AGREEMENT ON BIODISTRIBUTION AND INTEGRATION STUDIES OF HIV-PV VACCINE IN MICE
Instructions
The Agreement is a legal-binding document that the Bio-Bridge (Beijing) Science
Corporation (Party A) and the Beijing Institute of Radiation Medicine (Party B)
agree to sign and abide by after mutual consultation. Both of Party A and Party
B may have its legal representative or an agent designated by the representative
sign the Agreement.
Party A: Bio-Bridge (Beijing) Science Corporation
Address: Tianzhu Export Processing Zone, Shunyi District Beijing, China 101312
Legal Representative(pound)-Designated Agent: Xxx Xxx Xxxx/Vice President
Party B: Beijing Institute of Radiation Medicine
Address: 00 Xxxxxxx Xxxx, Xxxxxxx 000000, Xxxxx
Legal Representative(pound)-Designated Agent: Xxxx Xxxxx
On an equal and voluntary basis, Parties A and B have agreed as follows:
ARTICLE [_]
Based on the need of Party A, Party A entrusts Party B to accomplish the
biodistribution and integration in the germ line studies of a anti-HIV vaccine
produced by Party A, HIV-PV.
ARTICLE [_]
Party B agrees to carry out the study program according to the request of Party
A. Party B should begin with the study program after signing of this agreement
and receiving the first part of fund, test and reference sample, and other
necessary data that should be provided by Party A. Party B promise to accomplish
the study within 10 months after the beginning of the program.
ARTICLE [_]
Party A agrees to pay the study fund to Party B by two stages; total amount
should be 200,000 RMB yuan (around USD 24,360). At the first stage, Party A
should pay 80 % of total fund (160,000 RMB yuan, or around USD 19,488) within 7
working days after signing of the agreement. The second part (20 %) of fund
(40,000 RMB yuan, or around USD 4,872) should be paid when Party B submit the
study reports to Party A.
ARTICLE [_]
Party A shall bear the following obligations:
1. To provide Party B with necessary technology data of HIV-PV, including
information of the dosage, administration route, structure and molecular
weight, etc.;
2. To provide Party B with enough amount of test samples with good quality,
labeled with the lot number, concentration, purity, bioactivity and the
unit, storage condition, formulation information;
3. To provide appropriate probes, PCR primers and other necessary sequence
information; 4. To provide Party B with enough amount of relevant assay
reagents; 5. To keep all the technology data provided by Party B secret.
ARTICLE [_]
Party B shall bear the following obligations:
1. To make the study design according to the request of SFDA of China and the
request of Party A; 2. To fulfill the biodistribution and integration profiles
of HIV-PV in mice by using the real-time PCR method; 3. To make out the study
reports according to the regulatory authority issued by SFDA of China. 4. To
keep all the technology data provided by Party A secret.
ARTICLE [_]
Any disputes between the Parties arising under or relating to this Agreement
shall be taken legal proceedings or be arbitrated in accordance with the
Agreement within the boundaries of the People's Republic of China.
ARTICLE [_]
This Agreement consists of 6 original copies, among which Parties A and B keep 3
copies each, Amendments and supplements can be made when the Parties deem it
necessary and agree to do so after consultations.
Legal Representative for Party A or Designated Agent
/s/ Xxx Xxx Xxxx (Signature)
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Legal Representative for Party B or Designated Agent
/s/ Xxxx Xxxxx (Signature)
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Date of Signature 12 (Date) 5 (Month) 2004 (Year)
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