[EXHIBIT 99.1.4]
June 30, 1999
Xxxxxx-Xxxxxxx Company
000 Xxxxx Xxxx
Xxxxxx Xxxxxx, Xxx Xxxxxx 00000
Re: Second Amendment to Collaboration Agreement
Dear Sirs/Madam:
Pfizer Inc. ("Pfizer") and Xxxxxx-Xxxxxxx Company ("Xxxxxx-Xxxxxxx")
entered into a Collaboration Agreement, effective as of June 28, 1996, as
amended by a First Amendment to Collaboration Agreement, dated February 28,
1997 (as amended, the "Collaboration Agreement"). The parties wish to
further amend the Collaboration Agreement regarding detailing to be
performed by Pfizer. Accordingly, Section 2.02 of the Collaboration
Agreement is hereby amended to insert the following new subsection (i):
"(i) Commencing May 1, 1999 and continuing until the end of Agreement
Year Five, PFIZER agrees that in discharge of its detailing
obligations as specified in this Section 2.02, PFIZER shall
utilize its Xxxxx sales force."
Except as specifically amended herein, the Collaboration Agreement
shall remain in full force and effect according to its terms. Please
indicate your agreement to this Second Amendment by signing below and
returning an original to us.
Very truly yours,
PFIZER INC.
By: /s/ Xxxx X. Xxxxxxx
------------------------------------
Name: Xxxx X. Xxxxxxx
Title: Vice President, Pfizer Inc.;
Senior Vice President
Product Development,
Pfizer Pharmaceutical Group
AGREED AND ACCEPTED:
XXXXXX-XXXXXXX COMPANY
By: /s/ Xxxxxxx Wild
-----------------------------
Name: XXXXXXX WILD
Title: Executive Vice President