EXHIBIT 99.1
The shares reported in this Form 3 are held
directly by various subsidiaries of
Credit Suisse, a Swiss bank. Xx.
Xxxxx Xxxxx is a Managing Director of New Leaf
Venture Partners, L.L.C.
(NLV). NLV has entered into an agreement
(the Agreement) with DLJ Capital
Corporation (DLJCC), a Delaware corporation
and indirect subsidiary of
Credit Suisse that directly owns some of the shares
as to which this Form
3 relates. Pursuant to the Agreement, NLV provides
sub-management
services for the Sprout investment portfolio. Xx. Xxxxx may be
deemed to
beneficially own the shares as to which this Form 3 relates. Xx.
Xxxxx
disclaims beneficial ownership of the shares except to the extent of his
pecuniary interest therein.