PDGF OR IGF-1 07/403,969 7-Sep-1989 5,035,887 30-Jul-1991
02854-026001 Abandoned BONE REGENERATION 07/799,375 27-Nov-1991
02854-027001 Issued NERVE REGENERATION 08/198,542 18-Feb-1994 6,506,727 14-Jan-2003
DEVICE TO PROMOTE DRUG-
INDUCED NERVE
02854-033001 Issued REGENERATION 08/187,210 26-Jan-1994 5,656,605 12-Aug-1997
PYRIDINOLINE CROSSLINKS AS
MARKERS OF PERIODONTAL
AND PERI-IMPLANT DISEASE
02854-034001 Issued ACTIVITY 08/197,131 16-Feb-1994 5,516,699 14-May-1996
SCHEDULE A
(PAGE 2 OF 5)
C & E REF. NO. COUNTRY TYPE STATUS APPLICATION NO. FILED PATENT NO. ISSUED
-------------- ------------- ---- --------- --------------- ----------- ----------- -----------
WOUND HEALING AND BONE REGENERATION
02854-007AT 1 Austria EPC Granted 87907900.2 13-Nov-1987 0289584 05-May-1993
02854-007AU1 Australia PCT Granted 83289/87 13-Nov-1987 600069 02-Aug-1990
00000-000XX0 Xxxxxxx EPC Granted 87907900.2 13-Nov-1987 0289584 05-May-1993
02854-007CA1 Canada PCT Granted 551,909 16-Nov-1987 1,322,714 05-Oct-1993
00000-000XX0 Xxxxxxxxxxx EPC Granted 87907900.2 13-Nov-1987 0289584 05-May-1993
00000-000XX0 Xxxxx PCT Granted 87101250.2 14-Nov-1987 87101250.2 30-Oct-1994
00000-000XX0 Xxxxxxx EPC Granted 87907900.2 13-Nov-1987 0289584 05-May-1993
00000-000XX0 Xxxxxxx PCT Granted 3932/88 13-Nov-1987 25-Jul-81 30-May-05
02854-007EP1 Europe PCT Granted 87907900.2 13-Nov-1987 0289584 05-May-1993
00000-000XX0 Xxxxxx EPC Granted 87907900.2 13-Nov-1987 0289584 05-May-1993
00000-000XX0 Xxxxxx EPC Granted 89906917.3 22-May-1989 0419534 03-Aug-1994
02854-007GB1 Great Britain EPC Granted 87907900.2 13-Nov-1987 0289584 05-May-1993
02854-007IE1 Ireland PCT Granted 3075/87 13-Nov-1987 60517 20-Jul-1994
00000-000XX0 Xxxxx EPC Granted 87907900.2 13-Nov-1987 0289584 05-May-1993
00000-000XX0 Xxxxx PCT Granted 500179/87 13-Nov-1987 1868245 26-Aug-1994
02854-007KR1 Korea PCT Granted 88-700829 13-Nov-1987 106280 17-Oct-1996
00000-000XX0 Xxxxxxxxxx EPC Granted 87907900.2 13-Nov-1987 0289584 05-May-1993
00000-000XX0 Xxxxxxxxxxx EPC Granted 87907900.2 13-Nov-1987 0289584 05-May-1993
02854-007NZ1 Xxx Xxxxxxx XXX Xxxxxxx 000000 16-Nov-1987 222551
00000-000XX0 Xxxxxx EPC Granted 87907900.2 13-Nov-1987 0289584 05-May-1993
02854-007TW1 Taiwan PCT Granted 76107672 15-Dec-1987 NI-51493 30-Jan-1992
00000-000XX0 Xxxxx Xxxxxx PCT Granted 87/8566 16-Nov-1987 87/8566 26-Jul-1989
02854-007OA1 Africa (OAPI) PCT Abandoned PV59385 13-Nov-1987 9159 31-Mar-1992
02854-007MX1 Mexico PCT Abandoned 930672 16-Nov-1987 170454 23-Aug-1993
00000-000XX0 Xxxxxx PCT Abandoned 88/3127 13-Nov-1987
02854-007WO1 International PCT Expired PCT/US87/02975 13-Nov-1987
WOUND HEALING
02854-010AT1 Austria EPC Granted 89901681.0 20-Dec-1988 0394349 27-Oct-1993
02854-010AU1 Australia PCT Granted 37472/89 20-Dec-1988 613776 03-Dec-1991
00000-000XX0 Xxxxxxx EPC Granted 89901681.0 20-Dec-1988 0394349 27-Oct-1993
02854-010CA1 Canada PCT Granted 586,562 21-Dec-1988 1,322,164 14-Sep-1993
00000-000XX0 Xxxxxxxxxxx EPC Granted 89901681.0 20-Dec-1988 0394349 27-Oct-1993
00000-000XX0 Xxxxx PCT Granted 88109273.8 21-Dec-1988 88109273.8 19-Jul-1994
00000-000XX0 Xxxxxxx EPC Granted 89901681.0 20-Dec-1988 P3885300.0 27-Oct-1993
00000-000XX0 Xxxxxxx PCT Granted 4122/89 20-Dec-1988 175947 08-Aug-2005
02854-010EP1 Europe PCT Granted 89901681.0 20-Dec-1988 0394349 27-Oct-1993
00000-000XX0 Xxxxxx EPC Granted 89901681.0 20-Dec-1988 0394349 27-Oct-1993
02854-010GB1 Great Britain EPC Granted 89901681.0 20-Dec-1988 0394349 27-Oct-1993
00000-000XX0 Xxxxxxx PCT Granted 3833/88 21-Dec-1988 61283 14-Oct-1994
00000-000XX0 Xxxxx EPC Granted 89901681.0 20-Dec-1988 0394349 27-Oct-1993
00000-000XX0 Xxxxx PCT Granted 501944/89 20-Dec-1988 1923551 25-Apr-1995
00000-000XX0 Xxxxxxxxxx EPC Granted 89901681.0 20-Dec-1988 0394349 27-Oct-1993
02854-010MX1 Mexico PCT Granted 14307 22-Dec-1988 164966 09-Oct-1992
00000-000XX0 Xxxxxxxxxxx EPC Granted 89901681.0 20-Dec-1988 0394349 27-Oct-1993
02854-010NZ1 Xxx Xxxxxxx XXX Xxxxxxx 000000 21-Dec-1988 227429 14-May-1991
00000-000XX0 Xxxxxx EPC Granted 89901681.0 20-Dec-1988 0394349 27-Oct-1993
02854-010TW1 Taiwan PCT Granted 78100693 01-Feb-1989 NI-51930 20-Feb-1992
00000-000XX0 Xxxxx Xxxxxx PCT Granted 88/9594 22-Dec-1988 88/9594 27-Sep-1989
02854-010OA1 Africa (OAPI) PCT Abandoned PV59630 20-Dec-1988 9129 31-Oct-1991
02854-010KR1 Korea PCT Abandoned 89/701555 20-Dec-1988
00000-000XX0 Xxxxxx PCT Abandoned 89/3346 20-Dec-1988
02854-010RU1 Russian PCT Abandoned 4742130.14 20-Dec-1988
Federation
02854-010WO1 International PCT Expired PCT/US88/04557 20-Dec-1988
SCHEDULE A
(PAGE 3 OF 5)
C & E REF. NO. COUNTRY TYPE STATUS APPLICATION NO. FILED PATENT NO. ISSUED
-------------- ------------- ---- --------- --------------- ----------- ----------- -----------
WOUND HEALING
02854-011AT1 Austria EPC Granted 89906917.3 22-May-1989 0419534 03-Aug-1994
02854-011AT2 Austria EPC Granted 91910904.1 30-May-1991 0531425 14-Aug-2002
00000-000XX0 Xxxxxxx EPC Granted 89906917.3 22-May-1989 0419534 03-Aug-1994
00000-000XX0 Xxxxxxx EPC Granted 91910904.1 30-May-1991 0531425 14-Aug-2002
02854-011CA2 Canada PCT Granted 2,082,420 30-May-1991 2082420 20-Jul-2004
00000-000XX0 Xxxxxxxxxxx EPC Granted 89906917.3 22-May-1989 0419534 03-Aug-1994
00000-000XX0 Xxxxxxxxxxx EPC Granted 91910904.1 30-May-1991 531425 14-Aug-2002
00000-000XX0 Xxxxxxx EPC Granted 89906917.3 22-May-1989 P68917300.8 03-Aug-1994
00000-000XX0 Xxxxxxx EPC Granted 69133087.5 30-May-1991 0531425 14-Aug-2002
00000-000XX0 Xxxxxxx EPC Granted 91910904.1 30-May-1991 0531425 14-Aug-2002
02854-011EP1 Europe PCT Granted 89906917.3 22-May-1989 0419534 03-Aug-1994
02854-011EP2 Europe PCT Granted 91910904.1 30-May-1991 0531425 14-Aug-2002
00000-000XX0 Xxxxx EPC Granted 0531425 30-May-1991 0531425 14-Aug-2002
00000-000XX0 Xxxxxx EPC Granted 0419534 22-May-1989 0419534 03-Aug-1994
00000-000XX0 Xxxxxx EPC Granted 0531425 30-May-1991 0531425 14-Aug-2002
02854-011GB1 Great Britain EPC Granted 89906917.3 22-May-1989 0419534 03-Aug-1994
02854-011GB2 Great Britain EPC Granted 0531425 30-May-1991 0531425 14-Aug-2002
00000-000XX0 Xxxxxx EPC Granted 91910904.1 30-May-1991 0531425 14-Aug-2002
00000-000XX0 Xxxxx EPC Granted 89906917.3 22-May-1989 0419534 03-Aug-1994
00000-000XX0 Xxxxx EPC Granted 0531425 30-May-1991 0531425 14-Aug-2002
00000-000XX0 Xxxxx PCT Granted 506485/89 22-May-1989 1924479 25-Apr-1995
00000-000XX0 Xxxxx PCT Granted 3-510861 30-May-1991 3,377,524 06-Dec-2002
02854-011LI2 Liechtenstein EPC Granted 91910904.1 30-May-1991 531425 14-Aug-2002
00000-000XX0 Xxxxxxxxxx EPC Granted 89906917.3 22-May-1989 0419534 03-Aug-1994
00000-000XX0 Xxxxxxxxxx EPC Granted 91910904.1 30-May-1991 0531425 14-Aug-2002
00000-000XX0 Xxxxxxxxxxx EPC Granted 89906917.3 22-May-1989 0419534 03-Aug-1994
00000-000XX0 Xxxxxxxxxxx EPC Granted 91910904.1 30-May-1991 0531425 14-Aug-2002
00000-000XX0 Xxxxxx EPC Granted 89906917.3 22-May-1989 0419534 03-Aug-1994
00000-000XX0 Xxxxxx EPC Granted 91910904.1 30-May-1991 0531425 14-Aug-2002
00000-000XX0 Xxxxx PCT Abandoned 531425 30-May-1991
02854-011WO1 International PCT Expired PCT/US89/02229 22-May-1989
02854-011WO2 International PCT Expired PCT/US91/03829 30-May-1991
WOUND HEALING
02854-012AT1 Austria EPC Granted 89910545.6 10-Aug-1989 0382841 26-Jan-1994
00000-000XX0 Xxxxxxx EPC Granted 89910545.6 10-Aug-1989 0382841 26-Jan-1994
02854-012CA1 Canada PCT Granted 607,968 10-Aug-1989 1336816 29-Aug-1995
00000-000XX0 Xxxxxxxxxxx EPC Granted 89910545.6 10-Aug-1989 0382841 26-Jan-1994
00000-000XX0 Xxxxxxx EPC Granted 89910545.6 10-Aug-1989 P68912758 26-Jan-1994
00000-000XX0 Xxxxxxx EPC Granted 89910545.6 10-Aug-1989 0382841 26-Jan-1994
02854-012EP1 Europe PCT Granted 89910545.6 10-Aug-1989 0382841 26-Jan-1994
00000-000XX0 Xxxxxx EPC Granted 89910545.6 10-Aug-1989 382841 26-Jan-1994
02854-012GB1 Great Britain EPC Granted 89910545.6 10-Aug-1989 0382841 26-Jan-1994
00000-000XX0 Xxxxx EPC Granted 89910545.6 10-Aug-1989 0382841 26-Jan-1994
00000-000XX0 Xxxxx PCT Granted 509811/89 10-Aug-1989 1975393 27-Sep-1995
00000-000XX0 Xxxxxxxxxx EPC Granted 89910545.6 10-Aug-1989 0382841 26-Jan-1994
00000-000XX0 Xxxxxxxxxxx EPC Granted 89910545.6 10-Aug-1989 0382841 26-Jan-1994
00000-000XX0 Xxxxxx EPC Granted 89910545.6 10-Aug-1989 0382841 26-Jan-1994
02854-012WO1 International PCT Expired PCT/US89/03490 10-Aug-1989
SCHEDULE A
(PAGE 4 OF 5)
C & E REF. NO. COUNTRY TYPE STATUS APPLICATION NO. FILED PATENT NO. ISSUED
-------------- ------------- ---- --------- --------------- ----------- ----------- -----------
WOUND HEALING USING PDGF AND IGF-II
02854-014AT1 Austria EPC Granted 90907577.2 10-Apr-1990 0479799 06-Aug-1997
00000-000XX0 Xxxxxxx EPC Granted 90907577.2 10-Apr-1990 0479799 06-Aug-1997
02854-014CA1 Canada PCT Granted 2,060,208 10-Apr-1990 2,060,208 20-Feb-2001
00000-000XX0 Xxxxxxxxxxx EPC Granted 90907577.2 10-Apr-1990 0479799 06-Aug-1997
00000-000XX0 Xxxxxxx EPC Granted 90907577.2 10-Apr-1990 0479799 06-Aug-1997
00000-000XX0 Xxxxxxx EPC Granted 90907577.2 10-Apr-1990 0479799 06-Aug-1997
02854-014EP1 Europe PCT Granted 90907577.2 10-Apr-1990 0479799 06-Aug-1997
00000-000XX0 Xxxxx EPC Granted 90907577.2 10-Apr-1990 0479799 06-Aug-1997
00000-000XX0 Xxxxxx EPC Granted 90907577.2 10-Apr-1990 0479799 06-Aug-1997
02854-014GB1 Great Britain EPC Granted 90907577.2 10-Apr-1990 0479799 06-Aug-1997
00000-000XX0 Xxxxx EPC Granted 90907577.2 10-Apr-1990 0479799 06-Aug-1997
00000-000XX0 Xxxxx PCT Granted 507475/90 10-Apr-1990 2030420 19-Mar-1996
00000-000XX0 Xxxxxxxxxx EPC Granted 90907577.2 10-Apr-1990 0479799 06-Aug-1997
00000-000XX0 Xxxxxxxxxxx EPC Granted 90907577.2 10-Apr-1990 0479799 06-Aug-1997
00000-000XX0 Xxxxxx EPC Granted 90907577.2 10-Apr-1990 0479799 06-Aug-1997
02854-014WO1 International PCT Expired PCT/US90/01936 10-Apr-1990
WOUND HEALING
02854-016CA1 CANADA PCT PENDING 2,040,410 07-SEP-1990
00000-000XX0 Xxxxx PCT Granted 2-512565 07-Sep-1990 1969836 18-Sep-1995
02854-016EP1 Europe PCT Abandoned 90913582.4 07-Sep-1990
02854-016WO1 International PCT Expired PCT/US90/05062 07-Sep-1990
BONE REGENERATION
02854-026CA1 Canada PCT Abandoned 2,123,803 24-Nov-1992
00000-000XX0 Xxxxx PCT Abandoned Hei-05-510253 26-May-1994
02854-026EP1 Europe PCT Abandoned 93900683.9 24-Nov-1992
02854-026WO1 International PCT Expired PCT/US92/10214 24-Nov-1992
MEDICAMENT FOR PROMOTING GROWTH OF MAMMALIAN NERVE - IMB ONLY
02854-027AU1 Australia PCT Granted 30668/92 04-Nov-1992 673659 12-Mar-1997
02854-027CA1 Canada PCT Granted 2,123,685 04-Nov-1992 2,123,685 07-Oct-2003
00000-000XX0 Xxxxxxxxxxx PCT Granted 2309/93-2 04-Nov-1992 684573 31-Oct-1994
00000-000XX0 Xxxxx PCT Allowed 5-510115 04-Nov-1992
00000-000XX0 Xxxxx PCT Pending 2005-292267 28-Sep-2005
02854-027EP1 Europe PCT Abandoned 92924312.9 04-Nov-1992
02854-027PL1 Poland PCT Abandoned P303981 04-Nov-1992
00000-000XX0 Xxxxx Xxxxxx PCT Abandoned 04-Nov-1992
02854-027WO1 International PCT Expired PCT/US92/09545 04-Nov-1992
SCHEDULE A
(PAGE 5 OF 5)
C & E REF. NO. COUNTRY TYPE STATUS APPLICATION NO. FILED PATENT NO. ISSUED
-------------- ------------- ---- --------- --------------- ----------- ----------- -----------
A DEVICE TO PROMOTE DRUG-INDUCED NERVE REGENERATION
02854-033WO1 International PCT Expired PCT/US95/00985 25-Jan-1995
PYRIDINOLINE CROSSLINKS AS MARKERS OF PERIODONTAL
AND PERI-IMPLANT DISEASE ACTIVITY
02854-034AT1 Austria EPC Granted 95909234.7 13-Jan-1995 E220458 10-Jul-2002
00000-000XX0 Xxxxxxx EPC Granted 95909234.7 13-Jan-1995 0745221 10-Jul-2002
02854-034CA1 CANADA PCT PENDING 2,183,452 13-JAN-1995
00000-000XX0 Xxxxxxxxxxx EPC Granted 95909234.7 13-Jan-1995 0745221 10-Jul-2002
00000-000XX0 Xxxxxxx EPC Granted 95909234.7 13-Jan-1995 69527350.7 10-Jul-2002
00000-000XX0 Xxxxxxx PCT Granted 95909234.7 13-Jan-1995 0745221 07-Oct-2002
02854-034EP1 Europe PCT Granted 95909234.7 13-Jan-1995 0745221 10-Jul-2002
00000-000XX0 Xxxxx EPC Granted 95909234.7 13-Jan-1995 ES2179867T3 10-Jul-2002
00000-000XX0 Xxxxxx EPC Granted 95909234.7 13-Jan-1995 0745221 10-Jul-2002
02854-034GB1 Great Britain EPC Granted 95909234.7 13-Jan-1995 0745221 10-Jul-2002
00000-000XX0 Xxxxxx EPC Granted 95909234.7 13-Jan-1995 0745221 10-Jul-2002
02854-034IE1 Ireland PCT Granted 95909234.7 13-Jan-1995 0745221
00000-000XX0 Xxxxx EPC Granted 95909234.7 13-Jan-1995 0745221 10-Jul-2002
00000-000XX0 Xxxxx PCT Granted 7-521795 13-Jan-1995 3,521,913 20-Feb-2004
02854-034KP1 N. Korea PCT Granted 96-0594 16-Aug-1996 31,331 22-Jan-1998
00000-000XX0 Xxxxxxxxxxx EPC Granted 95909234.7 13-Jan-1995 0745221 10-Jul-2002
00000-000XX0 Xxxxxxxx EPC Granted 95909234.7 13-Jan-1995 0745221 10-Jul-2002
00000-000XX0 Xxxxxx EPC Granted 95909234.7 13-Jan-1995 0745221 10-Jul-2002
00000-000XX0 Xxxxx PCT Abandoned 95192443.5 13-Jan-1995
02854-034KR1 S. Korea PCT Abandoned 1996-704491 16-Aug-1996
02854-034WO1 International PCT Expired PCT/US95/00509 13-Jan-1995
INSTITUTE OF MOLECULAR BIOLOGY, INC.
SECRETARY'S CERTIFICATE
The undersigned, Xxxx X. Xxxxxx, the duly qualified and elected Secretary
of Institute of Molecular Biology, Inc., a Delaware corporation (the "Company"),
does hereby certify in his capacity as Secretary of the Company that:
1. Attached to this certificate as Exhibits A and B, respectively, are
true, correct and complete copies of resolutions duly adopted by the Board of
Directors of the Company on November 4, 2005, and by the stockholders of the
Company on November 4, 2005. Such resolutions have not been amended, modified,
altered, repealed or rescinded and are in full force and effect on the date
hereof; and such resolutions are the only resolutions adopted by the Board of
Directors of the Company, and by the stockholders of the Company, relating to
the matters referred to therein.
2. Attached to this certificate as Exhibit C is a certificate of good
standing of the Company issued by the Secretary of State of the State of
Delaware.
IN WITNESS WHEREOF, the undersigned hereby certifies the above to be true
and has executed this Certificate as of the 15th day of November, 2005.
/s/ Xxxx X. Xxxxxx
----------------------------
Xxxx X. Xxxxxx, Secretary
EXHIBIT A
RESOLUTIONS OF THE BOARD OF DIRECTORS
APPROVAL OF IP PORTFOLIO SALE
RESOLVED: That this Board of Directors declares the sale of the IP Portfolio
to Purchaser to be advisable and in the best interests of the
Corporation, and does hereby direct that said sale of the IP
Portfolio be presented for the approval of the stockholders of the
Corporation either by written consent or at a special meeting of the
stockholders to be called for such purpose.
APPROVAL OF PATENT PURCHASE AGREEMENT AND EXHIBITS
RESOLVED: That the form, terms and provisions of the Patent Purchase Agreement
substantially in the form attached hereto as Exhibit A (the
"Purchase Agreement"), along with any ancillary agreements or
instruments delivered by the Corporation in connection therewith
(collectively, the "Ancillary Agreements"), and the transactions
contemplated thereby be, and they hereby are, ratified and approved;
and that the execution, delivery and performance of the Purchase
Agreement and the Ancillary Documents, in the name and on behalf of
the Corporation, by the President, any Vice President, and the
Treasurer of this Corporation at the time in office (the "Authorized
Officers"), each acting singly, is hereby ratified, authorized, and
approved, with such additions, deletions and changes as the
Authorized Officer so acting may by his execution approve; the
execution and delivery of the Purchase Agreement and the Ancillary
Agreements to be conclusive evidence that the same have been
authorized and approved by the Directors of the Corporation; and
further
RESOLVED: That the Authorized Officers be, and they hereby are and each of
them singly hereby is, authorized, directed and empowered, from time
to time, in the name and on behalf of the Corporation, to execute,
make oath to, acknowledge and deliver, or cause to be executed,
acknowledged and delivered, under the seal of the Corporation if so
desired, all such other and further documents, instruments, orders,
directions, certificates, receipts, forms and other papers or
instruments, and to perform or cause to be performed all such other
and further acts, as the officer or officers so acting may in his,
her or their absolute discretion approve in connection with the
consummation of the transactions contemplated by the Purchase
Agreement or the Ancillary Agreements or for the purpose of carrying
out the intent and purpose thereof or the execution, acknowledgment
or delivery thereof or the taking of any such action to be
conclusive evidence that the same has been authorized and approved
by this Board of Directors.
EXHIBIT B
RESOLUTIONS OF THE STOCKHOLDERS
APPROVAL OF IP PORTFOLIO SALE
RESOLVED: That the sale of the IP Portfolio to Purchaser is hereby authorized,
approved and ratified.
APPROVAL OF PATENT PURCHASE AGREEMENT AND EXHIBITS
RESOLVED: That the form, terms and provisions of the Patent Purchase Agreement
substantially in the form attached hereto as Exhibit A (the
"Purchase Agreement"), along with any ancillary agreements or
instruments delivered by the Corporation in connection therewith
(collectively, the "Ancillary Agreements"), and the transactions
contemplated thereby be, and they hereby are, ratified and approved;
and that the execution, delivery and performance of the Purchase
Agreement and the Ancillary Documents, in the name and on behalf of
the Corporation, by the President, any Vice President, and the
Treasurer of this Corporation at the time in office (the "Authorized
Officers"), each acting singly, is hereby ratified, authorized, and
approved, with such additions, deletions and changes as the
Authorized Officer so acting may by his execution approve; the
execution and delivery of the Purchase Agreement and the Ancillary
Agreements to be conclusive evidence that the same have been
authorized and approved by the stockholders of the Corporation; and
further
RESOLVED: That the Authorized Officers be, and they hereby are and each of
them singly hereby is, authorized, directed and empowered, from time
to time, in the name and on behalf of the Corporation, to execute,
make oath to, acknowledge and deliver, or cause to be executed,
acknowledged and delivered, under the seal of the Corporation if so
desired, all such other and further documents, instruments, orders,
directions, certificates, receipts, forms and other papers or
instruments, and to perform or cause to be performed all such other
and further acts, as the officer or officers so acting may in his,
her or their absolute discretion approve in connection with the
consummation of the transactions contemplated by the Purchase
Agreement or the Ancillary Agreements or for the purpose of carrying
out the intent and purpose thereof or the execution, acknowledgment
or delivery thereof or the taking of any such action to be
conclusive evidence that the same has been authorized and approved
by the stockholders of the Corporation.
EXHIBIT C
CERTIFICATE OF GOOD STANDING
(see attached)
PAGE 1
Delaware
---------------
The First State
I, XXXXXXX XXXXX WINDSOR, SECRETARY OF STATE OF THE STATE OF DELAWARE, DO
HEREBY CERTIFY "INSTITUTE OF MOLECULAR BIOLOGY, INC." IS DULY INCORPORATED UNDER
THE LAWS OF THE STATE OF DELAWARE AND IS IN GOOD STANDING AND HAS A LEGAL
CORPORATE EXISTENCE SO FAR AS THE RECORDS OF THIS OFFICE SHOW, AS OF THE FOURTH
DAY OF NOVEMBER, A.D. 2005.
AND I DO HEREBY FURTHER CERTIFY THAT THE FRANCHISE TAXES HAVE BEEN PAID TO
DATE.
AND I DO HEREBY FURTHER CERTIFY THAT THE ANNUAL REPORTS HAVE BEEN FILED TO
DATE.
AND I DO HEREBY FURTHER CERTIFY THAT THE SAID "INSTITUTE OF MOLECULAR
BIOLOGY, INC." WAS INCORPORATED ON THE SIXTEENTH DAY OF JANUARY, A.D. 1985.
[SEAL]
/s/ Xxxxxxx Xxxxx Windsor
-----------------------------------------
Xxxxxxx Xxxxx Windsor, Secretary of State
2052940 8300 AUTHENTICATION: 4277347
050905116 DATE: 11-04-05
