Exhibit 10.16.1 AMENDMENT TO CONSULTING AGREEMENT THIS AMENDMENT TO THE CONSULTING AGREEMENT EFFECTIVE April 16, 1996 ("the Amendment") is made and entered into this 1st day of August, 2000 by and between SeraCare, Inc., a Delaware Corporation...

                                                              Exhibit 10.16.1


                      AMENDMENT TO CONSULTING AGREEMENT

     THIS AMENDMENT TO THE CONSULTING AGREEMENT EFFECTIVE April 16, 1996
("the Amendment") is made and entered into this 1st day of August, 2000 by
and between SeraCare, Inc., a Delaware Corporation (referred herein as the
"Corporation") and Xxx Xxxxxxxx (the "Contractor").

WHEREAS, the Corporation previously entered into a consulting agreement
effective on April 16, 1996 (the "Consulting Agreement");

AND WHEREAS, on January 29, 1998 the Corporation previously extended the
Consulting Agreement for three years through April 15, 2002;

AND WHEREAS, the Corporation hereby wishes to amend the Consulting Agreement
again as specified herein;

AND WHEREAS, the Contractor wishes to have the Consulting Agreement amended as
specified herein;

Now Therefore, the following amendment to the Consulting Agreement is hereby
agreed to by the Corporation:

     1.   The consulting fee payable to Mr. Xxx Xxxxxxxx is hereby increased
          to $70,000. This increase is in lieu of any cash directors fees to
          which Xx. Xxxxxxxx is or may become entitled to as a director of
          SeraCare, Inc.


All other terms, conditions and provisions of the Consulting Agreement shall
remain effective throughout the extended term of this Amendment.


SERACARE, INC.

/s/ Xxxxx X. Xxxxxxx
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Xxxxx X. Xxxxxxx
Executive Vice President & CFO