Confidential material omitted and filed separately with the Securities and
Exchange Commission. Asterisks denote such omissions.
Exhibit 10.30
LICENSE, TECHNOLOGY TRANSFER AND TECHNOLOGY SERVICES AGREEMENT
This License, Technology Transfer and Technology Services Agreement
("Agreement") is entered into as of February 2, 2000 (the "Effective Date"), by
and between Dyax Corp., a Delaware corporation with principal offices located at
Xxx Xxxxxxx Xxxxxx, Xxxxxxxx 000, Xxxxx 000, Xxxxxxxxx, Xxxxxxxxxxxxx 00000
(together with its Affiliates (as defined below), "Dyax"), and Amgen Inc., a
Delaware corporation, Xxx Xxxxx Xxxxxx Xxxxx, Xxxxxxxx Xxxx, Xxxxxxxxxx
00000-0000 (together with its Affiliates, "Amgen").
WITNESSETH:
WHEREAS, Dyax possesses intellectual property and Know-How (as defined
herein) related to the discovery of proteins, peptides and antibodies having
novel binding properties using phage display, including certain Licensed Patents
(as defined herein);
WHEREAS, Amgen is engaged in the research, development and
commercialization of human pharmaceutical products;
WHEREAS, Amgen wishes for Dyax to transfer and license to Amgen the right
to use certain Original Material (as defined herein) under the terms and
conditions hereof;
WHEREAS, Amgen wishes for Dyax to use its proprietary technology to
construct New Material (as defined herein) which Dyax will license to Amgen for
use under the terms and conditions hereof;
WHEREAS, Amgen desires to obtain licenses from Dyax to use the Licensed
Dyax Material and the Know-How, and to practice the inventions described in the
Licensed Patents in the Field of Use (each as defined herein), and Dyax is
willing to grant such licenses under the terms and conditions hereof.
NOW, THEREFORE, in consideration of the foregoing and the covenants and
premises contained in this Agreement, the parties hereto hereby agree as
follows:
1. DEFINITIONS
1.1 "Affiliate" means a Person that, directly or indirectly, through one
or more intermediaries, controls, is controlled by, or is under common control
with the Person specified. For the purposes of this definition, "control" shall
mean the possession, direct or indirect, of the power to cause the direction of
the management and policies of a Person, whether through ownership of more than
fifty percent (50%) of the voting securities of such Person, by contract or
otherwise.
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Confidential material omitted and filed separately with the Securities and
Exchange Commission. Asterisks denote such omissions.
1.2 *************
1.3 "Amgen Property" shall have the meaning set forth in Section 3.4.
1.4 "BLA" means a Biological License Application as defined in the U.S.
Food, Drug and Cosmetic Act and the regulations promulgated thereunder, as
amended, and any filing under any successor laws and regulations.
1.5 "Code" shall have the meaning set forth in Section 9.4(b).
1.6 "Commercially Reasonable Efforts" means *************.
1.7 "Completed New Material" shall have the meaning set forth in Section
4.2.
1.8 "Confidential Information" shall mean all confidential and/or
proprietary information, materials, Know-How, software and other data, both
technical and nontechnical of a party which is disclosed by such party at any
time during the term of this Agreement pursuant to or in furtherance of this
Agreement, except that which the party receiving such Confidential Information
can establish by competent evidence:
(a) is or later becomes generally available to the public by use,
publication or the like, through no fault of the receiving party, its
officers, directors, agents or employees; or
(b) is obtained from a third party without restriction who had legal right
to disclose the same to the receiving party; or
(c) the receiving party already possessed and obtained from a source other
than the disclosing party prior to receipt thereof from the disclosing
party; or
(d) is independently developed by the receiving party without the use of
Confidential Information belonging to the disclosing party as evidenced by
the receiving party's written records.
1.9 "Controls" or "Controlled" means possession of the ability to grant
licenses or sublicenses without violating the terms of any agreement or other
arrangement with, or the rights of, any Third Party.
1.10 "Default" means a Performance Default or a Representation Default.
1.11 "Defaulting Party" shall have the meaning set forth in Section
9.3(a).
1.12 "Field of Use" means all human therapeutic and prophylactic uses
*************. The Field of Use shall not include *************.
1.13 *************
1.14 "Improvement" means any improvement to any Original Material or New
Material *************.
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Confidential material omitted and filed separately with the Securities and
Exchange Commission. Asterisks denote such omissions.
1.15 "IND" means an Investigational New Drug application as defined in the
U.S. Food, Drug and Cosmetic Act and the regulations thereunder, as amended, and
any filing under any successor laws and regulations.
1.16 "Insolvent Party" shall have the meaning set forth in Section 9.4(a).
1.17 "Interim New Material" shall have the meaning set forth in Section
4.2.
1.18 "Know-How" means all information actually disclosed by Dyax to Amgen,
whether or not patentable, constituting materials, methods, processes,
techniques, information and data relating to the Licensed Dyax Material, which
information Dyax treats as proprietary to Dyax and which information is
disclosed to Amgen in a clear writing as proprietary to Dyax.
1.19 "Licensed Dyax Material" means the Original Material, the New
Material, and any Improvements, but shall not include the Amgen Property.
1.20 *************
1.21 "Licensed Patents" means any and all patent applications, and all
continuations, continuations-in-part, patents-of-addition and divisionals of
such patent applications, and any patents that may issue based upon such patent
applications, together with any Supplementary Protection Certificates or the
equivalent thereof, reissues, reexaminations, renewals, certificates of
invention, substitutions, confirmations, re-registrations, revalidations,
restorations and extensions thereof, and all counterparts thereto in countries
outside of the United States, all of which as of the Effective Date are listed
in Exhibit A; provided, however, that "Licensed Patents" shall not include
*************. Dyax shall keep Amgen currently informed in writing of any
additions and amendments to Exhibit A.
1.22 "Licensed Product" means any product in the Field of Use discovered,
made or developed by Amgen *************.
1.23 "Licensed Territory" means worldwide.
1.24 "Milestone Event" shall have the meaning set forth in Section 6.1(b).
1.25 "Milestone Payment" shall have the meaning set forth in Section
6.1(b).
1.26 "NDA" means a New Drug Application as defined in the U.S. Food, Drug
and Cosmetic Act and the regulations thereunder, as amended.
1.27 "New Material" means the phage display library and related reagents
and protocols ************* as set forth in Exhibit B. New Material shall
include the Interim New Material and the Completed New Material.
1.28 "Non-Defaulting Party" shall have the meaning set forth in Section
9.3(a).
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Confidential material omitted and filed separately with the Securities and
Exchange Commission. Asterisks denote such omissions.
1.29 "Notice of Default" shall have the meaning set forth in Section
9.3(a).
1.30 "Original Material" means Dyax's proprietary ************* phage
display libraries and related reagents and protocols set forth in Exhibit C.
1.31 "Patent License Effective Date" means February 12, 1999.
1.32 "Patent Rights" means patent applications, patents issuing thereon
and any extensions or restorations by existing or future extension or
restoration mechanisms, including without limitation Supplementary Protection
Certificates or the equivalent thereof, renewals, continuations,
continuations-in-part, divisionals, patents-of-addition, certificates of
invention, extensions, substitutions, confirmations, re-registrations,
re-examinations, revalidations and/or reissues of any patent, and any foreign
counterparts thereof.
1.33 "Performance Default" shall have the meaning set forth in Section
9.3(a).
1.34 "Person" means an individual, a partnership, a joint venture, a
corporation, a limited liability company, a trust, an estate, an unincorporated
organization, or any other entity, or a government or any department or agency
thereof.
1.35 "Representation Default" shall have the meaning set forth in Section
9.3(a).
1.36 "Term" means the term of this Agreement, as set forth in Section 9.1.
1.37 "Third Party" means any Person that is not an Affiliate of Amgen or
Dyax.
2. REPRESENTATIONS AND WARRANTIES
2.1 Representations and Warranties of Dyax.
(a) Corporate Power. Dyax is a corporation duly organized, validly
existing and in good standing under the laws of the State of Delaware, and has
full corporate power and authority to enter into this Agreement and to carry out
the provisions hereof.
(b) Due Authorization. The execution, delivery and performance of this
Agreement have been duly authorized by all necessary corporate action on the
part of Dyax, and the person executing this Agreement on behalf of Dyax has been
duly authorized to do so by all requisite corporate action.
(c) Binding Agreement; No Conflict. This Agreement is and shall be a legal
and valid obligation binding upon Dyax, enforceable in accordance with its
terms. The execution, delivery and performance of this Agreement by Dyax, and
the granting of the licenses to Amgen hereunder, do not conflict with any
agreement, instrument or understanding, oral or written, to which it is a party
or by which it may be bound, nor violate any material law or regulation of any
court, governmental body or administrative
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Confidential material omitted and filed separately with the Securities and
Exchange Commission. Asterisks denote such omissions.
or other agency having jurisdiction over it.
(d) Grant of Rights. Dyax has not, and will not during the Term, grant any
right to any Third Party which would conflict with the rights granted to Amgen
and its Affiliates hereunder.
(e) Validity. Dyax is aware of no action, suit or inquiry or investigation
instituted by any United States federal or state governmental agency which
questions or threatens the validity of this Agreement or the Licensed Patents.
(f) Licensed Patents. Subject to non-exclusive licenses granted to Third
Parties, Dyax possesses the exclusive right, title and interest in and to the
Licensed Patents in the Field of Use in the Licensed Territory, all of which are
as of the Patent License Effective Date and as of the Effective Date
unencumbered by any lien, security interest, or other right or claim of any
Third Party. The Licensed Patents include all Patent Rights owned or Controlled
by Dyax as of the Patent License Effective Date and as of the Effective Date
*************.
(g) Licensed Dyax Material and Know-How. Subject to non-exclusive licenses
granted to Third Parties, Dyax exclusively owns the Licensed Dyax Material and
the Know-How in the Field of Use, all of which are as of the Effective Date
unencumbered by any lien, security interest, or other right or claim of any
Third Party. *************.
2.2 Representations and Warranties of Amgen.
(a) Corporate Power. Amgen is a corporation duly organized, validly
existing and in good standing under the laws of the State of Delaware, and has
full corporate power and authority to enter into this Agreement and to carry out
the provisions hereof.
(b) Due Authorization. The execution, delivery and performance of this
Agreement have been duly authorized by all necessary corporate action on the
part of Amgen, and the person executing this Agreement on behalf of Amgen has
been duly authorized to do so by all requisite corporate action.
(c) Binding Agreement. This Agreement is and shall be a legal and valid
obligation binding upon Amgen, enforceable in accordance with its terms. The
execution, delivery and performance of this Agreement by Amgen does not conflict
with any agreement or instrument to which it is a party or by which it may be
bound, nor violate any material law or regulation of any court, governmental
body or administrative or other agency having jurisdiction over it.
3. GRANT OF LICENSE; AMGEN PROPERTY
3.1 Patent License Grant. Subject to the terms and limitations of this
Agreement, Dyax hereby grants to Amgen as of the Patent License Effective Date a
non-exclusive license in the Licensed Territory under the Licensed Patents to
make, develop
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Confidential material omitted and filed separately with the Securities and
Exchange Commission. Asterisks denote such omissions.
and use ************* in the Field of Use and to make, have made, use, sell,
offer for sale and import Licensed Products in the Field of Use, *************
no provision of this Agreement shall be deemed to restrict Amgen's ability to
license, sublicense, assign or otherwise transfer any or all of its rights in or
to any Licensed Product or any other Amgen Property.
3.2 Technology License Grant. Dyax hereby grants to Amgen a non-exclusive
license in the Licensed Territory to the Licensed Dyax Material and the Know-How
to make, develop and use ************* in the Field of Use and to make, have
made, use, sell, offer for sale and import Licensed Products in the Field of
Use, ************* no provision of this Agreement shall be deemed to restrict
Amgen's ability to license, sublicense, assign or otherwise transfer any or all
of its rights in or to any Licensed Product or any other Amgen Property.
3.3 Ownership of Licensed Dyax Material; Reservation of Rights. Dyax is
and shall remain the owner of all Licensed Dyax Material and the Know-How,
subject to the rights granted to Amgen set forth in this Agreement. All rights
to the Licensed Patents, the Licensed Dyax Material and the Know-How not
expressly granted under this Agreement, as well as to any other Dyax proprietary
phage display library and to Dyax Patent Rights other than the Licensed Patents,
are reserved to Dyax, including the right to grant the same rights to any Third
Party as Dyax has granted to Amgen hereunder. *************.
3.4 Amgen Property. Amgen shall solely and exclusively own all Licensed
Products, ************* other pharmaceutical or therapeutic products or
candidates made, discovered, derived or developed by Amgen in connection with or
resulting from Amgen's use of the Licensed Dyax Material or the Know-How or
Amgen's use of any method or composition of matter, the use of which would, but
for the licenses granted hereunder, infringe one or more claims of the Licensed
Patents, including but not limited to, *************, all of which shall be
owned exclusively by Amgen without restriction (collectively, the "Amgen
Property"), and Dyax, its officers, directors, employees, agents and consultants
shall have no rights, claims or interests whatsoever (including but not limited
to Amgen's Patent Rights and any other intellectual property rights) in or to
the Amgen Property, *************.
3.5 *************
4. DYAX DELIVERABLES
4.1 Original Material. Within ************* of the Effective Date, Dyax
shall deliver to Amgen the Original Material set forth on Exhibit C.
4.2 New Material. Dyax shall construct the New Material in accordance with
the specifications set forth in Exhibit B and the timeline set forth in this
Section 4.2. Dyax agrees to devote Commercially Reasonable Efforts to complete
construction of the New Material in accordance with the foregoing specifications
and timeline. During the course of the work, Dyax representatives shall consult
with Amgen representatives upon the request of Amgen in order to facilitate the
exchange of
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Confidential material omitted and filed separately with the Securities and
Exchange Commission. Asterisks denote such omissions.
information relating to the work being performed by Dyax. Dyax shall deliver to
Amgen ************* as set forth in Exhibit B, *************. Dyax shall deliver
to Amgen the completed New Material (collectively, the "Completed New Material")
as set forth in Exhibit B, *************. The work being performed by Dyax shall
be deemed complete *************.
4.3 Related Technology and Technology Services. During the Term, Dyax
shall provide the following to Amgen:
(a) ************* on such dates as may be mutually determined by Dyax and
Amgen, at a cost of *************, plus all reasonable travel and reasonable
out-of-pocket expenses of such scientist; and
(b) In addition to the services described in Section 4.3(a), telephone and
remote technical support required by Amgen in its use of the Licensed Dyax
Material ************* set forth in Section 4.1, as requested from time to time
by Amgen, at a cost of *************; and
(c) Such additional training and telephone and remote technical support
with respect to the New Material as the parties may subsequently agree in
writing, at a cost of *************; and
(d) *************.
5. DEVELOPMENT AND COMMERCIALIZATION
5.1 Development. Amgen, in its sole discretion, will make all decisions
relating to the development of Licensed Products including, but not limited to,
all decisions relating to the research, pre-clinical development and clinical
development of Licensed Products.
5.2 Commercialization. Amgen, in its sole discretion, will make all
decisions relating to the commercialization of Licensed Products including, but
not limited to, all decisions relating to the promotion, advertising, marketing
and pricing of Licensed Products.
6. AMGEN PAYMENTS
6.1 Patent License Payments. In consideration of the license under the
Licensed Patents granted by Dyax to Amgen pursuant to Section 3.1:
(a) Within ************* after the Effective Date, Amgen shall pay to Dyax
a ************* license fee *************; and
(b) Within ************* days after the occurrence of each of the
following events (each, a "Milestone Event") with respect to a Licensed Product
*************, Amgen will make the following milestone payments (each, a
"Milestone Payment") to Dyax:
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Confidential material omitted and filed separately with the Securities and
Exchange Commission. Asterisks denote such omissions.
Milestone Event Milestone Payment
--------------- -----------------
************* *************
************* *************
************* *************
Notwithstanding the foregoing, a Milestone Payment shall only be due and
payable *************.
(c) Amgen shall not be obligated to make any Milestone Payment under
Section 6.1(b) more than once with respect to any Licensed Product, and upon the
making of all Milestone Payments with respect to any Licensed Product Amgen
shall have a fully paid-up, unrestricted license under the Licensed Patents to
make, have made, use, sell, offer to sell and import such Licensed Product in
the Field of Use in the Licensed Territory, *************. No provision of this
Agreement shall be deemed to restrict Amgen's ability to license, sublicense,
assign or otherwise transfer any or all of its rights in or to any Licensed
Product or any other Amgen Property.
(d) Amgen shall not be obligated to make any Milestone Payment under
Section 6.1(b) *************, Amgen shall have a fully paid-up, unrestricted
license under the Licensed Patents to make, have made, use, sell, offer to sell
and import all Licensed Products in the Field of Use in the Licensed Territory,
*************. No provision of this Agreement shall be deemed to restrict
Amgen's ability to license, sublicense, assign or otherwise transfer any or all
of its rights in or to any Licensed Product or any other Amgen Property.
6.2 Technology Payments. In consideration of the license pursuant to
Section 3.2 with respect to the Original Material, and the deliverables provided
to Amgen pursuant to Section 4.1, Amgen shall pay Dyax the sum *************
following the date Amgen receives from Dyax the Original Material as provided in
Section 4.1. In consideration of the license pursuant to Section 3.2 with
respect to the New Material, and the deliverables provided to Amgen pursuant to
Section 4.2, Amgen shall pay Dyax the sum *************.
6.3 Payments in United States Dollars; No Additional Consideration. All
payments due under this Agreement shall be made in United States dollars. The
parties hereby agree that the payments set forth in Sections 6.1 and 6.2
constitute all payments due and payable under this Agreement, and that no
additional consideration shall be payable by Amgen under this Agreement.
7. CONFIDENTIALITY
7.1 Non-Disclosure of Confidential Information. Except to the extent
expressly authorized by this Agreement, neither party shall (i) disclose,
publish or make available any Confidential Information disclosed to it by the
other to any Third Party,
8
nor to any employees who do not need to know or have access to such Confidential
Information or (ii) transfer or otherwise use or exploit any such Confidential
Information.
8. INDEMNIFICATION
8.1 Indemnification by Amgen. Amgen shall indemnify and hold Dyax, its
officers, directors, employees and agents harmless from all liability, loss,
damage and cost arising out of (a) any claim, demand, suit or other action of
any nature brought by any Third Party (other than claims by any Third Party
relating to infringement of Third Party Patent Rights as provided in Section
2.1(g)) arising out of the using of the Licensed Dyax Material or the Know-How
or the making, having made, using, selling, offering to sell or importing of
Licensed Products by, on behalf of, or under authority of, Amgen or (b) any
representation or warranty by Amgen set forth herein being untrue in any
material respect when made or material breach or material default by Amgen of
any of its obligations hereunder. Dyax will notify Amgen in the event it becomes
aware of a claim for which indemnification may be sought hereunder.
Notwithstanding the foregoing, no Person shall be entitled to indemnification
under this Section 8.1 against any liability, damage, cost (including reasonable
attorneys' fees) or expense arising out of Dyax's negligence, recklessness or
willful misconduct.
8.2 Indemnification by Dyax. Dyax shall indemnify and hold Amgen, its
officers, directors, employees and agents harmless from all liability, loss,
damage and cost arising out of (a) any claim, demand, suit or other action of
any nature brought by any Third Party arising out of the making, having made,
using, selling, offering to sell, licensing, offering to license or importing of
the Licensed Dyax Material or the Know-How or the practice of the claimed
subject matter of the Licensed Patents by, on behalf of, or under authority of,
Dyax or any Third Party licensee of Dyax or (b) any representation or warranty
by Dyax set forth herein being untrue in any material respect when made or
material breach or material default by Dyax of any of its obligations hereunder.
Amgen will notify Dyax in the event it becomes aware of a claim for which
indemnification may be sought hereunder. Notwithstanding the foregoing, no
Person shall be entitled to indemnification under this Section 8.2 against any
liability, damage, cost (including reasonable attorneys' fees) or expense
arising out of Amgen's negligence, recklessness or willful misconduct.
8.3 Dyax Disclaimer of Warranties. Nothing in this Agreement shall be
construed as a warranty or representation by Dyax that Amgen's use of the
Licensed Patents, the Licensed Dyax Material or the Know-How will result in the
discovery of any Licensed Intermediate or any Licensed Product. EXCEPT AS SET
FORTH IN SECTION 2.1 HEREOF, DYAX DISCLAIMS ANY AND ALL WARRANTIES OF ANY KIND
WITH RESPECT TO THE LICENSED PATENTS, THE LICENSED DYAX MATERIAL AND THE
KNOW-HOW, WHETHER EXPRESS OR IMPLIED, INCLUDING, BUT NOT LIMITED TO, ANY
WARRANTIES OF MERCHANTABILITY OR FITNESS FOR A PARTICULAR PURPOSE OR THE
WARRANTY OF NONINFRINGEMENT.
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Confidential material omitted and filed separately with the Securities and
Exchange Commission. Asterisks denote such omissions.
9. TERM; TERMINATION
9.1 Term. Subject to the provisions of Section 9.5, the Term shall
commence as of the Effective Date and, unless terminated earlier pursuant to
this Section 9, shall terminate upon the expiration of the last to expire of the
Licensed Patents. Upon the expiration of the Term, Amgen shall have an
unrestricted license to make, have made, use, sell, offer to sell and import all
Licensed Products in the Field of Use in the Licensed Territory, subject to any
outstanding payment obligations in accordance with Section 6.1. Notwithstanding
the foregoing, this Agreement may be earlier terminated pursuant to Section 9.2.
9.2 Termination of Agreement for Convenience. At any time during the Term,
Amgen may, upon ************* notice to Dyax, terminate this Agreement, subject
to the provisions of Section 9.5.
9.3 Default.
(a) In the event any representation or warranty made hereunder by either
party shall have been untrue in any material respect ("Representation Default")
or upon any material breach or material default of an obligation of this
Agreement by a party ("Performance Default"), the party not in default
("Non-Defaulting Party") must first give the other party ("Defaulting Party")
written notice thereof ("Notice of Default"), which notice must state the nature
of the Representation Default or Performance Default in reasonable detail and
request the Defaulting Party cure such default within thirty (30) days. If the
Defaulting Party shall dispute the existence, extent or nature of any default
set forth in a Notice of Default, the parties shall use good faith efforts to
resolve the dispute.
(b) In the event of (i) a Representation Default by Dyax wherein the
underlying facts shall not have been brought into conformity with the
representation and warranty within the period set forth in Section 9.3(a) after
receipt of a Notice of Default (or, if the underlying facts of such
Representation Default cannot be brought into conformity within such period and,
in the determination of Amgen, Dyax shall have failed to commence substantial
remedial actions to bring such facts into conformity within such period and to
diligently pursue the same) or (ii) a Performance Default by Dyax that shall not
have been cured within the period set forth in Section 9.3(a) after receipt of a
Notice of Default (or, if such Performance Default cannot be cured within such
period and, in the determination of Amgen, Dyax shall have failed to commence
substantial remedial actions to cure such Performance Default within such period
and to diligently pursue the same), then upon such failure of Dyax to cure such
Representation Default or Performance Default, Amgen (in addition to any other
remedies which may be available to Amgen at law or equity), at its option, may
terminate this Agreement. Upon such termination by Amgen, Amgen shall have an
unrestricted license to make,
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Confidential material omitted and filed separately with the Securities and
Exchange Commission. Asterisks denote such omissions.
have made, use, sell, offer to sell and import all Licensed Products in the
Field of Use in the Licensed Territory *************.
(c) In the event of a Performance Default by Amgen that shall not have
been cured within the period set forth in Section 9.3(a) after receipt of a
Notice of Default (or, if such Performance Default cannot be cured within such
period and, in the determination of Dyax, Amgen shall have failed to commence
substantial remedial actions to cure such Performance Default within such period
and to diligently pursue the same), Dyax (in addition to any other remedies
which may be available to Dyax at law or equity), at its option, may terminate
this Agreement, subject to the provisions of Section 9.5.
9.4 Insolvency or Bankruptcy.
(a) In addition to any other remedies available to it by law or in equity,
either party may terminate this Agreement upon providing written notice to the
other party (the "Insolvent Party"), in the event the Insolvent Party shall have
become insolvent or bankrupt or shall have made an assignment for the benefit of
its creditors, or there shall have been appointed a trustee or receiver of the
Insolvent Party, or for all or a substantial part of its property, or any case
or proceeding shall have been commenced or other action taken by or against the
Insolvent Party in bankruptcy or seeking reorganization, liquidation,
dissolution, winding-up arrangement, composition or readjustment of its debts or
any other relief under any bankruptcy, insolvency, reorganization or other
similar act or law of any jurisdiction now or hereafter in effect, or there
shall have been issued a warrant of attachment, execution, distraint or similar
process against any substantial part of the property of the Insolvent Party, and
any such event shall have continued for forty-five (45) days undismissed,
unbonded and undischarged.
(b) All rights and licenses granted under or pursuant to this Agreement by
Amgen or Dyax are, and shall otherwise be deemed to be, for purposes of Section
365(n) of the U.S. Bankruptcy Code (the "Code"), licenses of rights to
"intellectual property" as defined under Section 101 of the Code. The parties
agree that each party which shall be a licensee of such rights under this
Agreement shall retain and may fully exercise all of its rights and elections
under the Code. The parties further agree that, in the event of the commencement
of a bankruptcy proceeding by or against either party under the Code, the party
hereto which shall not be a party to such proceeding shall be entitled to a
complete duplicate of (or complete access to, as appropriate) any such
intellectual property and all embodiments of such intellectual property, and
same, if not already in their possession, shall be promptly delivered to them
(i) upon any such commencement of a bankruptcy proceeding upon their written
request therefor, unless the party subject to such proceeding (or a trustee on
behalf of the subject party) elects to continue to perform all of their
obligations under this Agreement or (ii) if not delivered under (i) above, upon
the rejection of this Agreement by or on behalf of the party subject to such
proceeding upon written request therefor by the non-subject party.
(c) In the event Dyax shall be the Insolvent Party and Amgen elects to
terminate this Agreement pursuant to this Section 9.4, all rights and
obligations other
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Confidential material omitted and filed separately with the Securities and
Exchange Commission. Asterisks denote such omissions.
than those which survive in accordance with Section 9.6 hereunder shall
terminate, provided, however, Amgen shall retain all licenses granted herein
*************.
9.5 Effect of Certain Terminations. Upon the earlier termination of this
Agreement by Amgen pursuant to Section 9.2 or by Dyax pursuant to Section 9.3(c)
or 9.4, the following rights and obligations shall apply:
(a) Neither party hereto shall be released from any liability which, at
the time of such termination, shall have already accrued to the other party or
which shall be attributable to a period prior to such termination nor preclude
either party from pursuing any rights and remedies it may have hereunder or at
law or in equity with respect to any breach of this Agreement; and
(b) Amgen shall dispose of any unused Licensed Dyax Material and shall
have the right to sell or otherwise dispose of any finished Licensed Products
then on hand, and to manufacture, use and/or sell or otherwise dispose of any
raw materials, work-in-process, finished goods, returned and repossessed goods,
and materials of any kind, nature or description used in the manufacture of any
Licensed Products subject to such terminated license then on hand; and
(c) ************* this Section 9.5, and the rights and obligations
thereunder and hereunder, shall remain in full force and effect in accordance
with their respective terms without termination or expiration except as
expressly provided therein, and Sections 7 and 8 shall remain in full force and
effect for a period of ************* following termination or expiration of this
Agreement.
9.6 Effect of Expiration or Certain Terminations. Upon the expiration of
the Term or the earlier termination of this Agreement by Amgen pursuant to
Section 9.3(b) or 9.4, the following rights and obligations shall apply:
(a) Neither party hereto shall be released from any liability which, at
the time of such termination, shall have already accrued to the other party or
which shall be attributable to a period prior to such termination nor preclude
either party from pursuing any rights and remedies it may have hereunder or at
law or in equity with respect to any breach of this Agreement; and
(b) ************* this Section 9.6, and the rights and obligations
thereunder and hereunder, shall remain in full force and effect in accordance
with their respective terms without termination or expiration except as
expressly provided therein, and Sections 7 and 8 shall remain in full force and
effect for a period of ************* following termination or expiration of this
Agreement.
10. MISCELLANEOUS
10.1 Severability. If any provision in this Agreement is, for any reason,
held to be void or of no effect, it shall not affect the validity of the
remaining provisions of
12
this Agreement, except in the case the absence of such void provision would make
the entire Agreement unworkable.
10.2 Governing Law. This Agreement shall be governed by the laws of the
State of California, without reference to the conflicts of law principles
thereof, and the patent laws of the United States of America. The parties hereto
hereby consent to the jurisdiction and venue of the state and federal courts
located in the State of California, notwithstanding the fact that either party
may now be or hereafter become domiciled in a different state.
10.3 Notices. All notices, requests, approval or consent, and other
communications hereunder shall be deemed to have been sufficiently given if in
writing and shall be personally delivered or sent by facsimile transmission
(receipt verified), or by registered or certified mail (return receipt
requested), postage prepaid, commercial overnight courier, in each case to the
respective address specified below, or such other address as may be specified in
writing to the other party hereto.
13
If to Amgen: If to Dyax:
Senior Vice President, Corporate Chief Executive Officer
Development, General Counsel Dyax Corp.
and Secretary One Xxxxxxx Square
Amgen Inc. Building 000
Xxx Xxxxx Xxxxxx Xxxxx Xxxxx 000
Thousand Oaks, CA 91320-1799 Xxxxxxxxx, XX 00000
Facsimile: (000) 000-0000 Facsimile: (000) 000-0000
With Copy To:
Senior Vice President, Research
10.4 Entire Agreement. This Agreement (including all Exhibits attached
hereto, which are incorporated herein by reference) is a complete integration of
the entire understanding of the parties with respect to its subject matter, and
no prior representations, promises or understanding related to this subject
matter, which are not incorporated in this Agreement shall be binding upon the
parties.
10.5 Assignment. This Agreement shall not be assignable by either party to
any Third Party hereto without the written consent of the other party; provided,
however, a party may assign this Agreement and all of its rights and obligations
under this Agreement, without such consent, to an entity that acquires all or
substantially all of its business or assets to which this Agreement pertains
(including, with respect to Dyax, an entity that acquires all of the Licensed
Patents), whether by merger, consolidation, reorganization, acquisition, sale or
otherwise. Notwithstanding the restrictions in this Section 10.5, no provision
of this Agreement shall be deemed to restrict Amgen's ability to sublicense any
or all of its rights in or to any Licensed Product or any other Amgen Property.
This Agreement shall be binding upon and inure to the benefit of the parties and
their successors and assigns, and the name of a party appearing herein shall be
deemed to include the names of such party's successors and permitted assigns to
the extent necessary to carry out the intent of this Agreement. Any assignment
not in accordance with this Section 10.5 shall be void.
10.6 Independent Contractors. The parties are independent contractors.
This Agreement shall not be interpreted as making either party the agent,
partner, joint venture or employee of the other. No association, combination or
relation is created between the parties, except as expressly provided.
10.7 Counterparts. This Agreement may be executed in one or more
counterparts, each of which shall be deemed an original, but all of which
together shall constitute one and the same instrument.
10.8 No Third-Party Beneficiaries. The parties specifically disavow any
desire or intention to create a "third party" beneficiary contract, and
specifically declare
14
Confidential material omitted and filed separately with the Securities and
Exchange Commission. Asterisks denote such omissions.
that no Person, except for the parties and their permitted assigns, shall have
any rights hereunder nor any right of enforcement hereof.
10.9 Public Announcements. Except as otherwise required by law or
regulation (and in such event only after compliance with the terms of this
Section 10.9), neither party shall issue a press release or make any other
disclosure of the existence or of the terms of this Agreement, or otherwise use
the name or trademarks or products of the other party or the names of any
employees thereof, without the prior approval of such press release or
disclosure by the other party hereto. Each party shall submit any such press
release or disclosure to the other party, and the receiving party shall have
************* to review and approve any such press release or disclosure, which
approval shall not be unreasonably withheld. If the receiving party does not
respond within such ************* period, the press release or disclosure shall
be deemed approved. In addition if, in the reasonable opinion of such party's
counsel, a public disclosure shall be required by law, regulation or court
order, including without limitation in a filing with the United States
Securities and Exchange Commission or the United States Food and Drug
Administration, the disclosing party shall provide copies of the disclosure
reasonably in advance of such filing or other disclosure for the nondisclosing
party's prior review and comment, and the nondisclosing party shall provide its
comments, if any, on such announcement as soon as practicable. Notwithstanding
the foregoing, Amgen agrees that Dyax may include Amgen on a list that names
Dyax licensees.
15
IN WITNESS WHEREOF, the parties, having read the terms of this Agreement
and intending to be legally bound, execute this Agreement effective the day and
year first above written.
DYAX CORP., a Delaware corporation
By: /s/ L. Xxxxxx Xxxxxx
--------------------------------------------------
L. Xxxxxx Xxxxxx, Executive Vice President
AMGEN INC., a Delaware corporation
By: /s/ Xxxxxxxx X. Xxxxx
--------------------------------------------------
Xxxxxxxx X. Xxxxx, Senior Vice President, Research
16
Confidential material omitted and filed separately with the Securities and
Exchange Commission. Asterisks denote such omissions.
EXHIBIT A
Licensed Patents
================================================================================
Application/
Country Patent No. Filing Date Patent No. Issue Date
------- ---------- ----------- ---------- ----------
--------------------------------------------------------------------------------
US 07/664,989* 3/1/91 5,223,409 6/29/93
--------------------------------------------------------------------------------
US 9,319 1/26/93 5,403,484 4/4/95
--------------------------------------------------------------------------------
US 08/057,667 6/18/93 5,571,698 11/5/96
--------------------------------------------------------------------------------
US div 08/415,922 4/3/95 5,837,500 11/17/98
--------------------------------------------------------------------------------
US div 08/993,776 12/18/97
--------------------------------------------------------------------------------
US div ************* 11/16/98
--------------------------------------------------------------------------------
US div ************* 11/16/98
--------------------------------------------------------------------------------
PCT US89/03731 9/1/89
W09002809 pub 3/22/90
--------------------------------------------------------------------------------
EPO 89/910702.3 9/1/89 436,597 4/2/97
EP436597 pub 7/17/91
--------------------------------------------------------------------------------
EPO div 96/112867.5 8/9/96 Allowed
************* 4/16/97 pub
--------------------------------------------------------------------------------
Japan 89510087 9/1/89
JP4502700 (pub) 5/21/92
--------------------------------------------------------------------------------
Canada 610,176 9/1/89 1,340,288 12/29/98
--------------------------------------------------------------------------------
Ireland IR89/2834 9/4/89
--------------------------------------------------------------------------------
Xxxxxx 00000 9/1/89 91501 6/11/98
--------------------------------------------------------------------------------
Israel 3 divs 5/29/97
--------------------------------------------------------------------------------
PCT US92/01456 2/27/92
W09215677 (pub) 9/17/92
--------------------------------------------------------------------------------
EPO 92/908057.0 2/27/92
--------------------------------------------------------------------------------
Canada 2105300 2/27/92
--------------------------------------------------------------------------------
Japan 92507558 2/27/92
--------------------------------------------------------------------------------
PCT US92/01539 2/28/92
X00000000 (pub) 9/17/92
================================================================================
Confidential material omitted and filed separately with the Securities and
Exchange Commission. Asterisks denote such omissions.
================================================================================
EPO 92/908799.7 2/28/92
--------------------------------------------------------------------------------
Canada 2105303 2/28/92
--------------------------------------------------------------------------------
Japan 92508216 2/28/92
--------------------------------------------------------------------------------
EPO ************* 5/18/99**
================================================================================
* CIP of US Serial No. 487,063 filed 3/2/90 which is a CIP of US Serial No.
240,160 filed 9/2/88. All Protein Engineering Corporation patent rights have
been assigned to Dyax Corp.
** Application assigned to TargetQuest B.V., a wholly-owned subsidiary of
Dyax Corp.
Confidential material omitted and filed separately with the Securities and
Exchange Commission. Asterisks denote such omissions.
EXHIBIT B
New Material
*************
Confidential material omitted and filed separately with the Securities and
Exchange Commission. Asterisks denote such omissions.
EXHIBIT C
Original Material
*************
