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JOINT FILING AGREEMENT
We, the undersigned, hereby express our agreement that the attached
Schedule 13D (including all amendments thereto) is filed on behalf of each of
the undersigned.
BB BIOTECH AG
Date: July 17, 1998 By: /s/ Xxxx-Xxxxx Xxxx
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Name: Xxxx-Xxxxx Xxxx
Signatory Authority
Date: July 17, 1998 By: /s/ Xx. Xxxxxx Xxxxxxxx
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Name: Xx. Xxxxxx Xxxxxxxx
Vice Chairman and Director
BIOTECH FOCUS S.A.
Date: July 17, 1998 By: /s/ Xx. Xxxxxxx Xxxxxx
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Name: Xx. Xxxxxxx Xxxxxx
Signatory Authority
Date: July 17, 1998 By: /s/ Xx. Xxxxxx Xxxxxxx
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Name: Xx. Xxxxxx Xxxxxxx
Signatory Authority
BIOTECH GROWTH S.A.
Date: July 17, 1998 By: /s/ Xx. Xxxxxxx Xxxxxx
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Name: Xx. Xxxxxxx Xxxxxx
Signatory Authority
Date: July 17, 1998 By: /s/ Xx. Xxxxxx Xxxxxxx
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Name: Xx. Xxxxxx Xxxxxxx
Signatory Authority
BIOTECH INVEST S.A.
Date: July 17, 1998 By: /s/ Xx. Xxxxxxx Xxxxxx
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Name: Xx. Xxxxxxx Xxxxxx
Signatory Authority
Date: July 17, 1998 By: /s/ Xx. Xxxxxx Xxxxxxx
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Name: Xx. Xxxxxx Xxxxxxx
Signatory Authority
BIOTECH TARGET S.A.
Date: July 17, 1998 By: /s/ Xx. Xxxxxxx Xxxxxx
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Name: Xx. Xxxxxxx Xxxxxx
Signatory Authority
Date: July 17, 1998 By: /s/ Dr. Xxxxxx Xxxx
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Name: Dr. Xxxxxx Xxxx
Signatory Authority