EXHIBIT 10.27 MORSE, ZELNICK, ROSE & LANDER A LIMITED LIABILITY PARTNERSHIP

                                                                   EXHIBIT 10.27

                          MORSE, ZELNICK, ROSE & LANDER
                         A LIMITED LIABILITY PARTNERSHIP

                                 000 XXXX XXXXXX
                          XXX XXXX, XXX XXXX 00000-0000
                                  000-000-0000
                               FAX - 000-000-0000

                                                            WRITER'S DIRECT LINE
                                                                  (000) 000-0000


                                 April 15, 2003

Xx. Xxxxxx Xxxxxxx
Milestone Scientific, Inc.
000 Xxxxx Xxxxxx Xxxxxx
Xxxxxxxxxx, Xxx Xxxxxx 00000

Dear Xxx:

      This will confirm that we have agreed to defer payment of an additional
$160,000 in fees due to us until January 2, 2005, except for payments out of
future profits or the net proceeds of equity financings.

      This will further inform that the $160,000 balance of the amount deferred
last year until January 2, 2003 (after giving effect to a $90,000 payment in
restricted shares of Common Stock), is now deferred until January 2, 2005 except
for payments out of future profits or the net proceeds of equity financings,
provided that it does not impact operations.

                                                    Very truly yours,

                                                    /s/ Xxxxxxx X. Xxxxxxx

                                                    Xxxxxxx X. Xxxxxxx

SAZ/ds