This Amending Agreement is made the 1st day of April, 2005 between NEIL R. CASHMAN ("Cashman"), MARTY LEHTO ("Lehto") (together the "Assignors"), THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO ("University") and AMORFIX LIFE SCIENCES LTD (the...

Exhibit 10.35.1

 This Amending Agreement is made the 1^st day of April, 2005 between

XXXX X. XXXXXXX ("Xxxxxxx"), XXXXX XXXXX ("Xxxxx") (together the "Assignors"), THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO ("University") and AMORFIX LIFE SCIENCES LTD (the "Assignee") (collectively the "Parties").

The Parties entered into an assignment agreement dated the 18^th day of February, 2005 under which the Assignors with the permission of the University assigned and transferred all rights, title and interest in their epitope protection technology to the Assignee (the "Assignment Agreement"); and

As partial consideration for the assignment of rights the Assignee was required to fund further research at the University to develop the invention further under the supervision of Xxxxxxx; and

If Assignee did not enter into a research agreement with the University for at least $200,000.00 in research funding by April 30, 2005 the University or the Assignors could revoke the assignment upon 60 days written notice; and

The imminent departure of Xxxxxxx from the University has made those conditions impossible to achieve and thus the Parties now wish to amend the Assignment Agreement by reference herein; thus

The Parties hereby agree as follows:

1. Except as otherwise defined herein, any capitalized terms used in this Amending Agreement shall have the meanings prescribed by the Assignment Agreement.

2. Article 3.1.2 of the Assignment Agreement is deleted and replaced by the following:

3.1.2 fund further research to be conducted by or under the supervision of Xxxxxxx to develop the Invention further;

3. The milestones in Article 5.3 of the Assignment Agreement are deleted and replaced by the following:

5.3.1 a minimum of $1.2 million gross proceeds in financing to be raised by the Assignee or its successor or affiliate

5.3.2 a minimum of $200,000.00 spent by the Assignee or its successor or assignee on the further research and development of the Invention.

4. The Assignee agrees to indemnify and hold harmless the University and the Assignors for any and all loss or damages suffered by the Assignee with respect to further research and development of the Invention and the Assignee further releases and relieves the University and the Assignors of all liabilities, duties and obligations, incurring as a result of the Assignee's inability to undertake further research and development of the Invention at the University.

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5. All other terms of the Assignment Agreement remain unchanged and in full force and effect.

IN WITNESS WHEREOF the Parties have caused this Agreement to be signed by their duly authorized officers as of the day and date first above written.

SIGNED in the presence of:
/s/ Xxxxx Xxxxxxxx		/s/ Xxxx X. Xxxxxxx
Name of Witness: Xxxxx Xxxxxxxx		XXXX X. XXXXXXX
SIGNED in the presence of:
s/ Xxxxx Xxxxxxxx		/s/ Xxxxx Xxxxx
Name of Witness: Xxxxx Xxxxxxxx		XXXXX XXXXX

THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO			AMORFIX LIFE SCIENCES LTD
By:	/s/ Xxxxx X. Xxxxxxx		By:	/s/ Xxxxxx Xxxxx
				Xxxxxx Xxxxx
	Xxxxx X. Xxxxxxx
	Assistant Vice-President
	Technology Transfer
	University of Toronto

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