1st Amendment of the Distribution Agreement, of April 1, 2005

Exhibit 10.12A

1^st Amendment of the
Distribution Agreement, of April 1, 2005

between Fluidigm Corporation, a corporation of the State of California, having an office at 0000 Xxxxxxxxx Xxxxx, Xxxxx Xxx Xxxxxxxxx XX 00000, Xxxxxx Xxxxxx of America (“FC”), and Eppendorf AG, a German corporation, having its headquarter at Xxxxxxxxxxxxx 0, X-00000 Xxxxxxx, Xxxxxxx (“EAG”), each hereinafter referred to as the “Party” or collectively called the “Parties”.

WHEREAS, FC desires to calibrate and adjust the special brand version of the EAG Mastercycler personal distributed by FC for the exclusive handling of FC microfluidic chips.

NOW, THEREFORE, in consideration of the premises and the mutual agreements and covenants contained in this Amendment, the Parties hereto hereby agree to amend § 11 and § 18 as follows:

§ 11 will be supplemented by a new paragraph:

The Warranty as specified above will not be affected, with the exception of subsequent damages of the Cycler as a result of incorrect execution of the calibration and/or adjustment.

§ 18 will be supplemented by the following new paragraphs:

EAG has agreed to send the protocol for calibration / adjustment under the assumption, that the first 2 — 3 cyclers from the stock of FC will be used for testing.

With the start of the testing, the serial numbers of the cyclers adjusted or calibrated by FC will be documented and sent to Eppendorf for notification.

Any additional cyclers treated in this way will also be documented by FC and FC will inform EAG about this by sending the serial numbers for those cyclers.

All other terms and conditions of the Distribution Agreement shall remain in full force and effect and no fee will be charged for the services described above.

This Amendment is effective as of December 1, 2007.

IN WITNESS WHEREOF, the Parties have caused this Amendment to be executed by their duly authorized representatives.

South San Francisco, the                     

Fluidigm Corporation
President / CEO
 

/s/ Xxxxx X. Xxxxxxxxxxx  

Xxxxx X. Xxxxxxxxxxx 

Hamburg, the July 10, 2008

Eppendorf AG
/s/ Heinz Xxxxxxx Xxxxx, Ph. D.		/s/ Xxxxxxx Xxxxxxxxx, Ph. X.
Xxxxx Xxxxxxx Xxxxx, Ph. D.		Xxxxxxx Xxxxxxxxx, Ph. D.
Board Member, Technology		Board Member, Marketing and Sales