EXHIBIT 10.20
AMENDMENT No. 7
to
THE DEVELOPMENT AND MANUFACTURING
SERVICES AGREEMENT
Dated 08 January 2004
Between
LONZA BIOLOGICS PLC
and
TRUBION PHARMACEUTICALS, INC.
CONFIDENTIAL TREATMENT
THIS AMENDMENT No. 7 ("Seventh Amendment") is made the12th day of May 2005
BETWEEN
LONZA BIOLOGICS PLC of 000 Xxxx Xxxx, Xxxxxx, Xxxxxxxxx XX0 0XX, Xxxxxxx
(hereinafter referred to as "LB"), and
TRUBION PHARMACEUTICALS, INC., of 0000 0xx Xxxxxx, Xxxxx 0000, Xxxxxxx, XX
00000, XXX (herein after referred to as the "Customer")
WHEREAS
A. LB and the Customer entered into a development and manufacturing services
agreement ("the Agreement") dated 08 January 2004, pursuant to which LB
agreed to provide Services to the Customer, and,
B. The Customer now wishes LB to perform additional services under the
Agreement, and,
C. LB is willing to perform such additional services on the terms set out in
the Agreement, and,
D. The parties wish to amend the Agreement in accordance with Clause 13.5
thereto.
NOW THEREFORE IT IS HEREBY AGREED as follows:
1. TWO NEW XXXXXX, XXXXXX 00 XXX 00 XXXXX XX ADDED TO SCHEDULE 2 OF THE
AGREEMENT TO READ AS FOLLOWS:
"STAGE 27 ***
BACKGROUND
***
27.1 OBJECTIVES
***
27.2 ACTIVITIES
***
27.3 DELIVERABLES
27.3.1 A copy of the *** prepared in activity 27.2.1.
27.3.2 Appropriate samples from the *** as agreed in activity 27.2.1.
CONFIDENTIAL TREATMENT
27.3.3 A copy of the *** study report prepared in activity 27.2.12.
27.3.4 Remaining Product (from activity 27.2.16) and/or clarified
culture supernatant (from activity 27.2.15).
27.4 TIMESCALE
Stage 27 can commence upon receipt of the *** at LB and it is
estimated that Stage 27 will be complete approximately *** from the
commencement.
STAGE 28 ***
BACKGROUND
***
28.1 OBJECTIVES
***
28.2 ACTIVITIES
***
28.3 DELIVERABLES
28.3.1 Information package containing the documentation necessary to
***.
28.3.2 Assistance in establishment and qualification ***.
28.4 TIMESCALE
Stage 28 can commence upon signature of this Amendment No. 7 and is
estimated to be complete either *** from commencement or *** after LB's visit to
*** Facility, whichever the sooner.
SCHEDULE 3 TO THE AGREEMENT SHALL BE AMENDED TO INCLUDE PROVISION FOR
PAYMENT FOR THE ABOVE MENTIONED ADDITIONAL SERVICES, AS SET OUT BELOW. INVOICES
FOR THESE ADDITIONAL SERVICES SHALL BE ISSUED, AND CUSTOMER PAYMENTS SHALL BE
MADE, IN ***:
"1. PRICE
***
2. PAYMENT
FOR STAGE 27 - ***
CONFIDENTIAL TREATMENT
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*** upon commencement of ***
*** upon completion of ***
FOR STAGE 27- ***
*** upon commencement ***
*** upon completion ***
FOR STAGE 28 - ***
*** upon commencement of Stage 28.
*** upon completion (no later than 3 months from commencement)
FOR STAGE 28 - ***
*** payable one week following the visit to *** facility
SAVE AS HEREIN PROVIDED ALL OTHER TERMS AND CONDITIONS OF THE AGREEMENT
SHALL REMAIN IN FULL FORCE AND EFFECT.
AS WITNESS the hands of the duly authorised representatives of the parties
hereto the day and year first above written.
Signed for and on behalf of
LONZA BIOLOGICS PLC /s/ Xxxx Imwinkleried
----------------------------------------
Director
TITLE
Signed for and on behalf of
TUBION PHARMACEUTICALS, INC. /s/ Xxxxx X. Xxxxxxxx
----------------------------------------
Chief Executive Officer
TITLE
CONFIDENTIAL TREATMENT
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