EXHIBIT 10.22
DURECT CORPORATION
AMENDMENT TO SECOND AMENDED AND RESTATED
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INVESTORS' RIGHTS AGREEMENT
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This Amendment to Second Amended and Restated Investors' Rights Agreement
(the "Agreement") is made as of the 14th day of April, 2000, by and among Durect
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Corporation, a Delaware corporation (the "Company"), and the holders of a
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majority of the Registrable Securities outstanding as of the date hereof (as
such term is defined in the Rights Agreement).
RECITALS
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A. The Company, Xxxxxx X. Xxxxxxx, Xxxxx X. Xxxxx, Xxxxx Xxxxxxxx (the
"Founders"), the holders of the Company's Series A-1 Preferred Stock, the
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holders of the Company's Series A-2 Preferred Stock, the holders of the
Company's Series B Preferred Stock, the holders of the Company's Series B-1
Preferred Stock and the holders of the Company's Series C Preferred Stock
(together the "Preferred Holders") have previously entered into a Second Amended
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and Restated Investor's Rights Agreement dated as of March 28, 2000 (the "Rights
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Agreement"), pursuant to which the Company granted the Founders and the
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Preferred Holders certain rights.
B. The Company and ALZA Corporation ("ALZA") have entered into that
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certain Second Amended and Restated Development and Commercialization Agreement
(the "Development and Commercialization Agreement") effective April 28, 1999,
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pursuant to which the Company has issued to ALZA 1,000,000 shares of the
Company's Common Stock pursuant to a Common Stock Purchase Agreement dated April
14, 2000 (the "Common Stock Purchase Agreement"), and a warrant to purchase
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1,000,000 shares of the Company's Common Stock (the "Warrant"). Pursuant to the
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Development and Commercialization Agreement, the Company has agreed to amend the
Rights Agreement to provide ALZA certain rights to register shares of the
Company's Common Stock issued pursuant to the Common Stock Purchase Agreement or
issued or issuable upon exercise of the Warrant.
C. The Company, the Founders and the Preferred Holders each desire to
amend the Rights Agreement to add the shares of the Company's Common Stock
issuable upon exercise of the Warrant to the definition of Registrable
Securities under the Rights Agreement.
AGREEMENT
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The parties hereby agree as follows:
1. Amendment.
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(a) Section 1.1(b) of the Rights Agreement is hereby amended and
restated to read in its entirety as follows:
"(b) The term "Registrable Securities" means (i) the shares of common
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stock, par value $0.0001 ("Common Stock") (A) issuable or issued upon conversion
of the Series A-1, Series A-2, Series B, Series B-1 and Series C Preferred
Stock, (B) issued to ALZA Corporation pursuant to that certain Common Stock
Purchase Agreement dated April 14, 2000 or (C) issuable or issued upon exercise
of that certain warrant issued to ALZA Corporation dated April 14, 2000, and any
successor Warrant issued upon transfer or exchange thereof, provided, however,
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that for the purposes of Sections 1.2, 1.4, 1.7(a), 1.7(c), 1.13 and 2 the
Series B-1 Preferred Stock shall not be deemed Registrable Securities and the
Series B-1 Holders shall not be deemed Holders (ii) the shares of Common Stock
issued to the Founders (the "Founders' Stock"), provided, however, that for the
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purposes of Sections 1.2, 1.4 and 1.13 the Founders' Stock shall not be deemed
Registrable Securities and the Founders shall not be deemed Holders, and (iii)
any other shares of Common Stock of the Company issued as (or issuable upon the
conversion or exercise of any warrant, right or other security which is issued
as) a dividend or other distribution with respect to, or in exchange for or in
replacement of, the shares listed in (i) and (ii); provided, however, that the
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foregoing definition shall exclude in all cases any Registrable Securities sold
by a person in a transaction in which his or her rights under this Agreement are
not assigned. Notwithstanding the foregoing, Common Stock or other securities
shall only be treated as Registrable Securities if and so long as they have not
been (A) sold to or through a broker or dealer or underwriter in a public
distribution or a public securities transaction, or (B) sold in a transaction
exempt from the registration and prospectus delivery requirements of the
Securities Act under Section 4(1) thereof so that all transfer restrictions, and
restrictive legends with respect thereto, if any, are removed upon the
consummation of such sale;"
2. Except as expressly set forth herein, the Investors' Rights Agreement
shall remain in full force and effect and shall not be modified or altered in
any other way.
3. This Amendment may be executed in two or more counterparts, each of
which shall be deemed an original and all of which together shall constitute one
instrument.
[Signature Page Follows]
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The parties have executed this Amendment to Second Amended and Restated
Investors' Rights Agreement as of the date first above written.
COMPANY:
DURECT CORPORATION
By: /s/ Xxxxx X. Xxxxx
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Xxxxx X. Xxxxx, President
FOUNDERS:
/s/ Xxxxxx X. Xxxxxxx
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Xxxxxx X. Xxxxxxx
/s/ Xxxxx X. Xxxxx
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Xxxxx X. Xxxxx
/s/ Xxxxx Xxxxxxxx
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Xxxxx Xxxxxxxx
INVESTORS:
X.X Xxxxxx/Multi-Market
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By: /s/ Xxxx X. Xxxxxxx
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Title: Vice President
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Print Name: Xxxx X. Xxxxxxx
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Brookside Capital Partners Fund, L.P.
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By: /s/ Xxxx XxXxxxxxx
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Title: Director, Brookside Capital Partners Fund, L.P.
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Print Name: Xxxx XxXxxxxxx
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ALZA Corp.
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By: /s/ Xxxxx Xxxxxx
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Title: Group V.P.
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Print Name: Xxxxx Xxxxxx
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By: /s/ Xxxxx Xxxxxxxx
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Title:
Print Name: Xxxxx Xxxxxxxx
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By: /s/ Xxxxxx X. Xxxxxxx
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Title:
Print Name: Xxxxxx X. Xxxxxxx
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By: /s/ Xxxxx X. Xxxxx
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Title:
Print Name: Xxxxx X. Xxxxx
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Xxxxxxx Capital Group LLC
Agent & Attorney-in-Fact for:
A.Xxxxx Xxxxxxx
The Xxxxxxxx Xxxxxx Foundation
Xxxxx Xxxxxxx Xxxxxx
Xxxxxx X. Xxxxxxx
Trustees of Amherst College
Xxxxxxxx School Endowment Fund
Xxxxxx Xxxxxx Xxxxxxx
Xxxxx X. Xxxxxxx
Xxxxx X. Xxxxxxx
The Xxxx Xxxxxx Foundation
HBL Charitable Unitrust
Xxxxx Xxxx
Xxxxxx X. Xxxxxxx
Psychology Associates
The Xxxxx Foundation
X. Xxxxxxx TTEE E. H. Xxxxxx Xxxxxxx
X. Xxxxxxx TTEE E. H. Xxxxx Xxxxxxx
Xxxxxx Capital, LLC
City of Milford Employee Pension Fund
Xxxxxx Trust Co. of The Bahamas Ltd.
Nat. Fed. of Ind. Bus. Emp. Pen. Tr.
Xxxxxx X. Xxxxxx
Norwalk Employees' Pension Plan
Public Employee Ret. System of Idaho
Roanoke College
City of Stamford Firemen's Pension Fund
State of Oregon/ZCG
Tab Products Company Pension Plan
Xxxxxxx X. Xxxxx
Xxxxx Family LLC
Xxxxxx & Xxxxx Xxxxxxx JTWROS
Xxxxxxx Investment Partners LP
Xxxxxxx X. Xxxxxxxx
Asphalt Green, Inc.
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Xxxxxxxx X. Xxxxxxxxx
Xxxxx X. Xxxxxx
Xxxx X. Xxxxxxxx
Xxxxxxx X. Xxxxx
Xxxxx Xxxx Xxxxxxx
By: /s/ Xxxxxx X. Xxxxxxx
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Title: Principal, Xxxxxxx Capital Group LLC
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Print Name: Xxxxxx X. Xxxxxxx
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