Exhibit 1.1
3,112,945 SHARES
ARIAD PHARMACEUTICALS, INC.
COMMON STOCK
UNDERWRITING AGREEMENT
October 19, 2006
CREDIT SUISSE SECURITIES (USA) LLC
Eleven Madison Avenue,
New York, N.Y. 10010-3629
Ladies and Gentlemen:
1. Introductory. ARIAD Pharmaceuticals, Inc., a Delaware corporation
("COMPANY"), agrees with you ("UNDERWRITER") to issue and sell to the
Underwriter 3,112,945 shares ("FIRM SECURITIES") of its common stock, $0.001 par
value per share ("COMMON STOCK"), and also proposes to issue and sell to the
Underwriter, at the option of the Underwriter, an aggregate of not more than
466,942 additional shares ("OPTIONAL SECURITIES") of its Securities as set forth
below. The Firm Securities and the Optional Securities are herein collectively
called the "OFFERED SECURITIES".
2. Representations and Warranties of the Company. The Company
represents and warrants to, and agrees with, the Underwriter that:
(a) Filing and Effectiveness of Registration Statements;
Certain Defined Terms. The Company has filed with the Commission a
registration statement on Form S-3 (No. 333-122909), including a
related prospectus or prospectuses, and a registration statement on
Form S-3 (No. 333-111401), including a related prospectus or
prospectuses and registration statements on Form S-3 filed pursuant to
Rule 462(b) of the Rules and Regulations, which together cover the
registration of the Offered Securities under the Act. Each such
registration statement has become effective. "REGISTRATION STATEMENTS"
at any particular time means such registration statements in the form
then filed with the Commission, including any amendment thereto, any
document incorporated by reference therein and all 430B Information and
all 430C Information with respect to such registration statements, that
in any case has not been superseded or modified. "REGISTRATION
STATEMENTS" without reference to a time means the Registration
Statements as of the Effective Date. For purposes of this definition,
430B Information shall be considered to be included in the Registration
Statements as of the time specified in Rule 430B.
For purposes of this Agreement:
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"430B INFORMATION" means information included in any prospectus then
deemed to be a part of the Registration Statements pursuant to Rule
430B(e) or retroactively deemed to be a part of the Registration
Statements pursuant to Rule 430B(f).
"430C INFORMATION" means information included in any prospectus then
deemed to be a part of the Registration Statements pursuant to Rule
430C.
"ACT" means the Securities Act of 1933, as amended.
"APPLICABLE TIME" means 4:00 p.m. (Eastern time) on October 19, 2006.
"CLOSING DATE" has the meaning defined in Section 3 hereof.
"COMMISSION" means the Securities and Exchange Commission.
"EFFECTIVE DATE" of the Registration Statements relating to the Offered
Securities means the time of the first contract of sale for the Offered
Securities.
"EXCHANGE ACT" means the Securities Exchange Act of 1934.
"FINAL PROSPECTUSES" means the Statutory Prospectuses that disclose the
public offering price, other 430B Information and other final terms of
the Offered Securities and otherwise satisfies Section 10(a) of the
Act.
"GENERAL USE ISSUER FREE WRITING PROSPECTUS" means any Issuer Free
Writing Prospectus that is intended for general distribution to
prospective investors, as evidenced by its being so specified in
Schedule A to this Agreement.
"ISSUER FREE WRITING PROSPECTUS" means any "issuer free writing
prospectus," as defined in Rule 433, relating to the Offered Securities
in the form filed or required to be filed with the Commission or, if
not required to be filed, in the form retained in the Company's records
pursuant to Rule 433(g).
"LIMITED USE ISSUER FREE WRITING PROSPECTUS" means any Issuer Free
Writing Prospectus that is not a General Use Issuer Free Writing
Prospectus.
"RULES AND REGULATIONS" means the rules and regulations of the
Commission.
"SECURITIES LAWS" means, collectively, the Xxxxxxxx-Xxxxx Act of 2002
("XXXXXXXX-XXXXX"), the Act, the Exchange Act, the Rules and
Regulations, the auditing principles, rules, standards and practices
applicable to auditors of "issuers" (as defined in Xxxxxxxx-Xxxxx)
promulgated or approved by the Public Company Accounting Oversight
Board and, as applicable, the rules of the New York Stock Exchange and
The NASDAQ Stock Market ("EXCHANGE RULES").
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"STATUTORY PROSPECTUSES" with reference to any particular time means
the prospectus relating to the Offered Securities that is included in
the Registration Statements immediately prior to that time, including
all 430B Information and all 430C Information with respect to the
Registration Statements. For purposes of the foregoing definition, 430B
Information shall be considered to be included in the Statutory
Prospectuses only as of the actual time that form of prospectus
(including a prospectus supplement) is filed with the Commission
pursuant to Rule 424(b) and not retroactively.
Unless otherwise specified, a reference to a "rule" is to the indicated
rule under the Act.
(b) Compliance with Securities Act Requirements. (i) (A) At
the time the Registration Statements initially became effective, (B) at
the time of each amendment thereto for the purposes of complying with
Section 10(a)(3) of the Act (whether by post-effective amendment,
incorporated report or form of prospectus), (C) on the Effective Date
relating to the Offered Securities and (D) on the Closing Date, the
Registration Statements conformed and will conform in all material
respects with the requirements of the Act and the Rules and Regulations
and did not and will not include any untrue statement of a material
fact or omit to state any material fact required to be stated therein
or necessary to make the statements therein, in light of the
circumstances under which they were made, not misleading and (ii) (A)
on its date, (B) at the time of filing the Final Prospectuses pursuant
to Rule 424(b) and (C) on the Closing Date, the Final Prospectuses will
conform in all material respects to the requirements of the Act and the
Rules and Regulations, and will not include any untrue statement of a
material fact or omit to state any material fact required to be stated
therein or necessary in order to make the statements therein, in light
of the circumstances under which they were made, not misleading. The
preceding sentence does not apply to statements in or omissions from
any such document based upon written information furnished to the
Company by the Underwriter, if any, specifically for use therein, it
being understood and agreed that the only such information is that
described as such in Section 8(b) hereof.
(c) Shelf Registration Statements. The date of this Agreement
is not more than three years subsequent to the more recent of the
initial effective dates of the Registration Statements or December 1,
2005. If, immediately prior to the third anniversary of the more recent
of the initial effective dates of the Registration Statements or
December 1, 2005, any of the Offered Securities remain unsold by the
Underwriter, the Company will prior to that third anniversary file, if
it has not already done so, a new shelf registration statement relating
to the Offered Securities, in a form reasonably satisfactory to the
Underwriter, and will use reasonable best efforts to cause such
registration statement to be declared effective within 180 days after
that third anniversary, and will take all other action necessary or
appropriate to permit the public offering and sale of the Offered
Securities to continue as contemplated in the expired registration
statement relating to the Offered Securities. References herein to the
Registration Statements shall include such new shelf registration
statement.
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(d) Ineligible Issuer Status. (i) At the earliest time after
the filing of the Registration Statements that the Company or another
offering participant made a bona fide offer (within the meaning of Rule
164(h)(2)) of the Offered Securities and (ii) at the date of this
Agreement, the Company was not and is not an "ineligible issuer," as
defined in Rule 405, including (x) the Company or any other subsidiary
in the preceding three years not having been convicted of a felony or
misdemeanor or having been made the subject of a judicial or
administrative decree or order as described in Rule 405 and (y) the
Company in the preceding three years not having been the subject of a
bankruptcy petition or insolvency or similar proceeding, not having had
a registration statement be the subject of a proceeding under Section 8
of the Act and not being the subject of a proceeding under Section 8A
of the Act in connection with the offering of the Securities, all as
described in Rule 405.
(e) General Disclosure Package. As of the Applicable Time,
neither (i) the General Use Issuer Free Writing Prospectus(es) issued
at or prior to the Applicable Time, the preliminary prospectus
supplements, dated October 19, 2006, together with the accompanying
prospectuses (which are the most recent Statutory Prospectuses
distributed to investors generally) and any other documents listed or
disclosures stated in Schedule A to this Agreement to be included in
the General Disclosure Package, all considered together (collectively,
the "GENERAL DISCLOSURE PACKAGE"), nor (ii) any individual Limited Use
Issuer Free Writing Prospectus, when considered together with the
General Disclosure Package, included any untrue statement of a material
fact or omitted to state any material fact necessary in order to make
the statements therein, in the light of the circumstances under which
they were made, not misleading. The preceding sentence does not apply
to statements in or omissions from any Statutory Prospectus or any
Issuer Free Writing Prospectus in reliance upon and in conformity with
written information furnished to the Company by the Underwriter
specifically for use therein, it being understood and agreed that the
only such information furnished by the Underwriter consists of the
information described as such in Section 8(b) hereof.
(f) Issuer Free Writing Prospectuses. Each Issuer Free Writing
Prospectus, as of its issue date and at all subsequent times through
the completion of the public offer and sale of the Offered Securities
or until any earlier date that the Company notified or notifies the
Underwriter as described in the next sentence, did not, does not and
will not include any information that conflicted, conflicts or will
conflict with the information then contained in the Registration
Statements. If at any time following issuance of an Issuer Free Writing
Prospectus there occurred or occurs an event or development as a result
of which such Issuer Free Writing Prospectus conflicted or would
conflict with the information then contained in the Registration
Statements or as a result of which such Issuer Free Writing Prospectus,
if republished immediately following such event or development, would
include an untrue statement of a material fact or omitted or would omit
to state a material fact necessary in order to make the statements
therein, in the light of the circumstances under which they were made,
not misleading, (i) the Company has promptly notified or will promptly
notify the Underwriter and (ii) the Company has promptly amended or
will promptly amend or supplement such Issuer Free Writing Prospectus
to eliminate or
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correct such conflict, untrue statement or omission. The preceding two
sentences do not apply to statements in or omissions from any Statutory
Prospectus or any Issuer Free Writing Prospectus in reliance upon and
in conformity with written information furnished to the Company by the
Underwriter specifically for use therein, it being understood and
agreed that the only such information furnished by the Underwriter
consists of the information described as such in Section 8(b) hereof.
(g) Good Standing of the Company. The Company has been duly
incorporated and is existing and in good standing under the laws of the
State of Delaware, with corporate power and authority to own its
properties and conduct its business as described in the General
Disclosure Package; and the Company is duly qualified to do business as
a foreign corporation in good standing in all other jurisdictions in
which its ownership or lease of property or the conduct of its business
requires such qualification, except to the extent that the failure to
be so qualified or be in good standing would not materially and
adversely affect the Company and its subsidiaries or their businesses,
properties, business prospects, conditions (financial or other) or
results of operations, taken as a whole (such effect is referred to
herein as a "Material Adverse Effect").
(h) Subsidiaries. Each subsidiary of the Company has been duly
organized and is existing and in good standing under the laws of the
jurisdiction of its incorporation, with requisite power and authority
to own its properties and conduct its business as described in the
General Disclosure Package; and each subsidiary of the Company is duly
qualified to do business as a foreign corporation in good standing in
all other jurisdictions in which its ownership or lease of property or
the conduct of its business requires such qualification, except to the
extent that the failure to be so qualified or be in good standing would
not have a Material Adverse Effect; all of the issued and outstanding
capital stock of each subsidiary of the Company has been duly
authorized and validly issued and is fully paid and nonassessable; and
the capital stock of each subsidiary owned by the Company, directly or
through subsidiaries, is owned free from liens, encumbrances and
defects, except as described in the Security Agreement (All Assets)
dated as of March 12, 2003 between the Company and Citizens Bank of
Massachusetts (the "Bank"), the Security Agreement (All Assets) dated
as of March 12, 2003 between AGTI and the Bank and the Security
Agreement (All Assets) dated as of March 12, 2003 between ARIAD
Corporation and the Bank.
(i) Capital Stock. The Offered Securities and all other
outstanding shares of capital stock of the Company have been duly
authorized; all outstanding shares of capital stock of the Company are,
and, when the Offered Securities have been delivered and paid for in
accordance with this Agreement on the Closing Date, such Offered
Securities will have been validly issued, fully paid and nonassessable,
will conform to the information in the General Disclosure Package and
to the description of such Offered Securities contained in the Final
Prospectuses, the stockholders of the Company have no statutory or
contractual preemptive rights with respect to its Common Stock; none of
the outstanding shares of capital stock of the Company are or will have
been issued in violation of any statutory or
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contractual preemptive or similar rights of any security holder; and
the authorized equity capitalization of the Company is as set forth in
the General Disclosure Package.
(j) No Finder's Fee. There are no contracts, agreements or
understandings between the Company and any person that would give rise
to a valid claim against the Company or any Underwriter for a brokerage
commission, finder's fee or other like payment.
(k) Financial Statements. The financial statements and
schedules included or incorporated by reference in the Registration
Statements and the General Disclosure Package present fairly in all
material respects the financial condition of the Company and its
consolidated subsidiaries as of the respective dates thereof and the
results of operations and cash flows of the Company and its
consolidated subsidiaries for the respective periods covered thereby,
all in conformity with generally accepted accounting principles applied
on a consistent basis throughout the entire period involved, except as
otherwise disclosed in the General Disclosure Package. No other
financial statements or schedules of the Company are required by the
Act, the Exchange Act, or the Rules and Regulations to be included in
the Registration Statements or the General Disclosure Package. Deloitte
& Touche LLP ("ACCOUNTANTS"), who have reported on such financial
statements and schedules, are independent accountants with respect to
the Company as required by the Act and the Rules and Regulations and
Rule 3600T of the Public Company Accounting Oversight Board ("PCAOB").
The summaries and selected consolidated financial and statistical data
included in the Registration Statements present fairly the information
shown therein and have been compiled on a basis consistent with the
audited financial statements presented in the Registration Statements.
(l) Absence of Changes. Subsequent to the respective dates as
of which information is given in the Registration Statements and the
General Disclosure Package and prior to or on the Closing Date, except
as set forth in or contemplated by the Registration Statements and the
General Disclosure Package, (i) there has not been and will not have
been any change in the capitalization of the Company (other than in
connection with the grant or exercise of options to purchase the Common
Stock granted pursuant to the Company's stock option plans from the
shares reserved therefore, the conversion of convertible debt
outstanding on the date hereof into shares of Common Stock or the
issuance of shares under the Company's existing employee stock purchase
plan as described in the Registration Statements), or any Material
Adverse Effect arising for any reason whatsoever, (ii) the Company has
not incurred and will not incur, except in the ordinary course of
business as described in the General Disclosure Package, any material
liabilities or obligations, direct or contingent, the Company has not
entered into and will not enter into, except in the ordinary course of
business as described in the General Disclosure Package, any material
transactions other than pursuant to this Agreement and the transactions
referred to herein and (iii) the Company has not and will not have paid
or declared any dividends or other distributions of any kind on any
class of its capital stock.
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(m) Not An Investment Company. The Company is not, will not
become as a result of the transactions contemplated hereby, and will
not conduct its business in a manner that would cause it to become, an
"investment company" or an "affiliated person" of, or "promoter" or
"principal underwriter" for, an "investment company," as such terms are
defined in the Investment Company Act of 1940, as amended.
(n) Litigation. Except as disclosed in the General Disclosure
Package, there are no actions, suits or proceedings pending or, to the
knowledge of the Company, threatened against or affecting the Company
or any of its officers in their capacity as such, before or by any
federal or state court, commission, regulatory body, administrative
agency or other governmental body, domestic or foreign, wherein an
unfavorable ruling, decision or finding would reasonably be expected to
have a Material Adverse Effect.
(o) Absence of Existing Defaults and Conflicts. Neither the
Company nor any subsidiary is (i) in violation of any provision of its
certificate of incorporation or bylaws, (ii) in default in any respect,
and no event has occurred which, with notice or lapse of time or both,
would constitute such a default, in the due performance or observance
of any term, covenant, or condition of any indenture, contract, lease,
mortgage, deed of trust, note agreement, loan agreement or other
agreement, obligation, condition, covenant or instrument to which it is
a party or by which it is bound or to which any of its property or
assets is subject, or (iii) in violation in any respect of any statute,
law, rule, regulation, ordinance, judgment, order or decree of any
court, regulatory body, administrative agency, governmental body,
arbitrator or other authority having jurisdiction over the Company, any
subsidiary or any of their properties, as applicable, except, with
respect to clauses (ii) and (iii), any violations or defaults which,
individually or in the aggregate, would not reasonably be expected to
have a Material Adverse Effect.
(p) Absence of Further Requirements. No consent, approval,
authorization or order of, or any filing or declaration with, any court
or governmental agency or body is required for the consummation by the
Company of the transactions on its part contemplated herein, except
such as have been obtained under the Act or the Rules and Regulations
and such as may be required under state securities or Blue Sky laws or
the bylaws and rules of the National Association of Securities Dealers,
Inc. ("NASD") or the NASDAQ Stock Market in connection with the
offering of the Offered Securities.
(q) Authorization; Absence of Defaults and Conflicts Resulting
from Transaction. The Company has full corporate power and authority to
enter into this Agreement. This Agreement has been duly authorized,
executed and delivered by the Company. The execution, delivery and
performance of this Agreement and the consummation of the transactions
contemplated hereby will not (i) result in the creation or imposition
of any lien, charge or encumbrance upon any of the assets of the
Company or any subsidiary of the Company pursuant to the terms or
provisions of, or result in a breach or violation of any of the terms
or provisions of, or conflict with or constitute a default under, or
give any party a right to terminate any of its obligations under, or
result in the acceleration of
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any obligation under, (A) the certificate of incorporation or bylaws of
the Company or any subsidiary of the Company, or (B) any indenture,
mortgage, deed of trust, voting trust agreement, loan agreement, bond,
debenture, note agreement or other evidence of indebtedness, lease,
contract or other agreement or instrument to which the Company is a
party or by which the Company, any subsidiary of the Company or any of
their properties is bound or affected, except, in the case of clause
(i)(B), any lien, breach, violation, conflict, default or acceleration
that, would not, individually or in the aggregate, reasonably be
expected to have a Material Adverse Effect, or (ii) violate or conflict
with any judgment, ruling, decree, order, statute, rule or regulation
of any court or other governmental agency or body applicable to the
business or properties of the Company or any subsidiary of the Company.
(r) Title to Property. The Company and its subsidiaries have
good and marketable title to all properties and assets described in the
General Disclosure Package as owned by them, free and clear of all
liens, charges, encumbrances or restrictions, except such as are
described in the General Disclosure Package or are not material to the
business of the Company or its subsidiaries. The Company has valid,
subsisting and enforceable leases for the properties described in the
General Disclosure Package as leased by it. The Company and its
subsidiaries own or lease all such properties as are necessary to their
operations as now conducted or as proposed to be conducted, except
where the failure to so own or lease would not reasonably be expected
to have a Material Adverse Effect.
(s) Off Balance Sheet Interests and Contracts. There is no
document, contract, permit or instrument, affiliate transaction or
off-balance sheet transaction (including, without limitation, any
"variable interests" in "variable interest entities," as such terms are
defined in Financial Accounting Standards Board Interpretation No. 46)
of a character required to be described in the Registration Statements
or the General Disclosure Package or to be filed as an exhibit to the
Registration Statements that is not described or filed as required. All
such contracts described in the immediately preceding sentence to which
the Company is a party have been duly authorized, executed and
delivered by the Company, constitute valid and binding agreements of
the Company and are enforceable against and by the Company in
accordance with the terms thereof.
(t) Accuracy of Statements. No statement, representation,
warranty or covenant made by the Company in this Agreement or made in
any certificate or document required by Section 7 of this Agreement to
be delivered to the Underwriter was or will be, when made, inaccurate,
untrue or incorrect in any material respect.
(u) Offering Material; Stabilization. The Company has not
distributed, and will not distribute prior to the Closing Date, any
offering material in connection with the offering and sale of the
Shares other than any preliminary prospectuses, any Permitted Free
Writing Prospectus (as defined in Section 6 below), the Final
Prospectuses, the Registration Statements and other materials, if any,
permitted by the Act. Neither the Company nor any of its directors,
officers or controlling persons has taken, directly or
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indirectly, any action designed, or that might reasonably be expected,
to cause or result, under the Act or otherwise, in, or that has
constituted, stabilization or manipulation of the price of any security
of the Company to facilitate the sale or resale of the Offered
Securities.
(v) Registration Rights. No holder of securities of the
Company has rights to the registration of any securities of the Company
because of the filing of the Registration Statement, which rights have
not been waived by the holder thereof as of the date hereof.
(w) Listing. The Common Stock is registered under Section
12(g) of the Exchange Act and the Offered Securities have been approved
for listing on the NASDAQ Global Market ("NGM"), subject to filing with
The NASDAQ Stock Market of a Notification Form: Listing of Additional
Shares.
(x) Possession of Intellectual Property. Except as disclosed
in or specifically contemplated by the General Disclosure Package, (i)
the Company and its subsidiaries own or have adequate rights to use, or
can acquire on reasonable terms, all trademarks, trade names, domain
names, patents, patent rights, copyrights, technology, know-how
(including trade secrets and other unpatented or unpatentable
proprietary or confidential information, systems or procedures),
service marks, trade dress rights, and other intellectual property
(collectively, "INTELLECTUAL PROPERTY") and have such other licenses,
approvals and governmental authorizations, in each case sufficient to
conduct their business as now conducted and, with respect to our
product candidates, as now proposed to be conducted (as described in
the General Disclosure Package), and to the Company's knowledge, none
of the foregoing Intellectual Property rights owned or licensed by the
Company and its subsidiaries is invalid or unenforceable, (ii) the
Company has no knowledge of any infringement by it or any subsidiary of
Intellectual Property rights of others, where such infringement could
reasonably be expected to have a Material Adverse Effect, (iii) the
Company is not aware of any infringement, misappropriation or violation
by others of, or conflict by others with rights of the Company or any
subsidiary with respect to, any Intellectual Property that could
reasonably be expected to have a Material Adverse Effect, (iv) there is
no claim being made against the Company or any subsidiary or, to the
knowledge of the Company, any employee of the Company or any
subsidiary, regarding Intellectual Property or other infringement that
could reasonably be expected to have a Material Adverse Effect, and (v)
neither the Company nor any subsidiary has received any notice of
infringement with respect to any patent or any notice challenging the
validity, scope or enforceability of any Intellectual Property owned by
or licensed to the Company or any subsidiary, in each case the loss of
which patent or Intellectual Property (or loss of rights thereto) would
have a Material Adverse Effect.
(y) Taxes. The Company has filed all federal, state, local and
foreign income tax returns that have been required to be filed and has
paid all taxes and assessments
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received by it to the extent that such taxes or assessments have become
due. Except as disclosed in the General Disclosure Package, the Company
has no tax deficiency that has been or, to the best knowledge of the
Company, might be asserted or threatened against it that could
reasonably be expected to have a Material Adverse Effect.
(z) Permits and Licenses. The Company and its subsidiaries own
or possess all authorizations, approvals, orders, licenses,
registrations, other certificates and permits of and from all
governmental regulatory officials and bodies, necessary to conduct its
businesses as contemplated in the General Disclosure Package, except
where the failure to own or possess all such authorizations, approvals,
orders, licenses, registrations, other certificates and permits would
not reasonably be expected to have a Material Adverse Effect. There is
no proceeding pending or, to the knowledge of the Company, threatened
(or any basis therefor known to the Company) that may cause any such
authorization, approval, order, license, registration, certificate or
permit to be revoked, withdrawn, cancelled, suspended or not renewed;
and the Company and its subsidiaries are conducting their business in
compliance with all laws, rules and regulations applicable thereto,
except where such noncompliance would not reasonably be expected to
have a Material Adverse Effect.
(aa) FCPA Compliance. The Company has not and, to the
Company's knowledge, none of its employees or agents or the employees
or agents of any subsidiary at any time during the last five years have
(i) made any unlawful contribution to any candidate for foreign office,
or failed to disclose fully any contribution in violation of law, or
(ii) made any payment to any federal or state governmental officer or
official, or other person charged with similar public or quasi-public
duties, other than payments required or permitted by the laws of the
United States or any jurisdiction thereof.
(bb) Internal Controls and Compliance With Xxxxxxxx-Xxxxx Act.
The books, records and accounts of the Company accurately and fairly
reflect in all material respects, in reasonable detail, the
transactions in, and dispositions of, the assets of, and the results of
operations of, the Company. The principal executive officer and
principal financial officer of the Company have made all certifications
required by Sections 302 and 906 of Xxxxxxxx-Xxxxx and the rules and
regulations promulgated in connection therewith with respect to all
reports, schedules, forms, statements and other documents required to
be filed by it with the Commission, and the statements contained in any
such certification are complete and correct. For purposes of the
preceding sentence, "principal executive officer" and "principal
financial officer" shall have the meanings given to such terms in
Xxxxxxxx-Xxxxx. The Company maintains (x) systems of internal
accounting controls sufficient to provide reasonable assurances that
(i) transactions are executed in accordance with management's general
or specific authorizations, (ii) transactions are recorded as necessary
to permit preparation of the Company's consolidated financial
statements in accordance with generally accepted accounting principles
and to maintain asset accountability, (iii) access to assets is
permitted only in accordance with management's general or specific
authorization, and (iv) the recorded accountability for
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assets is compared with the existing assets at reasonable intervals and
appropriate action is taken with respect to any differences, and (y)
disclosure controls and procedures (as defined in Rule 13a-14(c) under
the Exchange Act).
(cc) ERISA Compliance. The Company has fulfilled in all
material respects its obligations, if any, under the minimum funding
standards of Xxxxxxx 000 xx xxx Xxxxxx Xxxxxx Employee Retirement
Income Security Act of 1974 ("ERISA") and the regulations and published
interpretations thereunder with respect to each "plan" (as defined in
Section 3(3) of ERISA and such regulations and published
interpretations) in which employees of the Company is eligible to
participate and each such plan is in compliance in all material
respects with the presently applicable provisions of ERISA and such
regulations and published interpretations. No "prohibited transaction"
(as defined in Section 406 of ERISA, or Section 4975 of the Internal
Revenue Code of 1986, as amended from time to time (the "CODE")) has
occurred with respect to any employee benefit plan which would
reasonably be expected to result in a Material Adverse Effect.
(dd) Labor Issues. No labor problem or dispute with the
employees of the Company or any subsidiary exists or, to the Company's
knowledge, is threatened or imminent, which would reasonably be
expected to result in a Material Adverse Effect. The Company is not
aware that any key employee or significant group of employees of the
Company plans to terminate employment with the Company.
(ee) Statistical and Market-Related Data. Any third-party
statistical and market-related data included or incorporated by
reference in the Registration Statements, the Statutory Prospectuses or
the General Disclosure Package are based on or derived from sources
that the Company believes to be reliable and accurate.
(ff) Forward-Looking Statements. No forward-looking statement
(within the meaning of Section 27A of the Securities Act and Section
21E of the Exchange Act) contained in the Registration Statements and
the General Disclosure Package has been made or reaffirmed without a
reasonable basis or has been disclosed other than in good faith.
(gg) Environmental Laws. The Company and its subsidiaries (i)
are in compliance with any and all applicable federal, state, local and
foreign laws, rules, regulations, decisions and orders relating to the
protection of human health and safety, the environment or hazardous or
toxic substances or wastes, pollutants or contaminants (collectively,
"ENVIRONMENTAL LAWS"); (ii) have received and are in compliance with
all permits, licenses or other approvals required of them under
applicable Environmental Laws to conduct their business; and (iii) have
not received notice of any actual or potential liability for the
investigation or remediation of any disposal or release of hazardous or
toxic substances or wastes, pollutants or contaminants, except in the
case of subsections (i), (ii) and (iii) of this subsection (gg) as
would not, individually or in the aggregate, have a Material Adverse
Effect.
11
(hh) Regulatory Authorizations. The Company and its
subsidiaries possess all certificates, authorizations and permits
issued by the appropriate federal, state or foreign regulatory
authorities necessary to conduct their business as described in the
General Disclosure Package, including without limitation all such
certificates, authorizations and permits required by the United States
Food and Drug Administration (the "FDA") or any other federal, state or
foreign agencies or bodies engaged in the regulation of pharmaceuticals
or biohazardous materials, except where the failure to possess such
certificates, authorizations and permits would not, individually or in
the aggregate, have a Material Adverse Effect; and neither the Company
nor any subsidiary has received any notice of proceedings relating to
the revocation or modification of any such certificate, authorization
or permit which, if the subject of an unfavorable decision, ruling or
finding, would individually or in the aggregate have a Material Adverse
Effect.
(ii) Conduct of Clinical Trials. The studies, tests and
preclinical and clinical trials conducted by or on behalf of the
Company that are described in the General Disclosure Package were and,
if still pending, are being, conducted in compliance in all material
respects with all applicable current Good Laboratory Practices and Good
Clinical Practices. The descriptions of the studies, tests and
preclinical and clinical trials, including the related results and
regulatory status, contained in the General Disclosure Package are
accurate in all material respects. Except as described in the General
Disclosure Package, the Company has not received any written notices,
correspondence or other communication from the FDA or other
governmental agency requiring the termination or suspension of any
clinical trials conducted by, or on behalf of, the Company or in which
the Company has participated.
(jj) Exemption From NASD Filing. As of the date of this
Agreement and the date of the Registration Statements, the Company
satisfies the eligibility requirements in existence prior to October
21, 1992 for the use of a registration statement on Form S-3 for the
offering of the Offered Securities.
3. Purchase, Sale and Delivery of Offered Securities. On the basis of
the representations, warranties and agreements and subject to the terms and
conditions set forth herein, the Company agrees to sell to the Underwriter, and
the Underwriter agrees to purchase from the Company, at a purchase price of
$4.65 per share, the Firm Securities.
The Company will deliver the Firm Securities to the Underwriter in a
form reasonably acceptable to the Underwriter against payment of the purchase
price by the Underwriter in Federal (same day) funds by wire transfer to an
account at a bank designated by the Company at 9:00 A.M., New York time, on
October 25, 2006, or at such other time not later than seven full business days
thereafter as the Underwriter and the Company determine, such time being herein
referred to as the "FIRST CLOSING DATE". For purposes of Rule 15c6-1 under the
Securities Exchange Act of 1934, the First Closing Date (if later than the
otherwise applicable settlement date) shall be
12
the settlement date for payment of funds and delivery of securities for all the
Offered Securities sold pursuant to the offering.
In addition, upon written notice from the Underwriter given to the
Company from time to time not more than 30 days subsequent to the date of the
Final Prospectuses, the Underwriter may purchase all or less than all of the
Optional Securities at the purchase price per Security to be paid for the Firm
Securities. The Company agrees to sell to the Underwriter the number of shares
of Optional Securities specified in such notice and the Underwriter agrees to
purchase such Optional Securities. Such Optional Securities may be purchased by
the Underwriter only for the purpose of covering over-allotments made in
connection with the sale of the Firm Securities. No Optional Securities shall be
sold or delivered unless the Firm Securities previously have been, or
simultaneously are, sold and delivered. The right to purchase the Optional
Securities or any portion thereof may be exercised from time to time and to the
extent not previously exercised may be surrendered and terminated at any time
upon notice by the Underwriter to the Company.
Each time for the delivery of and payment for the Optional Securities,
being herein referred to as an "OPTIONAL CLOSING DATE", which may be the First
Closing Date (the First Closing Date and each Optional Closing Date, if any,
being sometimes referred to as a "CLOSING DATE"), shall be determined by the
Underwriter but shall be not later than five full business days after written
notice of election to purchase Optional Securities is given. The Company will
deliver the Optional Securities being purchased on each Optional Closing Date to
or as instructed by the Underwriter in a form reasonably acceptable to the
Underwriter against payment of the purchase price therefor in Federal (same day)
funds by wire transfer to an account at a bank designated by the Company.
4. Offering by Underwriter. It is understood that the Underwriter
proposes to offer the Offered Securities for sale to the public as set forth in
the General Disclosure Package.
5. Certain Agreements of the Company. The Company agrees with the
Underwriter that it will furnish to counsel for the Underwriter one signed copy
of the registration statement relating to the Offered Securities, including all
exhibits, in the form it became effective and of all amendments thereto and
that, in connection with the offering of Offered Securities:
(a) Filing of Prospectuses. The Company has filed or will file
each Statutory Prospectus (including the Final Prospectuses) pursuant
to and in accordance with Rule 424(b)(2) (or, if applicable and
consented to by the Underwriter, subparagraph (5)) not later than the
second business day following the earlier of the date it is first used
or the date of this Agreement. The Company has complied and will comply
with Rule 433.
(b) Filing of Amendments; Response to Commission Requests. The
Company will promptly advise the Underwriter of any proposal to amend
or supplement the Registration Statements or any Statutory Prospectus
at any time and will afford the Underwriter a reasonable opportunity to
comment on any such proposed amendment or supplement; and the Company
will also advise the Underwriter promptly of (i) the filing of any such
13
amendment or supplement, (ii) any request by the Commission or its
staff for any amendment to any Registration Statements, for any
supplement to any Statutory Prospectus or for any additional
information, (iii) the institution by the Commission of any stop order
proceedings in respect of a Registration Statements or the threatening
of any proceeding for that purpose, and (iv) the receipt by the Company
of any notification with respect to the suspension of the qualification
of the Offered Securities in any jurisdiction or the institution or
threatening of any proceedings for such purpose. The Company will use
its best efforts to prevent the issuance of any such stop order or the
suspension of any such qualification and, if issued, to obtain as soon
as possible the withdrawal thereof.
(c) Continued Compliance with Securities Laws. If, at any time
when a prospectus relating to the Offered Securities is (or but for the
exemption in Rule 172 under the Act would be) required to be delivered
under the Act in connection with sales by any Underwriter or dealer,
any event occurs as a result of which the Final Prospectuses as then
amended or supplemented would include an untrue statement of a material
fact or omit to state any material fact necessary to make the
statements therein, in the light of the circumstances under which they
were made, not misleading, or if it is necessary at any time to amend
the Registration Statements or supplement the Final Prospectuses to
comply with the Act, the Company will promptly notify the Underwriter
of such event and will promptly prepare and file with the Commission
and furnish, at its own expense, to the Underwriter and the dealers and
any other dealers upon request of the Underwriter, an amendment or
supplement which will correct such statement or omission or an
amendment which will effect such compliance. Neither the Underwriter's
consent to, nor the Underwriter's delivery of, any such amendment or
supplement shall constitute a waiver of any of the conditions set forth
in Section 7 hereof.
(d) Rule 158. As soon as practicable, but not later than 16
months, after the date of this Agreement, the Company will make
generally available to its securityholders an earnings statement
covering a period of at least 12 months beginning after the date of
this Agreement and satisfying the provisions of Section 11(a) of the
Act and Rule 158.
(e) Furnishing of Prospectuses. The Company will furnish to
the Underwriter copies of the Registration Statements, including all
exhibits, any Statutory Prospectus relating to the Offered Securities,
the Final Prospectuses and all amendments and supplements to such
documents, in each case as soon as available and in such quantities as
the Underwriter reasonably requests. The Company will pay the expenses
of printing and distributing to the Underwriter all such documents.
(f) Blue Sky Qualifications. The Company will use reasonable
best efforts to arrange for the qualification of the Offered Securities
for sale under the laws of such jurisdictions as the Underwriter
designates and will continue such qualifications in effect so long as
required for the distribution; provided that the Company will not be
required to qualify as a foreign corporation or to file a general
consent to service of process in any such
14
jurisdiction or take any action that would subject it to taxation in
any such jurisdiction where it is not then so subject.
(g) Reporting Requirements. During the period of three years
after the date of this Agreement, the Company will furnish to the
Underwriter as soon as practicable after the end of each fiscal year, a
copy of its annual report to stockholders for such year; and the
Company will furnish to the Underwriter (i) as soon as available, a
copy of each report and any definitive proxy statement of the Company
filed with the Commission under the Exchange Act or mailed to
stockholders, and (ii) from time to time, such other information
concerning the Company as the Underwriter may reasonably request.
However, so long as the Company is subject to the reporting
requirements of either Section 13 or Section 15(d) of the Exchange Act
and is timely filing reports with the Commission on its Electronic Data
Gathering, Analysis and Retrieval system ("XXXXX"), it is not required
to furnish such reports or statements to the Underwriter.
(h) Payment of Expenses. The Company will pay all expenses
incident to the performance of its obligations under this Agreement,
including but not limited to any filing fees and other expenses
(including fees and disbursements of counsel to the Underwriter not to
exceed $1,500) incurred in connection with qualification of the Offered
Securities for sale under the laws of such jurisdictions as the
Underwriter may designate and the preparation and printing of memoranda
relating thereto, for any costs and expenses related to, the review by
the National Association of Securities Dealers, Inc. of the Offered
Securities (including filing fees and the fees and expenses of counsel
for the Underwriter relating to such review), any travel expenses of
the Company's officers and employees and any other expenses of the
Company, fees and expenses incident to listing the Offered Securities
on The NASDAQ Stock Market and other national and foreign exchanges,
fees and expenses in connection with the registration of the Offered
Securities under the Exchange Act, and expenses incurred in
distributing any Statutory Prospectuses and the Final Prospectuses
(including any amendments and supplements thereto) to the Underwriter
and for expenses incurred for preparing, printing and distributing any
Issuer Free Writing Prospectuses to investors or prospective investors.
(i) Use of Proceeds. The Company will use the net proceeds
received in connection with any offering of Offered Securities in the
manner described in the "Use of Proceeds" section of the General
Disclosure Package and, except as disclosed in the General Disclosure
Package, the Company does not intend to use any of the proceeds from
the sale of the Offered Securities hereunder to repay any outstanding
debt owed to any affiliate of the Underwriter.
(j) Absence of Manipulation. The Company will not take,
directly or indirectly, any action designed to or that would constitute
or that might reasonably be expected to cause or result in,
stabilization or manipulation of the price of any securities of the
Company to facilitate the sale or resale of the Offered Securities.
15
(k) Restriction on Sale of Securities. For the period
specified below (the "LOCK-UP PERIOD"), the Company will not, directly
or indirectly, take any of the following actions with respect to its
Common Stock or any securities convertible into or exchangeable or
exercisable for its Common Stock ("LOCK-UP SECURITIES"): (i) offer,
sell, issue, contract to sell, pledge or otherwise dispose of, Lock-Up
Securities, (ii) offer, sell, issue, contract to sell, contract to
purchase or grant any option, right or warrant to purchase Lock-Up
Securities, (iii) enter into any swap, hedge or any other agreement
that transfers, in whole or in part, the economic consequences of
ownership of Lock-Up Securities, (iv) establish or increase a put
equivalent position or liquidate or decrease a call equivalent position
in Lock-Up Securities within the meaning of Section 16 of the Exchange
Act or (v) file with the Commission a registration statement under the
Act relating to Lock-Up Securities, or publicly disclose the intention
to take any such action, without the prior written consent of the
Underwriter, except issuances of Lock-Up Securities pursuant to the
conversion of convertible securities or the exercise of warrants or
options, in each case outstanding on the date of this Agreement, grants
of employee stock options or shares issued pursuant to the terms of an
employee stock purchase plan in effect on the date of this Agreement,
or issuances of Lock-Up Securities pursuant to the exercise of such
options. The initial Lock-Up Period will commence on the date hereof
and continue for 90 days after the date of the commencement of the
public offering of the Offered Securities or such earlier date that the
Underwriter consents to in writing; provided, however, that if (1)
during the last 17 days of the initial Lock-Up Period, the Company
releases earnings results or material news or a material event relating
to the Company occurs or (2) prior to the expiration of the initial
Lock-Up Period, the Company announces that it will release earnings
results during the 16-day period beginning on the last day of the
initial Lock-Up Period, then in each case the Lock-Up Period will be
extended until the expiration of the 18-day period beginning on the
date of release of the earnings results or the occurrence of the
materials news or material event, as applicable, unless the Underwriter
waives, in writing, such extension. The Company will provide the
Underwriter with notice of any announcement described in clause (2) of
the preceding sentence that gives rise to an extension of the Lock-Up
Period.
6. Free Writing Prospectuses. The Company represents and agrees that,
unless it obtains the prior consent of the Underwriter, and the Underwriter
represents and agrees that, unless it obtains the prior consent of the Company,
it has not made and will not make any offer relating to the Offered Securities
that would constitute an Issuer Free Writing Prospectus, or that would otherwise
constitute a "free writing prospectus," as defined in Rule 405, required to be
filed with the Commission. Any such free writing prospectus consented to by the
Company and the Underwriter is hereinafter referred to as a "Permitted Free
Writing Prospectus." The Company represents that it has treated and agrees that
it will treat each Permitted Free Writing Prospectus as an "issuer free writing
prospectus," as defined in Rule 433, and has complied and will comply with the
requirements of Rules 164 and 433 applicable to any Permitted Free Writing
Prospectus, including timely Commission filing where required, legending and
record keeping.
16
7. Conditions of the Obligations of the Underwriter. The obligations of
the Underwriter to purchase and pay for the Firm Securities on the First Closing
Date and the Optional Securities to be purchased on each Optional Closing Date
will be subject to the accuracy of the representations and warranties of the
Company herein (as though made on such Closing Date), to the accuracy of the
statements of Company officers made pursuant to the provisions hereof, to the
performance by the Company of its obligations hereunder and to the following
additional conditions precedent:
(a) Accountants' Comfort Letter. The Underwriter shall have
received letters, dated, respectively, the date hereof and each Closing
Date, of Deloitte & Touche LLP confirming that they are a registered
public accounting firm and independent public accountants within the
meaning of the Securities Laws and containing statements and
information of the type ordinarily included in accountants' "comfort
letters" to underwriters with respect to the financial statements and
certain financial information contained in the Registration Statements,
the General Disclosure Package and the Final Prospectuses.
(b) Filing of Prospectuses. The Final Prospectuses shall have
been filed with the Commission in accordance with the Rules and
Regulations and Section 5(a) hereof. No stop order suspending the
effectiveness of the Registration Statements or of any part thereof
shall have been issued and no proceedings for that purpose shall have
been instituted or, to the knowledge of the Company or the Underwriter,
shall be contemplated by the Commission.
(c) No Material Adverse Change. Subsequent to the execution
and delivery of this Agreement, there shall not have occurred (i) any
change, or any development or event involving a prospective change, in
the condition (financial or otherwise), results of operations,
business, properties or prospects of the Company and its subsidiaries
taken as a whole which, in the judgment of the Underwriter, is material
and adverse and makes it impractical or inadvisable to market the
Offered Securities; (ii) any downgrading in the rating of any debt
securities of the Company by any "nationally recognized statistical
rating organization" (as defined for purposes of Rule 436(g)), or any
public announcement that any such organization has under surveillance
or review its rating of any debt securities of the Company (other than
an announcement with positive implications of a possible upgrading, and
no implication of a possible downgrading, of such rating) or any
announcement that the Company has been placed on negative outlook;
(iii) any change in U.S. or international financial, political or
economic conditions or currency exchange rates or exchange controls,
the effect of which is such as to make it, in the judgment of the
Underwriter, impractical to market or to enforce contracts for the sale
of the Offered Securities, whether in the primary market or in respect
of dealings in the secondary market; (iv) any suspension or material
limitation of trading in securities generally on the New York Stock
Exchange, or any setting of minimum or maximum prices for trading on
such exchange; (v) or any suspension of trading of any securities of
the Company on any exchange or in the over-the-counter market; (vi) any
banking moratorium declared by any U.S. federal or New York
authorities; (vii) any major disruption of settlements of securities,
17
payment, or clearance services in the United States or any other
country where such securities are listed or (viii) any attack on,
outbreak or escalation of hostilities or act of terrorism involving the
United States, any declaration of war by Congress or any other national
or international calamity or emergency if, in the judgment of the
Underwriter, the effect of any such attack, outbreak, escalation, act,
declaration, calamity or emergency is such as to make it impractical or
inadvisable to market the Offered Securities or to enforce contracts
for the sale of the Offered Securities.
(d) Opinion of Counsel for the Company. The Underwriter shall
have received an opinion, dated such Closing Date, of Mintz, Levin,
Cohn, Ferris, Glovsky & Popeo, counsel for the Company, to the effect
set forth in Exhibit A hereto.
(e) Opinion of Counsel for the Company. The Underwriter shall
have received an opinion, dated such Closing Date, of Xxxxx X.
Xxxxxxxx, Esq., Senior Vice President and Chief Patent Counsel of the
Company, to the effect set forth in Exhibit B hereto.
(f) Opinion of Counsel for the Underwriter. The Underwriter
shall have received from Xxxxx Xxxx & Xxxxxxxx, counsel for the
Underwriter, such opinion or opinions, dated such Closing Date, with
respect to such matters as the Underwriter may require, and the Company
shall have furnished to such counsel such documents as they request for
the purpose of enabling them to pass upon such matters.
(g) Officer's Certificate. The Underwriter shall have received
a certificate, dated the Closing Date, of an executive officer of the
Company and a principal financial or accounting officer of the Company
in which such officers shall state that: the representations and
warranties of the Company in this Agreement are true and correct; the
Company has complied in all material respects with all agreements and
satisfied all conditions on its part to be performed or satisfied
hereunder at or prior to the Closing Date; no stop order suspending the
effectiveness of the Registration Statement or of any part thereof has
been issued and no proceedings for that purpose have been instituted
or, to the best of their knowledge and after reasonable investigation,
are contemplated by the Commission; and subsequent to the date of the
most recent financial statements in the General Disclosure Package,
there has been no material adverse change, nor any development or event
involving a prospective material adverse change, in the condition
(financial or otherwise), results of operations, business, properties
or prospects of the Company and its subsidiaries taken as a whole
except as set forth in the General Disclosure Package or as described
in such certificate.
(h) Lock-up Agreements. On or prior to the date hereof, the
Underwriter shall have received lockup letters from each of the
executive officers and directors of the Company in substantially the
form of Exhibit C hereto.
The Company will furnish the Underwriter with such conformed copies of such
opinions, certificates, letters and documents as the Underwriter may reasonably
request. The Underwriter
18
may in its sole discretion waive compliance with any conditions to the
obligations of the Underwriter under this Agreement.
8. Indemnification and Contribution. (a) Indemnification of
Underwriter. The Company will indemnify and hold harmless the Underwriter, its
partners, members, directors, officers, employees, agents, affiliates and each
person, if any, who controls the Underwriter within the meaning of Section 15 of
the Act or Section 20 of the Exchange Act (each, an "INDEMNIFIED PARTY"),
against any and all losses, claims, damages or liabilities, joint or several, to
which such Indemnified Party may become subject, under the Act, the Exchange
Act, other Federal or state statutory law or regulation or otherwise, insofar as
such losses, claims, damages or liabilities (or actions in respect thereof)
arise out of or are based upon any untrue statement or alleged untrue statement
of any material fact contained in any part of the Registration Statements at any
time, any Statutory Prospectus as of any time, the Final Prospectuses or any
Issuer Free Writing Prospectus, or arise out of or are based upon the omission
or alleged omission of a material fact required to be stated therein or
necessary to make the statements therein, in light of the circumstances in which
they were made, not misleading, and will reimburse each Indemnified Party for
any legal or other expenses reasonably incurred by such Indemnified Party in
connection with investigating or defending against any such loss, claim, damage,
liability, action, litigation, investigation or proceeding whatsoever (whether
or not such Indemnified Party is a party thereto), whether threatened or
commenced, and in connection with the enforcement of this provision with respect
to any of the above as such expenses are incurred; provided, however, that the
Company will not be liable in any such case to the extent that any such loss,
claim, damage or liability arises out of or is based upon an untrue statement or
alleged untrue statement in or omission or alleged omission from any of such
documents in reliance upon and in conformity with written information furnished
to the Company by the Underwriter specifically for use therein, it being
understood and agreed that the only such information furnished by the
Underwriter consists of the information described as such in subsection (b)
below.
(b) Indemnification of Company. The Underwriter will severally and not
jointly indemnify and hold harmless the Company, each of its directors and each
of its officers who signs the Registration Statement and each person, if any,
who controls the Company within the meaning of Section 15 of the Act or Section
20 of the Exchange Act (each, an "UNDERWRITER INDEMNIFIED PARTY"), against any
losses, claims, damages or liabilities to which such Underwriter Indemnified
Party may become subject, under the Act, the Exchange Act, other Federal or
state statutory law or regulation or otherwise, insofar as such losses, claims,
damages or liabilities (or actions in respect thereof) arise out of or are based
upon any untrue statement or alleged untrue statement of any material fact
contained in any part of the Registration Statements at any time, any Statutory
Prospectuses as of any time, the Final Prospectuses or any Issuer Free Writing
Prospectus, or arise out of or are based upon the omission or the alleged
omission of a material fact required to be stated therein or necessary to make
the statements therein, in light of the circumstances in which they were made,
not misleading, in each case to the extent, but only to the extent, that such
untrue statement or alleged untrue statement or omission or alleged omission was
made in reliance upon and in conformity with written information furnished to
the Company by the Underwriter specifically for use therein, and will reimburse
any legal or other expenses reasonably incurred by
19
such Underwriter Indemnified Party in connection with investigating or defending
against any such loss, claim, damage, liability, action, litigation,
investigation or proceeding whatsoever (whether or not such Underwriter
Indemnified Party is a party thereto), whether threatened or commenced, based
upon any such untrue statement or omission, or any such alleged untrue statement
or omission as such expenses are incurred, it being understood and agreed that
the only such information furnished by any Underwriter consists of the
information in the second, ninth, tenth and twelfth paragraphs under the heading
"Underwriting" in the Statutory Prospectuses at the Applicable Time and the
Final Prospectuses.
(c) Actions against Parties; Notification. Promptly after receipt by an
indemnified party under this Section of notice of the commencement of any
action, such indemnified party will, if a claim in respect thereof is to be made
against the indemnifying party under subsection (a) or (b) above, notify the
indemnifying party of the commencement thereof; but the failure to notify the
indemnifying party shall not relieve it from any liability that it may have
under subsection (a) or (b) above except to the extent that it has been
materially prejudiced (through the forfeiture of substantive rights or defenses)
by such failure; and provided further that the failure to notify the
indemnifying party shall not relieve it from any liability that it may have to
an indemnified party otherwise than under subsection (a) or (b) above. In case
any such action is brought against any indemnified party and it notifies the
indemnifying party of the commencement thereof, the indemnifying party will be
entitled to participate therein and, to the extent that it may wish, jointly
with any other indemnifying party similarly notified, to assume the defense
thereof, with counsel satisfactory to such indemnified party (who shall not,
except with the consent of the indemnified party, be counsel to the indemnifying
party), and after notice from the indemnifying party to such indemnified party
of its election so to assume the defense thereof, the indemnifying party will
not be liable to such indemnified party under this Section for any legal or
other expenses subsequently incurred by such indemnified party in connection
with the defense thereof other than reasonable costs of investigation. No
indemnifying party shall, without the prior written consent of the indemnified
party, effect any settlement of any pending or threatened action in respect of
which any indemnified party is or could have been a party and indemnity could
have been sought hereunder by such indemnified party unless such settlement (i)
includes an unconditional release of such indemnified party from all liability
on any claims that are the subject matter of such action and (ii) does not
include a statement as to, or an admission of, fault, culpability or a failure
to act by or on behalf of an indemnified party.
(d) Contribution. If the indemnification provided for in this Section
is unavailable or insufficient to hold harmless an indemnified party under
subsection (a) or (b) above, then each indemnifying party shall contribute to
the amount paid or payable by such indemnified party as a result of the losses,
claims, damages or liabilities referred to in subsection (a) or (b) above (i) in
such proportion as is appropriate to reflect the relative benefits received by
the Company on the one hand and the Underwriter on the other from the offering
of the Offered Securities or (ii) if the allocation provided by clause (i) above
is not permitted by applicable law, in such proportion as is appropriate to
reflect not only the relative benefits referred to in clause (i) above but also
the relative fault of the Company on the one hand and the Underwriter on the
other in connection with the statements or omissions which resulted in such
losses, claims, damages or liabilities as
20
well as any other relevant equitable considerations. The relative benefits
received by the Company on the one hand and the Underwriter on the other shall
be deemed to be in the same proportion as the total net proceeds from the
offering (before deducting expenses) received by the Company bear to the total
underwriting discounts and commissions received by the Underwriter. The relative
fault shall be determined by reference to, among other things, whether the
untrue or alleged untrue statement of a material fact or the omission or alleged
omission to state a material fact relates to information supplied by the Company
or the Underwriter and the parties' relative intent, knowledge, access to
information and opportunity to correct or prevent such untrue statement or
omission. The amount paid by an indemnified party as a result of the losses,
claims, damages or liabilities referred to in the first sentence of this
subsection (d) shall be deemed to include any legal or other expenses reasonably
incurred by such indemnified party in connection with investigating or defending
any action or claim which is the subject of this subsection (d). Notwithstanding
the provisions of this subsection (d), the Underwriter shall be required to
contribute any amount in excess of the amount by which the total price at which
the Offered Securities underwritten by it and distributed to the public were
offered to the public exceeds the amount of any damages which the Underwriter
has otherwise been required to pay by reason of such untrue or alleged untrue
statement or omission or alleged omission. No person guilty of fraudulent
misrepresentation (within the meaning of Section 11(f) of the Act) shall be
entitled to contribution from any person who was not guilty of such fraudulent
misrepresentation. The Company and the Underwriter agree that it would not be
just and equitable if contribution pursuant to this Section 8(d) were determined
by pro rata allocation or by any other method of allocation which does not take
account of the equitable considerations referred to in this Section 8(d).
(e) Control Persons. The obligations of the Company under this Section
shall be in addition to any liability which the Company may otherwise have and
shall extend, upon the same terms and conditions, to each person, if any, who
controls the Underwriter within the meaning of the Act; and the obligations of
the Underwriter under this Section shall be in addition to any liability which
the Underwriter may otherwise have and shall extend, upon the same terms and
conditions, to each director of the Company, to each officer of the Company who
has signed the Registration Statement and to each person, if any, who controls
the Company within the meaning of the Act.
9. Survival of Certain Representations and Obligations. The respective
indemnities, agreements, representations, warranties and other statements of the
Company or its officers and of the Underwriter set forth in or made pursuant to
this Agreement will remain in full force and effect, regardless of any
investigation, or statement as to the results thereof, made by or on behalf of
the Underwriter, the Company or any of their respective representatives,
officers or directors or any controlling person, and will survive delivery of
and payment for the Offered Securities. If the purchase of the Offered
Securities by the Underwriter is not consummated by reason of any failure,
refusal or inability on the part of the Company to perform any agreement
required on its part to be performed, or because any other condition of the
Underwriter's obligations hereunder required to be fulfilled by the Company is
not fulfilled, the Company will reimburse the Underwriter for all out-of-pocket
expenses (including fees and disbursements of counsel) reasonably incurred by
the
21
Underwriter in connection with the offering of the Offered Securities, and
the respective obligations of the Company and the Underwriter pursuant to
Section 8 hereof shall remain in effect. In addition, if any Offered Securities
have been purchased under this Agreement, the representations and warranties in
Section 2 hereof and all obligations under Section 5 hereof shall also remain in
effect.
10. Notices. All communications hereunder will be in writing and, if
sent to the Underwriter, will be mailed, delivered or telegraphed and confirmed
to them at Eleven Xxxxxxx Xxxxxx, Xxx Xxxx, XX 00000-0000, Attention: LCD-IBD
or, if sent to the Company, will be mailed, delivered or telegraphed and
confirmed to it at 00 Xxxxxxxxx Xxxxxx, Xxxxxxxxx, XX 00000, Attention: Chief
Financial Officer.
11. Successors. This Agreement will inure to the benefit of and be
binding upon parties hereto and their respective successors and the officers and
directors and controlling persons referred to in Section 8, and no other person
will have any right or obligation hereunder.
12. Counterparts. This Agreement may be executed in any number of
counterparts, each of which shall be deemed to be an original, but all such
counterparts shall together constitute one and the same Agreement.
13. Absence of Fiduciary Relationship. The Company acknowledges and
agrees that:
(a) No Other Relationship. The Underwriter has been retained solely to
act as underwriter in connection with the sale of Offered Securities and that no
fiduciary, advisory or agency relationship between the Company and the
Underwriter has been created in respect of any of the transactions contemplated
by this Agreement or the Final Prospectuses, irrespective of whether the
Underwriter has advised or is advising the Company on other matters;
(b) Arm's-Length Negotiations. The price of the Offered Securities set
forth in this Agreement was established by the Company following discussions and
arms-length negotiations with the Underwriter and the Company is capable of
evaluating and understanding and understands and accepts the terms, risks and
conditions of the transactions contemplated by this Agreement;
(c) Absence of Obligation to Disclose. The Company has been advised
that the Underwriter and its affiliates are engaged in a broad range of
transactions which may involve interests that differ from those of the Company
and that the Underwriter has no obligation to disclose such interests and
transactions to the Company by virtue of any fiduciary, advisory or agency
relationship; and
(d) Waiver. The Company waives, to the fullest extent permitted by law,
any claims it may have against the Underwriter for breach of fiduciary duty or
alleged breach of fiduciary duty and agrees that the Underwriter shall have no
liability (whether direct or indirect) to the Company in respect of such a
fiduciary duty claim or to any person asserting a fiduciary duty
22
claim on behalf of or in right of the Company, including stockholders, employees
or creditors of the Company.
14. APPLICABLE LAW. THIS AGREEMENT SHALL BE GOVERNED BY, AND CONSTRUED
IN ACCORDANCE WITH, THE LAWS OF THE STATE OF NEW YORK.
The Company hereby submits to the non-exclusive jurisdiction of the
Federal and state courts in the Borough of Manhattan in The City of New York in
any suit or proceeding arising out of or relating to this Agreement or the
transactions contemplated thereby. The Company irrevocably and unconditionally
waives any objection to the laying of venue of any suit or proceeding arising
out of or relating to this Agreement or the transactions contemplated thereby in
Federal and state courts in the Borough of Manhattan in The City of New York and
irrevocably and unconditionally waives and agrees not to plead or claim in any
such court that any such suit or proceeding in any such court has been brought
in an inconvenient forum.
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23
If the foregoing is in accordance with the Underwriter's understanding of our
agreement, kindly sign and return to the Company one of the counterparts hereof,
whereupon it will become a binding agreement between the Company and the
Underwriter in accordance with its terms.
Very truly yours,
ARIAD PHARMACEUTICALS, INC.
By: /s/ Xxxxxx X. Xxxxxxxxxx
------------------------------------
Name: Xxxxxx X. Xxxxxxxxxx
Title: Senior Vice President, Finance
and Corporate Operations, Chief
Financial Officer
The foregoing Underwriting Agreement is hereby
confirmed and accepted as of the
date first above written.
CREDIT SUISSE SECURITIES (USA) LLC
By: /s/ Xxxxx X. Xxxxxx
----------------------------------
Name:
Title:
24
EXHIBIT A
FORM OF OPINION OF
MINTZ, LEVIN, COHN, FERRIS, GLOVSKY & POPEO, P.C.
25
EXHIBIT B
FORM OF OPINION OF XXXXX X. XXXXXXXX, ESQ.,
SENIOR VICE PRESIDENT AND CHIEF PATENT COUNSEL OF THE COMPANY
26
EXHIBIT C
FORM OF LOCK-UP AGREEMENT
27
