FIFTH LEASE AMENDMENT

FIFTH LEASE AMENDMENT

THIS FIFTH LEASE AMENDMENT (this “Amendment”) is made this 19 day of August, 2010, between LIBERTY PROPERTY LIMITED PARTNERSHIP, a Pennsylvania limited partnership (“Landlord”) and CUTANEA LIFE SCIENCES, INC., a Delaware corporation (“Tenant”).

BACKGROUND

A.           Landlord and Tenant are parties to a Lease Agreement dated January 20, 2006, as amended by a First Amendment to Lease Agreement dated as of February 27, 2009, a Second Amendment to Lease Agreement dated as of August 1, 2009, a Third Amendment to Lease Agreement dated as of December 21, 2009, and a Fourth Amendment to Lease Agreement dated as of March 12, 2010 (collectively, the “Lease”) pursuant to which Tenant occupies Suite 355 consisting of approximately 3,330 rentable square feet (“Premises”) in the building commonly known as 0 Xxxxx Xxxxxx Xxxxxxx, Xxxxxxx, Xxxxxxxxxxxx (the “Building”). Tenant formerly occupied Suite 200 in the Building.

B.           The Expiration Date of the Lease prior to this Amendment is July 31,2010.

C.           Tenant wishes to extend the term of the Lease.

Accordingly, the parties agree as follows:

1.           Term. The term of the Lease is extended through December 31, 2010.

2.           Minimum Annual Rent. Section 1(f) of the Lease is amended by adding the following:

LEASE PERIOD		MONTHLY RENT
08/01/10-12/31/10		$3,424.35

3.           Annual Operating Expenses. Tenant shall continue to pay Annual Operating Expenses and monthly installments on account of estimated Annual Operating Expenses based on Tenant’s Share, which shall be subject to reconciliation and adjustment as provided in Section 6 of the Lease (currently estimated to be $2,591.85 per month).

4.           As-Is. Tenant accepts the Premises in its “As-Is” condition, and Landlord shall not be required to further improve the Premises. Tenant shall not make other improvements to the Premises, except painting and carpeting at Tenant’s option, and those repairs required by the Lease.

5.           Broker. Tenant represents and warrants to Landlord that it has dealt with no brokers in connection with this Amendment other than Xxxxxxx & Xxxxxxxxx of Pennsylvania. Tenant shall indemnify and hold Landlord harmless from a breach of this representation and warranty.

6.           Capitalized Terms. All capitalized terms used and not separately defined in this Amendment have the meanings assigned to them in the Lease.

7.           Counterparts. This Amendment may be executed in counterparts and may be delivered by electronic transmittal of signed original counterparts, which shall have the same full force and effect as if an original executed copy of this Amendment had been delivered.

8.           Full Force and Effect. Except as expressly modified herein, the terms and conditions of the Lease remain unchanged and in full force and effect.

9.           Default. To Tenant’s knowledge, there are no uncured defaults on the part of Landlord under the Lease, and there are no events which have occurred that, with the giving of notice or the passage of time or both, would result in a default by Landlord under the Lease. At the present time Tenant has no claim against Landlord under the Lease.

10.         Confession of Judgment.

(a)           If an Event of Default occurs relating to Tenant’s non-payment of the Rent due under the Lease, Tenant hereby authorizes any attorney of any court of record of the Commonwealth of Pennsylvania to appear for Tenant and to confess judgment against Tenant, and in favor of Landlord, for all Rent due plus costs and an attorney’s collection commission equal to the greater of 10% of all Rent or $1,000, for which the Lease or a true and correct copy of the Lease shall be good and sufficient warrant. TENANT UNDERSTANDS THAT THE FOREGOING PERMITS LANDLORD TO ENTER A JUDGMENT AGAINST TENANT WITHOUT PRIOR NOTICE OR HEARING. ONCE SUCH A JUDGMENT HAS BEEN ENTERED AGAINST TENANT, ONE OR MORE WRITS OF EXECUTION OR WRITS OF GARNISHMENT MAY BE ISSUED THEREON WITHOUT FURTHER NOTICE TO TENANT AND WITHOUT A HEARING, AND, PURSUANT TO SUCH WRITS, LANDLORD MAY CAUSE THE SHERIFF OF THE COUNTY IN WHICH ANY PROPERTY OF TENANT IS LOCATED TO SEIZE TENANT’S PROPERTY BY LEVY OR ATTACHMENT. IF THE JUDGMENT AGAINST TENANT REMAINS UNPAID AFTER SUCH LEVY OR ATTACHMENT, LANDLORD CAN CAUSE SUCH PROPERTY TO BE SOLD BY THE SHERIFF EXECUTING THE WRITS, OR, IF SUCH PROPERTY CONSISTS OF A DEBT OWED TO TENANT BY ANOTHER ENTITY, LANDLORD CAN CAUSE SUCH DEBT TO BE PAID DIRECTLY TO LANDLORD IN AN AMOUNT UP TO BUT NOT TO EXCEED THE AMOUNT OF THE JUDGMENT OBTAINED BY LANDLORD AGAINST TENANT, PLUS THE COSTS OF THE EXECUTION. Such authority shall not be exhausted by one exercise thereof, but judgment may be confessed as aforesaid from time to time as often as any of the Rent and other sums shall fall due or be in arrears, and such powers may be exercised as well after the expiration of the Second Extension Term and during any extended or renewal term and after the expiration of any extended or renewal term of the Lease.

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(b)           When the Lease and the Term or any extension thereof have been terminated on account of any default by Tenant, or when the Term or any extension thereof has expired, Tenant hereby authorizes any attorney of any court of record of the Commonwealth of Pennsylvania to appear for Tenant and for anyone claiming by, through or under Tenant and to confess judgment against all such parties, and in favor of Landlord, in ejectment and for the recovery of possession of the Premises, for which the Lease or a true and correct copy of thereof shall be good and sufficient warrant. AFTER THE ENTRY OF ANY SUCH JUDGMENT A WRIT OF POSSESSION MAY BE ISSUED THEREON WITHOUT FURTHER NOTICE TO TENANT AND WITHOUT A HEARING. If for any reason after such action shall have been commenced it shall be determined and possession of the Premises remain in or be restored to Tenant, Landlord shall have the right for the same default and upon any subsequent default(s) or upon the termination of the Lease or Tenant’s right of possession as herein set forth, to again confess judgment as herein provided, for which the Lease or a true and correct copy thereof shall be good and sufficient warrant.

(c)           The warrants to confess judgment set forth above shall continue in full force and effect and be unaffected by amendments to the Lease or other agreements between Landlord and Tenant even if any such amendments or other agreements increase Tenant’s obligations or expand the size of the Premises.

(d)           TENANT EXPRESSLY AND ABSOLUTELY KNOWINGLY AND EXPRESSLY WAIVES AND RELEASES (i) ANY RIGHT, INCLUDING, WITHOUT LIMITATION, UNDER ANY APPLICABLE STATUTE, WHICH TENANT MAY HAVE TO RECEIVE A NOTICE TO QUIT PRIOR TO LANDLORD COMMENCING AN ACTION FOR REPOSSESSION OF THE PREMISES AND (ii) ANY RIGHT WHICH TENANT MAY HAVE TO NOTICE AND TO HEARING PRIOR TO A LEVY UPON OR ATTACHMENT OF TENANT’S PROPERTY OR THEREAFTER AND (iii) ANY PROCEDURAL ERRORS IN CONNECTION WITH THE ENTRY OF ANY SUCH JUDGMENT OR IN THE ISSUANCE OF ANY ONE OR MORE WRITS OF POSSESSION OR EXECUTION OR GARNISHMENT THEREON.

To evidence the parties’ agreement with this Amendment, Landlord and Tenant have executed it on the day and year first above written.

	LANDLORD:
	LIBERTY PROPERTY LIMITED PARTNERSHIP
	By:	Liberty Property Trust, Sole General Partner
	By:	/s/ Xxxxx X. Xxxxxxxxxx, Xx.
		Xxxxx X. Xxxxxxxxxx, Xx.
		Sr. Vice President / Regional Director
	TENANT:
	CUTANEA LIFE SCIENCES, INC.
	By:	/s/ Xxxxxx X. Xxxxxxxxx
	Name:	XXXXXX X. XXXXXXXXX
	Title:	PRES & CEO

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