AGREEMENT

EXHIBIT 1

AGREEMENT

Pursuant to Rule 13d-1(k)(1) under the Securities Exchange Act of 1934, the undersigned hereby agree that only one statement containing the information required by Schedule 13D need to be filed with respect to the ownership by each of the undersigned of shares of Common Stock of Tobira Therapeutics, Inc.

Dated November 3, 2016				Xxxxxxx Healthcare V, L.P.
				By FHM V, L.P., its General Partner
				By FHM V, L.L.C., its General Partner
				By:		/s/ Xxxxx X. Xxxxxx
						Xxxxx X. Xxxxxx, Chief Financial Officer
Dated November 3, 2016				FHM V, L.P.
				By: FHM V, L.L.C., its General Partner
				By:		/s/ Xxxxx X. Xxxxxx
						Xxxxx X. Xxxxxx, Chief Financial Officer
Dated November 3, 2016				FHM V, L.L.C.
				By:		/s/ Xxxxx X. Xxxxxx
						Xxxxx X. Xxxxxx, Chief Financial Officer
Dated November 3, 2016				*
				Xxxx Xxxxxxx
Dated November 3, 2016				*
				Xxxxx Xxxxx
Dated November 3, 2016				*
				Xxxxxxx Xxxxx
Dated November 3, 2016				*
				Xxxxx Xxxxxx
Dated November 3, 2016				*
				Xxxxxx Every
				*By:		/s/ Xxxxx X. Xxxxxx
						Xxxxx X. Xxxxxx, as Attorney-in-Fact

This Schedule 13D was executed by Xxxxx X. Xxxxxx on behalf of the individuals listed above pursuant to a Power of Attorney a copy of which is attached as Exhibit 2.