August 2, 2006 Meda AB Box 906 Pipers vag 2A Solna, Sweden Attention: Anders Lonners, CEO Dear Anders:

Exhibit 10.17

August 2, 2006

Meda AB

Box 906

Pipers vag 2A

17009

Solna, Sweden

Attention: Xxxxxx Xxxxxxx, CEO

Dear Xxxxxx:

This letter will confirm our agreement with Meda that neither BDSI, Arius nor Arius Two will take any action to terminate, by mutual agreement with a third party, any agreement which would cause a termination of Meda’s rights under the License and Development Agreement and each document, instrument, agreement, license and/or sublicense related thereto, unless provision is made for Meda’s rights under the License and Development Agreement to continue undisturbed.

Very Truly Yours,
BioDelivery Sciences International, Inc.
By:		/s/ Xxxx X. Xxxxx
Arius Pharmaceuticals, Inc.
By:		/s/ Xxxx X. Xxxxx
Arius Two, Inc.
By:		/s/ Xxxx X. Xxxxx