EXHIBIT 7.11
Execution Copy
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REGENERON PHARMACEUTICALS, INC.
(a New York corporation)
7,000,000 Shares of Common Stock
PURCHASE AGREEMENT
Dated: March 19, 2001
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Table of Contents
Page
SECTION 1. Representations and Warranties.................................................................... 3
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(a) Representations and Warranties by the Company.............................................. 3
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(i) Compliance with Registration Requirements......................................... 3
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(ii) Incorporated Documents............................................................ 5
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(iii) Independent Accountants........................................................... 5
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(iv) Financial Statements.............................................................. 5
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(v) No Material Adverse Change in Business............................................ 5
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(vi) Good Standing of the Company...................................................... 5
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(vii) Good Standing of Subsidiaries..................................................... 6
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(viii) Capitalization.................................................................... 6
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(ix) Authorization of Agreement........................................................ 6
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(x) Authorization and Description of Securities....................................... 6
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(xi) Absence of Defaults and Conflicts................................................. 6
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(xii) Absence of Labor Dispute.......................................................... 7
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(xiii) Absence of Proceedings............................................................ 7
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(xiv) Accuracy of Exhibits.............................................................. 8
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(xv) Possession of Intellectual Property............................................... 8
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(xvi) Absence of Further Requirements................................................... 8
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(xvii) Possession of Licenses and Permits................................................ 8
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(xviii) Title to Property................................................................. 8
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(xix) Environmental Laws................................................................ 9
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(xx) Investment Company Act............................................................ 10
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(xxi) FDA and PTO Proceedings........................................................... 10
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(b) Representations and Warranties by the Selling Shareholder.................................. 10
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(i) Accurate Disclosure............................................................... 10
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(ii) Authorization of Agreements....................................................... 10
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(iii) Security Entitlement.............................................................. 10
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(iv) Absence of Manipulation........................................................... 11
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(v) Absence of Further Requirements................................................... 11
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(vi) No Association with NASD.......................................................... 11
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(c) Officer's Certificates..................................................................... 11
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SECTION 2. Sale and Delivery to Underwriters; Closing........................................................ 11
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(a) Initial Securities and Selling Shareholder Initial Securities.............................. 11
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(b) Option Securities.......................................................................... 12
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(c) Payment.................................................................................... 12
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(d) Denominations; Registration................................................................ 13
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SECTION 3. Covenants of the Company.......................................................................... 13
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(a) Compliance with Securities Regulations and Commission Requests............................. 13
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(b) Filing of Amendments....................................................................... 14
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(c) Delivery of Registration Statements........................................................ 14
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(d) Delivery of Prospectuses................................................................... 14
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(e) Continued Compliance with Securities Laws.................................................. 14
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(f) Blue Sky Qualifications.................................................................... 15
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(g) Rule 158................................................................................... 15
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(h) Use of Proceeds............................................................................ 15
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(i) Listing.................................................................................... 15
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(j) Restriction on Sale of Securities.......................................................... 15
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(k) Reporting Requirements..................................................................... 16
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SECTION 4. Payment of Expenses............................................................................... 16
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ii
(a) Expenses................................................................................... 16
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(b) Expenses of the Selling Shareholder........................................................ 16
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(c) Termination of Agreement................................................................... 16
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(d) Allocation of Expenses..................................................................... 17
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SECTION 5. Conditions of Underwriters' Obligations........................................................... 17
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(a) Effectiveness of Registration Statement.................................................... 17
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(b) Opinion of Counsel for Company............................................................. 17
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(c) Opinion of Counsel to the Selling Shareholder.............................................. 17
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(d) Opinion of Counsel for Underwriters........................................................ 18
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(e) Officers' Certificate...................................................................... 18
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(f) Certificate of Selling Shareholder......................................................... 18
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(g) Accountants' Comfort Letter................................................................ 18
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(h) Bring-down Comfort Letter.................................................................. 19
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(i) Approval of Listing........................................................................ 19
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(j) No Objection............................................................................... 19
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(k) Lock-up Agreements......................................................................... 19
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(l) Conditions to Purchase of Option Securities................................................ 19
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(i) Officers' Certificate............................................................. 19
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(ii) Opinion of Counsel for Company.................................................... 19
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(iii) Opinion of Counsel for Underwriters............................................... 19
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(iv) Bring-down Comfort Letter......................................................... 19
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(m) Additional Documents....................................................................... 20
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(n) Termination of Agreement................................................................... 20
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SECTION 6. Indemnification................................................................................... 20
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(a) Indemnification of Underwriters............................................................ 20
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iii
(b) Indemnification of Company, Directors and Officers and Selling Shareholder................. 22
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(c) Actions against Parties; Notification...................................................... 22
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(d) Settlement without Consent if Failure to Reimburse......................................... 23
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(e) Other Agreements with Respect to Indemnification........................................... 23
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SECTION 7. Contribution...................................................................................... 23
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SECTION 8. Representations, Warranties and Agreements to Survive Delivery.................................... 25
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SECTION 9. Termination of Agreement.......................................................................... 25
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(a) Termination; General....................................................................... 25
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(b) Liabilities................................................................................ 25
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SECTION 10. Default by One or More of the Underwriters....................................................... 25
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SECTION 11. Notices.......................................................................................... 26
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SECTION 12. Parties.......................................................................................... 26
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SECTION 13. GOVERNING LAW AND TIME........................................................................... 26
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SECTION 14. Effect of Headings............................................................................... 26
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SCHEDULES
Schedule A - List of Underwriters Sch A-1
Schedule B - List of Sellers Sch B-1
Schedule C - Pricing Information Sch C-1
Schedule D - List of Persons and Entities Subject to Lock-up Sch D-1
EXHIBITS
Exhibit A-1 - Form of Opinion of General Counsel to Company A-1
Exhibit A-2 - Form of Opinion of Company's Counsel A-2
Exhibit B - Form of Opinion for Special Intellectual Property Counsel B-1
Exhibit C-1 - Form of Opinion of Counsel to Selling Shareholder C-1
Exhibit C-2 - Form of Opinion of General Counsel to Selling Shareholder C-2
Exhibit D - Form of Lock-up Letter D-1
Exhibit E - Information Provided by Selling Shareholder E-1
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REGENERON PHARMACEUTICALS, INC.
(a New York corporation)
7,000,000 Shares of Common Stock
(Par Value $0.001 Per Share)
PURCHASE AGREEMENT
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March 19, 2001
XXXXXXX XXXXX & CO.
Xxxxxxx Lynch, Pierce, Xxxxxx & Xxxxx
Incorporated
X.X. XXXXXX SECURITIES INC.
XXXXXXXXX XXXXXXXX, INC.
as Representative of the several Underwriters
x/x Xxxxxxx Xxxxx & Xx.
Xxxxxxx Lynch, Pierce, Xxxxxx & Xxxxx
Incorporated
Xxxxx Xxxxx
Xxxxx Xxxxxxxxx Xxxxxx
Xxx Xxxx, Xxx Xxxx 00000
Ladies and Gentlemen:
Regeneron Pharmaceuticals, Inc., a New York corporation (the
"Company"), and Amgen Inc., a Delaware corporation (the "Selling Shareholder"),
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confirm their respective agreements with Xxxxxxx Xxxxx & Co., Xxxxxxx Lynch,
Pierce, Xxxxxx & Xxxxx Incorporated ("Xxxxxxx Xxxxx") and each of the other
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Underwriters named in Schedule A hereto (collectively, the "Underwriters", which
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term shall also include any underwriter substituted as hereinafter provided in
Section 10 hereof), for whom Xxxxxxx Xxxxx is acting as representative (in such
capacity, the "Representative"), with respect to (i) the issue and sale by the
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Company and the sale by the Selling Shareholder, acting severally and not
jointly, and the purchase by the Underwriters, acting severally and not jointly,
of the respective numbers of shares of Common Stock, par value $0.001 per share,
of the Company ("Common Stock") set forth in said Schedule A, and (ii) the grant
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by the Company to the Underwriters, acting severally and not jointly, of the
option described in Section 2(b) hereof to purchase all or any part of 1,050,000
additional shares of Common Stock to cover over-allotments, if any. The
aforesaid 7,000,000 shares of Common Stock (the "Initial Securities") to be
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purchased by the Underwriters, of which 6,500,000 shall be issued and sold by
the Company, and of which 500,000 (the "Selling Shareholder Initial Securities")
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shall be sold by the Selling Shareholder in accordance with Schedule B hereto,
and all or any part of the 1,050,000 shares of Common Stock subject to the
option described in Section 2(b) hereof (the "Option Securities") are
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hereinafter called, collectively, the "Securities". The Company acknowledges and
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agrees that the Selling Shareholder Initial Securities are "Registrable Shares"
as defined in the Class D Convertible
Preferred Stock Purchase Agreement dated as of August 31, 1990 (the "Stock
Purchase Agreement") between the Company and the Selling Shareholder and the
Registration Rights Agreement dated as of April 15, 1996 (the "Registration
Rights Agreement") between the Company and the Selling Shareholder, that the
Selling Shareholder Initial Securities are being registered pursuant to Section
8.4 of the Stock Purchase Agreement and Section 4 of the Registration Rights
Agreement and that such Selling Shareholder is entitled to the benefits of the
Stock Purchase Agreement and the Registration Rights Agreement with respect to
such Selling Shareholder Initial Securities and the registration of the Selling
Shareholder Initial Securities.
The Company and the Selling Shareholder understand that the
Underwriters propose to make a public offering of the Securities as soon as the
Representative deems advisable after this Agreement has been executed and
delivered.
The Company has filed with the Securities and Exchange Commission (the
"Commission") a registration statement on Form S-3 (No. 333-54326) covering the
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registration of the Securities under the Securities Act of 1933, as amended (the
"1933 Act"), including the related preliminary prospectus or prospectuses.
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Promptly after execution and delivery of this Agreement, the Company will
prepare and file a prospectus in accordance with the provisions of Rule 430A
("Rule 430A") of the rules and regulations of the Commission under the 1933 Act
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(the "1933 Act Regulations") and paragraph (b) of Rule 424 ("Rule 424(b)") of
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the 1933 Act Regulations. The information included in such prospectus, that was
omitted from such registration statement at the time it became effective but
that is deemed to be part of such registration statement at the time it became
effective pursuant to paragraph (b) of Rule 430A is referred to as "Rule 430A
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Information". Each prospectus used before such registration statement became
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effective, and any prospectus that omitted, as applicable, the Rule 430A
Information, that was used after such effectiveness and prior to the execution
and delivery of this Agreement, is herein called a "preliminary prospectus."
Such registration statement, including the exhibits thereto, schedules thereto,
if any, and the documents incorporated by reference therein pursuant to Item 12
of Form S-3 under the 1933 Act, at the time it became effective and including
the Rule 430A Information, as applicable, is herein called the "Registration
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Statement". Any registration statement filed pursuant to Rule 462(b) of the 1933
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Act Regulations is herein referred to as the "Rule 462(b) Registration
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Statement", and after such filing the term "Registration Statement" shall
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include the Rule 462(b) Registration Statement. The final prospectus, including
the documents incorporated by reference therein pursuant to Item 12 of Form S-3
under the 1933 Act, in the form first furnished to the Underwriters for use in
connection with the offering of the Securities is herein called the
"Prospectus". For purposes of this Agreement, all references to the Registration
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Statement, any preliminary prospectus, the Prospectus or any amendment or
supplement to any of the foregoing shall be deemed to include the copy filed
with the Commission pursuant to its Electronic Data Gathering, Analysis and
Retrieval system ("XXXXX").
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All references in this Agreement to financial statements and schedules
and other information which is "contained", "included" or "stated" in the
Registration Statement, any preliminary prospectus or the Prospectus (or other
references of like import) shall be deemed to mean and include all such
financial statements and schedules and other information which is incorporated
by reference in the Registration Statement, any preliminary prospectus or the
Prospectus, as the case may be; and all references in this Agreement to
amendments or
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supplements to the Registration Statement, any preliminary prospectus or the
Prospectus shall be deemed to mean and include the filing of any document under
the Securities Exchange Act of 1934 (the "1934 Act") which is incorporated by
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reference in the Registration Statement, such preliminary prospectus or the
Prospectus, as the case may be.
SECTION 1. Representation and Warranties.
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(a) Representations and Warranties by the Company. The Company
represents and warrants to each Underwriter and the Selling Shareholder, as of
the date hereof, as of the Closing Time referred to in Section 2(c) hereof, and
as of each Date of Delivery (if any) referred to in Section 2(b) hereof, and
agrees with each Underwriter and the Selling Shareholder, as follows:
(i) Compliance with Registration Requirements. The Company meets the
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requirements for use of Form S-3 under the 1933 Act. Each of the
Registration Statement and any Rule 462(b) Registration Statement has
become effective under the 1933 Act and no stop order suspending the
effectiveness of the Registration Statement or any Rule 462(b) Registration
Statement has been issued under the 1933 Act and no proceedings for that
purpose have been instituted or are pending or, to the knowledge of the
Company, are contemplated by the Commission, and any request on the part of
the Commission for additional information has been complied with.
At the respective times the Registration Statement, any Rule 462(b)
Registration Statement and any post-effective amendments thereto became
effective and at the Closing Time (and, if any Option Securities are
purchased, at the Date of Delivery), the Registration Statement, the Rule
462(b) Registration Statement and any amendments and supplements thereto
complied and will comply in all material respects with the requirements of
the 1933 Act and the 1933 Act Regulations and did not and will not contain
an untrue statement of a material fact or omit to state a material fact
required to be stated therein or necessary to make the statements therein
not misleading. Neither the Prospectus nor any amendments or supplements
thereto at the time the Prospectus or any such amendment or supplement was
issued and at the Closing Time (and, if any Option Securities are
purchased, at the Date of Delivery), included or will include an untrue
statement of a material fact or omitted or will omit to state a material
fact necessary in order to make the statements therein, in the light of the
circumstances under which they were made, not misleading. The
representations and warranties in this subsection shall not apply to
statements in or omissions from the Registration Statement or Prospectus
made in reliance upon and in conformity with information furnished to the
Company in writing by any Underwriter through Xxxxxxx Xxxxx expressly for
use in the Registration Statement or Prospectus.
Each preliminary prospectus and the prospectus filed as part of the
Registration Statement as originally filed or as part of any amendment
thereto, or filed pursuant to Rule 424 under the 1933 Act, complied when so
filed in all material respects with the 1933 Act Regulations and each
preliminary prospectus and the Prospectus delivered to the Underwriters for
use in connection with this offering was identical to the
3
electronically transmitted copies thereof filed with the Commission
pursuant to XXXXX, except to the extent permitted by Regulation S-T.
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(ii) Incorporated Documents. The documents incorporated or
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deemed to be incorporated by reference in the Registration Statement and
the Prospectus, at the time they were or hereafter are filed with the
Commission (for so long as a prospectus is required to be delivered in
connection with the sale of the Securities), complied and will comply in
all material respects with the requirements of the 1934 Act and the rules
and regulations of the Commission thereunder (the "1934 Act Regulations"),
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and, when read together with the other information in the Prospectus, at
the time the Registration Statement became effective, at the time the
Prospectus was issued and at the Closing Time (and, if any Option
Securities are purchased, at the Date of Delivery), did not and will not
contain an untrue statement of a material fact or omit to state a material
fact required to be stated therein or necessary to make the statements
therein not misleading.
(iii) Independent Accountants. The accountants who certified the
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financial statements and supporting schedules included in the Registration
Statement are independent public accountants as required by the 1933 Act
and the 1933 Act Regulations.
(iv) Financial Statements. The financial statements included in
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the Registration Statement and the Prospectus, together with the related
schedules and notes, present fairly the respective financial positions of
the Company and Amgen-Regeneron Partners (as defined below) at the dates
indicated and the statement of operations, stockholders' equity (or
statement of changes in partners' capital, in the case of Amgen-Regeneron
Partners) and cash flows of the Company and Amgen-Regeneron Partners for
the periods specified; said financial statements have been prepared in
conformity with generally accepted accounting principles ("GAAP") applied
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on a consistent basis throughout the periods involved. The supporting
schedules, if any, included in the Registration Statement present fairly in
accordance with GAAP the information required to be stated therein. The
selected financial data and the summary financial information included in
the Prospectus present fairly the information shown therein and have been
compiled on a basis consistent with that of the audited financial
statements included in the Registration Statement.
(v) No Material Adverse Change in Business. Since the respective
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dates as of which information is given in the Registration Statement and
the Prospectus, except as otherwise stated therein, (A) there has been no
material adverse change or a development known to the Company involving a
prospective material adverse change, in the condition, financial or
otherwise, or in the earnings or business affairs of the Company, whether
or not arising in the ordinary course of business (a "Material Adverse
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Effect"), (B) there have been no transactions entered into by the Company
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or Amgen-Regeneron Partners, other than those in the ordinary course of
business, which are material with respect to the Company and Amgen--
Regeneron Partners considered as one enterprise, and (C) there has been no
dividend or distribution of any kind declared, paid or made by the Company
on any class of its capital stock.
(vi) Good Standing of the Company. The Company has been duly
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organized and is validly existing as a corporation in good standing under
the laws of the State of New York and has corporate power and authority to
own, lease and operate its properties
5
and to conduct its business as described in the Prospectus and to enter
into and perform its obligations under this Agreement; and the Company is
duly qualified as a foreign corporation to transact business and is in good
standing in each jurisdiction in which such qualification is required,
whether by reason of ownership or leasing of property or the conduct of
business, except where the failure so to qualify or be in good standing
would not result in a Material Adverse Effect.
(vii) Good Standing of Subsidiaries. The Company has no corporate
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subsidiaries. Amgen-Regeneron Partners, a Delaware general partnership
("Amgen-Regeneron Partners") formed by the Company and Amgen Inc., has been
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duly formed, is validly existing as a general partnership under the laws of
the jurisdiction of its formation, has the legal power and authority to own
its property and to conduct its business as described in the Prospectus and
is duly qualified to transact business and is in good standing in each
jurisdiction in which the conduct of its business or its ownership or
leasing of property requires such qualification, except to the extent that
the failure to be so qualified or be in good standing would not have a
Material Adverse Effect.
(viii) Capitalization. The authorized, issued and outstanding capital
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stock of the Company is as set forth in the Prospectus in the column
entitled "Actual" under the caption "Capitalization" (except for subsequent
issuances, if any, pursuant to this Agreement, pursuant to reservations,
agreements or employee benefit plans referred to in the Prospectus or
pursuant to the exercise of convertible securities or options referred to
in the Prospectus). The shares of issued and outstanding capital stock of
the Company, including the Selling Shareholder Initial Securities to be
purchased by the Underwriters from the Selling Shareholder, have been duly
authorized and validly issued and are fully paid and non-assessable; none
of the outstanding shares of capital stock of the Company, including the
Selling Shareholder Initial Securities to be purchased by the Underwriters
from the Selling Shareholder, was issued in violation of the preemptive or
other similar rights of any securityholder of the Company.
(ix) Authorization of Agreement. This Agreement has been duly
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authorized, executed and delivered by the Company.
(x) Authorization and Description of Securities. The Initial
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Securities and the Option Securities, if any, to be purchased by the
Underwriters from the Company have been duly authorized for issuance and
sale to the Underwriters pursuant to this Agreement and, when issued and
delivered by the Company pursuant to this Agreement against payment of the
consideration set forth herein, will be validly issued, fully paid and non-
assessable; the Common Stock conforms to all statements relating thereto
contained in the Prospectus and such description conforms to the rights set
forth in the instruments defining the same; and no holder of the Initial
Securities or the Option Securities, if any, will be subject to personal
liability by reason of being such a holder; and the issuances of the
Initial Securities and the Option Securities, if any, are not subject to
the preemptive or other similar rights of any securityholder of the
Company.
(xi) Absence of Defaults and Conflicts. Neither the Company nor
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Amgen-Regeneron Partners is in violation of its charter or by-laws or the
partnership agreement,
6
as the case may be, or in default in the performance or observance of any
obligation, agreement, covenant or condition contained in any contract,
indenture, mortgage, deed of trust, loan or credit agreement, note, lease
or other agreement or instrument to which the Company or Amgen-Regeneron
Partners is a party or by which it or any of them may be bound, or to which
any of the property or assets of the Company or Amgen-Regeneron Partners is
subject (collectively, "Agreements and Instruments") except for such
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defaults that would not result in a Material Adverse Effect; and the
execution, delivery and performance of this Agreement by the Company and
the consummation of the transactions contemplated herein and in the
Registration Statement (including the issuance and sale of the Initial
Securities and the Option Securities (if any) and the use of the proceeds
from the sale of the Initial Securities and the Option Securities (if any)
as described in the Prospectus under the caption "Use of Proceeds") and
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compliance by the Company with its obligations hereunder have been duly
authorized by all necessary corporate action and do not and will not,
whether with or without the giving of notice or passage of time or both,
conflict with or constitute a breach of, or default or Repayment Event (as
defined below) under, or result in the creation or imposition of any lien,
charge or encumbrance upon any property or assets of the Company or Amgen-
Regeneron Partners pursuant to, the Agreements and Instruments (except for
such conflicts, breaches or defaults or liens, charges or encumbrances that
would not result in a Material Adverse Effect), nor will such action result
in any violation of the provisions of the charter or by-laws of the Company
or the partnership agreement of Amgen-Regeneron Partners, or any applicable
law, statute, rule, regulation, judgment, order, writ or decree of any
government, government instrumentality or court, domestic or foreign,
having jurisdiction over the Company or Amgen-Regeneron Partners or any of
their assets, properties or operations except for any such violation that
could not be expected to result in a Material Adverse Effect. As used
herein, a "Repayment Event" means any event or condition which gives the
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holder of any note, debenture or other evidence of indebtedness (or any
person acting on such holder's behalf) the right to require the repurchase,
redemption or repayment of all or a portion of such indebtedness by the
Company or Amgen-Regeneron Partners.
(xii) Absence of Labor Dispute. No labor dispute with the employees
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of the Company or Amgen-Regeneron Partners exists or, to the knowledge of
the Company, is imminent, and the Company is not aware of any existing or
imminent labor disturbance by the employees of any of its or Amgen-
Regeneron Partners' principal suppliers, manufacturers, customers or
contractors, which, in either case, may reasonably be expected to result in
a Material Adverse Effect.
(xiii) Absence of Proceedings. There is no action, suit, proceeding,
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inquiry or investigation before or brought by any court or governmental
agency or body, domestic or foreign, now pending, or, to the knowledge of
the Company, threatened, against or affecting the Company or Amgen-
Regeneron Partners, which is required to be disclosed in the Registration
Statement (other than as disclosed therein), or which might reasonably be
expected to result in a Material Adverse Effect, or which might reasonably
be expected to materially and adversely affect the properties or assets
thereof or the consummation of the transactions contemplated in this
Agreement or the performance by the Company of its obligations hereunder;
the aggregate of all pending legal or
7
governmental proceedings to which the Company or Amgen-Regeneron Partners
is a party or of which any of their respective property or assets is the
subject which are not described in the Registration Statement, including
ordinary routine litigation incidental to the business, could not
reasonably be expected to result in a Material Adverse Effect.
(xiv) Accuracy of Exhibits. There are no contracts or documents
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which are required to be described in the Registration Statement, the
Prospectus or the documents incorporated by reference therein or to be
filed as exhibits thereto which have not been so described and filed as
required.
(xv) Possession of Intellectual Property. The Company and Amgen-
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Regeneron Partners owns or possesses, or will use their best efforts to
acquire on reasonable terms, adequate patents, patent rights, licenses,
inventions, copyrights, know-how (including trade secrets and other
unpatented and/or unpatentable proprietary or confidential information,
systems or procedures), trademarks, service marks, trade names or other
intellectual property (collectively, "Intellectual Property") necessary to
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carry on the business now operated by them. Except as disclosed in the
Prospectus, there is no litigation or other proceeding pending or, to the
Company's knowledge, threatened and no claims are presently being asserted
by any third party challenging or questioning the ownership, validity,
enforceability of the Company's or Amgen-Regeneron Partners' right to use
or own any Intellectual Property or asserting that the use of any
Intellectual Property by the Company or Amgen-Regeneron Partners or the
operation of the business of the Company or Amgen-Regeneron Partners
infringes upon or misappropriates the Intellectual Property of any third
party, other than infringements which would not be reasonably likely to
have a Material Adverse Effect and the Company is not otherwise aware of
any infringement of or conflict with asserted rights of others with respect
to any Intellectual Property or of any facts or circumstances which would
render any Intellectual Property invalid or inadequate to protect the
interest of the Company or Amgen-Regeneron Partners therein, and which
infringement or conflict (if the subject of any unfavorable decision,
ruling or finding) or invalidity or inadequacy, singly or in the aggregate,
would result in a Material Adverse Effect.
(xvi) Absence of Further Requirements. No filing with, or
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authorization, approval, consent, license, order, registration,
qualification or decree of, any court or governmental authority or agency
is necessary or required for the performance by the Company of its
obligations hereunder, in connection with the offering, issuance or sale of
the Securities hereunder or the consummation of the transactions
contemplated by this Agreement, except such as have been already obtained
or as may be required under the 1933 Act or the 1933 Act Regulation or
state securities laws.
(xvii) Possession of Licenses and Permits. The Company and Amgen-
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Regeneron Partners possess such permits, licenses, approvals, consents and
other authorizations (collectively, "Governmental Licenses") issued by the
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appropriate federal, state, local or foreign regulatory agencies or bodies
necessary to conduct the business now operated by them; the Company and
Amgen-Regeneron Partners are in compliance with the terms and conditions of
all such Governmental Licenses, except where the failure so to comply would
not, singly or in the aggregate, have a Material Adverse
8
Effect; all of the Governmental Licenses are valid and in full force and
effect, except when the invalidity of such Governmental Licenses or the
failure of such Governmental Licenses to be in full force and effect would
not have a Material Adverse Effect; and neither the Company nor Amgen-
Regeneron Partners has received any notice of proceedings relating to the
revocation or modification of any such Governmental Licenses which, singly
or in the aggregate, if the subject of an unfavorable decision, ruling or
finding, would result in a Material Adverse Effect.
(xviii) Title to Property. The Company and Amgen-Regeneron Partners
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have good and marketable title to all real property owned by the Company
and Amgen-Regeneron Partners and good title to all other properties owned
by them, in each case, free and clear of all mortgages, pledges, liens,
security interests, claims, restrictions or encumbrances of any kind except
such as (a) are described in the Prospectus or (b) do not, singly or in the
aggregate, materially affect the value of such property and do not
interfere with the use made and proposed to be made of such property by the
Company or Amgen-Regeneron Partners; and all of the leases and subleases
material to the business of the Company and Amgen-Regeneron Partners,
considered as one enterprise, and under which the Company or Amgen-
Regeneron Partners holds properties described in the Prospectus, are in
full force and effect, and neither the Company nor Amgen-Regeneron Partners
has any notice of any material claim of any sort that has been asserted by
anyone adverse to the rights of the Company or Amgen-Regeneron Partners
under any of the leases or subleases mentioned above, or affecting or
questioning the rights of the Company or Amgen-Regeneron Partners to the
continued possession of the leased or subleased premises under any such
lease or sublease.
(xix) Environmental Laws. Except as described in the Registration
------------------
Statement and except as would not, singly or in the aggregate, result in a
Material Adverse Effect, (A) neither the Company nor Amgen-Regeneron
Partners is in violation of any federal, state, local or foreign statute,
law, rule, regulation, ordinance, code, policy or rule of common law or any
judicial or administrative interpretation thereof, including any judicial
or administrative order, consent, decree or judgment, relating to pollution
or protection of human health, the environment (including, without
limitation, ambient air, surface water, groundwater, land surface or
subsurface strata) or wildlife, including, without limitation, laws and
regulations relating to the release or threatened release of chemicals,
pollutants, contaminants, wastes, toxic substances, hazardous substances,
petroleum or petroleum products (collectively, "Hazardous Materials") or to
-------------------
the manufacture, processing, distribution, use, treatment, storage,
disposal, transport or handling of Hazardous Materials (collectively,
"Environmental Laws"), (B) the Company and Amgen-Regeneron Partners have
------------------
all permits, authorizations and approvals required under any applicable
Environmental Laws and are each in compliance with their requirements, (C)
there are no pending or threatened administrative, regulatory or judicial
actions, suits, demands, demand letters, claims, liens, notices of
noncompliance or violation, investigation or proceedings relating to any
Environmental Law against the Company or Amgen-Regeneron Partners and (D)
there are no events or circumstances that might reasonably be expected to
form the basis of an order for clean-up or remediation, or an action, suit
or proceeding by any private party or governmental body
9
or agency, against or affecting the Company or Amgen-Regeneron Partners
relating to Hazardous Materials or any Environmental Laws.
(xx) Investment Company Act. The Company is not, and upon the
----------------------
issuance and sale of the Securities as herein contemplated and the
application of the net proceeds therefrom as described in the Prospectus
will not be, an "investment company" or an entity controlled by an
"investment company" as such terms are defined in The Investment Company
Act of 1940, as amended (the "1940 Act").
--------
(xxi) FDA and PTO Proceedings. To the Company's knowledge, except as
-----------------------
disclosed in the Prospectus, there are no rulemaking or similar proceedings
before the U.S. Food and Drug Administration, the U.S. Patent and Trademark
Office or the European Patent Office which affect or involve the Company or
Amgen-Regeneron Partners or any of the processes or products which the
Prospectus discloses the Company or Amgen-Regeneron Partners has developed,
is developing or proposes to develop or uses or proposes to use which, if
the subject of an action unfavorable to the Company or Amgen-Regeneron
Partners, could have a Material Adverse Effect.
(b) Representations and Warranties by the Selling Shareholder. The
Selling Shareholder represents and warrants to each Underwriter as of the date
hereof and as of the Closing Time and agrees with each Underwriter, as follows:
(i) Accurate Disclosure. The information set forth in Exhibit E is
-------------------
true and accurate.
(ii) Authorization of Agreements. The Selling Shareholder has the
---------------------------
full right, power and authority to enter into this Agreement and to sell,
transfer and deliver the Selling Shareholder Initial Securities hereunder. The
execution and delivery of this Agreement and the sale and delivery of the
Selling Shareholder Initial Securities and the consummation of the transactions
contemplated herein and compliance by the Selling Shareholder with its
obligations hereunder have been duly authorized by the Selling Shareholder and
do not and will not, whether with or without the giving of notice or passage of
time or both, conflict with or constitute a breach of, or default under, or
result in the creation or imposition of any tax, lien, charge or encumbrance
upon the Selling Shareholder Initial Securities or any property or assets of the
Selling Shareholder pursuant to any contract, indenture, mortgage, deed of
trust, loan or credit agreement, note, license, lease or other agreement or
instrument to which the Selling Shareholder is a party and which has been filed
as an exhibit to the Selling Shareholder's Form 10-K for the fiscal year ended
December 31, 2000, nor will such action result in any violation of the
provisions of the charter or by-laws of the Selling Shareholder, or any
applicable treaty, law, statute, rule, regulation, judgment, order, writ or
decree of any government, government instrumentality or court, domestic or
foreign, having jurisdiction over the Selling Shareholder or any of its
properties except to the extent that such action does not result in a material
adverse change in the financial condition of the Selling Shareholder.
(iii) Security Entitlement. The Selling Shareholder has full right,
--------------------
power and authority to hold and transfer its interests in its security
entitlement (within the meaning of Section 8-501 of the Uniform Commercial Code
as in effect in the State of New York (the
10
"NYUCC")) with respect to the Selling Shareholder Initial Securities to be sold
by the Selling Shareholder hereunder. Upon the payment of the purchase price for
the Selling Shareholder Initial Securities and the crediting by DTC of the
Selling Shareholder Initial Securities to the securities account of the
Representative with DTC, each of the Underwriters will acquire a valid security
entitlement (within the meaning of Section 8-501 of the NYUCC) in respect of the
Selling Shareholder Initial Securities to be purchased by it, and no action
(whether framed in conversion, replevin, constructive trust, equitable lien, or
other theory) based on an adverse claim to such Selling Shareholder Initial
Securities may be successfully asserted against the Underwriters under the
NYUCC.
(iv) Absence of Manipulation. The Selling Shareholder has not taken,
-----------------------
and will not take, directly or indirectly, any action which is designed to or
which has constituted or which might reasonably be expected to cause or result
in stabilization or manipulation of the price of any security of the Company to
facilitate the sale or resale of the Selling Shareholder Initial Securities.
(v) Absence of Further Requirements. No filing with (other than
-------------------------------
filings made pursuant to the 1934 Act), or consent, approval, authorization,
order, registration, qualification or decree of, any court or governmental
authority or agency of the United States or the States of California or New
York, is necessary or required for the performance by the Selling Shareholder of
its obligations hereunder, or in connection with the sale and delivery of the
Selling Shareholder Initial Securities hereunder or the consummation of the
transactions contemplated by this Agreement, except such as may have previously
been made or obtained or as may be required under the 1933 Act or the 1933 Act
Regulations or state securities laws.
(vi) No Association with NASD. Neither the Selling Shareholder nor any
------------------------
of its affiliates directly, or indirectly through one or more intermediaries,
controls, or is controlled by, or is under common control with, or has any other
association with (within the meaning of Article I, Section 1(m) of the By-laws
of the National Association of Securities Dealers, Inc.), any member firm of the
National Association of Securities Dealers, Inc.
(c) Officer's Certificates. Any certificate signed by any officer of
the Company delivered to the Representative, the Selling Shareholder or to
counsel for the Underwriters shall be deemed a representation and warranty by
the Company to each Underwriter and the Selling Shareholder as to the matters
covered thereby; and any certificate signed by or on behalf of the Selling
Shareholder as such and delivered to the Representative pursuant to the terms of
this Agreement shall be deemed a representation and warranty by the Selling
Shareholder to the Underwriters as to the matters covered thereby.
SECTION 2. Sale and Delivery to Underwriters; Closing.
------------------------------------------
(a) Initial Securities and Selling Shareholder Initial Securities. On
the basis of the representations and warranties herein contained and subject to
the terms and conditions herein set forth, the Company and the Selling
Shareholder, severally and not jointly, agree to sell to each Underwriter,
severally and not jointly, and each Underwriter, severally and not jointly,
agrees to purchase from the Company and the Selling Shareholder, at the price
per share set forth in Schedule C, that proportion of the number of Initial
Securities set forth in Schedule B opposite
11
the name of the Company or Selling Shareholder, as the case may be, which the
number of Initial Securities set forth in Schedule A opposite the name of such
Underwriter, plus any additional number of Initial Securities which such
Underwriter may become obligated to purchase pursuant to the provisions of
Section 10 hereof, bears to the total number of Initial Securities, subject, in
each case, to such adjustments among the Underwriters as the Representative in
its sole discretion shall make to eliminate any sales or purchases of fractional
securities.
(b) Option Securities. In addition, on the basis of the
representations and warranties herein contained and subject to the terms and
conditions herein set forth, the Company hereby grants an option to the
Underwriters, severally and not jointly, to purchase up to 1,050,000 additional
shares of Common Stock as set forth in Schedule C, at the price per share set
forth in Schedule C. The option hereby granted will expire 30 days after the
date hereof and may be exercised in whole or in part from time to time only for
the purpose of covering over-allotments which may be made in connection with the
offering and distribution of the Initial Securities upon notice by the
Representative to the Company setting forth the number of Option Securities as
to which the several Underwriters are then exercising the option and the time
and date of payment and delivery for such Option Securities. Any such time and
date of delivery (a "Date of Delivery") shall be determined by the
----------------
Representative, but shall not be earlier than three full business days prior to
or later than seven full business days after the exercise of said option, nor in
any event prior to the Closing Time, as hereinafter defined, provided, however,
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if the option hereby granted is exercised at least one business day prior to the
Closing Time, the Date of Delivery shall be the Closing Time. If the option is
exercised as to all or any portion of the Option Securities, each of the
Underwriters, acting severally and not jointly, will purchase that proportion of
the total number of Option Securities then being purchased which the number of
Initial Securities set forth in Schedule A opposite the name of such Underwriter
bears to the total number of Initial Securities, subject in each case to such
adjustments as the Representative in its discretion shall make to eliminate any
sales or purchases of fractional shares.
(c) Payment. Payment of the purchase price for the Initial Securities
to be sold by the Company and the Selling Shareholder Initial Securities, and
delivery of the certificates for the Initial Securities to be sold by the
Company shall be made at the offices of Shearman and Sterling, 000 Xxxxxxxxx
Xxxxxx, Xxx Xxxx, XX 00000, or at such other place as shall be agreed upon by
the Representative, the Company and the Selling Shareholder, at 9:00 A.M.
(Eastern time) on the third (fourth, if the pricing occurs after 4:30 P.M.
(Eastern time) on any given day) business day after the date hereof (unless
postponed in accordance with the provisions of Section 10), or such other time
not later than ten business days after such date as shall be agreed upon by the
Representative, the Company and the Selling Shareholder (such time and date of
payment and delivery being herein called "Closing Time").
------------
In addition, in the event that any or all of the Option Securities are
purchased by the Underwriters, payment of the purchase price for, and delivery
of certificates for, such Option Securities shall be made at the above-mentioned
offices, or at such other place as shall be agreed upon by the Representative
and the Company, on each Date of Delivery as specified in the notice from the
Representative to the Company.
Payment shall be made to the Company and the Selling Shareholder by
wire transfer of immediately available funds to bank accounts designated by the
Company and the
12
Selling Shareholder, as the case may be, against (i) in the case of the Company,
delivery to the Representative for the respective accounts of the Underwriters
of certificates for the Securities to be purchased by them and (ii) in the case
of the Selling Shareholder, the crediting of the Selling Shareholder Initial
Securities to the securities account of the Representative with DTC. It is
understood that each Underwriter has authorized the Representative, for its
account, to accept delivery of, receipt for, and make payment of the purchase
price for, the Initial Securities, the Selling Shareholder Initial Securities
and the Option Securities, if any, which it has agreed to purchase. Xxxxxxx
Xxxxx, individually and not as representative of the Underwriters, may (but
shall not be obligated to) make payment of the purchase price for the Initial
Securities, the Selling Shareholder Initial Securities or the Option Securities,
if any, to be purchased by any Underwriter whose funds have not been received by
the Closing Time or the relevant Date of Delivery, as the case may be, but such
payment shall not relieve such Underwriter from its obligations hereunder.
(d) Denominations; Registration. The Initial Securities to be sold by
the Company and the Option Securities, if any, shall be in such denominations
and registered in such names as the Representative may request in writing at
least one full business day before the Closing Time or the relevant Date of
Delivery, as the case may be. The certificates for the Initial Securities to be
sold by the Company and the Option Securities, if any, will be made available
for examination and packaging by the Representative in The City of New York not
later than 10:00 A.M. (Eastern time) on the business day prior to the Closing
Time or the relevant Date of Delivery, as the case may be.
SECTION 3. Covenants of the Company The Company covenants with each
-----------------------------------
Underwriter as follows:
(a) Compliance with Securities Regulations and Commission Requests.
The Company, subject to Section 3(b), will comply with the requirements of
Rule 430A, and will (for so long as a prospectus is required to be
delivered in connection with the sale of the Securities) notify the
Representative immediately, and confirm the notice in writing, (i) when any
post-effective amendment to the Registration Statement shall become
effective, or any supplement to the Prospectus or any amended Prospectus
shall have been filed, (ii) of the receipt of any comments from the
Commission regarding the Registration Statement or the Prospectus, (iii) of
any request by the Commission for any amendment to the Registration
Statement or any amendment or supplement to the Prospectus or for
additional information, and (iv) of the issuance by the Commission of any
stop order suspending the effectiveness of the Registration Statement or of
any order preventing or suspending the use of any preliminary prospectus,
or of the suspension of the qualification of the Securities for offering or
sale in any jurisdiction, or of the initiation or threatening of any
proceedings for any of such purposes. The Company will promptly effect the
filings necessary pursuant to Rule 424(b) and will take such steps as it
deems necessary to ascertain promptly whether the form of prospectus
transmitted for filing under Rule 424(b) was received for filing by the
Commission and, in the event that it was not, it will promptly file such
prospectus. The Company will make every reasonable effort to prevent the
issuance of any stop order and, if any stop order is issued, to obtain the
lifting thereof at the earliest possible moment.
13
(b) Filing of Amendments. For so long as a prospectus is required to
be delivered in connection with the sale of the Securities, the Company
will give the Representative notice of its intention to file or prepare any
amendment to the Registration Statement (including any filing under Rule
462(b)), or any amendment, supplement or revision to either the prospectus
included in the Registration Statement at the time it became effective or
to the Prospectus, whether pursuant to the 1933 Act, the 1934 Act or
otherwise, will furnish the Representative with copies of any such
documents a reasonable amount of time prior to such proposed filing or use,
as the case may be, and will not file or use any such document to which the
Representative or counsel for the Underwriters shall reasonably object.
(c) Delivery of Registration Statements. The Company has furnished or
will deliver to the Representative and counsel for the Underwriters,
without charge, one copy of the manually signed and as many conformed
copies as the Underwriters may reasonably request, of the Registration
Statement as originally filed and of each amendment thereto (including
exhibits filed therewith or incorporated by reference therein and documents
incorporated or deemed to be incorporated by reference therein) and signed
copies of all consents and certificates of experts, and will also deliver
to the Representative, without charge, a conformed copy of the Registration
Statement as originally filed and of each amendment thereto (without
exhibits) for each of the Underwriters. The copies of the Registration
Statement and each amendment thereto furnished to the Underwriters will be
identical in text to the electronically transmitted copies thereof filed
with the Commission pursuant to XXXXX, except to the extent permitted by
Regulation S-T.
(d) Delivery of Prospectuses. The Company has delivered to each
Underwriter, without charge, as many copies of each preliminary prospectus
as such Underwriter reasonably requested, and the Company hereby consents
to the use of such copies for purposes permitted by the 1933 Act. The
Company will furnish to each Underwriter, without charge, during the period
when the Prospectus is required to be delivered under the 1933 Act or the
1934 Act, such number of copies of the Prospectus (as amended or
supplemented) as such Underwriter may reasonably request. The Prospectus
and any amendments or supplements thereto furnished to the Underwriters
will be identical to the electronically transmitted copies thereof filed
with the Commission pursuant to XXXXX, except to the extent permitted by
Regulation S-T.
(e) Continued Compliance with Securities Laws. The Company will
comply with the 1933 Act and the 1933 Act Regulations and the 1934 Act and
the 1934 Act Regulations so as to permit the completion of the distribution
of the Securities as contemplated in this Agreement and in the Prospectus.
If at any time when a prospectus is required by the 1933 Act to be
delivered in connection with sales of the Securities, any event shall occur
or condition shall exist as a result of which it is necessary, in the
opinion of counsel for the Underwriters or for the Company, to amend the
Registration Statement or amend or supplement the Prospectus in order that
the Prospectus will not include any untrue statements of a material fact or
omit to state a material fact necessary in order to make the statements
therein not misleading in the light of the circumstances existing at the
time it is delivered to a purchaser, or if it shall be necessary, in the
opinion
14
of such counsel, at any such time to amend the Registration Statement or
amend or supplement the Prospectus in order to comply with the requirements
of the 1933 Act or the 1933 Act Regulations, the Company will promptly
prepare and file with the Commission, subject to Section 3(b), such
amendment or supplement as may be necessary to correct such statement or
omission or to make the Registration Statement or the Prospectus comply
with such requirements, and the Company will furnish to the Underwriters
such number of copies of such amendment or supplement as the Underwriters
may reasonably request.
(f) Blue Sky Qualifications. The Company will cooperate with the
Underwriters, to qualify the Securities for offering and sale under the
applicable securities laws of such states and other jurisdictions as the
Representative may designate and to maintain such qualifications in effect
for a period of not less than one year from the later of the effective date
of the Registration Statement and any Rule 462(b) Registration Statement;
provided, however, that the Company shall not be obligated to file any
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general consent to service of process or to qualify as a foreign
corporation or as a dealer in securities in any jurisdiction in which it is
not so qualified or to subject itself to taxation in respect of doing
business in any jurisdiction in which it is not otherwise so subject. In
each jurisdiction in which the Securities have been so qualified, the
Company will file such statements and reports as may be required by the
laws of such jurisdiction to continue such qualification in effect for a
period as required by the relevant jurisdiction of the Registration
Statement and any Rule 462(b) Registration Statement.
(g) Rule 158. The Company will timely file such reports pursuant to
the 1934 Act as are necessary in order to make generally available to its
securityholders as soon as practicable an earnings statement for the
purposes of, and to provide the benefits contemplated by, the last
paragraph of Section 11(a) of the 1933 Act.
(h) Use of Proceeds. The Company will use the net proceeds received
by it from the sale of the Securities in the manner specified in the
Prospectus under "Use of Proceeds".
(i) Listing. The Company will use its best efforts to effect and
maintain the quotation of the Securities on the Nasdaq National Market and
will file with the Nasdaq National Market all documents and notices
required by the Nasdaq National Market of companies that have securities
that are traded in the over-the-counter market and quotations for which are
reported by the Nasdaq National Market.
(j) Restriction on Sale of Securities. During a period of 90 days
from the date of the Prospectus, the Company will not, without the prior
written consent of Xxxxxxx Xxxxx, (i) directly or indirectly, offer,
pledge, sell, contract to sell, sell any option or contract to purchase,
purchase any option or contract to sell, grant any option, right or warrant
to purchase or otherwise transfer or dispose of any share of Common Stock
or any securities convertible into or exercisable or exchangeable for
Common Stock or file any registration statement under the 1933 Act with
respect to any of the foregoing or (ii) enter into any swap or any other
agreement or any transaction that transfers, in whole or in part, directly
or indirectly, the economic consequence of ownership of the Common Stock,
whether
15
any such swap or transaction described in clause (i) or (ii) above is to be
settled by delivery of Common Stock or such other securities, in cash or
otherwise. The foregoing sentence shall not apply to (A) the Securities to
be sold hereunder, (B) any shares of Common Stock issued by the Company
upon the exercise of an option or warrant or the conversion of a security
outstanding on the date hereof and referred to in the Prospectus, (C) any
shares of Common Stock issued or options to purchase Common Stock granted
pursuant to existing and future employee benefit plans of the Company or
(D) any shares of Common Stock issued pursuant to any non-employee director
stock plan or dividend reinvestment plan.
(k) Reporting Requirements. The Company, during the period when the
Prospectus is required to be delivered under the 1933 Act or the 1934 Act,
will file all documents required to be filed with the Commission pursuant
to the 1934 Act within the time periods required by the 1934 Act and the
1934 Act Regulations.
SECTION 4. Payment of Expenses
------------------------------
(a) Expenses. The Company will pay or cause to be paid all expenses
incident to the performance of its obligations under this Agreement, including
(i) the preparation, printing and filing of the Registration Statement
(including financial statements and exhibits) as originally filed and of each
amendment thereto, (ii) the preparation, printing and delivery to the
Underwriters of this Agreement, any Agreement among Underwriters and such other
documents as may be required in connection with the offering, purchase, sale,
issuance or delivery of the Securities, (iii) the preparation, issuance and
delivery of the certificates for the Securities to the Underwriters, including
any stock or other transfer taxes and any stamp or other duties payable upon the
sale, issuance or delivery of the Securities to the Underwriters, (iv) the fees
and disbursements of the Company's counsel, the Selling Shareholder's counsel,
accountants and other advisors, (v) the filing fees incident to any necessary
filings under state securities laws and the reasonable fees and disbursements of
counsel for the Underwriters in connection therewith and in connection with the
preparation of the Blue Sky Survey and any supplement thereto, (vi) the printing
and delivery to the Underwriters of copies of each preliminary prospectus, and
of the Prospectus and any amendments or supplements thereto, (vii) the fees and
expenses of the transfer agent or registrar for the Securities, (viii) the
filing fees incident to, and the reasonable fees and disbursements of counsel to
the Underwriters in connection with, the review by the National Association of
Securities Dealers, Inc. (the "NASD") of the terms of the sale of the Securities
----
and (ix) the fees and expenses incurred in connection with the inclusion of the
Securities in the Nasdaq National Market.
(b) Expenses of the Selling Shareholder.
The Selling Shareholder will pay all discounts and commissions of
the Underwriters relating to the distribution of the 500,000 shares of Selling
Shareholder Initial Securities.
(c) Termination of Agreement.
16
If this Agreement is terminated by the Representative in accordance
with the provisions of Section 5 or Section 9(a)(i) hereof, the Company shall
reimburse the Underwriters for all of their out-of-pocket expenses, including
the reasonable fees and disbursements of counsel for the Underwriters incurred
in connection with the Initial Securities, Selling Shareholder Initial
Securities and Option Securities respectively as advised by the Underwriters.
(d) Allocation of Expenses.
The provisions of this Section shall not affect the agreement between
the Company and the Selling Shareholder for the sharing of such costs and
expenses as provided in the Stock Purchase Agreement.
SECTION 5. Conditions of Underwriters' Obligations. The obligations of
---------------------------------------
the several Underwriters hereunder are subject to the accuracy of the
representations and warranties of the Company and the Selling Shareholder
contained in Section 1 hereof or in certificates of any officer of the Company
delivered pursuant to the provisions hereof, to the performance by the Company
and the Selling Shareholder of their respective covenants and other obligations
hereunder, and to the following further conditions:
(a) Effectiveness of Registration Statement. The Registration
Statement, including any Rule 462(b) Registration Statement, has become
effective and at Closing Time no stop order suspending the effectiveness of
the Registration Statement shall have been issued under the 1933 Act or
proceedings therefor initiated or threatened by the Commission, and any
request on the part of the Commission for additional information shall have
been complied with to the reasonable satisfaction of counsel to the
Underwriters. A prospectus containing the Rule 430A Information shall have
been filed with the Commission in accordance with Rule 424(b) (or a post-
effective amendment providing such information shall have been filed and
declared effective in accordance with the requirements of Rule 430A).
(b) Opinion of Counsel for Company. At Closing Time, the
Representative shall have received (i) the favorable opinion, dated as of
Closing Time, of Xxxxxx X. Xxxxxxxx, Esq., General Counsel of the Company,
(ii) the favorable opinion, dated as of Closing Time, of Skadden, Arps,
Slate, Xxxxxxx & Xxxx LLP, counsel for the Company and (iii) the favorable
opinion, dated as of Closing Time, of Xxxxxx X. Xxxxxxxxxx, in-house
intellectual property counsel for the Company, each in form and substance
satisfactory to counsel for the Underwriters, together with signed or
reproduced copies of such letter for each of the other Underwriters to the
effect set forth in Exhibit X-0, Xxxxxxx X-0 and Exhibit B, respectively,
hereto and to such further effect as counsel to the Underwriters may
reasonably request.
(c) Opinion of Counsel to the Selling Shareholder. At Closing Time,
the Representative shall have received the favorable opinions dated as of
Closing Time, of Xxxxxx & Xxxxxxx, counsel for the Selling Shareholder, and
the General Counsel of the Selling Shareholder, together with signed or
reproduced copies of such opinion for each of the other underwriters, to
the effect set forth in Exhibits C-1 and C-2 hereto.
17
(d) Opinion of Counsel for Underwriters. At Closing Time, the
Representative shall have received the favorable opinion, dated as of
Closing Time, of Shearman & Sterling, counsel for the Underwriters. In
giving such opinion such counsel may rely, as to all matters governed by
the laws of jurisdictions other than the law of the State of New York and
the federal law of the United States, upon the opinions of counsel
satisfactory to the Representative. Such counsel may also state that,
insofar as such opinion involves factual matters, they have relied, to the
extent they deem proper, upon certificates of officers of the Company and
certificates of public officials.
(e) Officers' Certificate. At Closing Time, there shall not have
been, since the date hereof or since the respective dates as of which
information is given in the Prospectus, any material adverse change or a
development known to the Company involving a prospective material adverse
change in the condition, financial or otherwise, or in the earnings or
business affairs of the Company, whether or not arising in the ordinary
course of business, and the Representative and the Selling Shareholder
shall each have received a certificate of the President or a Vice President
of the Company and of the chief financial or chief accounting officer of
the Company, dated as of Closing Time, to the effect that (i) there has
been no such material adverse change, (ii) the representations and
warranties in Section 1(a) hereof are true and correct with the same force
and effect as though expressly made at and as of Closing Time, (iii) the
Company has complied with all agreements and satisfied all conditions on
its part to be performed or satisfied at or prior to Closing Time, and (iv)
no stop order suspending the effectiveness of the Registration Statement
has been issued and no proceedings for that purpose have been instituted or
are pending or are contemplated by the Commission.
(f) Certificate of Selling Shareholder. At Closing Time, the
Representative shall have received a certificate of the Selling
Shareholder, dated as of Closing Time, to the effect that (A) the
representations and warranties of the Selling Shareholder contained in
Section 1(b) hereof are true and correct in all respects with the same
force and effect as though expressly made as of the Closing Time and (B)
the Selling Shareholder has complied in all material respects with all
agreements and all conditions on its part to be performed under this
Agreement at or prior to Closing Time.
(g) Accountants' Comfort Letter. At the time of the execution of this
Agreement, the Representative shall have received from each of
PricewaterhouseCoopers LLP and Ernst & Young LLP, a letter dated such date,
in form and substance satisfactory to the Representative, together with
signed or reproduced copies of such letter for each of the other
Underwriters containing statements and information of the type ordinarily
included in accountants' "comfort letters" to underwriters with respect to
the financial statements and certain financial information contained in the
Registration Statement and the Prospectus.
18
(h) Bring-down Comfort Letter. At Closing Time, the Representative
shall have received from each of PricewaterhouseCoopers LLP and Ernst &
Young LLP a letter, dated as of Closing Time, to the effect that they
reaffirm the statements made in the letter furnished pursuant to subsection
(g) of this Section, except that the specified date referred to shall be a
date not more than three business days prior to Closing Time.
(i) Approval of Listing. At Closing Time, the Securities shall have
been approved for inclusion in the Nasdaq National Market, subject only to
official notice of issuance.
(j) No Objection. The NASD has confirmed that it has not raised any
objection with respect to the fairness and reasonableness of the
underwriting terms and arrangements.
(k) Lock-up Agreements. At the date of this Agreement, the
Representative shall have received an agreement substantially in the form
of Exhibit C hereto signed by the persons listed on Schedule D hereto.
(l) Conditions to Purchase of Option Securities. In the event that
the Underwriters exercise their option provided in Section 2(b) hereof to
purchase all or any portion of the Option Securities, the representations
and warranties of the Company contained herein and the statements in any
certificates furnished by the Company hereunder shall be true and correct
as of each Date of Delivery and, at the relevant Date of Delivery, the
Representative shall have received:
(i) Officers' Certificate. A certificate, dated such Date of
---------------------
Delivery, of the President or a Vice President of the Company and of the
chief financial or chief accounting officer of the Company confirming that
the certificate delivered at Closing Time pursuant to Section 5(e) hereof
remains true and correct as of such Date of Delivery.
(ii) Opinion of Counsel for Company. The favorable opinions dated as
------------------------------
of Closing Time of (i) Xxxxxx X. Xxxxxxxx, Esq., General Counsel of the
Company, (ii) Skadden, Arps, Slate, Xxxxxxx & Xxxx LLP, counsel for the
Company, and (iii) Xxxxxx X. Xxxxxxxxxx, in-house intellectual property
counsel for the Company, each in form and substance satisfactory to counsel
for the Underwriters, dated such Date of Delivery, relating to the Option
Securities to be purchased on such Date of Delivery and otherwise to the
same effect as the opinion required by Section 5(b) hereof.
(iii) Opinion of Counsel for Underwriters. The favorable opinion of
-----------------------------------
Shearman & Sterling, counsel for the Underwriters, dated such Date of
Delivery, relating to the Option Securities to be purchased on such Date of
Delivery and otherwise to the same effect as the opinion required by
Section 5(d) hereof.
(iv) Bring-down Comfort Letter. A letter from each of
-------------------------
PricewaterhouseCoopers LLP and Ernst & Young, in form and substance
satisfactory to the Representative(s) and dated such Date of Delivery,
substantially in the same form and substance as the letter furnished to the
Representative pursuant to Section 5(h) hereof,
19
except that the "specified date" in the letter furnished pursuant to this
paragraph shall be a date not more than five days prior to such Date of
Delivery.
(m) Additional Documents. At Closing Time and at each Date of
Delivery, counsel for the Underwriters shall have been furnished with such
documents and opinions as they reasonably may require for the purpose of
enabling them to pass upon the issuance and sale of the Securities as
herein contemplated, or in order to evidence the accuracy of any of the
representations or warranties, or the fulfillment of any of the conditions,
herein contained; and all proceedings taken by the Company and the Selling
Shareholder in connection with the issuance and sale of the Securities as
herein contemplated shall be reasonably satisfactory in form and substance
to the Representative(s) and counsel for the Underwriters.
(n) Termination of Agreement. If any condition specified in this
Section shall not have been fulfilled when and as required to be fulfilled,
this Agreement, or, in the case of any condition to the purchase of Option
Securities, on a Date of Delivery which is after the Closing Time, the
obligations of the several Underwriters to purchase the relevant Option
Securities, may be terminated by the Representative by notice to the
Company at any time at or prior to Closing Time or such Date of Delivery,
as the case may be, and such termination shall be without liability of any
party to any other party except as provided in Section 4 and except that
Sections 1, 6, 7 and 8 shall survive any such termination and remain in
full force and effect.
SECTION 6. Indemnification.
---------------
(a) Indemnification of Underwriters.
(1) The Company agrees to indemnify and hold harmless each Underwriter and
each person, if any, who controls any Underwriter within the meaning of Section
15 of the 1933 Act or Section 20 of the 1934 Act as follows:
(i) against any and all loss, liability, claim, damage and expense
whatsoever, as incurred, arising out of any untrue statement or alleged
untrue statement of a material fact contained in the Registration Statement
(or any amendment thereto), including the Rule 430A Information, or the
omission or alleged omission therefrom of a material fact required to be
stated therein or necessary to make the statements therein not misleading
or arising out of any untrue statement or alleged untrue statement of a
material fact included in any preliminary prospectus or the Prospectus (or
any amendment or supplement thereto), or the omission or alleged omission
therefrom of a material fact necessary in order to make the statements
therein, in the light of the circumstances under which they were made, not
misleading;
(ii) against any and all loss, liability, claim, damage and expense
whatsoever, as incurred, to the extent of the aggregate amount paid in
settlement of any litigation, or any investigation or proceeding by any
governmental agency or body, commenced or threatened, or of any claim
whatsoever based upon any such untrue statement or omission, or any such
alleged untrue statement or omission; provided that (subject to
20
Section 6(d) below) any such settlement is effected with the written
consent of the Company; and
(iii) against any and all expense whatsoever, as incurred (including
the fees and disbursements of counsel chosen by Xxxxxxx Xxxxx), reasonably
incurred in investigating, preparing or defending against any litigation,
or any investigation or proceeding by any governmental agency or body,
commenced or threatened, or any claim whatsoever based upon any such untrue
statement or omission, or any such alleged untrue statement or omission, to
the extent that any such expense is not paid under (i) or (ii) above;
provided, however, that this indemnity agreement shall not apply to any loss,
-------- -------
liability, claim, damage or expense to the extent arising out of any untrue
statement or omission or alleged untrue statement or omission made in reliance
upon and in conformity with written information furnished to the Company by any
Underwriter through Xxxxxxx Xxxxx expressly for use in the Registration
Statement (or any amendment thereto), including the Rule 430A Information, or
any preliminary prospectus or the Prospectus (or any amendment or supplement
thereto); and provided, further, that the Company will not be liable to any
-------- -------
Underwriter with respect to any Prospectus to the extent that any such loss,
liability, claim, damage or expense resulted from the fact that such
Underwriter, in contravention of a requirement of this Agreement or applicable
law, sold Securities to a person to whom such Underwriter failed to send or
give, at or prior to the Closing Time, a copy of the final Prospectus, as then
amended or supplemented if the Company has previously furnished copies thereof
to the Underwriter and the loss, liability, claim, damage or expense of such
Underwriter resulted from an untrue statement or omission of a material fact
contained or omitted from the preliminary Prospectus which was corrected in the
final Prospectus, if applicable, as amended or supplemented prior to the Closing
Time, and such final Prospectus was required by law to be delivered at or prior
to the written confirmation of sale to such person.
(2) The Selling Shareholder agrees to indemnify and hold harmless each
Underwriter and each person, if any, who controls any Underwriter within the
meaning of Section 15 of the 1933 Act or Section 20 of the 1934 Act, to the same
extent as the foregoing indemnity from the Company to each Underwriter;
provided, however, that such indemnification shall be only with respect to
-------- -------
information regarding the Selling Shareholder furnished in writing to the
Company by or on behalf of the Selling Shareholder expressly for use in the
Registration Statement (or any amendment thereto), including Rule 430A
Information, if applicable, or any preliminary prospectus or Prospectus (or any
amendment or supplement thereto); and provided further, that the aggregate
-------- -------
liability of the Selling Shareholder pursuant to this paragraph shall be limited
to the total net proceeds received by the Selling Shareholder from the Selling
Shareholder Initial Securities purchased by the Underwriters from the Selling
Shareholder pursuant to this Agreement. The Underwriters agree that the
information furnished to the Company specifically for use in the Registration
Statement (or any amendment thereto), including Rule 430A Information, if
applicable, or any preliminary prospectus or Prospectus (or any amendment or
supplement thereto) includes only the information relating to the Selling
Shareholder set forth in Exhibit E hereto; and provided further that the Selling
-------- -------
Shareholder will not be liable to any Underwriter with respect to any Prospectus
to the extent that any such loss, liability, claim, damage or expense resulted
from the fact that such Underwriter, in contravention of a
21
requirement of this Agreement or applicable law, sold Securities to a person to
whom such Underwriter failed to send or give, at or prior to the Closing Time, a
copy of the final Prospectus, as then amended or supplemented if the Company has
previously furnished copies thereof to the Underwriter and the loss, liability,
claim, damage or expense of such Underwriter resulted from an untrue statement
or omission of a material fact contained in or omitted from the preliminary
prospectus which was corrected in the final Prospectus, if applicable, as
amended or supplemented prior to the Closing Time, and such final Prospectus was
required by law to be delivered at or prior to the written confirmation of sale
to such person.
(b) Indemnification of Company, Directors and Officers and Selling
Shareholder.
Each Underwriter severally agrees to indemnify and hold harmless the
Company, its directors, each of its officers who signed the Registration
Statement, and each person, if any, who controls the Company within the meaning
of Section 15 of the 1933 Act or Section 20 of the 1934 Act and the Selling
Shareholder and each person, if any, who controls the Selling Shareholder within
the meaning of section 15 of the 1933 Act or Section 20 of the 1934 Act against
any and all loss, liability, claim, damage and expense described in the
indemnity contained in subsection (a) of this Section, as incurred, but only
with respect to untrue statements or omissions, or alleged untrue statements or
omissions, made in the Registration Statement (or any amendment thereto),
including the Rule 430A Information or any preliminary prospectus or the
Prospectus (or any amendment or supplement thereto) in reliance upon and in
conformity with written information furnished to the Company by such Underwriter
through Xxxxxxx Xxxxx expressly for use in the Registration Statement (or any
amendment thereto) or such preliminary prospectus or the Prospectus (or any
amendment or supplement thereto).
(c) Actions against Parties; Notification. Each indemnified party
shall give notice as promptly as reasonably practicable to each indemnifying
party of any action commenced against it in respect of which indemnity may be
sought hereunder, but failure to so notify an indemnifying party shall not
relieve such indemnifying party from any liability hereunder to the extent it is
not materially prejudiced as a result thereof and in any event shall not relieve
it from any liability which it may have otherwise than on account of this
indemnity agreement. In the case of parties indemnified pursuant to Section 6(a)
above, counsel to the indemnified parties shall be selected by Xxxxxxx Xxxxx,
and, in the case of parties indemnified pursuant to Section 6(b) above, counsel
to the indemnified parties shall be selected by the Company or the Selling
Shareholder, as the case may be. An indemnifying party may participate at its
own expense in the defense of any such action; provided, however, that counsel
-------- -------
to the indemnifying party shall not (except with the consent of the indemnified
party) also be counsel to the indemnified party. In no event shall the
indemnifying parties be liable for fees and expenses of more than one counsel
(in addition to any local counsel) separate from their own counsel for all
indemnified parties in connection with any one action or separate but similar or
related actions in the same jurisdiction arising out of the same general
allegations or circumstances. No indemnifying party shall, without the prior
written consent of the indemnified parties, settle or compromise or consent to
the entry of any judgment with respect to any litigation, or any investigation
or proceeding by any governmental agency or body, commenced or threatened, or
any claim whatsoever in respect of which indemnification or contribution could
be sought under this Section 6 or Section 7 hereof (whether or not the
indemnified parties are actual or potential parties thereto), unless such
settlement, compromise or consent (i) includes an unconditional release of each
indemnified party from all liability arising out of such litigation,
22
investigation, proceeding or claim and (ii) does not include a statement as to
or an admission of fault, culpability or a failure to act by or on behalf of any
indemnified party.
(d) Settlement without Consent if Failure to Reimburse. If at any
time an indemnified party shall have requested an indemnifying party to
reimburse the indemnified party for fees and expenses of counsel, such
indemnifying party agrees that it shall be liable for any settlement of the
nature contemplated by Section 6(a)(1)(ii) effected without its written consent
if (i) such settlement is entered into more than 45 days after receipt by such
indemnifying party of the aforesaid request, (ii) such indemnifying party shall
have received notice of the terms of such settlement at least 30 days prior to
such settlement being entered into and (iii) such indemnifying party shall not
have reimbursed such indemnified party in accordance with such request prior to
the date of such settlement.
(e) Other Agreements with Respect to Indemnification. The provisions
of this Section shall not affect the agreement between the Company and the
Selling Shareholder with respect to indemnification as provided in the
Registration Rights Agreement.
SECTION 7. Contribution. If the indemnification provided for in
------------
Section 6 hereof is for any reason unavailable to or insufficient to hold
harmless an indemnified party in respect of any losses, liabilities, claims,
damages or expenses referred to therein, then each indemnifying party shall
contribute to the aggregate amount of such losses, liabilities, claims, damages
and expenses incurred by such indemnified party, as incurred, (i) in such
proportion as is appropriate to reflect the relative benefits received by the
Company and the Selling Shareholder, on the one hand, and the Underwriters on
the other hand, from the offering of the Securities pursuant to this Agreement
or (ii) if the allocation provided by clause (i) is not permitted by applicable
law, in such proportion as is appropriate to reflect not only the relative
benefits referred to in clause (i) above but also the relative fault of the
Company and the Selling Shareholder, on the one hand, and of the Underwriters on
the other hand, in connection with the statements or omissions which resulted in
such losses, liabilities, claims, damages or expenses, as well as any other
relevant equitable considerations.
The relative benefits received by the Company and the Selling
Shareholder on the one hand, and the Underwriters on the other hand, in
connection with the offering of the Securities pursuant to this Agreement shall
be deemed to be in the same respective proportions as the total net proceeds
from the offering of the Securities pursuant to this Agreement received by the
Company and the Selling Shareholder and the total underwriting discount received
by the Underwriters, in each case as set forth on the cover of the Prospectus
bear to the aggregate initial public offering price of the Securities as set
forth on such cover.
The relative fault of each of the Company and the Selling Shareholder
on the one hand, and the Underwriters on the other hand, shall be determined by
reference to, among other things, whether any such untrue or alleged untrue
statement of a material fact or omission or alleged omission to state a material
fact relates to information supplied by the Company or the Selling Shareholder
or by the Underwriters and the parties' relative intent, knowledge, access to
information and opportunity to correct or prevent such statement or omission.
23
The Company, the Selling Shareholder and the Underwriters agree that
it would not be just and equitable if contribution pursuant to this Section were
determined by pro rata allocation (even if the Underwriters were treated as one
entity for such purpose) or by any other method of allocation which does not
take account of the equitable considerations referred to above in this Section.
The aggregate amount of losses, liabilities, claims, damages and expenses
incurred by an indemnified party and referred to above in this Section shall be
deemed to include any legal or other expenses reasonably incurred by such
indemnified party in investigating, preparing or defending against any
litigation, or any investigation or proceeding by any governmental agency or
body, commenced or threatened, or any claim whatsoever based upon any such
untrue or alleged untrue statement or omission or alleged omission.
Notwithstanding the provisions of this Section, no Underwriter shall
be required to contribute any amount in excess of the amount by which the total
price at which the Securities underwritten by it and distributed to the public
were offered to the public exceeds the amount of any damages which such
Underwriter has otherwise been required to pay by reason of any such untrue or
alleged untrue statement or omission or alleged omission.
Notwithstanding the provisions of this Section, the Selling
Shareholder shall not be required to contribute any amount in excess of the
total net proceeds received by the Selling Shareholder from the Selling
Shareholder Initial Securities purchased by the Underwriters pursuant to this
Agreement.
No person guilty of fraudulent misrepresentation (within the meaning
of Section 11(f) of the 0000 Xxx) shall be entitled to contribution from any
person who was not guilty of such fraudulent misrepresentation.
For purposes of this Section, each person, if any, who controls an
Underwriter within the meaning of Section 15 of the 1933 Act or Section 20 of
the 1934 Act shall have the same rights to contribution as such Underwriter, and
each director of the Company, each officer of the Company who signed the
Registration Statement, and each person, if any, who controls the Company or the
Selling Shareholder within the meaning of Section 15 of the 1933 Act or Section
20 of the 1934 Act shall have the same rights to contribution as the Company or
the Selling Shareholder, as the case may be. The Underwriters' respective
obligations to contribute pursuant to this Section are several in proportion to
the number of Securities set forth opposite their respective names in Schedule A
hereto and not joint.
The provisions of this Section shall not affect the agreement between
the Company and the Selling Shareholder with respect to contribution as provided
in the Stock Purchase Agreement.
24
SECTION 8. Representations, Warranties and Agreements to Survive
-----------------------------------------------------
Delivery. All representations, warranties and agreements contained in this
--------
Agreement or in certificates of officers of the Company and the Selling
Shareholder submitted pursuant hereto shall remain operative and in full force
and effect, regardless of any investigation made by or on behalf of any
Underwriter or controlling person, or by or on behalf of the Company or the
Selling Shareholder, and shall survive delivery of the Securities to the
Underwriters.
SECTION 9. Termination of Agreement.
------------------------
(a) Termination; General. The Representative may terminate this
Agreement by notice to the Company and the Selling Shareholder at any time at or
prior to Closing Time (i) if there has been, since the time of execution of this
Agreement or since the respective dates as of which information is given in the
Prospectus, any material adverse change in the condition, financial or
otherwise, or in the earnings, business affairs or business prospects of the
Company, whether or not arising in the ordinary course of business, or (ii) if
there has occurred any material adverse change in the financial markets in the
United States or the international financial markets, any outbreak of
hostilities or escalation thereof or other calamity or crisis or any change or
development involving a prospective change in national or international
political, financial or economic conditions, in each case the effect of which is
such as to make it, in the judgment of the Representative, impracticable to
market the Securities or to enforce contracts for the sale of the Securities, or
(iii) if trading in any securities of the Company has been suspended or
materially limited by the Commission or the Nasdaq National Market, or if
trading generally on the American Stock Exchange or the New York Stock Exchange
or in the Nasdaq National Market has been suspended or materially limited, or
minimum or maximum prices for trading have been fixed, or maximum ranges for
prices have been required, by any of said exchanges or by such system or by
order of the Commission, the National Association of Securities Dealers, Inc. or
any other governmental authority, or (iv) if a banking moratorium has been
declared by either Federal or New York authorities.
(b) Liabilities. If this Agreement is terminated pursuant to this
Section, such termination shall be without liability of any party to any other
party except as provided in Section 4 hereof, and provided further that Sections
1, 6, 7 and 8 shall survive such termination and remain in full force and
effect.
SECTION 10. Default by One or More of the Underwriters. If one or more
------------------------------------------
of the Underwriters shall fail at Closing Time or a Date of Delivery to purchase
the Securities which it or they are obligated to purchase under this Agreement
(the "Defaulted Securities"), the Representative(s) shall have the right, but
--------------------
not the obligation, within 24 hours thereafter, to make arrangements for one or
more of the non-defaulting Underwriters, or any other underwriters, to purchase,
each severally and not jointly, all, but not less than all, of the Defaulted
Securities in such amounts as may be agreed upon and upon the terms herein set
forth; if, however, the Representative(s) shall not have completed such
arrangements within such 24-hour period, then this Agreement shall terminate
without liability on the part of any non-defaulting Underwriter.
No action pursuant to this Section shall relieve any defaulting
Underwriter from liability in respect of its default.
25
In the event of any such default which does not result in a
termination of this Agreement, either the Representative or the Company or the
Selling Shareholder shall have the right to postpone the Closing Time, for a
period not exceeding seven days in order to effect any required changes in the
Registration Statement or Prospectus or in any other documents or arrangements.
SECTION 11. Notices. All notices and other communications hereunder
-------
shall be in writing and shall be deemed to have been duly given if mailed or
transmitted by any standard form of telecommunication. Notices to the
Underwriters shall be directed to the Representative(s) at North Tower, World
Financial Center, 000 Xxxxx Xxxxxx, Xxx Xxxx, Xxx Xxxx 00000, attention of
Equity Capital Markets, notices to the Company shall be directed to it at 000
Xxx Xxx Xxxx Xxxxx Xxxx, Xxxxxxxxx, Xxx Xxxx 00000-0000, attention of Xxxxxx
Xxxxxxxx, Esq., Vice President, General Counsel and Secretary, and notices to
the Selling Shareholder shall be directed to Amgen Inc., Xxx Xxxxx Xxxxxx Xxxxx,
Xxxxxxxx Xxxx, Xxxxxxxxxx 00000 1789, attention of Corporate Secretary.
SECTION 12. Parties. This Agreement shall inure to the benefit of and
-------
be binding upon the Underwriters, the Company and the Selling Shareholder and
their respective successors. Nothing expressed or mentioned in this Agreement is
intended or shall be construed to give any person, firm or corporation, other
than the Underwriters, the Company and the Selling Shareholder and their
respective successors and the controlling persons and officers and directors
referred to in Sections 6 and 7 and their heirs and legal representatives, any
legal or equitable right, remedy or claim under or in respect of this Agreement
or any provision herein contained. This Agreement and all conditions and
provisions hereof are intended to be for the sole and exclusive benefit of the
Underwriters, the Company and the Selling Shareholder and their respective
successors, and said controlling persons and officers and directors and their
heirs and legal representatives, and for the benefit of no other person, firm or
corporation. No purchaser of Securities from any Underwriter shall be deemed to
be a successor by reason merely of such purchase.
SECTION 13. GOVERNING LAW AND TIME. THIS AGREEMENT SHALL BE GOVERNED
----------------------
BY AND CONSTRUED IN ACCORDANCE WITH THE LAWS OF THE STATE OF NEW YORK. SPECIFIED
TIMES OF DAY REFER TO NEW YORK CITY TIME.
SECTION 14. Effect of Headings. The Article and Section headings
------------------
herein and the Table of Contents are for convenience only and shall not affect
the construction hereof.
26
If the foregoing is in accordance with your understanding of our
agreement, please sign and return to the Company and the Selling Shareholder a
counterpart hereof, whereupon this instrument, along with all counterparts, will
become a binding agreement among the Underwriters, the Company and the Selling
Shareholder in accordance with its terms.
Very truly yours,
REGENERON PHARMACEUTICALS, INC.
By: /s/ Xxxxxxx X. Xxxxxxxxx
___________________________________
Name: Xxxxxxx X. Xxxxxxxxx
Title: President and CEO
AMGEN INC.
By: /s/ Xxxx X. Xxxxxxxxx**
___________________________________
Name: Xxxx X. Xxxxxxxxx
Title: Vice President, Financial
Planning and Analysis
** By delegation of authority from
Xxxxxxx X. Xxxxxxx, Senior Vice
President, Finance and Chief
Financial Officer
CONFIRMED AND ACCEPTED,
as of the date first above written:
XXXXXXX XXXXX & CO.
XXXXXXX LYNCH, PIERCE, XXXXXX & XXXXX
INCORPORATED
X.X. XXXXXX SECURITIES INC.
XXXXXXXXX XXXXXXXX, INC.
By: XXXXXXX LYNCH, PIERCE, XXXXXX & XXXXX
INCORPORATED
By: /s/ Xxxxx X. Xxxxx
_______________________________
Authorized Signatory
For itself and as Representative of the other Underwriters named in Schedule A
hereto.
27
SCHEDULE A
Name of Underwriter Maximum Maximum
-------------------
Number of Number of
Initial Option
Securities Securities
---------- ----------
Xxxxxxx Lynch, Pierce, Xxxxxx & Xxxxx
Incorporated................................... 4,200,000 620,000
X.X. Xxxxxx Securities Inc.......................................... 1,400,000 210,000
Xxxxxxxxx Xxxxxxxx, Inc............................................. 1,400,000 210,000
---------- ----------
Total............................................................... 7,000,000 1,050,000
Sch A-1
SCHEDULE B
List of Sellers
---------------
Name of Seller Maximum Maximum
--------------
Number of Number of
Initial Option
Securities Securities
---------- ----------
Regeneron Pharmaceuticals, Inc. 6,500,000 1,050,000
Amgen Inc. 500,000 0
---------- ----------
Total................................................................... 7,000,000 1,050,000
Sch B-1
SCHEDULE C
REGENERON PHARMACEUTICALS, INC.
7,000,000 Shares of Common Stock
(Par Value $0.001 Per Share)
1. The public offering price per share for the Securities,
determined as provided in said Section 2, shall be $25.00.
2. The purchase price per share for the Securities to be paid by the
several Underwriters shall be $23.75, being an amount equal to the public
offering price set forth above less $1.25 per share; provided that the
purchase price per share for any Option Securities purchased upon the
exercise of the over-allotment option described in Section 2(b) shall be
reduced by an amount per share equal to any dividends or distributions
declared by the Company and payable on the Initial Securities but not
payable on the Option Securities.
Sch C-1
SCHEDULE D
List of persons and entities
subject to lock-up
Xxx Xxxxxxx
Amgen Inc.
Xxxxx X. Xxxxxx
Xxxxxxx X. Xxxxx
Xxxxxxx X. Xxxxx, M.D.
Xxxxx X. Xxxxxxxxx, M.D.
Xxxxxx Xxxxxx Xxxx
Xxxxxxx X. Xxxx
Xxxxx X. Xxxxx
Xxxxxx X. Xxxxxx, M.D., Ph.D.
Xxxxx X. Xxxxx, M.D.
Xxxxxx X. Xxxxxxxx
Xxxxxx X. Xxxxxxxxx, M.D.
Xxxx-Xxxxx Xxxxx, M.D.
Xxxxxxx X. Xxxxx
Xxxxxxx X. Xxxxx
Xxxxxx Xxxxxxxx
Xxxxxxx X. XxXxxxxx
Xxxx X. Xxxxxxxxx
Xxxx Xxxx
The Procter & Xxxxxx Company
Procter & Xxxxxx Pharmaceuticals, Inc.
Xxxxxxx X. Xxxxxxx, M.D.
Xxxxxxx X. Xxxx, Ph.D.
Xxxxxxx X. Xxxxxxxxx, M.D., Ph.D.
Xxxx X. Shooter, Ph.D
Xxxxxx X. Sing
Xxxxxx X. Xxxxxxxxxx, Ph.D.
Xxxx Xxxxx, Ph.D.
Xxxxxxx X. Xxxxxxx
P. Xxx Xxxxxxx, M.D.
Xxxxx X. Xxxxxxxxxx, Ph.D.
Xxxxxx X. Xxxxxxxxxxx, M.D., Ph.D.
Sch D-1
Exhibit A-1
FORM OF OPINION OF GENERAL COUNSEL
TO THE COMPANY TO BE DELIVERED
PURSUANT TO SECTION 5(b)
A-1
Form of Opinion of General Counsel of Regeneron Pharmaceuticals, Inc.
1. The Company has the corporate power and corporate authority to own,
lease and operate its properties and conduct its business in the manner
described in the Prospectus and to enter into and perform its obligations under
the Purchase Agreement.
2. The Company is duly qualified as a foreign corporation to transact
business and is in good standing in each jurisdiction in which the conduct of
its business or its ownership or leasing of property requires such
qualification, except to the extent that the failure to be so qualified would
not have a Material Adverse Effect.
3. Amgen-Regeneron Partners, a Delaware general partnership formed by Amgen
Inc. and the Company ("Amgen-Regeneron Partners"), has been duly formed, is
validly existing as a general partnership under the laws of the State of
Delaware, has the legal power and authority to own its property and to conduct
its business and is in good standing in each jurisdiction in which the conduct
of its business or its ownership or leasing of property requires such
qualification, except to the extent that the failure to be so qualified would
not have a Material Adverse Effect.
4. The Partnership Agreement of Amgen-Regeneron Partners, dated June 21,
1991 (the "Partnership Agreement"), has been duly authorized, executed and
delivered by the Company and is a valid and binding agreement of the Company,
enforceable against the Company in accordance with its terms, except to the
extent that enforcement thereof may be limited by (i) bankruptcy, insolvency,
reorganization, moratorium or other similar laws now or thereafter in effect
relating to creditors' rights generally and (ii) general principles of equity
(regardless of whether enforceability is considered in a proceeding at law or in
equity).
5. The authorized, issued and outstanding capital stock of the Company is
as set forth in the Prospectus in the column entitled "Actual" under the caption
"Capitalization" (except for subsequent issuances, if any, pursuant to the
Purchase Agreement or pursuant to reservations, agreements or employee benefit
plans referred to in the Prospectus or pursuant to the exercise of convertible
securities or options referred to in the Prospectus).
6. The capital stock of the Company outstanding prior to the issuance of
the Company Shares has been duly authorized and is validly issued, fully
paid and non-assessable and free and clear of any preemptive or other similar
rights of any securityholder of the Company arising under applicable law or the
certificate of incorporation or by-laws of the Company or, to my knowledge, any
material agreement or other i nstrument to which the Company is a party.
7. The execution, delivery and performance of the Purchase Agreement and
the consummation of the transactions contemplated in the Purchase Agreement
(including the issuance and sale of the Company Shares and the use of the
proceeds from the sale of the Company Shares as described in the Prospectus
under the caption "Use Of Proceeds") and compliance by the Company with its
obligations under the Purchase Agreement do not and will not, whether with or
without the giving of notice or lapse of time or both, conflict with or
constitute a breach of, or default or Repayment Event (as defined in Section
1(a)(xi) of the Purchase Agreement) under, or result in the creation or
imposition of any lien, charge or encumbrance upon any property or assets of the
Company or, to my knowledge, Amgen-Regeneron Partners pursuant to, any contract,
indenture, mortgage, deed of trust, loan or credit agreement, note, lease or any
other agreement or instrument, known to me, to which the Company or Amgen-
Regeneron Partners is a party or by which it or any of them may be bound, or to
which any of the property or assets of the Company or Amgen-Regeneron Partners
is subject (except for such conflicts, breaches or defaults or liens, charges or
encumbrances that would not have a Material Adverse Effect), nor will such
action result in any violation of the provisions of the charter or by-laws of
the Company or the Partnership Agreement governing Amgen-Regeneron Partners, or
any applicable law, statute, rule, regulation, judgment, order, writ or decree,
known to me, of any government, government instrumentality or court, domestic or
foreign, having jurisdiction over the Company or Amgen-Regeneron Partners or any
of their respective properties, assets or operations.
8. No filing with, or authorization, approval, consent, license, order,
registration, qualification or decree of, any court or governmental authority or
agency, domestic or foreign, (other than under the 1933 Act and 1933 Act
Regulations or as may be required under the securities or blue sky laws of the
various states, as to which I need express no opinion) is necessary or required
by the Company in connection with the due authorization, execution and delivery
of the Purchase Agreement or for the offering, issuance, sale or delivery of the
Company Shares.
9. The Company is not in violation of its charter, by-laws or the
Partnership Agreement and no default by the Company or, to my knowledge, Amgen-
Regeneron Partners exists in the due performance or observance of any
obligation, agreement, covenant or condition contained in any contract,
indenture,
2
mortgage, loan agreement, note, lease or other agreement or instrument that is
described or referred to in the Registration Statement or the Prospectus or
filed or incorporated by reference as an exhibit to the Registration Statement,
except where such default could not reasonably be expected to have a Material
Adverse Effect.
10. The Company has obtained all licenses, permits and other governmental
or regulatory authorizations required for the conduct of its business as
presently conducted and such licenses, permits and authorizations are in full
force and effect and the Company is in all respects complying therewith, except
where the failure to so obtain or comply could not reasonably be expected to
have a Material Adverse Effect.
11. To my knowledge, there is not pending or threatened any action, suit,
proceeding, inquiry or investigation, to which the Company or Amgen-Regeneron
Partners is a party, or to which the property of the Company or Amgen-Regeneron
Partners is subject, before or brought by any court or governmental agency or
body, domestic or foreign, which might reasonably be expected to result in a
Material Adverse Effect or which might be reasonably expected to materially and
adversely affect the properties or assets thereof or the consummation of the
transactions contemplated in the Purchase Agreement or the performance by the
Company of its obligations thereunder.
12. All descriptions in the Registration Statement of contracts and other
documents to which the Company or Amgen-Regeneron Partners is a party are
accurate in all material respects; to my knowledge, there are no franchises,
contracts, indentures, mortgages, loan agreements, notes, leases or other
instruments required to be described or referred to in the Registration
Statement or to be filed as exhibits thereto other than those described or
referred to therein or filed or incorporated by reference as exhibits thereto,
and the descriptions thereof or references thereto are correct in all material
respects.
13. The Rights to purchase Series A Junior Participating Preferred Stock
under the Company's Shareholder Rights Plan to which holders of the Shares
will be entitled have been duly authorized and validly issued.
3
Exhibit A-2
FORM OF OPINION OF COMPANY'S COUNSEL
TO BE DELIVERED PURSUANT TO
SECTION 5(b)
A-2
Form of Opinion of Skadden, Arps, Slate & Xxxx LLP
i. The Company has been duly incorporated and, based
solely upon our review of the New York Certificates,
is a subsisting corporation under the laws of the
State of New York.
ii. The Partnership Agreement of Amgen-Regeneron
Partners, dated June 21, 1991, has been duly authorized,
executed and delivered by the Company and is a valid and
binding agreement of the Company, enforceable against
the Company in accordance with its terms, except to the
extent that enforcement thereof may be limited by (i)
bankruptcy, insolvency, reorganization, moratorium or
other similar laws now or thereafter in effect relating
to creditors' rights generally and (ii) general
principles of equity (regardless of whether
enforceability is considered in a proceeding at law or
in equity).
iii. The Company has the corporate power and corporate
authority to enter into and perform its obligations
under the Purchase Agreement.
iv. The Company Shares have been duly authorized for
issuance and sale to the Underwriters pursuant to the
Purchase Agreement and, when issued and delivered to
and paid for by the Underwriters in accordance with
the Purchase Agreement, will be validly issued, fully
paid and nonassessable. No holder of the Shares is or
will be subject to personal liability by reason of
being such a holder.
v. The issuance of the Company Shares is not subject
to preemptive or other similar rights of any
securityholder of the Company arising under the NYBCL,
under any Applicable Contract or pursuant to the
Company's Certificate of Incorporation or By-Laws.
vi. The Purchase Agreement has been duly authorized,
executed and delivered by the Company.
vii. No Governmental Approval is required in connection
with the due authorization, execution and delivery of
the Purchase Agreement by the Company or for the
issuance and sale by the Company of the Company Shares
to the Underwriters as contemplated by the Purchase
Agreement.
viii. The statements (a) in the Prospectus under the
captions "Description of Capital Stock" and
"Collaborative Relationships", (b) in the Registration
Statement in Item 15, and (c) in the 2000 10-K under the
captions "Collaborative Relationships" and "Legal
Proceedings", in each case insofar as such statements
constitute summaries of certain provisions of the law,
contracts, legal proceedings or documents referred to
therein, fairly summarize the matters referred to
therein in all material respects.
ix. To our knowledge, there are no legal or
governmental proceedings pending or threatened to which
the Company is a party or to which any of the properties
of the Company are subject that are required by the
Rules and Regulations to be described in the
Registration Statement or the Prospectus and are not so
described nor are there any contracts or other documents
that are required by the Rules and Regulations to be
described in the Registration Statement or the
Prospectus or to be filed as exhibits to the
Registration Statement that are not described or filed
as required.
x. The execution, delivery and performance by the
Company of the Purchase Agreement and the consummation
by the Company of the transactions contemplated thereby
(including the issuance and sale of the Company Shares
and the use of the proceeds from the sale of the Company
Shares as described in the Prospectus under the caption
"Use of Proceeds") do not and will not, whether with or
without giving notice or lapse of time or both, (i)
conflict with the Certificate of Incorporation
2
or By-Laws, (ii) constitute a violation or breach of or
default under the terms of any Applicable Contract or
(iii) violate or conflict with, or result in any
contravention of, any Applicable Law, except for such
conflicts, violations or defaults that would not have a
Material Adverse Effect (as defined in the Purchase
Agreement).
xi. The Company is not and upon application of the
proceeds as described under the caption "Use of
Proceeds" in the Prospectus will not be an
"investment company" or an entity "controlled" by an
"investment company," as such terms are defined in
the Investment Company Act of 1940, as amended.
xii. The form of certificate used to evidence the
Common Stock complies in all material respects with the
applicable requirements of each of the NYBCL, the
Charter and By-laws and the Nasdaq National Market.
xiii. The 2000 10-K, when it was filed, appeared on its
face to be appropriately responsive in all material
respects with the requirements of the Exchange Act
and the applicable rules and regulations of the
Commission thereunder, except that we do not express
any opinion as to the financial statements and
related notes and schedules and other financial data
included therein or omitted therefrom or the exhibits
thereto.
xiv. The Registration Statement, at the time it became
effective, and the Prospectus, as of its date, appeared
on their face to be appropriately responsive in all
material respects to the requirements of the Securities
Act and the Rules and Regulations, except that in each
case we do not express any opinion as to the financial
statements and schedules and other financial data
included or incorporated by reference therein or
excluded therefrom, or the exhibits thereto, and, except
to the extent expressly stated in paragraph 8, we do not
assume any responsibility for the accuracy, completeness
or fairness of the statements contained in the
Registration Statement or the Prospectus.
3
Exhibit B
FORM OF OPINION FOR SPECIAL INTELLECTUAL PROPERTY COUNSEL
TO BE DELIVERED PURSUANT TO SECTION 5(b)
B-1
Form of Opinion of Intellectual Property Counsel
of Regeneron Pharmaceuticals, Inc.
1. There are no pending or threatened legal or governmental
proceedings relating to the Company's patents or patent applications which
are required to be disclosed in the Registration Statement and the
Prospectus, other than those discussed therein, and, to my knowledge, all
such pending or threatened legal or governmental proceedings relating to the
Company's patents or patent applications which are not described in the
Registration Statement and the Prospectus, including ordinary routine
litigation incidental to the Company's business, are, considered in the
aggregate, not material; and
2. The statements (a) in the Prospectus under the captions "Risk
Factors-Risks Related to Intellectual Property" and "Business-Patents,
Trademarks, and Trade Secrets," and (b) in the Company's Annual Report on
Form 10-K under the captions "Patents, Trademarks, and Trade Secrets," and
"Legal Proceedings" in each case insofar as such statements constitute
summaries of legal matters, documents or proceedings fairly summarize the
matters referred to therein.
3. Except as described in the Prospectus, there is no pending or
threatened action, suit, proceeding or claim by others that the Company is
infringing any patent which could result in any Material Adverse Effect.
Exhibit C-1
FORM OF OPINION OF COUNSEL TO THE SELLING SHAREHOLDER
TO BE DELIVERED PURSUANT TO
SECTION 5(c)
C-1
Form of Opinion of Xxxxxx & Xxxxxxx
1. No filing with, or consent, approval, authorization, license,
order or registration of, any court or governmental authority or agency, of the
United States or the States of California or New York (other than filings under
the Securities Exchange Act of 1934, the issuance of the order of the Commission
declaring the Registration Statement effective and such authorizations,
approvals or consents as may be necessary under state securities laws, as to
which we express no opinion) is required to be obtained by the Selling
Shareholder for the performance by the Selling Shareholder of its obligations
under the Purchase Agreement, or in connection with the offer, sale or delivery
of the Securities.
2. Upon the crediting of the Securities to the securities account of
the Representative maintained with The Depository Trust Company ("DTC") and
payment therefor by the Underwriters pursuant to the Purchase Agreement, the
Representative will acquire on behalf of the Underwriters a security entitlement
to the Securities and no action based on an adverse claim to the Securities,
whether framed in conversion, replevin, constructive trust, equitable lien or
other theory, may be successfully asserted against the Underwriters under the
Uniform Commercial Code in effect in the State of New York (the "NYUCC"). In
rendering the foregoing opinion, we have assumed that the Underwriters acquired
their interest without notice of an adverse claim.
3. The execution, delivery and performance of the Purchase Agreement
by the Selling Shareholder and the consummation of the transactions contemplated
in the Purchase Agreement will not violate applicable United States, New York or
California law.
Exhibit C-2
FORM OF OPINION OF GENERAL COUNSEL TO THE SELLING
SHAREHOLDER TO BE DELIVERED PURSUANT TO
SECTION 5(c)
C-2
Form of Opinion of the General Counsel of Amgen Inc.
(1) The execution and delivery of the Purchase Agreement has been
duly authorized by all necessary corporate action of Amgen and the Purchase
Agreement has been duly executed and delivered by Amgen.
(2) The execution and delivery by Amgen of, and the sale of the
Securities pursuant to, the Purchase Agreement (A) will not contravene (i) the
Restated Certificate of Incorporation, as amended or the Amended and Restated
Bylaws of Amgen or (ii) any agreement or other instrument identified as an
exhibit to Amgen's annual report on Form 10-K for the fiscal year ended December
31, 2000, and (B) to the best of my knowledge will not contravene any judgment,
order or decree of any governmental body, agency or court having jurisdiction
over Amgen or its business or assets.
[Form of lock-up from directors, officers or other stockholders pursuant to
Section 5(k)]
Exhibit D
., 2001
XXXXXXX XXXXX & CO.
Xxxxxxx Lynch, Pierce, Xxxxxx & Xxxxx Incorporated
X.X. XXXXXX SECURITIES INC.
XXXXXXXXX XXXXXXXX, INC.
as Representative(s) of the several
Underwriters to be named in the
within-mentioned Purchase Agreement
x/x Xxxxxxx Xxxxx & Xx.
Xxxxxxx Lynch, Pierce, Xxxxxx & Xxxxx
Incorporated
Xxxxx Xxxxx
Xxxxx Xxxxxxxxx Xxxxxx
Xxx Xxxx, Xxx Xxxx 00000
Re: Proposed Public Offering by Regeneron Pharmaceuticals, Inc.
Dear Sirs:
The undersigned, a stockholder [and an officer and/or director] of
Regeneron Pharmaceuticals, Inc. a New York corporation (the "Company"),
understands that Xxxxxxx Xxxxx & Co., Xxxxxxx Lynch, Pierce, Xxxxxx & Xxxxx
Incorporated ("Xxxxxxx Xxxxx"), X.X. Xxxxxx Securities Inc., Xxxxxxxxx Xxxxxxxx,
-------------
Inc. and [ ] propose to enter into a Purchase Agreement (the "Purchase
--------
Agreement") with the Company providing for the public offering of shares (the
---------
"Securities") of the Company's common stock, par value $0.001 per share (the
"Common Stock"). In recognition of the benefit that such an offering will confer
------------
upon the undersigned as a stockholder [and an officer and/or director] of the
Company, and for other good and valuable consideration, the receipt and
sufficiency of which are hereby acknowledged, the undersigned agrees with each
underwriter to be named in the Purchase Agreement that, during a period of 90
days from the date of the Purchase Agreement, the undersigned will not, without
the prior written consent of Xxxxxxx Xxxxx, directly or indirectly, (i) offer,
pledge, sell, contract to sell, sell any option or contract to purchase,
purchase any option or contract to sell, grant any option, right or warrant for
the sale of, or otherwise dispose of or transfer any shares of the Company's
Common Stock or any securities convertible into or exchangeable or exercisable
for Common Stock, whether now owned or hereafter acquired by the undersigned or
with respect to which the undersigned has or hereafter acquires the power of
disposition, or file any registration statement under the Securities Act of
1933, as amended, with respect to any of the foregoing or (ii) enter into any
swap or any other agreement or any transaction that transfers, in whole or in
part, directly or indirectly, the economic consequence of ownership of the
Common Stock, whether any such swap or transaction is to be settled by delivery
of Common Stock or other securities, in cash or otherwise.
D-1
Very truly yours,
Signature: ___________________________
Print Name:___________________________
D-2
Exhibit E
Information Provided by Selling Shareholder
The following information was furnished to the Company specifically
for use in the Registration Statement. The name and address and the number of
shares of Common Stock of the Company beneficially owned by the Selling
Shareholder prior to the Offering, which are set forth under the caption
"Selling Shareholder."
E-1
