Attachment: Compliance Confirmation Letter To whom it might concern:

Exhibit 4.100

Attachment: Compliance Confirmation Letter

To whom it might concern:

From: DVB Bank SE (acting as Agent on behalf of the Lenders)

Date: 25^th of November 2010

Re: Compliance Confirmation Letter

We herewith in our capacity as Lenders in Loan Agreement dated 10 September 2007, as amended by a First Supplemental Agreement dated 10 January 2008 and as further amended by a Second Supplemental Agreement dated 23 January 2009, made between (1) Drillship Hydra Owners Inc. and Drillship Paros Owners Inc. as joint and several borrowers, (2) the banks listed in schedule 1 thereto as lenders, (3) the banks listed in schedule 1 thereto as arrangers and (4) DVB Bank SE (formerly known as DVB Bank AG (“DVB”) as agent, underwriter and security agent, in respect of a loan facility of up to US$230,000,000, (the “Loan Agreement”), herewith confirm that Dryships Inc. (and defined Borrowing entities) are in full compliance with the Loan Agreement (as supplemented / addended from time during the duration of the loan).

This Compliance Confirmation is valid until December 31^st 2010.

Signed:

/s/ Sjur Agdestein				/s/ Xxxxxx Xxxxxxxx
Sjur Agdestein				Xxxxxx Xxxxxxxx
Managing Director				Vice President

DVB Bank SE Nordic Branch
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