EXHIBIT 10.19
AMENDMENT No. 6
to
THE DEVELOPMENT AND MANUFACTURING
SERVICES AGREEMENT
Dated 08 January 2004
Between
LONZA BIOLOGICS PLC
and
TRUBION PHARMACEUTICALS, INC.
CONFIDENTIAL TREATMENT
THIS AMENDMENT No. 6 ("Sixth Amendment") is made the 28th day of April 2005
BETWEEN
LONZA BIOLOGICS PLC of 000 Xxxx Xxxx, Xxxxxx, Xxxxxxxxx XX0 0XX, Xxxxxxx
(hereinafter referred to as "LB"), and
TRUBION PHARMACEUTICALS, INC., of 0000 0xx Xxxxxx, Xxxxx 0000, Xxxxxxx, XX
00000, XXX (herein after referred to as the "Customer")
WHEREAS
A. LB and the Customer entered into a development and manufacturing services
agreement ("the Agreement") dated 08 January 2004, pursuant to which LB
agreed to provide Services to the Customer, and,
B. The Customer now wishes LB to perform additional services under the
Agreement, and,
C. LB is willing to perform such additional services on the terms set out in
the Agreement, and
D. The parties wish to amend the Agreement in accordance with Clause 13.5
thereto.
NOW THEREFORE IT IS HEREBY AGREED as follows:
1. TWO NEW XXXXXX, XXXXXX 00 XXX 00, XXXXX XX ADDED TO SCHEDULE 2 OF THE
AGREEMENT TO READ AS FOLLOWS:
"STAGE 25 ***
BACKGROUND
***
25.1 OBJECTIVES
***.
25.2 ACTIVITIES
***
25.3 DELIVERABLES
25.3.1 A copy of the report of activities as prepared in activity
25.2.11.
25.4 TIMESCALE
Stage 25 can commence upon signature of this Amendment and it is estimated
that Stage 25 will be complete approximately *** from commencement.
CONFIDENTIAL TREATMENT
STAGE 26 ***
BACKGROUND
***
26.1 OBJECTIVES
***
26.2 ACTIVITIES
***
26.3 DELIVERABLES
26.3.1 A copy of the sampling plan prepared in activity 26.2.1.
26.3.2 *** obtained in activity 26.2.12.
26.3.3 Samples from the development study as agreed in activity 26.2.1
and 26.2.14.
26.3.4 A copy of the report of activities as prepared in activity
26.2.15.
26.4 TIMESCALE
Stage 26 can commence upon signature of this Amendment and it is estimated
that Stage 26 will be complete approximately *** from commencement."
SCHEDULE 3 TO THE AGREEMENT SHALL BE AMENDED TO INCLUDE PROVISION FOR
PAYMENT FOR THE ABOVE MENTIONED ADDITIONAL SERVICES, AS SET OUT BELOW HERETO.
INVOICES FOR THESE ADDITIONAL SERVICES SHALL BE ISSUED, AND CUSTOMER PAYMENTS
SHALL BE MADE, IN ***:
"1. PRICE
***
2. PAYMENT
FOR STAGE 25
*** upon commencement of Stage 25.
*** upon completion of Stage 25.
FOR STAGE 26
*** upon commencement of Stage 26.
CONFIDENTIAL TREATMENT
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*** upon completion of Stage 26."
SAVE AS HEREIN PROVIDED ALL OTHER TERMS AND CONDITIONS OF THE AGREEMENT
SHALL REMAIN IN FULL FORCE AND EFFECT.
AS WITNESS the hands of the duly authorised representatives of the parties
hereto the day and year first above written.
Signed for and on behalf of
LONZA BIOLOGICS PLC /s/ Xxxx Imwinkleried
----------------------------------------
Director
Title
Signed for and on behalf of
TUBION PHARMACEUTICALS, INC. /s/ Xxxxxxx X. Xxxxxx
----------------------------------------
Senior VP Research & Development
TITLE
CONFIDENTIAL TREATMENT
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