ASSISTANCE AGREEMENT AMYRIS BIOTECHNOLOGY, INC. Attn: KINKEAD REILING 5885 HOLLIS STREET SUITE 100 EMERYVILLE CA 946082059 Govt. Share Cost Share Total : $ 24,341,409.00 : $ 10,591,590.00 : $ 34,932,999.00 This action Total : $0.00 : $24,341,409.00

Exhibit 10.13

NOT SPECIFIED /OTHER

ASSISTANCE AGREEMENT

1. Award No. DE-EE0002869

2. Modification No. 002

3. Effective Date 12/28/2009

4. CFDA No. 81.087

5. Awarded To AMYRIS BIOTECHNOLOGIES, INC. Attn: XXXXXXX XXXXXXX 0000 XXXXXX XXXXXX XXXXX 000 XXXXXXXXXX XX 000000000

6. Sponsoring Office Golden Field Office U.S. Department of Energy Golden Field Office 0000 Xxxx Xxxx. Xxxxxx XX 00000

7. Period of Performance 12/28/2009 through 06/30/2012

8. Type of Agreement ¨ Grant x  Cooperative Agreement ¨ Other

9. Authority 109-58 Energy Policy Act (2005) 111-5 Recovery Xxx 0000

10. Purchase Request or Funding Document No. 10EE003980

11. Remittance Address

12. Total Amount

13. Funds Obligated

AMYRIS BIOTECHNOLOGY, INC. Attn: XXXXXXX XXXXXXX 0000 XXXXXX XXXXXX XXXXX 000 XXXXXXXXXX XX 946082059

Govt. Share Cost Share Total

:  $ 24,341,409.00 :  $ 10,591,590.00 :  $ 34,932,999.00

This action Total

:    $0.00 :    $24,341,409.00

14. Principal Investigator Xxxx Xxxxxxxxx Phone: 000-000-0000

15. Program Manager Xxxxx Xxxx Xxxxxxxx Phone: 000-000-0000

16. Administrator Golden Field Office U.S. Department of Energy Golden Field Office 0000 Xxxx Xxxx. Xxxxxx XX 00000-0000

17. Submit Payment Requests To OR for Golden U.S. Department of Energy Oak Ridge Financial Service Center X.X. Xxx 0000 Xxx Xxxxx XX 00000

18. Paying Office OR for Golden U.S. Department of Energy Oak Ridge Financial Service Center X.X. Xxx 0000 Xxx Xxxxx XX 00000

19. Submit Reports To

20. Accounting and Appropriation Data See Schedule

21. Research Title and/or Description of Project RECOVERY ACT: SCALE-UP & MOBILIZATION OF RENEWABLE DIESEL & CHEMICAL PRODUCTION FROM COMMON INTERMEDIATE USING US-BASED FERMENTABLE SUGAR FEEDSTOCKS

For the Recipient

For the United States of America

22. Signature of Person Authorized to Sign

25. Signature of Grants/Agreements Officer Signature on File

23. Name and Title

24. Date Signed

26. Name of Officer Xxxxx Xxxxx

27. Date Signed 04/19/2010

NOT SPECIFIED /OTHER

NOT SPECIFIED /OTHER

  CONTINUATION SHEET REFERENCE NO. OF DOCUMENT BEING CONTINUED   DE-EE0002869/002   PAGE OF       2    |     2

NAME OF OFFEROR OR CONTRACTOR

AMYRIS BIOTECHNOLGOIES, INC.

ITEM NO. (A)

SUPPLIES/SERVICES (B)

QUANTITY (C)

UNIT (D)

UNIT PRICE (E)

AMOUNT (F)

DUNS Number: 185930182 The purpose of this modification is to make the project and budget periods co-extensive, ending on 6/30/2012. All other terms and conditions remain unchanged. In Block 7 of the Assistance Agreement, the Period of Performance reflects the beginning of the Project Period through the end of the current Budget Period, shown as 12/28/2009 through 6/30/2012. DOE Award Administrator: Xxxxxx Xxxx E-mail: xxxxxx.xxxx@xx.xxx.xxx Phone: 000-000-0000 DOE Project Officer: Xxxxx Xxxxxxxx E-mail: xxxxx.xxxxxxxx@xx.xxx.xxx Phone: 000-000-0000 Recipient Business Officer: Xxxx Xxxx E-mail: xxxx@xxxxxx.xxx Phone: 000-000-0000 Recipient Principal Investigator: Xxxx Xxxxxxxxx E-mail: xxxxxxxxx@xxxxxx.xxx Phone: 000-000-0000 “Electronic signature or signatures as used in this document means a method of signing an electronic message that— (A) Identifies and authenticates a particular person as the source of the electronic message; (B) Indicates such person's approval of the information contained in the electronic message; and, (C) Submission via FedConnect constitutes electronically signed documents.” ASAP: NO Extent Competed: COMPETED Xxxxx-Xxxxx Act: YES

JULY 2004

NOT SPECIFIED /OTHER