EXHIBIT 99.1
JOINT FILING AGREEMENT
The undersigned, the Reporting Persons named in this Schedule 13G, hereby
agree that this Schedule 13G is filed on a combined basis on behalf of each of
them and that each Reporting Person is individually responsible for the timely
filing of any amendments to this Schedule 13G. Each Reporting Person further
agrees that it is responsible for the completeness and accuracy of the
information concerning such Reporting Persons, respectively, contained in this
Schedule 13G and that it is not responsible for the completeness or accuracy of
the information concerning the other Reporting Persons.
IN WITNESS WHEREOF, the undersigned have executed this Joint Filing
Agreement as of the 14th day of February, 2006.
BIOGEN IDEC INC.
By: /s/ Xxxxxxx X. Xxxxxx
--------------------------------
Name: Xxxxxxx X. Xxxxxx
Title: Vice President, Treasurer
BIOGEN IDEC MA INC.
By: /s/ Xxxxxxx X. Xxxxxx
--------------------------------
Name: Xxxxxxx X. Xxxxxx
Title: Vice President, Treasurer
Page 8 of 8
