AMENDMENT ONE To LIMITED EXCLUSIVE LICENSE AGREEMENT FOR OPTICAL COHERENCE TOMOGRAPHY For Human and Animal Dentistry Between THE REGENTS OF THE UNIVERSITY OF CALIFORNIA AND LANTIS LASER, INC. LLNL Case No. TL-1640-00 Lawrence Livermore National...

AMENDMENT ONE

To

LIMITED EXCLUSIVE LICENSE AGREEMENT

FOR

OPTICAL COHERENCE TOMOGRAPHY

For Human and Animal Dentistry

Between

THE REGENTS OF THE UNIVERSITY OF CALIFORNIA

AND

XXXXXX LASER, INC.

LLNL Case No. TL-1640-00

Xxxxxxxx Livermore National Laboratory

University of California

X.X. Xxx 000, X-000, Xxxxxxxxx, XX 00000

Individual Partnerships and Commercialization

September 24, 2004

AMENDMENT ONE

September 2004

To

License Agreement - LLNL Case Number TL-1640-00

For Optical Coherence Tomography for Human and Animal Dentistry

between Xxxxxx Laser, Inc., and

The Regents of the University of California

effective September 14, 2001

This Amendment One to the License Agreement by and between The Regents of the University of California (“THE REGENTS”) and Xxxxxx Laser, Inc. (“LICENSEE”) will be effective as of the date of execution of this Amendment by both Parties. This Amendment and the associated License Agreement are subject to overriding obligations to the Federal Government pursuant to the provisions of THE REGENTS’ Contract No. W-7405-ENG-48 with the United States Department of Energy (“DOE”) for the operation of the Xxxxxxxx Livermore National Laboratory (“LLNL”).

This Amendment One will remove U.S. Patent Application No. 09/489,764, which has been abandoned, from the Licensed Patents. It has been determined that there is not enough scope in light of prior art to continue prosecution of this case. Exhibit A (LICENSED PATENTS) has been updated to reflect this change and the current status of the licensed patents. All other terms and conditions remain the same.

Therefore, in consideration of the mutual covenants and obligations recited herein, THE REGENTS and LICENSEE hereby amend the License Agreement as follows:

1. EXHIBIT A (LICENSED PATENTS)

Delete Exhibit A in its entirety and replace with the following:

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EXHIBIT A - LICENSED PATENTS

The Licensed Patents are as follows:

UNITED STATES PATENTS:

Invention Disclosure Number		Patent Number		Title		Inventors		Filing Date		Issue Date
IL-9247		5,570,182		Method for Detection of Dental Caries and Periodontal Disease Using Optical Imaging		Xxxxxx Xxxxxx, Xxxx X. Xxxxxx, Xxxxx X. Xxxx		5/27/94		10/29/96
IL-10371		6,179,611		Dental Optical Coherence Domain Reflectometry Explorer		Xxxxxxx X. Xxxxxxx, Xxxxx X. Xxxxxxx Xx., Xxxxx X. Sathyam, Xxxx X. Xx Xxxxx		5/19/99		1/22/01
IL-10379		6,385,358		Birefingence Insensitive Optical Coherence Domain Reflectometry System		Xxxxxxx X. Xxxxxxx, (LLNL), Xxxxxx Xxxx Xxxxx (OptiPhase, Inc.)		1/7/00		5/7/02
IL-10408B		6,522,407		Optical Detection of Dental Disease Using Polarized Light		Xxxxxxx X. Xxxxxxx, Xxxxx X. Xxxxxxx, Xx., Xxxxx X. Sathyam, Xxxx X. Xx Xxxxx, Xxxxxx Xxxxx		3/18/03		2/18/03
IL-10616		6,466,713		Optical Fiber Head for Providing Lateral Viewing		Xxxx X. Xx Xxxxx, Xxxxx X. Xxxxxxx Xx., Xxxx X. Xxxxx		9/12/00		7/16/02
IL-10697		6,451,009		OCDR Guided Laser Ablation Device		Xxxx X. Xx Xxxxx, Xxxxx X. Xxxxxxx Xx., Xxxx X. Xxxxx		9/12/00		9/17/02

FOREIGN PATENT APPLICATIONS:

None.

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THE REGENTS and LICENSEE execute this Agreement, in duplicate originals, by their respective officers who are duly authorized on the day and year that is written.

XXXXXX LASER, INC.		THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
		XXXXXXXX LIVERMORE NATIONAL LABORATORY
By:		By:
		(Signature)
Name:		Name:
Title:		Title:
Date Signed: ______________________		Date Signed: ____________________, 2004

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