GTx, Inc. UNAUDITED PRO FORMA FINANCIAL INFORMATION

EXHIBIT 99.2

GTx, Inc.

UNAUDITED PRO FORMA FINANCIAL INFORMATION

On September 28, 2012, GTx, Inc. (the “Company”) entered into an Asset Purchase Agreement (the “Purchase Agreement”) with Strakan International S.à ▇.▇. , an affiliate of ProStrakan Group plc (the “Purchaser”), pursuant to which the Company agreed to transfer, sell and assign to the Purchaser all of the Company’s rights to the metastatic breast cancer product, FARESTON^®, and certain assets related thereto (collectively, the “FARESTON^® Assets”). Effective as of September 30, 2012, the Company completed the sale of the FARESTON^® Assets pursuant to the Purchase Agreement for a total cash purchase price of approximately $21.67 million, including payment for purchased inventory. The Company estimates that it will realize net proceeds of approximately $19.0 million after expenses related to the sale of the FARESTON^® Assets (such sale, the “Disposition”).

The following unaudited pro forma financial information is presented to illustrate the effect of the Disposition on its historical financial position and operating results. The unaudited pro forma balance sheet as of June 30, 2012 is based on the historical balance sheet of the Company as of June 30, 2012 after giving effect to the Disposition as if the Disposition had occurred on June 30, 2012. The unaudited pro forma statements of operations for the six months ended June 30, 2012 and 2011 and the years ended December 31, 2011, 2010, and 2009 are based on the historical statements of operations of the Company after giving effect to the Disposition as if the Disposition had occurred on January 1, 2009. The unaudited pro forma financial statements should be read in conjunction with the Company’s historical financial statements and notes thereto contained in the Company’s 2011 Annual Report on Form 10-K, filed with the SEC on March 2, 2012 and the Company’s Quarterly Report on Form 10-Q for the quarter ended June 30, 2012, filed with the SEC on August 8, 2012.

The unaudited pro forma adjustments are based on available preliminary information and certain assumptions that the Company believes are reasonable under the circumstances. The unaudited pro forma financial information is presented for illustration purposes only, in accordance with the adjustments and estimates set forth below, and are not necessarily indicative of the results that might have occurred had the Disposition taken place on June 30, 2012 for balance sheet purposes, or on January 1, 2009 for statement of operations purposes, and are not necessarily indicative of future operating results or financial position of the Company. Actual amounts could differ materially from these estimates. All pro forma adjustments and their underlying assumptions are described more fully in the notes to the unaudited pro forma financial information.

GTx, Inc.

UNAUDITED PRO FORMA CONDENSED BALANCE SHEETS

AS OF JUNE 30, 2012

(in thousands, except share data)

		As Reported				Pro Forma				Pro Forma
		June 30, 2012				Adjustments				June 30, 2012
ASSETS
Current assets:
Cash and cash equivalents		$	47,319			$	21,671	(a)		$	68,990
Short-term investments			8,610				—				8,610
Accounts receivable, net			908				—				908
Inventory			105				(105	)(b)			—
Prepaid expenses and other current assets			1,223				—				1,223
Total current assets			58,165				21,566				79,731
Property and equipment, net			779				—				779
Intangible and other assets, net			201				—				201
Total assets		$	59,145			$	21,566			$	80,711
LIABILITIES AND STOCKHOLDERS’ EQUITY
Current liabilities:
Accounts payable		$	1,462			$	—			$	1,462
Accrued expenses and other current liabilities			5,732				2,800	(b)			8,532
Total current liabilities			7,194				2,800				9,994
Other long-term liabilities			262				—				262
Commitments and contingencies
Stockholders’ equity:
Common stock, $0.001 par value: 120,000,000 shares authorized at both June 30, 2012 and December 31, 2011; 62,809,673 and 62,790,223 shares issued and outstanding at June 30, 2012 and December 31, 2011, respectively			63				—				63
Additional paid-in capital			459,261				—				459,261
Accumulated deficit			(407,635	)			18,766	(b)			(388,869	)
Total stockholders’ equity			51,689				18,766				70,455
Total liabilities and stockholders’ equity		$	59,145			$	21,566			$	80,711

See accompanying notes to the unaudited pro forma financial statements.

F-2

GTx, Inc.

UNAUDITED PRO FORMA CONDENSED STATEMENT OF OPERATIONS

FOR THE SIX MONTHS ENDED JUNE 30, 2012

(in thousands, except share and per share data)

		As Reported								Pro Forma
		Six Months Ended				Pro Forma				Six Months Ended
		June 30, 2012				Adjustments				June 30, 2012
Revenues:
Product sales, net		$	3,468			$	(3,468	)(c)		$	—
Collaboration revenue			—				—				—
Total revenues			3,468				(3,468	)			—
Costs and expenses:
Cost of product sales			519				(519	)(c)			—
Research and development expenses			19,072				—				19,072
General and administrative expenses			5,399				(410	)(c)			4,989
Total costs and expenses			24,990				(929	)			24,061
Loss from operations			(21,522	)			(2,539	)			(24,061	)
Other income, net			61				—				61
Net loss		$	(21,461	)		$	(2,539	)		$	(24,000	)
Net loss per share:
Basic and diluted		$	(0.34	)						$	(0.38	)
Weighted average shares used in computing net loss per share:
Basic and diluted			62,801,835								62,801,835

See accompanying notes to the unaudited pro forma financial statements.

F-3

GTx, Inc.

UNAUDITED PRO FORMA CONDENSED STATEMENT OF OPERATIONS

FOR THE SIX MONTHS ENDED JUNE 30, 2011

(in thousands, except share and per share data)

		As Reported								Pro Forma
		Six Months Ended				Pro Forma				Six Months Ended
		June 30, 2011				Adjustments				June 30, 2011
Revenues:
Product sales, net		$	2,874			$	(2,874	)(c)		$	—
Collaboration revenue			8,066				—				8,066
Total revenues			10,940				(2,874	)			8,066
Costs and expenses:
Cost of product sales			469				(469	)(c)			—
Research and development expenses			14,894				—				14,894
General and administrative expenses			9,154				(2,976	)(c)			6,178
Total costs and expenses			24,517				(3,445	)			21,072
Loss from operations			(13,577	)			571				(13,006	)
Other income, net			309				—				309
Net loss		$	(13,268	)		$	571			$	(12,697	)
Net loss per share:
Basic and diluted		$	(0.26	)						$	(0.24	)
Weighted average shares used in computing net loss per share:
Basic and diluted			51,844,616								51,844,616

See accompanying notes to the unaudited pro forma financial statements.

F-4

GTx, Inc.

UNAUDITED PRO FORMA STATEMENT OF OPERATIONS

FOR THE YEAR ENDED DECEMBER 31, 2011

(in thousands, except share and per share data)

		As Reported								Pro Forma
		Year Ended				Pro Forma				Year Ended
		December 31, 2011				Adjustments				December 31, 2011
Revenues:
Product sales, net		$	6,673			$	(6,673	)(c)		$	—
Collaboration revenue			8,066				—				8,066
Total revenues			14,739				(6,673	)			8,066
Costs and expenses:
Cost of product sales			1,055				(1,055	)(c)			—
Research and development expenses			31,938				—				31,938
General and administrative expenses			15,438				(3,411	)(c)			12,027
Total costs and expenses			48,431				(4,466	)			43,965
(Loss) income from operations			(33,692	)			(2,207	)			(35,899	)
Other income, net			398				—				398
Net (loss) income		$	(33,294	)		$	(2,207	)		$	(35,501	)
Net (loss) income per share:
Basic and diluted		$	(0.58	)						$	(0.62	)
Weighted average shares used in computing net (loss) income per share:
Basic and diluted			57,359,466								57,359,466

See accompanying notes to the unaudited pro forma financial statements.

F-5

GTx, Inc.

UNAUDITED PRO FORMA STATEMENT OF OPERATIONS

FOR THE YEAR ENDED DECEMBER 31, 2010

(in thousands, except share and per share data)

		As Reported								Pro Forma
		Year Ended				Pro Forma				Year Ended
		December 31, 2010				Adjustments				December 31, 2010
Revenues:
Product sales, net		$	3,827			$	(3,827	)(c)		$	—
Collaboration revenue			56,786				—				56,786
Total revenues			60,613				(3,827	)			56,786
Costs and expenses:
Cost of product sales			768				(768	)(c)			—
Research and development expenses			28,495				—				28,495
General and administrative expenses			17,419				(4,225	)(c)			13,194
Total costs and expenses			46,682				(4,993	)			41,689
(Loss) income from operations			13,931				1,166				15,097
Other income, net			1,363				—				1,363
Net (loss) income		$	15,294			$	1,166			$	16,460
Net (loss) income per share:
Basic and diluted		$	0.39							$	0.42
Weighted average shares used in computing net (loss) income per share:
Basic and diluted			38,874,721								38,874,721

See accompanying notes to the unaudited pro forma financial statements.

F-6

GTx, Inc.

UNAUDITED PRO FORMA STATEMENT OF OPERATIONS

FOR THE YEAR ENDED DECEMBER 31, 2009

(in thousands, except share and per share data)

		As Reported								Pro Forma
		Year Ended				Pro Forma				Year Ended
		December 31, 2009				Adjustments				December 31, 2009
Revenues:
Product sales, net		$	3,289			$	(3,289	)(c)		$	—
Collaboration revenue			11,441				—				11,441
Total revenues			14,730				(3,289	)			11,441
Costs and expenses:
Cost of product sales			1,290				(1,290	)(c)			—
Research and development expenses			32,344				—				32,344
General and administrative expenses			27,778				(613	)(c)			27,165
Total costs and expenses			61,412				(1,903	)			59,509
(Loss) income from operations			(46,682	)			(1,386	)			(48,068	)
Other income, net			188				—				188
(Loss) income before income taxes			(46,494	)			(1,386	)			(47,880	)
Income tax benefit			238				—				238
Net (loss) income		$	(46,256	)		$	(1,386	)		$	(47,642	)
Net (loss) income per share:
Basic and diluted		$	(1.27	)						$	(1.31	)
Weighted average shares used in computing net (loss) income per share:
Basic and diluted			36,415,379								36,415,379

See accompanying notes to the unaudited pro forma financial statements.

F-7

GTx, Inc.

NOTES TO THE UNAUDITED PRO FORMA FINANCIAL STATEMENTS

Pro Forma Adjustments

Pro forma adjustments are necessary to reflect the impact on the Company’s balance sheet as if the Disposition had occurred on June 30, 2012 and to reflect the impact on the Company’s statements of operations as if Disposition had occurred on January 1, 2009. The pro forma adjustments included in the unaudited pro forma financial statements are as follows:

(a) To reflect the cash proceeds from the sale of the FARESTON^® Assets, including purchased product inventory.

(b) To reflect the impact of the Disposition on specified balance sheet items as if the Disposition had occurred on June 30, 2012. This includes the sale of product inventory and recognition of liabilities that are expected to be paid within 30 days of the Disposition.

(c) To reflect the impact of the Disposition on the Company’s operating results as if the Disposition had occurred on January 1, 2009.

F-8